Published in Biochemistry on October 15, 2002
Tertiary interactions determine the accuracy of RNA folding. J Am Chem Soc (2008) 1.40
Docking kinetics and equilibrium of a GAAA tetraloop-receptor motif probed by single-molecule FRET. Proc Natl Acad Sci U S A (2005) 1.27
Comprehensive features of natural and in vitro selected GNRA tetraloop-binding receptors. Nucleic Acids Res (2007) 1.20
Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker. Biochemistry (2006) 1.15
Enthalpy-driven RNA folding: single-molecule thermodynamics of tetraloop-receptor tertiary interaction. Biochemistry (2009) 1.10
Generation of a catalytic module on a self-folding RNA. RNA (2004) 1.00
Monovalent and divalent promoted GAAA tetraloop-receptor tertiary interactions from freely diffusing single-molecule studies. Biophys J (2008) 0.99
Removal of covalent heterogeneity reveals simple folding behavior for P4-P6 RNA. J Biol Chem (2011) 0.95
Entropic origin of Mg2+-facilitated RNA folding. Proc Natl Acad Sci U S A (2012) 0.93
Fluorescence of covalently attached pyrene as a general RNA folding probe. Nucleic Acids Res (2006) 0.91
Thermodynamic origins of monovalent facilitated RNA folding. Biochemistry (2012) 0.85
2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA. Chem Biol (2011) 0.81
Putative intermediary stages for the molecular evolution from a ribozyme to a catalytic RNP. Nucleic Acids Res (2003) 0.77
Kinetic and thermodynamic framework for P4-P6 RNA reveals tertiary motif modularity and modulation of the folding preferred pathway. Proc Natl Acad Sci U S A (2016) 0.76
Selective stabilization of natively folded RNA structure by DNA constraints. J Am Chem Soc (2008) 0.75
Deoxyribozymes with 2'-5' RNA ligase activity. J Am Chem Soc (2003) 1.75
Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes. Nat Nanotechnol (2008) 1.63
DNA-catalyzed sequence-specific hydrolysis of DNA. Nat Chem Biol (2009) 1.54
Deoxyribozymes that synthesize branched and lariat RNA. J Am Chem Soc (2003) 1.34
Characterization of deoxyribozymes that synthesize branched RNA. Biochemistry (2003) 1.30
A DNA enzyme that mimics the first step of RNA splicing. Nat Struct Mol Biol (2004) 1.26
DNA-catalyzed formation of nucleopeptide linkages. Angew Chem Int Ed Engl (2008) 1.18
Improvement of DNA adenylation using T4 DNA ligase with a template strand and a strategically mismatched acceptor strand. Bioorg Chem (2007) 1.13
In vitro evolution of an RNA-cleaving DNA enzyme into an RNA ligase switches the selectivity from 3'-5' to 2'-5'. J Am Chem Soc (2003) 1.13
General deoxyribozyme-catalyzed synthesis of native 3'-5' RNA linkages. J Am Chem Soc (2005) 1.13
Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2',3'-cyclic phosphate RNA substrates. Org Biomol Chem (2008) 1.11
Modulation of RNA tertiary folding by incorporation of caged nucleotides. Angew Chem Int Ed Engl (2005) 1.11
A deoxyribozyme that forms a three-helix-junction complex with its RNA substrates and has general RNA branch-forming activity. J Am Chem Soc (2005) 1.09
Directing the outcome of deoxyribozyme selections to favor native 3'-5' RNA ligation. Biochemistry (2005) 1.09
Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine. Biochemistry (2010) 1.07
Efficient RNA 5'-adenylation by T4 DNA ligase to facilitate practical applications. RNA (2006) 1.02
Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA. Nucleic Acids Res (2011) 1.01
DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation. J Am Chem Soc (2008) 1.01
Functional compromises among pH tolerance, site specificity, and sequence tolerance for a DNA-hydrolyzing deoxyribozyme. Biochemistry (2010) 1.00
Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn2+-only) behavior. Chem Commun (Camb) (2010) 0.98
Zn2+-dependent deoxyribozymes that form natural and unnatural RNA linkages. Biochemistry (2005) 0.97
A deoxyribozyme that synthesizes 2',5'-branched RNA with any branch-site nucleotide. Nucleic Acids Res (2005) 0.97
DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates. Biochemistry (2011) 0.97
DNA-catalyzed serine side chain reactivity and selectivity. Chem Commun (Camb) (2010) 0.96
Synthesis of amine- and thiol-modified nucleoside phosphoramidites for site-specific introduction of biophysical probes into RNA. J Org Chem (2005) 0.95
Lanthanide ions as required cofactors for DNA catalysts. Chem Sci (2012) 0.95
Systematic evaluation of the dependence of deoxyribozyme catalysis on random region length. ACS Comb Sci (2012) 0.94
Optimization and generality of a small deoxyribozyme that ligates RNA. J Mol Biol (2003) 0.94
Catalytic DNA with phosphatase activity. Proc Natl Acad Sci U S A (2013) 0.93
Deoxyribozyme-catalyzed labeling of RNA. Angew Chem Int Ed Engl (2007) 0.93
Site-selective depurination by a periodate-dependent deoxyribozyme. Chem Commun (Camb) (2007) 0.92
Adenosine is inherently favored as the branch-site RNA nucleotide in a structural context that resembles natural RNA splicing. Biochemistry (2006) 0.92
Allosteric control of ribozyme catalysis by using DNA constraints. Chembiochem (2007) 0.92
DNA catalysts with tyrosine kinase activity. J Am Chem Soc (2013) 0.92
Efficient one-step synthesis of biologically related lariat RNAs by a deoxyribozyme. Angew Chem Int Ed Engl (2005) 0.92
Fluorescence of covalently attached pyrene as a general RNA folding probe. Nucleic Acids Res (2006) 0.91
DNA constraints allow rational control of macromolecular conformation. J Am Chem Soc (2005) 0.91
Recent advances in DNA catalysis. Biopolymers (2007) 0.88
Parallel selections in vitro reveal a preference for 2'-5' RNA ligation upon deoxyribozyme-mediated opening of a 2',3'-cyclic phosphate. J Mol Evol (2005) 0.88
Structure-function correlations derived from faster variants of a RNA ligase deoxyribozyme. Nucleic Acids Res (2004) 0.87
Mimicking the first step of RNA splicing: an artificial DNA enzyme can synthesize branched RNA using an oligonucleotide leaving group as a 5'-exon analogue. Biochemistry (2005) 0.87
Modulation of DNA constraints that control macromolecular folding. Angew Chem Int Ed Engl (2006) 0.85
DNA-catalyzed reductive amination. Angew Chem Int Ed Engl (2011) 0.85
Covalent tagging of phosphorylated peptides by phosphate-specific deoxyribozymes. Chembiochem (2012) 0.85
A generalizable DNA-catalyzed approach to peptide-nucleic acid conjugation. Chembiochem (2014) 0.84
Rational modification of a selection strategy leads to deoxyribozymes that create native 3'-5' RNA linkages. J Am Chem Soc (2004) 0.84
Engineering a selective small-molecule substrate binding site into a deoxyribozyme. Angew Chem Int Ed Engl (2007) 0.83
Ty1 reverse transcriptase does not read through the proposed 2',5'-branched retrotransposition intermediate in vitro. RNA (2007) 0.83
DNA-catalyzed reactivity of a phosphoramidate functional group and formation of an unusual pyrophosphoramidate linkage. Org Biomol Chem (2011) 0.82
DNA-catalyzed hydrolysis of esters and aromatic amides. J Am Chem Soc (2013) 0.82
Experimental tests of two proofreading mechanisms for 5'-splice site selection. ACS Chem Biol (2006) 0.82
DNA catalysis of a normally disfavored RNA hydrolysis reaction. J Am Chem Soc (2013) 0.82
Improved deoxyribozymes for synthesis of covalently branched DNA and RNA. Nucleic Acids Res (2010) 0.81
Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA. Org Lett (2008) 0.81
DNA-catalyzed lysine side chain modification. Angew Chem Int Ed Engl (2014) 0.80
A general two-step strategy to synthesize lariat RNAs. RNA (2005) 0.80
A simple molecular model for thermophilic adaptation of functional nucleic acids. Biochemistry (2007) 0.78
A modular tyrosine kinase deoxyribozyme with discrete aptamer and catalyst domains. Chem Commun (Camb) (2014) 0.78
Synthesis and application of a 5'-aldehyde phosphoramidite for covalent attachment of DNA to biomolecules. J Org Chem (2006) 0.78
Efficient control of group I intron ribozyme catalysis by DNA constraints. Chem Commun (Camb) (2009) 0.77
Selective stabilization of natively folded RNA structure by DNA constraints. J Am Chem Soc (2008) 0.75
DNA-catalyzed glycosylation using aryl glycoside donors. Chem Commun (Camb) (2016) 0.75
Selective functionalization: Shields for small molecules. Nat Chem (2012) 0.75
Site-specific fluorescent labeling of large RNAs with pyrene. Curr Protoc Nucleic Acid Chem (2004) 0.75