Published in J Biol Chem on October 09, 2002
Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog Retin Eye Res (2006) 2.49
Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J Cell Biol (2003) 1.99
Three-dimensional evaluation of retinal ganglion cell axon regeneration and pathfinding in whole mouse tissue after injury. Exp Neurol (2013) 1.23
Guidance molecules in axon pruning and cell death. Cold Spring Harb Perspect Biol (2010) 1.13
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex. Nat Struct Mol Biol (2012) 1.07
Neuropilin-1 is a direct target of the transcription factor E2F1 during cerebral ischemia-induced neuronal death in vivo. Mol Cell Biol (2006) 0.92
Impediments to eye transplantation: ocular viability following optic-nerve transection or enucleation. Br J Ophthalmol (2009) 0.89
Neuropilin 1 directly interacts with Fer kinase to mediate semaphorin 3A-induced death of cortical neurons. J Biol Chem (2010) 0.89
Slit/Robo pathway: a promising therapeutic target for cancer. Drug Discov Today (2014) 0.87
Modulating Sema3A signal with a L1 mimetic peptide is not sufficient to promote motor recovery and axon regeneration after spinal cord injury. Mol Cell Neurosci (2007) 0.85
Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins. J Neuroinflammation (2007) 0.82
NRP1 function and targeting in neurovascular development and eye disease. Prog Retin Eye Res (2016) 0.82
A perspective on the role of class III semaphorin signaling in central nervous system trauma. Front Cell Neurosci (2014) 0.80
Changes in expression of Class 3 Semaphorins and their receptors during development of the rat retina and superior colliculus. BMC Dev Biol (2014) 0.77
Sema-3A indirectly disrupts the regeneration process of goldfish optic nerve after controlled injury. Graefes Arch Clin Exp Ophthalmol (2010) 0.77
Upregulation of Semaphorin 3A and the associated biochemical and cellular events in a rat model of retinal detachment. Graefes Arch Clin Exp Ophthalmol (2008) 0.77
Up-regulation of semaphorin expression in retina of glaucomatous rabbits. Graefes Arch Clin Exp Ophthalmol (2003) 0.75
Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons. Development (2016) 0.75
Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1. J Neurosci (2016) 0.75
Sema3A Reduces Sprouting of Adult Rod Photoreceptors In Vitro. Invest Ophthalmol Vis Sci (2017) 0.75
Nicotinamide and WLD(S) Act Together to Prevent Neurodegeneration in Glaucoma. Front Neurosci (2017) 0.75
A double-blind, delayed-start trial of rasagiline in Parkinson's disease. N Engl J Med (2009) 5.81
VPS35 mutations in Parkinson disease. Am J Hum Genet (2011) 4.16
Levodopa in the treatment of Parkinson's disease: current controversies. Mov Disord (2004) 2.90
The natural history of multiple system atrophy: a prospective European cohort study. Lancet Neurol (2013) 2.65
The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy. J Neurol (2004) 2.40
Validation of the freezing of gait questionnaire in patients with Parkinson's disease. Mov Disord (2009) 1.90
Antioxidant therapy in acute central nervous system injury: current state. Pharmacol Rev (2002) 1.76
Handedness as a predictor of side of onset of Parkinson's disease. Parkinsonism Relat Disord (2008) 1.74
A double-blind, delayed-start trial of rasagiline in Parkinson's disease (the ADAGIO study): prespecified and post-hoc analyses of the need for additional therapies, changes in UPDRS scores, and non-motor outcomes. Lancet Neurol (2011) 1.68
Lesions outside the CNS in Parkinson's disease. Mov Disord (2009) 1.55
The mystery of motor asymmetry in Parkinson's disease. Lancet Neurol (2006) 1.55
Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model. Exp Neurol (2006) 1.47
The "dying-back" phenomenon of motor neurons in ALS. J Mol Neurosci (2010) 1.45
The hyperperfusion syndrome: an under-recognized complication of carotid endarterectomy. Isr Med Assoc J (2004) 1.40
The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle. DNA Repair (Amst) (2008) 1.32
Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells. J Biol Chem (2006) 1.27
18F-ML-10, a PET tracer for apoptosis: first human study. J Nucl Med (2011) 1.26
Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase. J Mol Neurosci (2002) 1.25
The etiopathogenesis of Parkinson disease and suggestions for future research. Part I. J Neuropathol Exp Neurol (2007) 1.21
Clinicogenetic study of mutations in LRRK2 exon 41 in Parkinson's disease patients from 18 countries. Mov Disord (2006) 1.20
From the Gla domain to a novel small-molecule detector of apoptosis. Cell Res (2009) 1.19
Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection. Invest Ophthalmol Vis Sci (2010) 1.18
Human mesenchymal stem cells express neural genes, suggesting a neural predisposition. Stem Cells Dev (2006) 1.17
Dependency between light intensity and refractive development under light-dark cycles. Exp Eye Res (2010) 1.16
[123I]-FP/CIT SPECT imaging for distinguishing drug-induced parkinsonism from Parkinson's disease. Mov Disord (2006) 1.14
Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization. Eur J Immunol (2006) 1.14
Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases. Expert Opin Biol Ther (2009) 1.13
DJ-1 protects against dopamine toxicity. J Neural Transm (Vienna) (2008) 1.11
Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. Neurotoxicology (2008) 1.07
Introducing transcription factors to multipotent mesenchymal stem cells: making transdifferentiation possible. Stem Cells (2009) 1.07
Apoptosis and Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry (2003) 1.06
Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis (2006) 1.05
Donor scleral patch for treating hypotony due to leaking and/or overfiltering blebs. J Glaucoma (2005) 1.03
Protective effects of neurotrophic factor-secreting cells in a 6-OHDA rat model of Parkinson disease. Stem Cells Dev (2009) 1.03
Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with ¹⁸F-ML-10. Eur J Nucl Med Mol Imaging (2012) 1.03
Minocycline delays death of retinal ganglion cells in experimental glaucoma and after optic nerve transection. Arch Ophthalmol (2006) 1.03
Induction of human mesenchymal stem cells into dopamine-producing cells with different differentiation protocols. Stem Cells Dev (2008) 1.01
Inter-device variability of the Stratus optical coherence tomography. Am J Ophthalmol (2008) 1.01
Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease. Trends Mol Med (2003) 1.00
Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons. J Neurosci (2006) 1.00
A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis. J Neurochem (2004) 1.00
Mechanism of retinal ganglion cells death in secondary degeneration of the optic nerve. Exp Eye Res (2009) 0.99
The transcription factor c-jun is activated in retinal ganglion cells in experimental rat glaucoma. Exp Eye Res (2005) 0.99
Intraocular pressure elevation within the first 24 hours after cataract surgery in patients with glaucoma or exfoliation syndrome. Ophthalmology (2007) 0.99
Small-molecule biomarkers for clinical PET imaging of apoptosis. J Nucl Med (2010) 0.99
Mesenchymal stem cells stimulate endogenous neurogenesis in the subventricular zone of adult mice. Stem Cell Rev (2011) 0.98
Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis. Brain Res (2003) 0.98
Therapeutic potential of neurotrophic factors in neurodegenerative diseases. BioDrugs (2005) 0.97
Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant. J Mol Neurosci (2008) 0.97
Twenty-four-hour intraocular pressure control with bimatoprost and the bimatoprost/timolol fixed combination administered in the morning, or evening in exfoliative glaucoma. Br J Ophthalmol (2009) 0.97
Differentiated mesenchymal stem cells for sciatic nerve injury. Stem Cell Rev (2011) 0.96
Wnt signaling enhances neurogenesis and improves neurological function after focal ischemic injury. PLoS One (2012) 0.96
Neurogenesis in the aged and neurodegenerative brain. Apoptosis (2010) 0.96
Antioxidant treatment in Alzheimer's disease: current state. J Mol Neurosci (2003) 0.96
A novel immune-based therapy for stroke induces neuroprotection and supports neurogenesis. Stroke (2007) 0.96
Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe. J Neurotrauma (2008) 0.95
Lentiviral delivery of LMX1a enhances dopaminergic phenotype in differentiated human bone marrow mesenchymal stem cells. Stem Cells Dev (2009) 0.95
Regulation of cell death and survival pathways in experimental glaucoma. Exp Eye Res (2007) 0.95
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. J Biol Chem (2001) 0.95
DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS. J Mol Neurosci (2008) 0.94
Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains. J Biol Chem (2002) 0.94
Molecular imaging of neurovascular cell death in experimental cerebral stroke by PET. J Nucl Med (2008) 0.94
123I-FP-CIT SPECT imaging of dopamine transporters in patients with cerebrovascular disease and clinical diagnosis of vascular parkinsonism. J Nucl Med (2004) 0.93
Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis (2009) 0.93
Ambient illuminance, retinal dopamine release and refractive development in chicks. Exp Eye Res (2012) 0.93
Intracerebroventricular transplantation of human mesenchymal stem cells induced to secrete neurotrophic factors attenuates clinical symptoms in a mouse model of multiple sclerosis. J Mol Neurosci (2009) 0.93
Transplantation of placenta-derived mesenchymal stem cells in the EAE mouse model of MS. J Mol Neurosci (2012) 0.92
Experimental glaucoma and optic nerve transection induce simultaneous upregulation of proapoptotic and prosurvival genes. Invest Ophthalmol Vis Sci (2006) 0.92
Induction of adult human bone marrow mesenchymal stromal cells into functional astrocyte-like cells: potential for restorative treatment in Parkinson's disease. J Mol Neurosci (2009) 0.92
Oxidative stress, induced by 6-hydroxydopamine, reduces proteasome activities in PC12 cells: implications for the pathogenesis of Parkinson's disease. J Mol Neurosci (2004) 0.92
Trial designs used to study neuroprotective therapy in Parkinson's disease. Mov Disord (2012) 0.91
Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging. Stem Cells (2008) 0.91
Axonal damage is reduced following glatiramer acetate treatment in C57/bl mice with chronic-induced experimental autoimmune encephalomyelitis. Neurosci Res (2003) 0.90
Mammalian meiosis involves DNA double-strand breaks with 3' overhangs. Chromosoma (2003) 0.89
ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis. Eur J Nucl Med Mol Imaging (2005) 0.89
A novel thiol antioxidant that crosses the blood brain barrier protects dopaminergic neurons in experimental models of Parkinson's disease. Eur J Neurosci (2005) 0.89
Gold Micro-Shunt Implants Versus Ahmed Glaucoma Valve: Long-term Outcomes of a Prospective Randomized Clinical Trial. J Glaucoma (2016) 0.88
Docosahexaenoic acid and arachidonic acid are fundamental supplements for the induction of neuronal differentiation. J Lipid Res (2006) 0.88
Intraocular pressure measurements and biomechanical properties of the cornea in eyes after penetrating keratoplasty. Am J Ophthalmol (2011) 0.88
Role of DJ-1 in Parkinson's disease. J Mol Neurosci (2006) 0.88
CuZn-SOD deficiency, rather than overexpression, is associated with enhanced recovery and attenuated activation of NF-kappaB after brain trauma in mice. J Cereb Blood Flow Metab (2006) 0.88
Novel molecular imaging of cell death in experimental cerebral stroke. Brain Res (2007) 0.87
Adult neurotrophic factor-secreting stem cells: a potential novel therapy for neurodegenerative diseases. Isr Med Assoc J (2009) 0.87
MRI evidence of white matter damage in a mouse model of Nijmegen breakage syndrome. Exp Neurol (2007) 0.87
Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage. Neurosci Lett (2006) 0.86
Dopaminergic differentiation of human mesenchymal stem cells--utilization of bioassay for tyrosine hydroxylase expression. Neurosci Lett (2007) 0.86
The etiopathogenesis of Parkinson disease and suggestions for future research. Part II. J Neuropathol Exp Neurol (2007) 0.86
Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia. Hum Mol Genet (2005) 0.86
Hemin-induced apoptosis in PC12 and neuroblastoma cells: implications for local neuronal death associated with intracerebral hemorrhage. Neurotox Res (2003) 0.85
Unilateral lower limb rest tremor is not necessarily a presenting symptom of Parkinson's disease. Mov Disord (2010) 0.85
Selective laser trabeculoplasty in uncontrolled pseudoexfoliation glaucoma. Ophthalmic Surg Lasers Imaging (2011) 0.85
Familial Parkinsonism with digenic parkin and PINK1 mutations. Mov Disord (2008) 0.85
Wnt signaling pathway overcomes the disruption of neuronal differentiation of neural progenitor cells induced by oligomeric amyloid β-peptide. J Neurochem (2011) 0.85