Published in Am J Physiol Cell Physiol on July 24, 2002
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers. Neoplasia (2006) 1.14
Role of NFAT5 in inflammatory disorders associated with osmotic stress. Curr Genomics (2010) 1.10
Osmotic regulation of renal betaine transport: transcription and beyond. Pflugers Arch (2004) 1.01
Response of human cells to desiccation: comparison with hyperosmotic stress response. J Physiol (2004) 0.98
Urea promotes TonEBP expression and cellular adaptation in extreme hypertonicity. Pflugers Arch (2009) 0.85
Differential expression of heat shock protein 27 and 70 in renal papillary collecting duct and interstitial cells - implications for urea resistance. J Physiol (2005) 0.84
Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro. Arthritis Res Ther (2010) 0.82
Autocrine MCP-1/CCR2 signaling stimulates proliferation and migration of renal carcinoma cells. Oncol Lett (2016) 0.80
Drying and salting send different messages. J Physiol (2004) 0.77
Effect of ammonium on the expression of osmosensitive genes in Madin-Darby canine kidney cells. J Physiol (2004) 0.75
Antidiuretic effect of hydrochlorothiazide in lithium-induced nephrogenic diabetes insipidus is associated with upregulation of aquaporin-2, Na-Cl co-transporter, and epithelial sodium channel. J Am Soc Nephrol (2004) 1.86
Effect of renal denervation on prenatal programming of hypertension and renal tubular transporter abundance. Am J Physiol Renal Physiol (2008) 1.82
TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity. Mol Cell Biol (2002) 1.72
Maturation of TonEBP expression in developing rat kidney. Am J Physiol Renal Physiol (2004) 1.70
NF-AT5 is a critical regulator of inflammatory arthritis. Arthritis Rheum (2011) 1.68
Lean mass index: a better predictor of mortality than body mass index in elderly Asians. J Am Geriatr Soc (2010) 1.67
Chronic COX-2 inhibition reduces medullary HSP70 expression and induces papillary apoptosis in dehydrated rats. Kidney Int (2004) 1.51
Impact of C-reactive protein and pulse pressure evaluated at the start of peritoneal dialysis on cardiovascular events in the course of treatment with peritoneal dialysis. Perit Dial Int (2010) 1.43
TonEBP transcriptional activator in the cellular response to increased osmolality. Pflugers Arch (2002) 1.43
Osmoprotective transcription factor NFAT5/TonEBP modulates nuclear factor-kappaB activity. Mol Biol Cell (2010) 1.38
Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney. Nephrol Dial Transplant (2009) 1.37
Cell survival in the hostile environment of the renal medulla. Annu Rev Physiol (2005) 1.35
Clinical implications of pathologic diagnosis and classification for diabetic nephropathy. Diabetes Res Clin Pract (2012) 1.32
Prevention of acute kidney injury by erythropoietin in patients undergoing coronary artery bypass grafting: a pilot study. Am J Nephrol (2009) 1.29
Tonicity-responsive enhancer binding protein is an essential regulator of aquaporin-2 expression in renal collecting duct principal cells. J Am Soc Nephrol (2006) 1.28
Single nucleotide polymorphisms in the phospholipase A2 receptor gene are associated with genetic susceptibility to idiopathic membranous nephropathy. Nephron Clin Pract (2010) 1.23
High serum bilirubin is associated with the reduced risk of diabetes mellitus and diabetic nephropathy. Tohoku J Exp Med (2010) 1.19
Moderately decreased renal function negatively affects the health-related quality of life among the elderly Korean population: a population-based study. Nephrol Dial Transplant (2008) 1.15
Tonicity-independent regulation of the osmosensitive transcription factor TonEBP (NFAT5). Am J Physiol Cell Physiol (2011) 1.15
Silencing of TonEBP/NFAT5 transcriptional activator by RNA interference. J Am Soc Nephrol (2003) 1.12
Glibenclamide-10-h Treatment Window in a Clinically Relevant Model of Stroke. Transl Stroke Res (2012) 1.10
Comparison of experimental lung injury from acute renal failure with injury due to sepsis. Respiration (2006) 1.05
Trends in the prevalence of chronic kidney disease, other chronic diseases and health-related behaviors in an adult Korean population: data from the Korean National Health and Nutrition Examination Survey (KNHANES). Nephrol Dial Transplant (2011) 1.05
Oxytocin induces apical and basolateral redistribution of aquaporin-2 in rat kidney. Nephron Exp Nephrol (2003) 1.02
NF-kappaB modulates aquaporin-2 transcription in renal collecting duct principal cells. J Biol Chem (2008) 1.01
Multiple domains of TonEBP cooperate to stimulate transcription in response to hypertonicity. J Biol Chem (2003) 1.00
Dimerization is required for phosphorylation and DNA binding of TonEBP/NFAT5. Biochem Biophys Res Commun (2002) 1.00
Sequential expression of NKCC2, TonEBP, aldose reductase, and urea transporter-A in developing mouse kidney. Am J Physiol Renal Physiol (2006) 0.99
Hypertonic stress in the kidney: a necessary evil. Physiology (Bethesda) (2009) 0.99
The mildly elevated serum bilirubin level is negatively associated with the incidence of end stage renal disease in patients with IgA nephropathy. J Korean Med Sci (2009) 0.97
Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation. Arterioscler Thromb Vasc Biol (2011) 0.97
Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage. Stroke (2013) 0.97
The occurrence of warfarin-related nephropathy and effects on renal and patient outcomes in korean patients. PLoS One (2013) 0.97
Downregulation of renal sodium transporters and tonicity-responsive enhancer binding protein by long-term treatment with cyclosporin A. J Am Soc Nephrol (2007) 0.96
PGE2 potentiates tonicity-induced COX-2 expression in renal medullary cells in a positive feedback loop involving EP2-cAMP-PKA signaling. Am J Physiol Cell Physiol (2008) 0.96
Proteinuria and hematuria are associated with acute kidney injury and mortality in critically ill patients: a retrospective observational study. BMC Nephrol (2014) 0.96
Downregulation of renal TonEBP in hypokalemic rats. Am J Physiol Renal Physiol (2007) 0.95
Glycated haemoglobin and the incidence of end-stage renal disease in diabetics. Nephrol Dial Transplant (2010) 0.95
Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity. Am J Physiol Cell Physiol (2002) 0.95
TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways. Am J Physiol Renal Physiol (2011) 0.94
Dipeptidyl peptidase IV inhibitor attenuates kidney injury in rat remnant kidney. BMC Nephrol (2013) 0.94
RGS2 promotes formation of neurites by stimulating microtubule polymerization. Cell Signal (2006) 0.92
NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration. Front Physiol (2012) 0.92
The bilirubin level is negatively correlated with the incidence of hypertension in normotensive Korean population. J Korean Med Sci (2009) 0.92
Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis. BMC Nephrol (2013) 0.91
Survival in hostile environments: strategies of renal medullary cells. Physiology (Bethesda) (2006) 0.91
Erythropoietin improves long-term outcomes in patients with acute kidney injury after coronary artery bypass grafting. J Korean Med Sci (2012) 0.91
Adaptation of kidney medulla to hypertonicity: role of the transcription factor TonEBP. Int Rev Cytol (2002) 0.91
Prostaglandin E2 stimulates expression of osmoprotective genes in MDCK cells and promotes survival under hypertonic conditions. J Physiol (2007) 0.91
Quality of life and mortality from a nephrologist's view: a prospective observational study. BMC Nephrol (2009) 0.90
Transcriptional activator TonE-binding protein in cellular protection and differentiation. Methods Enzymol (2007) 0.90
The heme oxygenase-1 genotype is a risk factor to renal impairment of IgA nephropathy at diagnosis, which is a strong predictor of mortality. J Korean Med Sci (2009) 0.89
Hyperbilirubinemia reduces the streptozotocin-induced pancreatic damage through attenuating the oxidative stress in the Gunn rat. Tohoku J Exp Med (2010) 0.89
The urine-blood PCO gradient as a diagnostic index of H(+)-ATPase defect distal renal tubular acidosis. Kidney Int (2004) 0.89
Novel nuclear localization signal regulated by ambient tonicity in vertebrates. J Biol Chem (2008) 0.89
Interstitial tonicity controls TonEBP expression in the renal medulla. Kidney Int (2008) 0.88
Effects of potassium on expression of renal sodium transporters in salt-sensitive hypertensive rats induced by uninephrectomy. Am J Physiol Renal Physiol (2011) 0.88
NFAT5 contributes to osmolality-induced MCP-1 expression in mesothelial cells. Mediators Inflamm (2012) 0.87
Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B. Nat Cell Biol (2006) 0.87
Interleukin-10 promoter polymorphism is associated with the predisposition to the development of IgA nephropathy and focal segmental glomerulosclerosis in Korea. J Korean Med Sci (2005) 0.87
Additional role of urine output criterion in defining acute kidney injury. Nephrol Dial Transplant (2011) 0.87
Relationship between intracellular ionic strength and expression of tonicity-responsive genes in rat papillary collecting duct cells. J Physiol (2002) 0.86
Mre11-Rad50-Nbs1 complex is activated by hypertonicity. Am J Physiol Renal Physiol (2006) 0.86
EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions. Am J Physiol Renal Physiol (2009) 0.86
TonEBP is inhibited by RNA helicase A via interaction involving the E'F loop. Biochem J (2006) 0.86
Chronic ouabain treatment induces vasa recta endothelial dysfunction in the rat. Am J Physiol Renal Physiol (2008) 0.85
Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells. Kidney Int (2011) 0.85
Urea promotes TonEBP expression and cellular adaptation in extreme hypertonicity. Pflugers Arch (2009) 0.85
Higher hemoglobin level is associated with subtle declines in renal function and presence of cardiorenal risk factors in early CKD stages. Nephrol Dial Transplant (2011) 0.85
Effects of thiazide on the expression of TRPV5, calbindin-D28K, and sodium transporters in hypercalciuric rats. J Korean Med Sci (2009) 0.84
Mild decrease in estimated glomerular filtration rate and proteinuria are associated with all-cause and cardiovascular mortality in the general population. Nephrol Dial Transplant (2011) 0.84
Urea and NaCl regulate UT-A1 urea transporter in opposing directions via TonEBP pathway during osmotic diuresis. Am J Physiol Renal Physiol (2008) 0.84
Differential expression of heat shock protein 27 and 70 in renal papillary collecting duct and interstitial cells - implications for urea resistance. J Physiol (2005) 0.84
The effect of the World Kidney Day campaign on the awareness of chronic kidney disease and the status of risk factors for cardiovascular disease and renal progression. Nephrol Dial Transplant (2009) 0.84
Reduced urinary excretion of thiazide-sensitive Na-Cl cotransporter in Gitelman syndrome: preliminary data. Am J Kidney Dis (2007) 0.84
Duration of acute kidney injury and mortality in critically ill patients: a retrospective observational study. BMC Nephrol (2013) 0.84
Renal ischemia-reperfusion injury causes intercalated cell-specific disruption of occludin in the collecting duct. Histochem Cell Biol (2011) 0.83
The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis. Eur J Immunol (2014) 0.83
The low number of red blood cells is an important risk factor for all-cause mortality in the general population. Tohoku J Exp Med (2012) 0.83
Serum phosphorus as a predictor of low-grade albuminuria in a general population without evidence of chronic kidney disease. Nephrol Dial Transplant (2012) 0.83
Biocompatible peritoneal dialysis solution preserves residual renal function. Am J Nephrol (2012) 0.83
Omacor, n-3 polyunsaturated fatty acid, attenuated albuminuria and renal dysfunction with decrease of SREBP-1 expression and triglyceride amount in the kidney of type II diabetic animals. Nephrol Dial Transplant (2009) 0.83
Differential white blood cell count and all-cause mortality in the Korean elderly. Exp Gerontol (2012) 0.83
Inhibition of phospholipase C-beta1-mediated signaling by O-GlcNAc modification. J Cell Physiol (2006) 0.82
Cinacalcet lowering of serum fibroblast growth factor-23 concentration may be independent from serum Ca, P, PTH and dose of active vitamin D in peritoneal dialysis patients: a randomized controlled study. BMC Nephrol (2013) 0.82
Small increases in plasma sodium are associated with higher risk of mortality in a healthy population. J Korean Med Sci (2013) 0.82
Activation of hypoxia-inducible factor by cobalt is associated with the attenuation of tissue injury and apoptosis in cyclosporine-induced nephropathy. Tohoku J Exp Med (2012) 0.82
Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury. PLoS One (2012) 0.81
Association of angiotensin II type 2 receptor gene A1818T polymorphism with progression of immunoglobulin A nephropathy in Korean patients. J Korean Med Sci (2009) 0.81
Rapid correction rate of hyponatremia as an independent risk factor for neurological complication following liver transplantation. Tohoku J Exp Med (2013) 0.81
Osmoadaptation of Mammalian cells - an orchestrated network of protective genes. Curr Genomics (2007) 0.81