Published in Hum Hered on September 21, 2006
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry (2007) 6.72
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet (2008) 5.23
Association of FOXO3A variation with human longevity confirmed in German centenarians. Proc Natl Acad Sci U S A (2009) 4.02
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46
Tobacco smoking leads to extensive genome-wide changes in DNA methylation. PLoS One (2013) 3.19
Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe. PLoS One (2008) 3.09
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet (2011) 2.68
Designing candidate gene and genome-wide case-control association studies. Nat Protoc (2007) 2.42
Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. PLoS Genet (2009) 1.80
Systematic association mapping identifies NELL1 as a novel IBD disease gene. PLoS One (2007) 1.57
Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor. Neurology (2012) 1.41
Identifying modifier genes of monogenic disease: strategies and difficulties. Hum Genet (2008) 1.13
Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. Psychopharmacology (Berl) (2006) 1.09
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet (2013) 1.06
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA. Int J Obes (Lond) (2010) 1.04
Population substructure in Finland and Sweden revealed by the use of spatial coordinates and a small number of unlinked autosomal SNPs. BMC Genet (2008) 1.02
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Arch Gen Psychiatry (2010) 1.02
HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy. Genome Res (2008) 1.00
Swedish population substructure revealed by genome-wide single nucleotide polymorphism data. PLoS One (2011) 0.97
Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays. BMC Genet (2011) 0.91
Characterization of whole-genome autosomal differences of DNA methylation between men and women. Epigenetics Chromatin (2015) 0.90
Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years. BMC Cancer (2008) 0.89
Genome-wide investigation of gene-environment interactions in colorectal cancer. Hum Genet (2012) 0.89
A genomewide comparison of population structure at STRPs and nearby SNPs in humans. Mol Biol Evol (2009) 0.89
Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry. BMC Med Genet (2009) 0.86
Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy. Neurobiol Dis (2007) 0.86
Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene. BMC Cancer (2008) 0.84
Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study. Genet Epidemiol (2015) 0.81
First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study. J Epidemiol Community Health (2010) 0.80
Investigation of complement component C4 copy number variation in human longevity. PLoS One (2014) 0.80
Genetic population structure analysis in New Hampshire reveals Eastern European ancestry. PLoS One (2009) 0.79
Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups. BMC Med Genet (2009) 0.79
SNPs and Hox gene mapping in Ciona intestinalis. BMC Genomics (2008) 0.78
Association between DNA Methylation in Whole Blood and Measures of Glucose Metabolism: KORA F4 Study. PLoS One (2016) 0.77
The genetic variation in monocarboxylic acid transporter 2 (MCT2) has functional and clinical relevance with male infertility. Asian J Androl (2014) 0.77
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Sci Adv (2016) 0.77
NMR based metabonomics study on celiac disease in the blood serum. Gastroenterol Hepatol Bed Bench (2013) 0.76
Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study. BMC Gastroenterol (2016) 0.75
Genetic Geostatistical Framework for Spatial Analysis of Fine-Scale Genetic Heterogeneity in Modern Populations: Results from the KORA Study. Int J Genomics (2015) 0.75
The more the merrier? How a few SNPs predict pigmentation phenotypes in the Northern German population. Eur J Hum Genet (2015) 0.75
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2006) 15.14
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron (2004) 14.35
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature (2012) 13.61
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Human Gene Mutation Database (HGMD): 2003 update. Hum Mutat (2003) 12.88
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron (2011) 10.61
Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol (2005) 10.16
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet (2009) 9.45
Testing for an unusual distribution of rare variants. PLoS Genet (2011) 9.28
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89