Published in Thorax on November 21, 2011
Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation. ISME J (2014) 1.38
Targeting chelatable iron as a therapeutic modality in Parkinson's disease. Antioxid Redox Signal (2014) 1.29
The upper respiratory tract as a microbial source for pulmonary infections in cystic fibrosis. Parallels from island biogeography. Am J Respir Crit Care Med (2014) 1.00
Candida albicans ethanol stimulates Pseudomonas aeruginosa WspR-controlled biofilm formation as part of a cyclic relationship involving phenazines. PLoS Pathog (2014) 0.93
Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome. ISME J (2015) 0.93
Classification of odorants in the vapor phase using composite features for a portable e-nose system. Sensors (Basel) (2012) 0.91
Developmental regulation of antioxidant enzymes and their impact on neonatal lung disease. Antioxid Redox Signal (2014) 0.87
Increased of exhaled breath condensate neutrophil chemotaxis in acute exacerbation of COPD. Respir Res (2014) 0.84
The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome. Antioxid Redox Signal (2014) 0.84
Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health. Front Microbiol (2016) 0.83
Omics approaches in cystic fibrosis research: a focus on oxylipin profiling in airway secretions. Ann N Y Acad Sci (2012) 0.81
Exhaled breath condensate pH in patients with cystic fibrosis. Inflamm Res (2012) 0.80
A metabolomic perspective on coeliac disease. Autoimmune Dis (2014) 0.80
Multimarker screening of oxidative stress in aging. Oxid Med Cell Longev (2014) 0.78
Breath analysis in pulmonary arterial hypertension. Chest (2014) 0.77
Exhaled Breath Condensate: Technical and Diagnostic Aspects. ScientificWorldJournal (2015) 0.77
Airway oxidative stress in chronic cough. Cough (2013) 0.77
A Review of Analytical Techniques and Their Application in Disease Diagnosis in Breathomics and Salivaomics Research. Int J Mol Sci (2016) 0.75
Parameters of lung inflammation in asthmatic as compared to healthy children in a contaminated city. BMC Pulm Med (2014) 0.75
Lessons learned from metabolomics in cystic fibrosis. Mol Cell Pediatr (2015) 0.75
Urine metabolomic profiling of children with respiratory tract infections in the emergency department: a pilot study. BMC Infect Dis (2016) 0.75
Breath tests in respiratory and critical care medicine: from research to practice in current perspectives. Biomed Res Int (2013) 0.75
Noninvasive metabolic profiling for painless diagnosis of human diseases and disorders. Future Sci OA (2016) 0.75
Metabolic Signatures of Lung Cancer in Sputum and Exhaled Breath Condensate Detected by (1)H Magnetic Resonance Spectroscopy: A Feasibility Study. Magn Reson Insights (2016) 0.75
CFTR Modulator Therapies in Pediatric Cystic Fibrosis: Focus on Ivacaftor. Expert Opin Orphan Drugs (2016) 0.75
Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics. J Am Soc Mass Spectrom (2017) 0.75
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2007) 47.86
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2012) 22.96
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Chronic obstructive pulmonary disease in non-smokers. Lancet (2009) 6.41
Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med (2005) 6.13
Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease. Lancet (2003) 3.78
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients. Chest (2002) 3.05
Relationship between serum vitamin D, disease severity, and airway remodeling in children with asthma. Am J Respir Crit Care Med (2011) 3.00
The Th17 pathway in cystic fibrosis lung disease. Am J Respir Crit Care Med (2011) 2.87
Isoprostanes: markers and mediators of oxidative stress. FASEB J (2004) 2.83
Platelet activation in obese women: role of inflammation and oxidant stress. JAMA (2002) 2.79
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med (2005) 2.72
Retracted The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma. Am J Respir Crit Care Med (2006) 2.72
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med (2009) 2.56
COPD as a disease of accelerated lung aging. Chest (2009) 2.56
Regional lung deposition and bronchodilator response as a function of beta2-agonist particle size. Am J Respir Crit Care Med (2005) 2.43
Expression and activity of histone deacetylases in human asthmatic airways. Am J Respir Crit Care Med (2002) 2.40
Longitudinal evaluation of airway function 21 years after preterm birth. Am J Respir Crit Care Med (2008) 2.35
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat Cell Biol (2010) 2.29
Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction. Am J Respir Crit Care Med (2005) 2.26
Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet (2003) 2.21
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages. J Exp Med (2004) 2.19
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A (2002) 2.17
Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet (2003) 2.16
Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". J Am Coll Cardiol (2009) 2.11
Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers. Am J Respir Crit Care Med (2007) 2.09
Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities. Am J Hum Genet (2009) 2.07
Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 2.06
Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 2.06
Molecular mechanisms of corticosteroid resistance. Chest (2008) 2.06
Quality, size, and composition of pediatric endobronchial biopsies in cystic fibrosis. Chest (2007) 2.05
Rapid diagnosis of primary ciliary dyskinesia: cell culture and soft computing analysis. Eur Respir J (2012) 2.04
Neutrophil chemotactic activity of sputum from patients with COPD: role of interleukin 8 and leukotriene B4. Chest (2003) 2.04
The European Respiratory Society plans its future: the 2013-2018 strategic plan. Eur Respir J (2014) 2.02
Oxidative stress-induced antibodies to carbonyl-modified protein correlate with severity of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 2.02
Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening. Thorax (2012) 2.01
Release and activity of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol (2002) 2.00
Early thickening of the reticular basement membrane in children with difficult asthma. Am J Respir Crit Care Med (2003) 1.94
Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy. Am J Respir Crit Care Med (2005) 1.93
Practice imperfect--treatment for wheezing in preschoolers. N Engl J Med (2009) 1.90
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease. Thorax (2012) 1.88
Prevalence of asthma among Qatari schoolchildren: International Study of Asthma and Allergies in Childhood, Qatar. Pediatr Pulmonol (2006) 1.88
Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins. Free Radic Biol Med (2007) 1.88
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol (2002) 1.84
Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 1.84
Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect (2008) 1.83
Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2002) 1.82
Cystic fibrosis. BMJ (2007) 1.82
Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis. Am J Respir Crit Care Med (2008) 1.79
Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms. Am J Physiol Lung Cell Mol Physiol (2004) 1.77
Glucocorticoids: effects on gene transcription. Proc Am Thorac Soc (2004) 1.73
Use of sputum eosinophil counts to guide management in children with severe asthma. Thorax (2011) 1.73
Lung clearance index in primary ciliary dyskinesia and bronchiectasis. Am J Respir Crit Care Med (2014) 1.73
Is exposure to biomass smoke the biggest risk factor for COPD globally? Chest (2010) 1.71
p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol Pharmacol (2011) 1.70
Airway remodelling and its relationship to inflammation in cystic fibrosis. Thorax (2010) 1.67
Increasing doses of inhaled corticosteroids compared to adding long-acting inhaled beta2-agonists in achieving asthma control. Chest (2008) 1.67
Voriconazole therapy in children with cystic fibrosis. J Cyst Fibros (2005) 1.67
Soluble RAGE in type 2 diabetes: association with oxidative stress. Free Radic Biol Med (2007) 1.67
Nitric oxide synthase isoenzyme expression and activity in peripheral lung tissue of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 1.67
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers. Am J Respir Crit Care Med (2002) 1.65
Sputum inflammatory phenotypes are not stable in children with asthma. Thorax (2012) 1.65
An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2015) 1.63
Repeatability of sodium and chloride in exhaled breath condensates. Pediatr Pulmonol (2004) 1.63
Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice. Am J Respir Crit Care Med (2009) 1.59
Chronic idiopathic cough: a discrete clinical entity? Chest (2005) 1.59
Maternally imprinted microRNAs are differentially expressed during mouse and human lung development. Dev Dyn (2007) 1.57
Clinical use of noninvasive measurements of airway inflammation in steroid reduction in children. Am J Respir Crit Care Med (2005) 1.56
Treatment of airway mucus hypersecretion. Ann Med (2006) 1.55
Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma. Am J Respir Crit Care Med (2002) 1.54
Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases. Am J Physiol Lung Cell Mol Physiol (2002) 1.53
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma. Am J Respir Crit Care Med (2004) 1.53
Rescue treatment in asthma. More than as-needed bronchodilation. Chest (2009) 1.52
Genotyping in primary ciliary dyskinesia: ready for prime time, or a fringe benefit? Thorax (2012) 1.52
Comparison of the effects of salmeterol and formoterol in patients with severe asthma. Chest (2002) 1.50
Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis. Am J Respir Crit Care Med (2004) 1.49
Symptom-pattern phenotype and pulmonary function in preschool wheezers. J Allergy Clin Immunol (2010) 1.48
A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9. FASEB J (2009) 1.47
NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. J Immunol (2006) 1.46
An update on paediatric asthma. Eur Respir Rev (2012) 1.46
Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. J Allergy Clin Immunol (2012) 1.45
Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax (2010) 1.45
Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis. Am J Respir Crit Care Med (2013) 1.45
Does lidocaine gel alleviate the pain of bladder catheterization in young children? A randomized, controlled trial. Pediatrics (2005) 1.45
Biomarkers of some pulmonary diseases in exhaled breath. Biomarkers (2002) 1.45
Dornase alfa as postoperative therapy in cystic fibrosis sinonasal disease. Arch Otolaryngol Head Neck Surg (2005) 1.44
Corticosteroids in respiratory diseases in children. Am J Respir Crit Care Med (2012) 1.44
Cystic fibrosis: keeping it in the family. Pediatr Pulmonol (2002) 1.41
A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke. JAMA (2004) 1.40
Acute, short-term hyperglycemia enhances shear stress-induced platelet activation in patients with type II diabetes mellitus. J Am Coll Cardiol (2003) 1.39
Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets. Proc Natl Acad Sci U S A (2002) 1.39
Basic science research vs. clinical research in cystic fibrosis: Has the pendulum swung too far? Pediatr Pulmonol (2003) 1.39
Microbiology of airway disease in a cohort of patients with cystic fibrosis. BMC Infect Dis (2006) 1.39
Defective glucocorticoid receptor nuclear translocation and altered histone acetylation patterns in glucocorticoid-resistant patients. J Allergy Clin Immunol (2004) 1.38
Journal policy on research funded by the tobacco industry. Thorax (2013) 1.38
Management of primary ciliary dyskinesia in European children: recommendations and clinical practice. Eur Respir J (2012) 1.38
Airway remodelling in children with cystic fibrosis. Thorax (2007) 1.38