Published in Blood on August 01, 2002
Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc Natl Acad Sci U S A (2006) 3.73
Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest (2003) 2.37
Superior ex vivo cord blood expansion following co-culture with bone marrow-derived mesenchymal stem cells. Bone Marrow Transplant (2006) 2.29
Epidermal growth factor regulates hematopoietic regeneration after radiation injury. Nat Med (2013) 1.95
Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. Nat Med (2010) 1.94
Angiocrine functions of organ-specific endothelial cells. Nature (2016) 1.47
Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells. PLoS Med (2006) 1.35
Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells. Blood (2012) 1.29
Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. Blood (2006) 1.23
Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. Cell Rep (2012) 1.08
ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells. Haematologica (2015) 1.00
Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. Stem Cells (2010) 0.98
Tie2(+) bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury. Stem Cells (2013) 0.98
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. J Clin Invest (2015) 0.97
Niche heterogeneity in the bone marrow. Ann N Y Acad Sci (2016) 0.96
Endothelial cells mediate the regeneration of hematopoietic stem cells. Stem Cell Res (2009) 0.87
Mesenchymal stem cells in ex vivo cord blood expansion. Best Pract Res Clin Haematol (2011) 0.85
Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. Mol Endocrinol (2008) 0.84
Establishment and regulation of the HSC niche: Roles of osteoblastic and vascular compartments. Birth Defects Res C Embryo Today (2010) 0.84
Circulating mouse Flk1+/c-Kit+/CD45- cells function as endothelial progenitors cells (EPCs) and stimulate the growth of human tumor xenografts. Mol Cancer (2014) 0.80
Differential effects of HOXB4 and NUP98-HOXA10hd on hematopoietic repopulating cells in a nonhuman primate model. Hum Gene Ther (2011) 0.80
Engineering the hematopoietic stem cell niche: Frontiers in biomaterial science. Biotechnol J (2015) 0.80
Understanding the Pathophysiology and Challenges of Development of Medical Countermeasures for Radiation-Induced Vascular/Endothelial Cell Injuries: Report of a NIAID Workshop, August 20, 2015. Radiat Res (2016) 0.77
Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem Cells Transl Med (2016) 0.77
Optimizing autologous cell grafts to improve stem cell gene therapy. Exp Hematol (2016) 0.76
Ability of circulating human hematopoietic lineage negative cells to support hematopoiesis. J Cell Biochem (2015) 0.75
JAK2(V617F)-mutant vascular niche contributes to JAK2(V617F) clonal expansion in myeloproliferative neoplasms. Blood Cells Mol Dis (2016) 0.75
Regulation of the hematopoietic stem cell lifecycle by the endothelial niche. Curr Opin Hematol (2017) 0.75
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med (2005) 15.42
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci U S A (2003) 10.71
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med (2002) 8.84
Diabetes and cancer: a consensus report. Diabetes Care (2010) 6.71
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem (2005) 4.40
Diabetes and cancer: a consensus report. CA Cancer J Clin (2010) 3.95
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology (2003) 3.93
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res (2005) 3.35
Survival after pancreas transplantation in patients with diabetes and preserved kidney function. JAMA (2003) 3.33
Ontology-based meta-analysis of global collections of high-throughput public data. PLoS One (2010) 2.67
Insulin secretion in type 1 diabetes. Diabetes (2004) 2.59
Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients. Blood (2002) 2.52
Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H). Transplantation (2003) 2.48
Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol (2005) 2.36
A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy. Clin Cancer Res (2007) 2.24
Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke (2006) 2.02
Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes. Diabetes Care (2009) 2.02
Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway. Endocrinology (2002) 1.95
Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience. Diabetes Care (2003) 1.86
Evaluating the role of epigenetic histone modifications in the metabolic memory of type 1 diabetes. Diabetes (2014) 1.81
Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes. Diabetes Care (2013) 1.81
Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy. Lancet (2002) 1.76
Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell (2008) 1.60
Heterotopic ossification following combat-related trauma. J Bone Joint Surg Am (2010) 1.51
Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest (2004) 1.50
Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function. J Biol Chem (2009) 1.49
Ethnicity greatly influences cytokine gene polymorphism distribution. Am J Transplant (2002) 1.48
Inflammatory biomarkers in combat wound healing. Ann Surg (2009) 1.45
FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm. Cell Stem Cell (2012) 1.39
Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol (2003) 1.35
Systemic distribution of West Nile virus infection: postmortem immunohistochemical study of six cases. Brain Pathol (2007) 1.30
Genistein protects against biomarkers of delayed lung sequelae in mice surviving high-dose total body irradiation. J Radiat Res (2008) 1.29
Contralateral hemimicrencephaly and clinical-pathological correlations in children with hemimegalencephaly. Brain (2005) 1.24
Extramedullary relapses after allogeneic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome. Haematologica (2010) 1.23
Pancreatic islet transplantation. PLoS Med (2004) 1.21
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. Biochim Biophys Acta (2011) 1.17
Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging. Transplantation (2005) 1.15
Transcriptional analysis of intracytoplasmically stained, FACS-purified cells by high-throughput, quantitative nuclease protection. Nat Biotechnol (2009) 1.13
Comorbidity in dementia: an autopsy study. Arch Pathol Lab Med (2004) 1.12
Blood glucose levels regulate pancreatic beta-cell proliferation during experimentally-induced and spontaneous autoimmune diabetes in mice. PLoS One (2009) 1.11
Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance. Mol Endocrinol (2004) 1.10
Dynamic changes in pancreatic endocrine cell abundance, distribution, and function in antigen-induced and spontaneous autoimmune diabetes. Diabetes (2009) 1.10
Osteogenic gene expression correlates with development of heterotopic ossification in war wounds. Clin Orthop Relat Res (2013) 1.07
Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes. Diabetes Technol Ther (2011) 1.07
Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt. J Immunol (2010) 1.05
A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets. Endocrinology (2002) 1.05
Patterns of care in a population-based random sample of patients diagnosed with non-Hodgkin's lymphoma. Hematol Oncol (2005) 1.04
Lymphocyte modulation with FTY720 improves hemorrhagic shock survival in swine. PLoS One (2012) 1.03
The majority of US combat casualty soft-tissue wounds are not infected or colonized upon arrival or during treatment at a continental US military medical facility. Am J Surg (2010) 1.01
Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations. PLoS One (2009) 0.99
Pluripotent stem cell-based cancer therapy: promise and challenges. Sci Transl Med (2012) 0.99
T cell-directed therapies: lessons learned and future prospects. Nat Immunol (2007) 0.98
Differences in the management of type 1 diabetes among adults under excellent control compared with those under poor control in the T1D Exchange Clinic Registry. Diabetes Care (2013) 0.97
Resistin is expressed in pancreatic islets. Biochem Biophys Res Commun (2003) 0.97
Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site. Diabetes (2002) 0.96
Disruption of CD40/CD40-ligand interactions in a retinal autoimmunity model results in protection without tolerance. J Immunol (2005) 0.96
Improving MRI differentiation of gray and white matter in epileptogenic lesions based on nonlinear feedback. Magn Reson Med (2006) 0.94
Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation. J Transl Med (2007) 0.94
N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Surgery (2011) 0.94
Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation. J Immunol (2003) 0.94
Generation and genetic engineering of human induced pluripotent stem cells using designed zinc finger nucleases. Stem Cells Dev (2012) 0.93
Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. Pancreas (2010) 0.93
The contribution of Fc effector mechanisms in the efficacy of anti-CD154 immunotherapy depends on the nature of the immune challenge. Int Immunol (2004) 0.93
Topical advances in wound care. Gynecol Oncol (2008) 0.93
Insulinomas and expression of an insulin splice variant. Lancet (2004) 0.93
Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci (2011) 0.92
Angiogenic response to extracorporeal shock wave treatment in murine skin isografts. Angiogenesis (2008) 0.89
Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. Pancreas (2010) 0.89
Extrapancreatic autoantibody profiles in type I diabetes. PLoS One (2012) 0.88
Autopsy findings after intracranial thrombectomy for acute ischemic stroke: a clinicopathologic study of 5 patients. Stroke (2010) 0.87
Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response. Clin Exp Metastasis (2007) 0.87
Combination induction therapy with monoclonal antibodies specific for CD80, CD86, and CD154 in nonhuman primate renal transplantation. Transplantation (2002) 0.87
Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model. Am J Transplant (2002) 0.87
Epigenetic induction of adaptive immune response in multiple myeloma: sequential azacitidine and lenalidomide generate cancer testis antigen-specific cellular immunity. Br J Haematol (2012) 0.87
CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer. Expert Rev Vaccines (2011) 0.85
Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression. J Clin Endocrinol Metab (2002) 0.85
Induction of diabetes in nonhuman primates by means of temporary arterial embolization and selective arterial injection of streptozotocin. Radiology (2004) 0.85
Comparative analysis of gene transcripts for cell signaling receptors in bone marrow-derived hematopoietic stem/progenitor cell and mesenchymal stromal cell populations. Stem Cell Res Ther (2013) 0.85
Sirolimus-induced interstitial pneumonitis in an islet transplant recipient. Diabetes Care (2003) 0.84
Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes. Diabetes Care (2009) 0.84
Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates. Transplantation (2002) 0.84
Favorable outcomes in patients with high donor-derived T cell count after in vivo T cell-depleted reduced-intensity allogeneic stem cell transplantation. Biol Blood Marrow Transplant (2011) 0.84
Increased risk of lethal graft-versus-host disease-like syndrome after transplantation into NOD/SCID mice of human mobilized peripheral blood stem cells, as compared to bone marrow or cord blood. J Hematother Stem Cell Res (2002) 0.84
Diagnosis and management of abdominal pregnancy. A case report. J Reprod Med (2002) 0.84
Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. Kidney Int (2004) 0.84
Counterpoint: clinical islet transplantation: not ready for prime time. Diabetes Care (2009) 0.83
Beta cell-specific CD80 (B7-1) expression disrupts tissue protection from autoantigen-specific CTL-mediated diabetes. J Autoimmun (2003) 0.83
Comparative analysis of angiogenic gene expression in normal and impaired wound healing in diabetic mice: effects of extracorporeal shock wave therapy. Angiogenesis (2010) 0.83
Moderate and severe traumatic brain injury: epidemiologic, imaging and neuropathologic perspectives. Brain Pathol (2004) 0.83
Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies. Biol Blood Marrow Transplant (2011) 0.83
Immune intervention with anti-CD3 in diabetes. Nat Med (2005) 0.83
Bioburden Increases Heterotopic Ossification Formation in an Established Rat Model. Clin Orthop Relat Res (2015) 0.83
Analysis of the control of the anti-gal immune response in a non-human primate by galactose alpha1-3 galactose trisaccharide-polyethylene glycol conjugate. Transplantation (2002) 0.82
Lissencephaly with agenesis of corpus callosum and rudimentary dysplastic cerebellum: a subtype of lissencephaly with cerebellar hypoplasia. Acta Neuropathol (2003) 0.82
Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model. Transplantation (2003) 0.82
Development of a Bayesian model to estimate health care outcomes in the severely wounded. J Multidiscip Healthc (2010) 0.82
Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice. J Inflamm (Lond) (2010) 0.82
Assessment of islet function following islet and pancreas transplantation. Curr Diab Rep (2006) 0.81
Islet transplantation: where do we stand now? Diabetes Metab Res Rev (2003) 0.81