Overexpression of clusterin in human hepatocellular carcinoma.

PubWeight™: 1.06‹?› | Rank: Top 10%

🔗 View Article (PMID 15668890)

Published in Hum Pathol on November 01, 2004

Authors

Yun Kyung Kang1, Seong Woo Hong, Hyucksang Lee, Woo Ho Kim

Author Affiliations

1: Department of Pathology, Inje University, Seoul Paik Hospital, Korea.

Articles citing this

Antisense oligonucleotide against clusterin regulates human hepatocellular carcinoma invasion through transcriptional regulation of matrix metalloproteinase-2 and E-cadherin. Int J Mol Sci (2012) 1.52

LC-MS/MS-based serum proteomics for identification of candidate biomarkers for hepatocellular carcinoma. Proteomics (2015) 1.11

Profiling of serum and tissue high abundance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. Proteome Sci (2008) 0.99

Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulum stress induced apoptosis through GRP78. PLoS One (2013) 0.93

Knockdown of clusterin sensitizes pancreatic cancer cells to gemcitabine chemotherapy by ERK1/2 inactivation. J Exp Clin Cancer Res (2012) 0.89

Novel changes in glycosylation of serum Apo-J in patients with hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev (2011) 0.87

Advances in cancer tissue microarray technology: Towards improved understanding and diagnostics. Anal Chim Acta (2006) 0.85

Differential expression of haptoglobin isoforms in chronic active hepatitis, cirrhosis and HCC related to HBV infection. Oncol Lett (2011) 0.84

Clusterin facilitates metastasis by EIF3I/Akt/MMP13 signaling in hepatocellular carcinoma. Oncotarget (2015) 0.84

The application of a three-step serum proteome analysis for the discovery and identification of novel biomarkers of hepatocellular carcinoma. Int J Proteomics (2012) 0.84

Tumor biomarker glycoproteins in the seminal plasma of healthy human males are endogenous ligands for DC-SIGN. Mol Cell Proteomics (2011) 0.83

The hepatic transcriptome in human liver disease. Comp Hepatol (2006) 0.82

Clusterin immunoexpression and its clinical significance in patients with non-small cell lung cancer. Lung (2010) 0.80

O Labeling for a Quantitative Proteomic Analysis of Glycoproteins in Hepatocellular Carcinoma. Clin Proteomics (2008) 0.78

Downregulating sCLU enhances the sensitivity of hepatocellular carcinoma cells to gemcitabine by activating the intrinsic apoptosis pathway. Dig Dis Sci (2014) 0.76

Screening and cloning for proteins transactivated by the PS1TP5 protein of hepatitis B virus: a suppression subtractive hybridization study. World J Gastroenterol (2007) 0.75

Effects of down-regulation of clusterin by small interference RNA on human acute myeloid leukemia cells. Int J Clin Exp Med (2015) 0.75

Therapeutic Strategies and New Intervention Points in Chronic Hepatitis Delta Virus Infection. Int J Mol Sci (2015) 0.75

Hepatitis D and hepatocellular carcinoma. World J Hepatol (2015) 0.75

Clusterin: Review of research progress and looking ahead to direction in hepatocellular carcinoma. World J Gastroenterol (2015) 0.75

Articles by these authors

(truncated to the top 100)

Stage migration effect on survival in gastric cancer surgery with extended lymphadenectomy: the reappraisal of positive lymph node ratio as a proper N-staging. Ann Surg (2012) 1.96

Multicenter analysis of clinicopathologic features of intraductal papillary mucinous tumor of the pancreas: is it possible to predict the malignancy before surgery? Ann Surg Oncol (2005) 1.95

Tumour suppressor gene expression correlates with gastric cancer prognosis. J Pathol (2003) 1.86

Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. Am J Pathol (2002) 1.82

Current Trends of the Incidence and Pathological Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) in Korea 2000-2009: Multicenter Study. Cancer Res Treat (2012) 1.76

Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. Gastroenterology (2010) 1.64

Prognostic importance of epithelial-mesenchymal transition-related protein expression in gastric carcinoma. Histopathology (2009) 1.64

Synchronous and metachronous cancers in patients with gastric cancer. J Surg Oncol (2008) 1.62

Low Ki-67 proliferation index is an indicator of poor prognosis in gastric cancer. J Surg Oncol (2010) 1.58

Analysis of the lymphatic stream to predict sentinel nodes in gastric cancer patients. Ann Surg Oncol (2013) 1.53

Molecular pathology of gastric carcinoma. Pathobiology (2011) 1.49

Promoter methylation and silencing of PTEN in gastric carcinoma. Lab Invest (2002) 1.47

Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis. Cancer Res (2008) 1.45

Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary. Hum Pathol (2002) 1.41

E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis. Nat Med (2006) 1.40

Prognostic significance of Ki-67 expression in rectal carcinoid tumors. Korean J Gastroenterol (2013) 1.39

Evaluation of HER-2 gene status in gastric carcinoma using immunohistochemistry, fluorescence in situ hybridization, and real-time quantitative polymerase chain reaction. Hum Pathol (2007) 1.36

Protein expression profiling and molecular classification of gastric cancer by the tissue array method. Clin Cancer Res (2007) 1.35

Expression of mucins and cytokeratins in primary carcinomas of the digestive system. Mod Pathol (2003) 1.35

Epstein-barr virus-positive gastric carcinoma has a distinct protein expression profile in comparison with epstein-barr virus-negative carcinoma. Clin Cancer Res (2004) 1.33

Clinicopathological analysis for recurrence of early gastric cancer. Jpn J Clin Oncol (2003) 1.31

Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma. Am J Pathol (2002) 1.29

Heterogeneous amplification of ERBB2 in primary lesions is responsible for the discordant ERBB2 status of primary and metastatic lesions in gastric carcinoma. Histopathology (2011) 1.29

Clinicopathologic analysis of early ampullary cancers with a focus on the feasibility of ampullectomy. Ann Surg (2005) 1.26

RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma. Cancer Biol Ther (2011) 1.26

Diagnostic accuracy of T and N stages with endoscopy, stomach protocol CT, and endoscopic ultrasonography in early gastric cancer. J Surg Oncol (2009) 1.26

Focal peliosis hepatis as a mimicker of hepatic tumors: radiological-pathological correlation. J Comput Assist Tomogr (2007) 1.25

Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer. Hum Pathol (2011) 1.25

Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death. Exp Mol Med (2007) 1.24

The tissue microarray object model: a data model for storage, analysis, and exchange of tissue microarray experimental data. Arch Pathol Lab Med (2006) 1.22

Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res (2005) 1.22

Clinical practice guideline for accurate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea. J Korean Med Sci (2010) 1.21

Akt/PKB activation in gastric carcinomas correlates with clinicopathologic variables and prognosis. APMIS (2003) 1.21

Diagnosis of gastric epithelial neoplasia: Dilemma for Korean pathologists. World J Gastroenterol (2011) 1.20

Clinical significance of preoperative inflammatory parameters in gastric cancer patients. J Gastric Cancer (2013) 1.19

DNA methylation in peripheral blood: a potential biomarker for cancer molecular epidemiology. J Epidemiol (2012) 1.19

Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. Cancer Sci (2003) 1.18

The role of PET/CT in detection of gastric cancer recurrence. BMC Cancer (2009) 1.16

Distinct clinical features and outcomes of gastric cancers with microsatellite instability. Mod Pathol (2002) 1.16

Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res (2007) 1.15

A naturally derived gastric cancer cell line shows latency I Epstein-Barr virus infection closely resembling EBV-associated gastric cancer. Virology (2004) 1.15

Clinical practice guideline for accurate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea. Cancer Res Treat (2012) 1.14

Aberrant methylation of p14ARF gene correlates with poor survival in osteosarcoma. Clin Orthop Relat Res (2006) 1.12

Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. Eur J Cancer (2009) 1.12

Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice. Cancer Res (2005) 1.12

Risk factors of residual or recurrent tumor in patients with a tumor-positive resection margin after endoscopic resection of early gastric cancer. Surg Endosc (2012) 1.12

Clinical outcome of pylorus-preserving gastrectomy in gastric cancer in comparison with conventional distal gastrectomy with Billroth I anastomosis. World J Surg (2008) 1.11

Expressions of HSP70 and HSP27 in hepatocellular carcinoma. J Korean Med Sci (2005) 1.11

Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells. Cancer Res (2008) 1.11

Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. BMC Cancer (2008) 1.11

Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach. Cancer (2005) 1.11

Expression of G1-S modulators (p53, p16, p27, cyclin D1, Rb) and Smad4/Dpc4 in intrahepatic cholangiocarcinoma. Hum Pathol (2002) 1.11

Identification and characterization of a novel cancer/testis antigen gene CAGE. Biochem Biophys Res Commun (2002) 1.08

Current trends in the epidemiological and pathological characteristics of gastrointestinal stromal tumors in Korea, 2003-2004. J Korean Med Sci (2010) 1.08

Fibroblast growth factor receptor 2 gene amplification status and its clinicopathologic significance in gastric carcinoma. Hum Pathol (2012) 1.08

Mucinous gastric carcinomas: clinicopathologic and molecular analyses. Cancer (2009) 1.04

Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer. J Mol Diagn (2012) 1.03

Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer. Hum Pathol (2010) 1.03

Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma. Oncol Rep (2009) 1.01

Prognostic significance of CD24 expression in gastric carcinoma. Cancer Res Treat (2004) 1.01

A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer. Carcinogenesis (2007) 1.01

Subclassification of pT2 gastric adenocarcinoma according to depth of invasion (pT2a vs pT2b) and lymph node status (pN). Surgery (2007) 1.00

Prognostic significance of glutathione peroxidase 1 (GPX1) down-regulation and correlation with aberrant promoter methylation in human gastric cancer. Anticancer Res (2012) 0.99

Distribution of LGR5+ cells and associated implications during the early stage of gastric tumorigenesis. PLoS One (2013) 0.99

Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays. Cancer Lett (2002) 0.99

Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir. Cancer Lett (2006) 0.99

Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance. Clin Cancer Res (2005) 0.98

The value of palliative gastrectomy in gastric cancer with distant metastasis. Ann Surg Oncol (2011) 0.98

Up-regulated expression of sulfatases (SULF1 and SULF2) as prognostic and metastasis predictive markers in human gastric cancer. J Pathol (2012) 0.98

Epstein-Barr virus and microsatellite instability in gastric carcinogenesis. J Pathol (2003) 0.98

Clinical significance of high focal adhesion kinase gene copy number and overexpression in invasive breast cancer. Breast Cancer Res Treat (2010) 0.98

Comparative analysis of protein expressions in primary and metastatic gastric carcinomas. Hum Pathol (2008) 0.97

Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer. Int J Oncol (2007) 0.97

Fatty acid-CoA ligase 4 is overexpressed in human hepatocellular carcinoma. Cancer Sci (2003) 0.97

Prognostic significance of microsatellite instability in sporadic colorectal cancer. Int J Colorectal Dis (2004) 0.96

Meta- and gene set analysis of stomach cancer gene expression data. Mol Cells (2007) 0.96

LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients. Breast Cancer Res Treat (2013) 0.95

Increased intratumoral lymphatic vessel density correlates with lymph node metastasis in early gastric carcinoma. Ann Surg Oncol (2009) 0.95

Cytokeratin expression profile in gastric carcinomas. Hum Pathol (2004) 0.94

The combined expression of metaplasia biomarkers predicts the prognosis of gastric cancer. Ann Surg Oncol (2011) 0.94

Constitutive activation of signal transducers and activators of transcription 3 correlates with better prognosis, cell proliferation and hypoxia-inducible factor-1α in human gastric cancer. Pathobiology (2011) 0.94

Epstein-Barr virus in human malignancy: a special reference to Epstein-Barr virus associated gastric carcinoma. Cancer Res Treat (2005) 0.94

Mutation and altered expression of beta-catenin during gallbladder carcinogenesis. Am J Surg Pathol (2002) 0.94

COX2 overexpression is a prognostic marker for Stage III breast cancer. Breast Cancer Res Treat (2011) 0.94

Effects of ERCC1 expression in peripheral blood on the risk of head and neck cancer. Eur J Cancer Prev (2006) 0.93

Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression. Cancer Lett (2006) 0.93

Manganese superoxide dismutase expression correlates with a poor prognosis in gastric cancer. Pathobiology (2003) 0.93

Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic marker. Int J Cancer (2013) 0.93

Clinicopathological characteristics, microsatellite instability, and expression of mucin core proteins and p53 in colorectal mucinous adenocarcinomas in relation to location. Virchows Arch (2006) 0.93

Hereditary nonpolyposis colorectal cancer in endometrial cancer patients. Int J Cancer (2008) 0.92

Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer. Mod Pathol (2007) 0.92

Proteomic profiling of paraffin-embedded samples identifies metaplasia-specific and early-stage gastric cancer biomarkers. Am J Pathol (2012) 0.92

Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas. Hum Pathol (2012) 0.92

Prognostic significance of Bcl-2 and p53 expression in gastric cancer. Int J Colorectal Dis (2003) 0.92

Outcomes of minimally invasive surgery for early gastric cancer are comparable with those for open surgery: analysis of 1,013 minimally invasive surgeries at a single institution. Surg Endosc (2013) 0.91

Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers. Pathol Res Pract (2005) 0.91

SERPINE1 intron polymorphisms affecting gene expression are associated with diffuse-type gastric cancer susceptibility. Cancer (2010) 0.91

The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway. Gastric Cancer (2013) 0.91

Perigastric tumor deposits in primary gastric cancer: implications for patient prognosis and staging. Ann Surg Oncol (2012) 0.91

Expression of gastrin and its receptor in human gastric cancer tissues. J Cancer Res Clin Oncol (2005) 0.91