Published in J Neurosci on October 01, 2002
Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression. PLoS Genet (2008) 1.64
Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest (2004) 1.34
Target identification for CNS diseases by transcriptional profiling. Neuropsychopharmacology (2008) 1.32
Oxidative damage to RNA: mechanisms, consequences, and diseases. Cell Mol Life Sci (2010) 1.29
Neuroprotection by PGE2 receptor EP1 inhibition involves the PTEN/AKT pathway. Neurobiol Dis (2007) 1.16
A BAD link to mitochondrial cell death in the cochlea of mice with noise-induced hearing loss. J Neurosci Res (2006) 1.13
In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. J Cereb Blood Flow Metab (2011) 1.11
Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation. Cell Commun Signal (2009) 1.05
Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus. Cell Death Differ (2009) 1.03
Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? Int J Physiol Pathophysiol Pharmacol (2009) 1.03
ACh receptors link two signaling pathways to neuroprotection against glutamate-induced excitotoxicity in isolated RGCs. J Neurochem (2009) 1.02
Bcl-w protects hippocampus during experimental status epilepticus. Am J Pathol (2007) 1.01
Bim, Bad, and Bax: a deadly combination in epileptic seizures. J Clin Invest (2004) 0.96
Cell signaling underlying epileptic behavior. Front Behav Neurosci (2011) 0.96
Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells. PLoS Pathog (2009) 0.94
Closing the phenotypic gap between transformed neuronal cell lines in culture and untransformed neurons. J Neurosci Methods (2008) 0.91
Cell type-specific action of seizure-induced intracellular zinc accumulation in the rat hippocampus. J Physiol (2005) 0.89
Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis. Am J Pathol (2009) 0.89
Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts. Front Cell Neurosci (2013) 0.87
13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3. PLoS One (2013) 0.86
The potential role of mitochondrial dysfunction in seizure-associated cell death in the hippocampus and epileptogenesis. J Bioenerg Biomembr (2010) 0.85
Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus. J Neuroinflammation (2012) 0.84
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS One (2013) 0.84
Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death. J Neural Transm (Vienna) (2014) 0.83
Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons. Neurochem Res (2010) 0.82
Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes. Korean J Physiol Pharmacol (2008) 0.80
Grape seed extract prevents skeletal muscle wasting in interleukin 10 knockout mice. BMC Complement Altern Med (2014) 0.79
A Molecular Approach to Epilepsy Management: from Current Therapeutic Methods to Preconditioning Efforts. Mol Neurobiol (2014) 0.78
Naoxintong Protects Primary Neurons from Oxygen-Glucose Deprivation/Reoxygenation Induced Injury through PI3K-Akt Signaling Pathway. Evid Based Complement Alternat Med (2016) 0.78
The silence of p66(Shc) in HCT8 cells inhibits the viability via PI3K/AKT/Mdm-2/p53 signaling pathway. Int J Clin Exp Pathol (2015) 0.75
Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents. Neuropsychiatr Dis Treat (2009) 0.75
Role of phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular trafficking. Life Sci (2016) 0.75
Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium. Drug Des Devel Ther (2015) 0.75
Effect of baicalin on hippocampal damage in kainic acid-induced epileptic mice. Exp Ther Med (2016) 0.75
Role of TLR4-Mediated PI3K/AKT/GSK-3β Signaling Pathway in Apoptosis of Rat Hepatocytes. Biomed Res Int (2015) 0.75
Expression and clinical significance of the phosphatidylinositol 3-kinase/protein kinase B signal transduction pathway in non-small cell lung carcinoma. Oncol Lett (2014) 0.75
Metabolic and Homeostatic Changes in Seizures and Acquired Epilepsy-Mitochondria, Calcium Dynamics and Reactive Oxygen Species. Int J Mol Sci (2017) 0.75
Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell (2004) 6.15
Ischemic tolerance and endogenous neuroprotection. Trends Neurosci (2003) 3.44
Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states. Lancet (2003) 3.36
Mechanisms of ischemic brain damage. Neuropharmacology (2008) 2.40
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice. J Clin Invest (2008) 1.86
In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab (2007) 1.82
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain (2006) 1.82
Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke (2004) 1.79
Toll-like receptor 9: a new target of ischemic preconditioning in the brain. J Cereb Blood Flow Metab (2008) 1.79
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol (2007) 1.68
Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis. Stroke (2007) 1.64
CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.60
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. J Cereb Blood Flow Metab (2007) 1.55
Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex. J Cereb Blood Flow Metab (2009) 1.52
miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. Am J Pathol (2011) 1.52
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants. Brain (2007) 1.50
Visualizing the dynamics of cerebral aneurysms with four-dimensional computed tomographic angiography. Neurosurgery (2005) 1.49
Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels. J Neurosci (2004) 1.40
Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto's encephalopathy. FEBS Lett (2002) 1.37
Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J Neurosci (2011) 1.35
Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest (2004) 1.34
Neuroprotection by osteopontin in stroke. J Cereb Blood Flow Metab (2005) 1.33
Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal (2010) 1.31
Transgenic overexpression of adenosine kinase aggravates cell death in ischemia. J Cereb Blood Flow Metab (2006) 1.30
Lentiviral RNAi-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: a novel perspective for seizure control. Exp Neurol (2007) 1.27
Adenosine dysfunction in astrogliosis: cause for seizure generation? Neuron Glia Biol (2007) 1.23
Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain. Aging Cell (2004) 1.21
Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Res (2008) 1.18
Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism. J Cereb Blood Flow Metab (2007) 1.18
Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke. J Cereb Blood Flow Metab (2008) 1.16
Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis (2008) 1.16
Acid sensing ion channels--novel therapeutic targets for ischemic brain injury. Front Biosci (2007) 1.13
A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a. J Biol Chem (2007) 1.13
A new model of cortical stroke in the rhesus macaque. J Cereb Blood Flow Metab (2009) 1.13
Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms. Stroke (2012) 1.13
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci (2011) 1.12
Periprocedural hemodynamic instability with carotid angioplasty and stenting. Surg Neurol (2008) 1.12
Epilepsy and apoptosis pathways. J Cereb Blood Flow Metab (2005) 1.11
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. PLoS One (2012) 1.10
Proton-gated channels in PC12 cells. J Neurophysiol (2002) 1.10
Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH. J Biol Chem (2006) 1.09
Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain. J Cereb Blood Flow Metab (2008) 1.08
Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death. J Neurosci (2004) 1.07
Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Exp Neurol (2012) 1.07
Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. Eur J Neurosci (2003) 1.07
Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking. J Biol Chem (2010) 1.05
Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. J Neurosci Res (2002) 1.05
Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance. Brain Res (2009) 1.05
Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants. J Cereb Blood Flow Metab (2006) 1.04
Genomics of preconditioning. Stroke (2004) 1.04
Tenascin-C enhances crosstalk signaling of integrin αvβ3/PDGFR-β complex by SRC recruitment promoting PDGF-induced proliferation and migration in smooth muscle cells. J Cell Physiol (2011) 1.01
Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism. Stroke (2012) 1.00
Endoplasmic reticulum stress and apoptosis signaling in human temporal lobe epilepsy. J Neuropathol Exp Neurol (2006) 0.99
Expression of death-associated protein kinase and recruitment to the tumor necrosis factor signaling pathway following brief seizures. J Neurochem (2003) 0.98
Ischemic preconditioning in the rat brain enhances the repair of endogenous oxidative DNA damage by activating the base-excision repair pathway. J Cereb Blood Flow Metab (2006) 0.97
Intracranial heme metabolism and cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Stroke (2003) 0.97
Cerebrospinal fluid ferritin in chronic hydrocephalus after aneurysmal subarachnoid hemorrhage. J Neurol (2006) 0.96
Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice. Neuron Glia Biol (2009) 0.96
Acid-sensing ion channels in acidosis-induced injury of human brain neurons. J Cereb Blood Flow Metab (2010) 0.96
Altered biosynthesis of neuropeptide processing enzyme carboxypeptidase E after brain ischemia: molecular mechanism and implication. J Cereb Blood Flow Metab (2004) 0.95
Adenosine kinase determines the degree of brain injury after ischemic stroke in mice. J Cereb Blood Flow Metab (2011) 0.95
Densin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1. Genes Cells (2002) 0.95
Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody. J Biochem (2004) 0.94
Development of a model of seizure-induced hippocampal injury with features of programmed cell death in the BALB/c mouse. J Neurosci Res (2004) 0.94
Beta-tricalcium phosphate as a substitute for autograft in interbody fusion cages in the canine lumbar spine. J Neurosurg (2002) 0.92
Local disruption of glial adenosine homeostasis in mice associates with focal electrographic seizures: a first step in epileptogenesis? Glia (2011) 0.91
Evidence of tumor necrosis factor receptor 1 signaling in human temporal lobe epilepsy. Exp Neurol (2006) 0.91
Imatinib mesylate prevents cerebral vasospasm after subarachnoid hemorrhage via inhibiting tenascin-C expression in rats. Neurobiol Dis (2012) 0.91
Acidosis decreases low Ca(2+)-induced neuronal excitation by inhibiting the activity of calcium-sensing cation channels in cultured mouse hippocampal neurons. J Physiol (2003) 0.90
BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor. J Neurochem (2010) 0.90
MRI findings of malignant transformation of epidermoid cyst: case report. J Neurooncol (2006) 0.90
Tolerance to ischemia - an increasingly complex biology. Transl Stroke Res (2013) 0.89
Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons. J Physiol (2010) 0.89
Diffusion-weighted magnetic resonance imaging in carotid angioplasty and stenting with balloon embolic protection devices. Neuroradiology (2006) 0.89
Human eye fields in the frontal lobe as studied by epicortical recording of movement-related cortical potentials. Brain (2004) 0.89
Death-associated protein kinase expression in human temporal lobe epilepsy. Ann Neurol (2004) 0.88
Expression, proteolysis and activation of caspases 6 and 7 during rat C6 glioma cell apoptosis. Neurosci Lett (2002) 0.88