Published in Neurobiol Dis on September 04, 2008
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat Med (2012) 1.92
miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. Am J Pathol (2011) 1.52
In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. J Cereb Blood Flow Metab (2011) 1.11
Identifying targets for preventing epilepsy using systems biology. Neurosci Lett (2011) 1.07
Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Exp Neurol (2012) 1.07
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J (2009) 1.03
Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? Int J Physiol Pathophysiol Pharmacol (2009) 1.03
Genome-wide microRNA profiling of rat hippocampus after status epilepticus induced by amygdala stimulation identifies modulators of neuronal apoptosis. PLoS One (2013) 0.94
MicroRNAs in the pathophysiology and treatment of status epilepticus. Front Mol Neurosci (2013) 0.91
Tolerance to ischemia - an increasingly complex biology. Transl Stroke Res (2013) 0.89
Experimental neonatal status epilepticus and the development of temporal lobe epilepsy with unilateral hippocampal sclerosis. Am J Pathol (2009) 0.89
Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus. Cell Death Dis (2010) 0.89
Genome-wide microRNA expression profiles in hippocampus of rats with chronic temporal lobe epilepsy. Sci Rep (2014) 0.89
Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts. Front Cell Neurosci (2013) 0.87
Role of MicroRNAs in innate neuroprotection mechanisms due to preconditioning of the brain. Front Neurosci (2015) 0.86
Seizure preconditioning and epileptic tolerance: models and mechanisms. Int J Physiol Pathophysiol Pharmacol (2009) 0.85
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS One (2013) 0.84
Can genes modify stroke outcome and by what mechanisms? Stroke (2011) 0.82
Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy. Eur J Neurosci (2013) 0.80
miRNAs: biological and clinical determinants in epilepsy. Front Mol Neurosci (2015) 0.79
microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus. Sci Rep (2015) 0.79
The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. Mol Cell Neurosci (2014) 0.79
Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death. Cell Death Dis (2013) 0.78
Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning. Front Neurol (2015) 0.78
A Molecular Approach to Epilepsy Management: from Current Therapeutic Methods to Preconditioning Efforts. Mol Neurobiol (2014) 0.78
RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep (2017) 0.78
Dynamic changes in DNA methylation in ischemic tolerance. Front Neurol (2015) 0.77
Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance. Int J Physiol Pathophysiol Pharmacol (2011) 0.76
Identification of microRNAs with Dysregulated Expression in Status Epilepticus Induced Epileptogenesis. PLoS One (2016) 0.75
Post-conditioning and reperfusion injury in the treatment of stroke. Dose Response (2014) 0.75
Epigenetic modulation of gene expression governs the brain's response to injury. Neurosci Lett (2015) 0.75
Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell (2004) 6.15
Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci U S A (2003) 3.52
Ischemic tolerance and endogenous neuroprotection. Trends Neurosci (2003) 3.44
Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in hibernation and hypoxia-tolerant states. Lancet (2003) 3.36
Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol (2003) 2.42
Mechanisms of ischemic brain damage. Neuropharmacology (2008) 2.40
Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3. J Biol Chem (2002) 1.96
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat Med (2012) 1.92
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice. J Clin Invest (2008) 1.86
S100B in brain damage and neurodegeneration. Microsc Res Tech (2003) 1.85
In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning. J Cereb Blood Flow Metab (2007) 1.82
Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain (2006) 1.82
Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol (2003) 1.81
Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J (2006) 1.79
Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke (2004) 1.79
Toll-like receptor 9: a new target of ischemic preconditioning in the brain. J Cereb Blood Flow Metab (2008) 1.79
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol (2007) 1.68
To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways. Prog Neurobiol (2003) 1.66
Preconditioning reprograms the response to ischemic injury and primes the emergence of unique endogenous neuroprotective phenotypes: a speculative synthesis. Stroke (2007) 1.64
CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab (2005) 1.60
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc Natl Acad Sci U S A (2007) 1.58
Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. J Cereb Blood Flow Metab (2007) 1.55
Control of motoneuron survival by angiogenin. J Neurosci (2008) 1.53
Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex. J Cereb Blood Flow Metab (2009) 1.52
miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. Am J Pathol (2011) 1.52
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants. Brain (2007) 1.50
Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels. J Neurosci (2004) 1.40
Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury. J Neurosci (2011) 1.35
Bim regulation may determine hippocampal vulnerability after injurious seizures and in temporal lobe epilepsy. J Clin Invest (2004) 1.34
Neuroprotection by osteopontin in stroke. J Cereb Blood Flow Metab (2005) 1.33
Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal (2010) 1.31
Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. J Neurosci (2002) 1.31
Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review. Biochim Biophys Acta (2009) 1.31
Transgenic overexpression of adenosine kinase aggravates cell death in ischemia. J Cereb Blood Flow Metab (2006) 1.30
Lentiviral RNAi-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: a novel perspective for seizure control. Exp Neurol (2007) 1.27
Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD). Mol Biol Cell (2006) 1.26
Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci (2009) 1.24
Adenosine dysfunction in astrogliosis: cause for seizure generation? Neuron Glia Biol (2007) 1.23
Ischemia-induced neurogenesis is preserved but reduced in the aged rodent brain. Aging Cell (2004) 1.21
Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism. J Cereb Blood Flow Metab (2002) 1.20
TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol (2005) 1.19
Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Res (2008) 1.18
Downregulation of hippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism. J Cereb Blood Flow Metab (2007) 1.18
Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance. J Neurosci (2007) 1.18
AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol (2010) 1.17
Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke. J Cereb Blood Flow Metab (2008) 1.16
Acid sensing ion channels--novel therapeutic targets for ischemic brain injury. Front Biosci (2007) 1.13
A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a. J Biol Chem (2007) 1.13
Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis. J Cell Sci (2003) 1.13
A new model of cortical stroke in the rhesus macaque. J Cereb Blood Flow Metab (2009) 1.13
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci (2011) 1.12
Differential DNA methylation patterns define status epilepticus and epileptic tolerance. J Neurosci (2012) 1.12
In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. J Cereb Blood Flow Metab (2011) 1.11
Epilepsy and apoptosis pathways. J Cereb Blood Flow Metab (2005) 1.11
Coincident enrichment of phosphorylated IkappaBalpha, activated IKK, and phosphorylated p65 in the axon initial segment of neurons. Mol Cell Neurosci (2006) 1.11
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. PLoS One (2012) 1.10
Proton-gated channels in PC12 cells. J Neurophysiol (2002) 1.10
Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons. Antioxid Redox Signal (2011) 1.10
Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH. J Biol Chem (2006) 1.09
Ubiquitin-proteasome system as a modulator of cell fate. Curr Opin Pharmacol (2007) 1.09
Proliferating progenitor cells: a required cellular element for induction of ischemic tolerance in the brain. J Cereb Blood Flow Metab (2008) 1.08
Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis. J Biol Chem (2005) 1.08
Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (2007) 1.07
Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death. J Neurosci (2004) 1.07
6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA. J Neurochem (2007) 1.07
Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Exp Neurol (2012) 1.07
Formation of a tumour necrosis factor receptor 1 molecular scaffolding complex and activation of apoptosis signal-regulating kinase 1 during seizure-induced neuronal death. Eur J Neurosci (2003) 1.07
The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics. J Neurochem (2010) 1.06
Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation. J Biol Chem (2008) 1.05
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. J Biol Chem (2001) 1.05
Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking. J Biol Chem (2010) 1.05
Characterization of neuronal death induced by focally evoked limbic seizures in the C57BL/6 mouse. J Neurosci Res (2002) 1.05
Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance. Brain Res (2009) 1.05
Neuroprotection in ischemic mouse brain induced by stem cell-derived brain implants. J Cereb Blood Flow Metab (2006) 1.04
p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones. J Neurochem (2002) 1.04
Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma. J Neurooncol (2007) 1.04
Genomics of preconditioning. Stroke (2004) 1.04
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J (2009) 1.03