Published in Hum Pathol on September 01, 2002
Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines. Cell Cycle (2010) 2.19
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest (2006) 2.03
MicroRNAs involved in tumor suppressor and oncogene pathways: implications for hepatobiliary neoplasia. Hepatology (2009) 1.34
Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract. J Exp Clin Cancer Res (2009) 1.12
Molecular pathogenesis of cholangiocarcinoma. Int J Hepatol (2011) 1.02
The challenge of cholangiocarcinoma: dissecting the molecular mechanisms of an insidious cancer. Dis Model Mech (2013) 1.01
Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer. FEBS Lett (2012) 0.98
SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma. Oncogene (2014) 0.89
New advances in the management of biliary tract cancer. HPB (Oxford) (2007) 0.88
Effect of transforming growth factor-beta1 on human intrahepatic cholangiocarcinoma cell growth. World J Gastroenterol (2006) 0.86
Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. Dig Liver Dis (2012) 0.82
Molecular mechanisms of cholangiocarcinoma. World J Gastrointest Pathophysiol (2010) 0.82
Alterations of gene expression of RB pathway in Opisthorchis viverrini infection-induced cholangiocarcinoma. Parasitol Res (2009) 0.80
Immunohistochemical expression of SMAD4, CK19, and CA19-9 in fine needle aspiration samples of pancreatic adenocarcinoma: Utility and potential role. Cytojournal (2007) 0.79
The significance of genetics for cholangiocarcinoma development. Ann Transl Med (2013) 0.78
miRNA-558 promotes gastric cancer progression through attenuating Smad4-mediated repression of heparanase expression. Cell Death Dis (2016) 0.78
[Precursor lesions of pancreatobiliary cancer]. Pathologe (2011) 0.78
Association of cyclin D1, p16 and retinoblastoma protein expressions with prognosis and metastasis of gallbladder carcinoma. World J Gastroenterol (2005) 0.77
SMAD4 protein expression and cell proliferation in colorectal adenocarcinomas. Virchows Arch (2011) 0.76
Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas. World J Gastrointest Oncol (2016) 0.75
Targeted therapy in biliary tract cancers-current limitations and potentials in the future. J Gastrointest Oncol (2017) 0.75
Aberrant CpG island hypermethylation along multistep hepatocarcinogenesis. Am J Pathol (2003) 2.36
The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma. J Hepatol (2008) 2.03
Stage migration effect on survival in gastric cancer surgery with extended lymphadenectomy: the reappraisal of positive lymph node ratio as a proper N-staging. Ann Surg (2012) 1.96
Multicenter analysis of clinicopathologic features of intraductal papillary mucinous tumor of the pancreas: is it possible to predict the malignancy before surgery? Ann Surg Oncol (2005) 1.95
Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol (2003) 1.86
Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma. Cancer Res (2010) 1.82
Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol (2002) 1.82
Current Trends of the Incidence and Pathological Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) in Korea 2000-2009: Multicenter Study. Cancer Res Treat (2012) 1.76
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res (2005) 1.70
Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. Gastroenterology (2010) 1.64
Prognostic importance of epithelial-mesenchymal transition-related protein expression in gastric carcinoma. Histopathology (2009) 1.64
Synchronous and metachronous cancers in patients with gastric cancer. J Surg Oncol (2008) 1.62
Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children. Cancer Sci (2009) 1.61
Low Ki-67 proliferation index is an indicator of poor prognosis in gastric cancer. J Surg Oncol (2010) 1.58
Analysis of the lymphatic stream to predict sentinel nodes in gastric cancer patients. Ann Surg Oncol (2013) 1.53
Molecular pathology of gastric carcinoma. Pathobiology (2011) 1.49
Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest (2002) 1.47
Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis. Cancer Res (2008) 1.45
Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary. Hum Pathol (2002) 1.41
E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis. Nat Med (2006) 1.40
Evaluation of HER-2 gene status in gastric carcinoma using immunohistochemistry, fluorescence in situ hybridization, and real-time quantitative polymerase chain reaction. Hum Pathol (2007) 1.36
Protein expression profiling and molecular classification of gastric cancer by the tissue array method. Clin Cancer Res (2007) 1.35
Expression of mucins and cytokeratins in primary carcinomas of the digestive system. Mod Pathol (2003) 1.35
Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. Clin Cancer Res (2004) 1.33
Clinicopathological analysis for recurrence of early gastric cancer. Jpn J Clin Oncol (2003) 1.31
Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood (2002) 1.30
Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma. Am J Pathol (2002) 1.29
Heterogeneous amplification of ERBB2 in primary lesions is responsible for the discordant ERBB2 status of primary and metastatic lesions in gastric carcinoma. Histopathology (2011) 1.29
Clinicopathologic analysis of early ampullary cancers with a focus on the feasibility of ampullectomy. Ann Surg (2005) 1.26
RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma. Cancer Biol Ther (2011) 1.26
Diagnostic accuracy of T and N stages with endoscopy, stomach protocol CT, and endoscopic ultrasonography in early gastric cancer. J Surg Oncol (2009) 1.26
Focal peliosis hepatis as a mimicker of hepatic tumors: radiological-pathological correlation. J Comput Assist Tomogr (2007) 1.25
Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer. Hum Pathol (2011) 1.25
Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death. Exp Mol Med (2007) 1.24
The tissue microarray object model: a data model for storage, analysis, and exchange of tissue microarray experimental data. Arch Pathol Lab Med (2006) 1.22
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res (2005) 1.22
Clinical practice guideline for accurate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea. J Korean Med Sci (2010) 1.21
Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis. APMIS (2003) 1.21
Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol (2011) 1.20
DNA methylation in peripheral blood: a potential biomarker for cancer molecular epidemiology. J Epidemiol (2012) 1.19
Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. Cancer Sci (2003) 1.18
The role of PET/CT in detection of gastric cancer recurrence. BMC Cancer (2009) 1.16
Distinct clinical features and outcomes of gastric cancers with microsatellite instability. Mod Pathol (2002) 1.16
Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res (2007) 1.15
A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer. Virology (2004) 1.15
Clinical practice guideline for accurate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea. Cancer Res Treat (2012) 1.14
Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice. Cancer Res (2005) 1.12
Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. Eur J Cancer (2009) 1.12
Aberrant methylation of p14ARF gene correlates with poor survival in osteosarcoma. Clin Orthop Relat Res (2006) 1.12
Risk factors of residual or recurrent tumor in patients with a tumor-positive resection margin after endoscopic resection of early gastric cancer. Surg Endosc (2012) 1.12
Clinical outcome of pylorus-preserving gastrectomy in gastric cancer in comparison with conventional distal gastrectomy with Billroth I anastomosis. World J Surg (2008) 1.11
Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. Cancer Res (2008) 1.11
Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. BMC Cancer (2008) 1.11
Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach. Cancer (2005) 1.11
Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma. Hum Pathol (2012) 1.08
Current trends in the epidemiological and pathological characteristics of gastrointestinal stromal tumors in Korea, 2003-2004. J Korean Med Sci (2010) 1.08
Identification and characterization of a novel cancer/testis antigen gene CAGE. Biochem Biophys Res Commun (2002) 1.08
Overexpression of clusterin in human hepatocellular carcinoma. Hum Pathol (2004) 1.06
Mucinous gastric carcinomas: clinicopathologic and molecular analyses. Cancer (2009) 1.04
Wnt signaling enhances the activation and survival of human hepatic stellate cells. FEBS Lett (2007) 1.04
Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn (2012) 1.03
Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer. Hum Pathol (2010) 1.03
CpG island hypermethylation and repetitive DNA hypomethylation in premalignant lesion of extrahepatic cholangiocarcinoma. Virchows Arch (2009) 1.02
Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma. Oncol Rep (2009) 1.01
Prognostic significance of CD24 expression in gastric carcinoma. Cancer Res Treat (2004) 1.01
A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer. Carcinogenesis (2007) 1.01
Subclassification of pT2 gastric adenocarcinoma according to depth of invasion (pT2a vs pT2b) and lymph node status (pN). Surgery (2007) 1.00
Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas. Arch Pathol Lab Med (2007) 0.99
Prognostic significance of glutathione peroxidase 1 (GPX1) down-regulation and correlation with aberrant promoter methylation in human gastric cancer. Anticancer Res (2012) 0.99
Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis. PLoS One (2013) 0.99
Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. Cancer Lett (2006) 0.99
Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays. Cancer Lett (2002) 0.99
The value of palliative gastrectomy in gastric cancer with distant metastasis. Ann Surg Oncol (2011) 0.98
Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance. Clin Cancer Res (2005) 0.98
Up-regulated expression of sulfatases (SULF1 and SULF2) as prognostic and metastasis predictive markers in human gastric cancer. J Pathol (2012) 0.98
Epstein-Barr virus and microsatellite instability in gastric carcinogenesis. J Pathol (2003) 0.98
Clinical significance of high focal adhesion kinase gene copy number and overexpression in invasive breast cancer. Breast Cancer Res Treat (2010) 0.98
Histologically proven non-alcoholic fatty liver disease and clinically related factors in recipients after liver transplantation. Clin Transplant (2014) 0.97
Comparative analysis of protein expressions in primary and metastatic gastric carcinomas. Hum Pathol (2008) 0.97
Fatty acid-CoA ligase 4 is overexpressed in human hepatocellular carcinoma. Cancer Sci (2003) 0.97
Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer. Int J Oncol (2007) 0.97
Prognostic significance of microsatellite instability in sporadic colorectal cancer. Int J Colorectal Dis (2004) 0.96
Meta- and gene set analysis of stomach cancer gene expression data. Mol Cells (2007) 0.96
Increased intratumoral lymphatic vessel density correlates with lymph node metastasis in early gastric carcinoma. Ann Surg Oncol (2009) 0.95
LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients. Breast Cancer Res Treat (2013) 0.95
The combined expression of metaplasia biomarkers predicts the prognosis of gastric cancer. Ann Surg Oncol (2011) 0.94
Mutation and altered expression of beta-catenin during gallbladder carcinogenesis. Am J Surg Pathol (2002) 0.94
Cytokeratin expression profile in gastric carcinomas. Hum Pathol (2004) 0.94
Constitutive activation of signal transducers and activators of transcription 3 correlates with better prognosis, cell proliferation and hypoxia-inducible factor-1α in human gastric cancer. Pathobiology (2011) 0.94
COX2 overexpression is a prognostic marker for Stage III breast cancer. Breast Cancer Res Treat (2011) 0.94
Epstein-Barr virus in human malignancy: a special reference to Epstein-Barr virus associated gastric carcinoma. Cancer Res Treat (2005) 0.94
Effects of ERCC1 expression in peripheral blood on the risk of head and neck cancer. Eur J Cancer Prev (2006) 0.93
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression. Cancer Lett (2006) 0.93
Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic marker. Int J Cancer (2013) 0.93
Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. Virchows Arch (2006) 0.93
Manganese superoxide dismutase expression correlates with a poor prognosis in gastric cancer. Pathobiology (2003) 0.93
Hereditary nonpolyposis colorectal cancer in endometrial cancer patients. Int J Cancer (2008) 0.92
Proteomic profiling of paraffin-embedded samples identifies metaplasia-specific and early-stage gastric cancer biomarkers. Am J Pathol (2012) 0.92
Mesenchymal hamartomas of the liver: comparison of clinicopathologic features between cystic and solid forms. J Korean Med Sci (2006) 0.92
Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas. Hum Pathol (2012) 0.92