Published in JAMA on October 21, 2002
Future cardiovascular disease in china: markov model and risk factor scenario projections from the coronary heart disease policy model-china. Circ Cardiovasc Qual Outcomes (2010) 2.63
Leptin and cardiovascular disease: response to therapeutic interventions. Circulation (2008) 1.58
Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care (2009) 1.46
Toll-like receptor 4 modulates skeletal muscle substrate metabolism. Am J Physiol Endocrinol Metab (2010) 1.45
Preeclampsia and future cardiovascular risk: formal risk factor or failed stress test? Ther Adv Cardiovasc Dis (2008) 1.38
Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study. J Clin Oncol (2009) 1.31
Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the Health, Aging and Body Composition Study. Diabetes Metab Res Rev (2009) 1.28
Oxidative risk for atherothrombotic cardiovascular disease. Free Radic Biol Med (2009) 1.24
Oxidative stress biomarkers and lifestyles in Japanese healthy people. J Clin Biochem Nutr (2009) 1.18
Optimal body weight for health and longevity: bridging basic, clinical, and population research. Aging Cell (2014) 1.16
The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level. Free Radic Biol Med (2008) 1.15
Maternal antioxidant supplementation prevents adiposity in the offspring of Western diet-fed rats. Diabetes (2010) 1.13
Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective. Int J Endocrinol (2011) 1.12
Platelet counts and platelet activation markers in obese subjects. Mediators Inflamm (2008) 1.10
F2-isoprostanes as an indicator and risk factor for coronary heart disease. Free Radic Biol Med (2010) 1.04
Long-term effects of caloric restriction or exercise on DNA and RNA oxidation levels in white blood cells and urine in humans. Rejuvenation Res (2008) 1.02
Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. J Gerontol A Biol Sci Med Sci (2012) 1.00
Body composition and serum prostate-specific antigen: review and findings from Flint Men's Health Study. Urology (2008) 0.99
Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. Mol Nutr Food Res (2013) 0.96
The levels of soluble CD40 ligand and C-reactive protein in normal weight, overweight and obese people. Clin Med Res (2010) 0.96
Inhibition of thromboxane A2-induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of the inositol trisphosphate pathway. J Pharmacol Exp Ther (2009) 0.93
Differences in systemic oxidative stress based on race and the metabolic syndrome: the Morehouse and Emory Team up to Eliminate Health Disparities (META-Health) study. Metab Syndr Relat Disord (2012) 0.93
Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome. Hypertension (2012) 0.92
Impact of ramadan intermittent fasting on oxidative stress measured by urinary 15-f(2t)-isoprostane. J Nutr Metab (2012) 0.90
Adipocytokines in atherothrombosis: focus on platelets and vascular smooth muscle cells. Mediators Inflamm (2010) 0.90
Relationship of the dietary phytochemical index to weight gain, oxidative stress and inflammation in overweight young adults. J Hum Nutr Diet (2009) 0.90
Is all fat the same? The role of fat in the pathogenesis of the metabolic syndrome and type 2 diabetes mellitus. Surgery (2006) 0.90
Clinical determinants of aspirin resistance in diabetes. Diabetes Res Clin Pract (2010) 0.90
Maternal obesity during pregnancy and cardiovascular development and disease in the offspring. Eur J Epidemiol (2015) 0.89
Oxidative stress, antioxidants, and vascular damage. Br J Clin Pharmacol (2006) 0.89
Dietary Weight Loss, Exercise, and Oxidative Stress in Postmenopausal Women: A Randomized Controlled Trial. Cancer Prev Res (Phila) (2016) 0.88
Should antioxidant status be considered in interventional trials with antioxidants? Heart (2004) 0.87
Etiopathogenetic mechanisms of pulmonary hypertension in sleep-related breathing disorders. Pulm Med (2012) 0.87
Aspirin for primary prevention of cardiovascular disease in diabetes mellitus. Nat Rev Endocrinol (2010) 0.86
No effect of cigarette smoking dose on oxidized plasma proteins. Environ Res (2007) 0.86
Physical functioning related to C-reactive protein and fibrinogen levels in mid-life women. Exp Gerontol (2009) 0.85
Topographical body fat distribution links to amino acid and lipid metabolism in healthy obese women [corrected]. PLoS One (2013) 0.85
Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertil Steril (2013) 0.83
Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. J Am Heart Assoc (2013) 0.83
Exercise and diet-induced weight loss attenuates oxidative stress related-coronary vasoconstriction in obese adolescents. Eur J Appl Physiol (2012) 0.83
Association of systemic oxidative stress with suppressed serum IgG to commensal oral biofilm and modulation by periodontal infection. Antioxid Redox Signal (2009) 0.83
Younger age, higher body mass index and lower adiponectin concentration predict higher serum thromboxane B2 level in aspirin-treated patients with type 2 diabetes: an observational study. Cardiovasc Diabetol (2014) 0.82
Effects of obesity and weight loss on soluble CD40L levels. JAMA (2003) 0.82
Association of serum paraoxonase enzyme activity and oxidative stress markers with dyslipidemia in obese adolescents. Indian J Endocrinol Metab (2014) 0.81
Impact of body mass index on clinical outcome in patients with acute coronary syndromes treated with percutaneous coronary intervention. Heart Vessels (2010) 0.81
Association of oxidative stress, iron, and centralized fat mass in healthy postmenopausal women. J Womens Health (Larchmt) (2009) 0.81
Preeclampsia and the future risk of hypertension: the pregnant evidence. Curr Hypertens Rep (2013) 0.80
Association between increased platelet P-selectin expression and obesity in patients with type 2 diabetes: a BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) substudy. Diabetes Care (2009) 0.80
Effect of modest caloric restriction on oxidative stress in women, a randomized trial. PLoS One (2012) 0.80
Childhood obesity: immune response and nutritional approaches. Front Immunol (2015) 0.79
Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders. Nutrients (2016) 0.79
Sex differences in urinary biomarkers of vascular and endothelial function in HIV-infected persons receiving antiretroviral therapy. Antivir Ther (2011) 0.79
Classifying oxidative stress by F2-isoprostane levels across human diseases: A meta-analysis. Redox Biol (2017) 0.79
Alteration of antioxidant defense status precedes humoral immune response abnormalities in macrosomia. Med Sci Monit (2011) 0.79
The prothrombotic tendency in metabolic syndrome: focus on the potential mechanisms involved in impaired haemostasis and fibrinolytic balance. Scientifica (Cairo) (2012) 0.79
Severe but Not Moderate Vitamin B12 Deficiency Impairs Lipid Profile, Induces Adiposity, and Leads to Adverse Gestational Outcome in Female C57BL/6 Mice. Front Nutr (2016) 0.79
Increased visceral adipose tissue as a potential risk factor in patients with embolic stroke of undetermined source (ESUS). PLoS One (2015) 0.79
Influence of lifestyle modifications on age-related free radical injury to brain. JAMA Neurol (2014) 0.78
Platelet counts and liver enzymes after bariatric surgery. J Obes (2013) 0.78
Thromboxane synthase deficiency improves insulin action and attenuates adipose tissue fibrosis. Am J Physiol Endocrinol Metab (2015) 0.78
Evaluation of serum neopterin, high-sensitivity C-reactive protein and thiobarbituric acid reactive substances in Egyptian patients with acute coronary syndromes. Exp Clin Cardiol (2005) 0.78
Higher serum iron is associated with increased oxidant stress in HIV-infected men. J Acquir Immune Defic Syndr (2013) 0.78
The effects of treatment with liraglutide on atherothrombotic risk in obese young women with polycystic ovary syndrome and controls. BMC Endocr Disord (2015) 0.78
Maternal inflammation during pregnancy and childhood adiposity. Obesity (Silver Spring) (2016) 0.77
Effect of glucose or fat challenge on aspirin resistance in diabetes. Int J Endocrinol (2011) 0.77
Suboptimal inhibition of platelet cyclooxygenase 1 by aspirin in systemic lupus erythematosus: association with metabolic syndrome. Arthritis Care Res (Hoboken) (2014) 0.77
Ethanol Extract of Persimmon Tree Leaves Improves Blood Circulation and Lipid Metabolism in Rats Fed a High-Fat Diet. J Med Food (2015) 0.76
Associations between arterial stiffness and platelet activation in normotensive overweight and obese young adults. Clin Exp Hypertens (2013) 0.76
Relationship between obesity and serum reactive oxygen metabolites in adolescents. Environ Health Prev Med (2013) 0.76
Plasma fibronectin concentration in obese/overweight pregnant women: a possible risk factor for preeclampsia. Indian J Clin Biochem (2011) 0.75
Urinary Malondialdehyde Is Associated with Visceral Abdominal Obesity in Middle-Aged Men. Mediators Inflamm (2015) 0.75
Insulin resistance in Alzheimer's disease. Transl Res (2016) 0.75
Altered maternal lipid metabolism is associated with higher inflammation in obese women during late pregnancy. Integr Obes Diabetes (2015) 0.75
Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease. Front Aging Neurosci (2017) 0.75
Potential Role of Protein Disulfide Isomerase in Metabolic Syndrome-Derived Platelet Hyperactivity. Oxid Med Cell Longev (2016) 0.75
Pregnancy complications and calculated cardiovascular risk in urban women: do we envisage an association? J Urban Health (2014) 0.75
African Ancestry Gradient Is Associated with Lower Systemic F2-Isoprostane Levels. Oxid Med Cell Longev (2017) 0.75
Better detection of platelet aggregation in patients with metabolic syndrome using epinephrine and ADP. Diabetol Metab Syndr (2014) 0.75
Effect of Dark Chocolate Extracts on Phorbol 12-Myristate 13-Acetate-Induced Oxidative Burst in Leukocytes Isolated by Normo-Weight and Overweight/Obese Subjects. Front Nutr (2017) 0.75
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet (2009) 13.64
Platelet activation and atherothrombosis. N Engl J Med (2007) 6.18
Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. J Natl Cancer Inst (2002) 4.97
Efficacy and safety of low-dose aspirin in polycythemia vera. N Engl J Med (2004) 4.66
The role of aspirin in cancer prevention. Nat Rev Clin Oncol (2012) 2.94
Acute leukemia in polycythemia vera: an analysis of 1638 patients enrolled in a prospective observational study. Blood (2004) 2.64
Vascular and neoplastic risk in a large cohort of patients with polycythemia vera. J Clin Oncol (2005) 2.50
Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". J Am Coll Cardiol (2009) 2.11
Prevalence of peripheral artery disease by abnormal ankle-brachial index in atrial fibrillation: implications for risk and therapy. J Am Coll Cardiol (2013) 2.05
Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis. J Thromb Thrombolysis (2008) 1.96
Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins. Free Radic Biol Med (2007) 1.88
Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. Circulation (2004) 1.88
Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect (2008) 1.83
Aspirin-insensitive thromboxane biosynthesis in essential thrombocythemia is explained by accelerated renewal of the drug target. Blood (2012) 1.78
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. Clin Pharmacol Ther (2006) 1.77
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. Circulation (2002) 1.68
Soluble RAGE in type 2 diabetes: association with oxidative stress. Free Radic Biol Med (2007) 1.67
2015 ESC Guidelines for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-segment Elevation. Rev Esp Cardiol (Engl Ed) (2015) 1.49
VEGF-A gene promoter polymorphisms and microvascular complications in patients with essential hypertension. Clin Biochem (2010) 1.48
A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. JAMA (2004) 1.40
Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus. J Am Coll Cardiol (2003) 1.39
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets. Proc Natl Acad Sci U S A (2002) 1.39
Pentraxin 3 and Platelet Activation in Obese Patients After Gastric Banding. Circ J (2015) 1.39
Lipid peroxidation in diabetes mellitus. Antioxid Redox Signal (2005) 1.37
Selective cyclooxygenase 2 inhibitors, aspirin, and cardiovascular disease: a reappraisal. Arthritis Rheum (2003) 1.32
Association of inflammation markers with impaired insulin sensitivity and coagulative activation in obese healthy women. J Clin Endocrinol Metab (2003) 1.22
Atorvastatin inhibits gp91phox circulating levels in patients with hypercholesterolemia. Arterioscler Thromb Vasc Biol (2009) 1.22
Retracted Balance between PGD synthase and PGE synthase is a major determinant of atherosclerotic plaque instability in humans. Arterioscler Thromb Vasc Biol (2004) 1.22
Hereditary deficiency of gp91(phox) is associated with enhanced arterial dilatation: results of a multicenter study. Circulation (2009) 1.19
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells. Circ Res (2003) 1.17
Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. Circulation (2003) 1.16
Soluble CD40 ligand plasma levels in lung cancer. Clin Cancer Res (2004) 1.15
ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD - summary. Diab Vasc Dis Res (2014) 1.10
Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. Circulation (2002) 1.09
8-Isoprostane in exhaled breath condensate and exercise-induced bronchoconstriction in asthmatic children and adolescents. Chest (2008) 1.09
Effects of inhaled corticosteroids on exhaled leukotrienes and prostanoids in asthmatic children. J Allergy Clin Immunol (2004) 1.07
NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis. Thorax (2011) 1.07
Increased circulating Interleukin-18 levels in centenarians with no signs of vascular disease: another paradox of longevity? Exp Gerontol (2003) 1.07
Increased exhaled 8-isoprostane in childhood asthma. Chest (2003) 1.04
Serum metalloproteinase 9 levels in patients with coronary artery disease: a novel marker of inflammation. J Investig Med (2003) 1.04
Immediate antioxidant and antiplatelet effect of atorvastatin via inhibition of Nox2. Circulation (2012) 1.03
Insulin resistance as a determinant of platelet activation in obese women. J Am Coll Cardiol (2006) 1.00
Cyclooxygenase-2 expression and inhibition in atherothrombosis. Arterioscler Thromb Vasc Biol (2003) 0.99
Diagnostic performance of an electronic nose, fractional exhaled nitric oxide, and lung function testing in asthma. Chest (2010) 0.98
Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice. PLoS One (2009) 0.98
Inflammation, insulin resistance, and obesity. Curr Atheroscler Rep (2004) 0.98
Antiplatelet drugs. Br J Pharmacol (2006) 0.98
Cigarette smoking knowledge and perceptions among students in four Italian medical schools. Nicotine Tob Res (2012) 0.97
Thromboxane-dependent CD40 ligand release in type 2 diabetes mellitus. J Am Coll Cardiol (2005) 0.97
Exhaled 8-isoprostane and prostaglandin E(2) in patients with stable and unstable cystic fibrosis. Free Radic Biol Med (2008) 0.97
Effects of montelukast treatment and withdrawal on fractional exhaled nitric oxide and lung function in children with asthma. Chest (2007) 0.96
Determinants of platelet activation in human essential hypertension. Hypertension (2003) 0.96
Platelet activation, inflammatory mediators and hypercholesterolemia. Curr Vasc Pharmacol (2003) 0.95
Nutraceuticals in diabetes and metabolic syndrome. Cardiovasc Ther (2010) 0.95
New medical licensing examination using computer-based case simulations and standardized patients. Acad Med (2002) 0.93
Endothelial dysfunction in patients with spontaneous venous thromboembolism. Haematologica (2007) 0.93
Determinants of F2-isoprostane biosynthesis and inhibition in man. Chem Phys Lipids (2004) 0.92
A systematic study of brainstem motor nuclei in a mouse model of ALS, the effects of lithium. Neurobiol Dis (2009) 0.92
Atorvastatin inhibits oxidative stress via adiponectin-mediated NADPH oxidase down-regulation in hypercholesterolemic patients. Atherosclerosis (2010) 0.92
Etanercept in the treatment of rheumatoid arthritis: clinical follow-up over one year by ultrasonography. Clin Rheumatol (2007) 0.92
Role of NADPH oxidase in atherosclerosis. Future Cardiol (2009) 0.92
Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis. Biochim Biophys Acta (2012) 0.90
Association between plasma interleukin-18 levels and liver injury in chronic hepatitis C virus infection and non-alcoholic fatty liver disease. Ann Clin Lab Sci (2005) 0.90
Mutations of TP53 induce loss of DNA methylation and amplification of the TROP1 gene. Oncogene (2003) 0.90
Effects of a leukotriene receptor antagonist on exhaled leukotriene E4 and prostanoids in children with asthma. J Allergy Clin Immunol (2006) 0.90
Electronic Nose and Exhaled Breath NMR-based Metabolomics Applications in Airways Disease. Curr Top Med Chem (2016) 0.87
Autonomic dysfunction and microvascular damage in systemic sclerosis. Clin Rheumatol (2007) 0.87
Expression and activity of cyclooxygenase isoforms in skeletal muscles and myocardium of humans and rodents. J Appl Physiol (1985) (2007) 0.87
Vascular endothelial growth factor (VEGF-A) plasma levels in non-small cell lung cancer: relationship with coagulation and platelet activation markers. Thromb Haemost (2003) 0.87
High resolution ultrasonography in detection of bone erosions in patients with hand osteoarthritis. J Rheumatol (2005) 0.86
NOX2 up-regulation is associated with artery dysfunction in patients with peripheral artery disease. Int J Cardiol (2012) 0.86
CD40 ligand and MCP-1 as predictors of cardiovascular events in diabetic patients with stroke. J Atheroscler Thromb (2009) 0.86
Prognostic value of soluble P-selectin levels in colorectal cancer. Int J Cancer (2004) 0.86
Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia. Atherosclerosis (2010) 0.85
Enhanced interleukin-1beta in hypercholesterolemia: effects of simvastatin and low-dose aspirin. Circulation (2003) 0.85
Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. Blood (2008) 0.85
Platelet isoprostane overproduction in diabetic patients treated with aspirin. Diabetes (2012) 0.85