Published in Lancet on September 28, 2002
Variation in the human immune system is largely driven by non-heritable influences. Cell (2015) 3.07
Hepatitis E and pregnancy: understanding the pathogenesis. Liver Int (2008) 2.56
HLA and infectious diseases. Clin Microbiol Rev (2009) 2.35
Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics. Hum Genet (2008) 1.57
Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence. Proc Natl Acad Sci U S A (2006) 1.41
Application of pharmacogenomics to vaccines. Pharmacogenomics (2009) 1.30
A common HLA-DPA1 variant is a major determinant of hepatitis B virus clearance in Han Chinese. J Infect Dis (2011) 1.17
Systems vaccinology: probing humanity's diverse immune systems with vaccines. Proc Natl Acad Sci U S A (2014) 1.16
Host genetic factors and vaccine-induced immunity to hepatitis B virus infection. PLoS One (2008) 1.16
Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine (2011) 0.99
Vaccinomics: current findings, challenges and novel approaches for vaccine development. AAPS J (2011) 0.93
A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM). J Biomed Biotechnol (2010) 0.92
Searching for the human genetic factors standing in the way of universally effective vaccines. Philos Trans R Soc Lond B Biol Sci (2015) 0.90
Selective suppression of NF-kBp65 in hepatitis virus-infected pregnant women manifesting severe liver damage and high mortality. Mol Med (2007) 0.89
The genetic regulation of infant immune responses to vaccination. Front Immunol (2015) 0.89
Analysis of mitochondrial length heteroplasmy in monozygous and non-monozygous siblings. Int J Legal Med (2008) 0.89
Non-responsiveness to hepatitis B surface antigen vaccines is not caused by defective antigen presentation or a lack of B7 co-stimulation. Clin Exp Immunol (2005) 0.88
Host susceptibility to persistent hepatitis B virus infection. World J Gastroenterol (2006) 0.88
Utilizing population variation, vaccination, and systems biology to study human immunology. Trends Immunol (2015) 0.88
Clear and independent associations of several HLA-DRB1 alleles with differential antibody responses to hepatitis B vaccination in youth. Hum Genet (2009) 0.87
Association between single-nucleotide polymorphisms and early spontaneous hepatitis B virus e antigen seroconversion in children. BMC Res Notes (2014) 0.86
Hepatitis B surface antigen presentation and HLA-DRB1*- lessons from twins and peptide binding studies. Clin Exp Immunol (2005) 0.86
Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development. Sci Rep (2015) 0.84
Polymorphisms in Toll-like receptor genes influence antibody responses to cytomegalovirus glycoprotein B vaccine. BMC Res Notes (2012) 0.83
CD3Z genetic polymorphism in immune response to hepatitis B vaccination in two independent Chinese populations. PLoS One (2012) 0.82
HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection. World J Gastroenterol (2013) 0.81
Cofactors that may influence vaccine responses. Curr Opin HIV AIDS (2010) 0.80
Factors influencing immunologic response to hepatitis B vaccine in adults. Sci Rep (2016) 0.79
Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology. Braz J Med Biol Res (2011) 0.79
Stochastic humoral immunity to Bacillus anthracis protective antigen: identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization. Vaccine (2013) 0.78
Immunologic hypo- or non-responder in natural dengue virus infection. J Biomed Sci (2013) 0.77
Granulocyte colony-stimulating factor as a novel adjunct to improve hepatitis B vaccination. World J Hepatol (2010) 0.76
Mannose-binding lectin and ficolin-2 do not influence humoral immune response to hepatitis B vaccine. Vaccine (2014) 0.76
Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination. Nat Commun (2016) 0.75
Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting 'Tefera Hailu' memorial hospital, Sekota, Northern Ethiopia. BMC Infect Dis (2016) 0.75
Genetics and vaccines in the era of personalized medicine. Curr Genomics (2015) 0.75
Construction of exogenous multiple epitopes of helper T lymphocytes and DNA immunization of its chimeric plasmid with HBV pre-S2/S gene. World J Gastroenterol (2004) 0.75
N. meningitidis and TLR Polymorphisms: A Fascinating Immunomodulatory Network. Vaccines (Basel) (2016) 0.75
The personal touch: strategies toward personalized vaccines and predicting immune responses to them. Expert Rev Vaccines (2014) 0.75
Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection. Pathog Immun (2017) 0.75
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet (2012) 5.28
Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer. J Clin Oncol (2005) 4.35
A genome-wide scan for common alleles affecting risk for autism. Hum Mol Genet (2010) 3.42
Silent and apparent cerebral embolism after retrograde catheterisation of the aortic valve in valvular stenosis: a prospective, randomised study. Lancet (2003) 2.86
Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. PLoS Genet (2012) 2.65
A multiplex assay with 52 single nucleotide polymorphisms for human identification. Electrophoresis (2006) 2.59
Genome-wide analysis of copy number variants in attention deficit hyperactivity disorder: the role of rare variants and duplications at 15q13.3. Am J Psychiatry (2012) 2.48
Individual common variants exert weak effects on the risk for autism spectrum disorderspi. Hum Mol Genet (2012) 2.46
SNP-based analysis of genetic substructure in the German population. Hum Hered (2006) 2.21
Systemic complement activation in age-related macular degeneration. PLoS One (2008) 2.18
Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. J Clin Oncol (2003) 2.14
The "diffuse-trickling" fundus autofluorescence phenotype in geographic atrophy. Invest Ophthalmol Vis Sci (2014) 2.06
Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study. Med Microbiol Immunol (2007) 2.04
DNA-based prediction of human externally visible characteristics in forensics: motivations, scientific challenges, and ethical considerations. Forensic Sci Int Genet (2009) 1.98
Risk and fate of cerebral embolism after transfemoral aortic valve implantation: a prospective pilot study with diffusion-weighted magnetic resonance imaging. J Am Coll Cardiol (2010) 1.98
Safety of brain 3-T MR imaging with transmit-receive head coil in patients with cardiac pacemakers: pilot prospective study with 51 examinations. Radiology (2008) 1.91
Tidal recruitment assessed by electrical impedance tomography and computed tomography in a porcine model of lung injury*. Crit Care Med (2012) 1.84
C4A deficiency and nonresponse to hepatitis B vaccination. J Hepatol (2002) 1.74
Prediction of necrosis after chemotherapy of advanced germ cell tumors: results of a prospective multicenter trial of the German Testicular Cancer Study Group. J Urol (2004) 1.68
Clinical and immunologic responses to multiple doses of IMVAMUNE (Modified Vaccinia Ankara) followed by Dryvax challenge. Vaccine (2007) 1.67
Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder. Nat Genet (2011) 1.63
The evolution of DNA databases--recommendations for new European STR loci. Forensic Sci Int (2005) 1.60
Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B-related disease. Hepatology (2003) 1.59
Paternity Testing Commission of the International Society of Forensic Genetics: recommendations on genetic investigations in paternity cases. Forensic Sci Int (2002) 1.59
Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology (2007) 1.56
Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis. Hum Genet (2005) 1.47
ISFG: Recommendations on biostatistics in paternity testing. Forensic Sci Int Genet (2007) 1.46
Comparison of MELD, Child-Pugh, and Emory model for the prediction of survival in patients undergoing transjugular intrahepatic portosystemic shunting. Am J Gastroenterol (2003) 1.46
Transit time flow measurement in on-pump and off-pump coronary artery surgery. J Thorac Cardiovasc Surg (2003) 1.45
Risk factors for relapse in clinical stage I nonseminomatous testicular germ cell tumors: results of the German Testicular Cancer Study Group Trial. J Clin Oncol (2003) 1.44
A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Hum Genet (2011) 1.43
Efficacy of 5-week doxycycline treatment on adult Onchocerca volvulus. Parasitol Res (2008) 1.42
Incidence of blindness and severe visual impairment in Germany: projections for 2030. Invest Ophthalmol Vis Sci (2011) 1.36
A randomized, double-blind, dose-finding Phase II study to evaluate immunogenicity and safety of the third generation smallpox vaccine candidate IMVAMUNE. Vaccine (2009) 1.36
Prevalence and causes of registered blindness in the largest federal state of Germany. Br J Ophthalmol (2011) 1.36
Coronary MR angiography at 3.0 T versus that at 1.5 T: initial results in patients suspected of having coronary artery disease. Radiology (2005) 1.35
Publication of population data for forensic purposes. Forensic Sci Int Genet (2010) 1.31
Safety, feasibility, and diagnostic value of cardiac magnetic resonance imaging in patients with cardiac pacemakers and implantable cardioverters/defibrillators at 1.5 T. Am Heart J (2011) 1.30
A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment. Psychiatry Res (2007) 1.29
Oligodendroglial tumors: refinement of candidate regions on chromosome arm 1p and correlation of 1p/19q status with survival. Brain Pathol (2004) 1.29
The spectrum of long-term epilepsy-associated tumors: long-term seizure and tumor outcome and neurosurgical aspects. Epilepsia (2003) 1.26
Treatment of choroidal neovascularization due to angioid streaks: a comprehensive review. Retina (2013) 1.24
Supratentorial gangliogliomas: histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years. Cancer (2004) 1.23
Reading performance is reduced by parafoveal scotomas in patients with macular telangiectasia type 2. Invest Ophthalmol Vis Sci (2008) 1.23
Empathy in children with autism and conduct disorder: group-specific profiles and developmental aspects. J Child Psychol Psychiatry (2011) 1.23
Therapeutic vaccination of HIV-1-infected patients on HAART with a recombinant HIV-1 nef-expressing MVA: safety, immunogenicity and influence on viral load during treatment interruption. Antivir Ther (2005) 1.22
A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proc Natl Acad Sci U S A (2012) 1.21
Repeated bone-targeted therapy for hormone-refractory prostate carcinoma: tandomized phase II trial with the new, high-energy radiopharmaceutical rhenium-188 hydroxyethylidenediphosphonate. J Clin Oncol (2003) 1.19
Qigong exercise for the symptoms of Parkinson's disease: a randomized, controlled pilot study. Mov Disord (2006) 1.19
Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients. Clin Cancer Res (2009) 1.19
Introduction of an single nucleodite polymorphism-based "Major Y-chromosome haplogroup typing kit" suitable for predicting the geographical origin of male lineages. Electrophoresis (2005) 1.18
How to model a complex trait. 2. Analysis with two disease loci. Hum Hered (2003) 1.16
Prognostic factors and outcome after different types of resection for temporal lobe epilepsy. J Neurosurg (2002) 1.14
New multiplexes for Europe-amendments and clarification of strategic development. Forensic Sci Int (2006) 1.13
Evaluation of cumulative effects of MR imaging on pacemaker systems at 1.5 Tesla. Pacing Clin Electrophysiol (2009) 1.13
Doxycycline improves filarial lymphedema independent of active filarial infection: a randomized controlled trial. Clin Infect Dis (2012) 1.12
Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women. Int J Neuropsychopharmacol (2004) 1.12
Forensic validation of the SNPforID 52-plex assay. Forensic Sci Int Genet (2007) 1.11
Impact of genotype and morphology on the prognosis of glioblastoma. J Neuropathol Exp Neurol (2002) 1.11
Behavioral comorbidity differs in subtypes of enuresis and urinary incontinence. J Urol (2007) 1.07
Impaired gamma-band activity during perceptual organization in adults with autism spectrum disorders: evidence for dysfunctional network activity in frontal-posterior cortices. J Neurosci (2012) 1.07
A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder. Am J Med Genet B Neuropsychiatr Genet (2010) 1.06
Safety, immunogenicity, and surrogate markers of clinical efficacy for modified vaccinia Ankara as a smallpox vaccine in HIV-infected subjects. J Infect Dis (2012) 1.06
DTNBP1 (dysbindin) gene variants modulate prefrontal brain function in healthy individuals. Neuropsychopharmacology (2006) 1.06
Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans. Arch Gen Psychiatry (2009) 1.06
Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema. J Allergy Clin Immunol (2005) 1.04
GH/IGF-I regulation in obesity--mechanisms and practical consequences in children and adults. Horm Res Paediatr (2010) 1.04
New guidelines for the publication of genetic population data. Forensic Sci Int Genet (2013) 1.03
Anticancer effects of niclosamide in human glioblastoma. Clin Cancer Res (2013) 1.03
Preparation of degraded human DNA under controlled conditions. Forensic Sci Int (2004) 1.02
A functional polymorphism in the IL-10 promoter influences the response after vaccination with HBsAg and hepatitis A. Hepatology (2005) 1.02
Acute myocarditis: multiparametric cardiac MR imaging. Radiology (2014) 1.01
Changes of basic bone turnover parameters in short-term and long-term patients with spinal cord injury. Eur Spine J (2006) 1.00
Noncancerous PTGS2 DNA fragments of apoptotic origin in sera of prostate cancer patients qualify as diagnostic and prognostic indicators. Int J Cancer (2008) 1.00
Comparison of curet and paper point sampling of subgingival bacteria as analyzed by real-time polymerase chain reaction. J Periodontol (2007) 0.98
STR genotyping and mtDNA sequencing of latent fingerprint on paper. Forensic Sci Int (2003) 0.98
Association of a functional 1019C>G 5-HT1A receptor gene polymorphism with panic disorder with agoraphobia. Int J Neuropsychopharmacol (2004) 0.97
A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet (2008) 0.97
Early relapses in primary CNS lymphoma after response to polychemotherapy without intraventricular treatment: results of a phase II study. J Neurooncol (2008) 0.97
Familial aggregation of alopecia areata. J Am Acad Dermatol (2006) 0.96
Familial occurrence of systemic mast cell activation disease. PLoS One (2013) 0.95
'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate. Bioinformatics (2012) 0.95
Early complete response during chemotherapy predicts favorable outcome in patients with primary CNS lymphoma. Neuro Oncol (2010) 0.95
Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci. Hum Mol Genet (2011) 0.95
High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol (1985) (2011) 0.95
Neuromotor development in nocturnal enuresis. Dev Med Child Neurol (2006) 0.94
Development of a pentaplex X-chromosomal short tandem repeat typing system and population genetic studies. Forensic Sci Int (2004) 0.94
Norepinephrine transporter (NET) promoter and 5'-UTR polymorphisms: association analysis in panic disorder. Neurosci Lett (2004) 0.93
Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors. Int J Cancer (2007) 0.93
Feasible and successful: genome-wide interaction analysis involving all 1.9 x 10(11) pair-wise interaction tests. Hum Hered (2010) 0.93
Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J Immunol (2011) 0.93