Published in Mol Med on July 01, 2002
Cytokine regulation of tight junctions. Biochim Biophys Acta (2008) 2.16
Mechanism of cytokine modulation of epithelial tight junction barrier. Front Biosci (Landmark Ed) (2009) 1.57
Retracted Dextran sulfate sodium inhibits alanine synthesis in Caco-2 cells. Int J Mol Sci (2011) 1.39
The immunobiology of primary sclerosing cholangitis. Semin Immunopathol (2009) 1.15
Alteration in intestine tight junction protein phosphorylation and apoptosis is associated with increase in IL-18 levels following alcohol intoxication and burn injury. Biochim Biophys Acta (2011) 0.99
Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene. PLoS One (2014) 0.89
PPAR-alpha Contributes to the Anti-Inflammatory Activity of Verbascoside in a Model of Inflammatory Bowel Disease in Mice. PPAR Res (2010) 0.82
Modulation of VEGF-induced retinal vascular permeability by peroxisome proliferator-activated receptor-β/δ. Invest Ophthalmol Vis Sci (2014) 0.82
Schistosoma japonicum ova maintains epithelial barrier function during experimental colitis. World J Gastroenterol (2011) 0.80
Gleaning Insights from Fecal Microbiota Transplantation and Probiotic Studies for the Rational Design of Combination Microbial Therapies. Clin Microbiol Rev (2017) 0.78
TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway. Am J Pathol (2016) 0.78
Transitory loss of glia and the subsequent modulation in inflammatory cytokines/chemokines regulate paracellular claudin-5 expression in endothelial cells. J Neuroimmunol (2015) 0.75
Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients. Circulation (2009) 3.39
Abandon the mouse research ship? Not just yet! Shock (2014) 2.60
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects. Nat Med (2003) 2.24
A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther (2004) 2.21
Association of community-acquired pneumonia with antipsychotic drug use in elderly patients: a nested case-control study. Ann Intern Med (2010) 1.91
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies. Br J Pharmacol (2003) 1.77
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J (2002) 1.73
Adverse reactions to contrast media: an analysis from spontaneous reporting data. Pharmacol Res (2007) 1.68
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. Free Radic Biol Med (2008) 1.65
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci U S A (2009) 1.64
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R. Shock (2009) 1.60
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol Rev (2005) 1.57
Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain. Pain (2011) 1.55
Prevalence estimates for chronic diseases in Italy: exploring the differences between self-report and primary care databases. J Public Health Med (2003) 1.54
GITR/GITRL: more than an effector T cell co-stimulatory system. Eur J Immunol (2007) 1.53
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol (2007) 1.53
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice. Intensive Care Med (2003) 1.52
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation. Eur J Pharmacol (2004) 1.50
Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice. Arthritis Res Ther (2013) 1.49
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat. Crit Care Med (2002) 1.49
Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome. Intensive Care Med (2006) 1.49
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice. Crit Care Med (2004) 1.48
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. Br J Pharmacol (2002) 1.47
Hyperbaric oxygen therapy prevents vascular derangement during zymosan-induced multiple-organ-failure syndrome. Intensive Care Med (2004) 1.45
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma. FASEB J (2006) 1.42
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta (2011) 1.40
Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion. J Pharmacol Exp Ther (2004) 1.39
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models. Am J Pathol (2003) 1.39
Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion. Diabetes (2005) 1.37
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. J Clin Invest (2007) 1.37
A case of topiramate-induced epistaxis. Curr Drug Saf (2009) 1.37
Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats. J Nutr (2009) 1.34
A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury. J Neuroinflammation (2013) 1.34
Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation. Brain Res Rev (2007) 1.33
SOD mimetics are coming of age. Nat Rev Drug Discov (2002) 1.32
Patterns of persistence with antihypertensive medications in newly diagnosed hypertensive patients in Italy: a retrospective cohort study in primary care. J Hypertens (2005) 1.31
Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population. Pharmacol Res (2004) 1.31
Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation. Respir Res (2007) 1.29
5-Arylidene-2-imino-4-thiazolidinones: design and synthesis of novel anti-inflammatory agents. Bioorg Med Chem (2005) 1.29
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. Mol Pharmacol (2002) 1.29
Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity. Mol Aspects Med (2011) 1.27
Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. Brain Behav Immun (2011) 1.27
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int (2004) 1.26
Immunomodulatory effects of etanercept in an experimental model of spinal cord injury. J Pharmacol Exp Ther (2005) 1.25
Epidemiology of gout and hyperuricaemia in Italy during the years 2005-2009: a nationwide population-based study. Ann Rheum Dis (2012) 1.25
Uric acid protects against secondary damage after spinal cord injury. Proc Natl Acad Sci U S A (2005) 1.24
Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain. J Neurosci (2012) 1.21
Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-alpha) in the development of inflammatory bowel disease in mice. Lab Invest (2004) 1.20
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice. J Pharmacol Exp Ther (2007) 1.18
Traumatic brain injury: oxidative stress and neuroprotection. Antioxid Redox Signal (2013) 1.18
Oxidative stress in septic shock and disseminated intravascular coagulation. Free Radic Biol Med (2002) 1.18
Oxidative stress as the leading cause of acute myocardial infarction in diabetics. Cardiovasc Drug Rev (2006) 1.17
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest (2004) 1.17
Dexamethasone ameliorates renal ischemia-reperfusion injury. J Am Soc Nephrol (2009) 1.17
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int (2003) 1.16
Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway. Cardiovasc Res (2004) 1.15
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury. Kidney Int (2002) 1.15
Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes. Diabetes (2004) 1.15
Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. Eur J Pharmacol (2009) 1.14
Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. Gastroenterology (2008) 1.14
The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation. J Leukoc Biol (2006) 1.13
Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence. Shock (2007) 1.13
Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury. J Pharmacol Exp Ther (2008) 1.12
All-cause mortality associated with atypical and typical antipsychotics in demented outpatients. Pharmacoepidemiol Drug Saf (2007) 1.11
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis. FASEB J (2005) 1.11
Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin. J Pineal Res (2005) 1.11
Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways. Free Radic Biol Med (2008) 1.10
Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice. Pharmacol Res (2008) 1.10
Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats. Neurosci Lett (2011) 1.10
The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock. Intensive Care Med (2005) 1.10
Antiinflammatory activity of melatonin in central nervous system. Curr Neuropharmacol (2010) 1.09
Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies. Am J Physiol Gastrointest Liver Physiol (2008) 1.09
Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity. FASEB J (2008) 1.08
Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation. Shock (2006) 1.08
The effect of the phytoestrogen genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal women. Atherosclerosis (2002) 1.08
Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury. Shock (2002) 1.08
The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. Brain (2009) 1.07
Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. J Pharmacol Exp Ther (2008) 1.07
Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut. Br J Pharmacol (2003) 1.07
Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice. PLoS One (2013) 1.06
Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice. Diabetes (2004) 1.06
Protective effects of a coumarin derivative in diabetic rats. Invest Ophthalmol Vis Sci (2009) 1.06
Anti-TNF therapy in the injured spinal cord. Trends Pharmacol Sci (2010) 1.05
TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome. Shock (2008) 1.05
Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. J Pharmacol Exp Ther (2007) 1.05
Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury. Am J Nephrol (2003) 1.05
Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation. J Immunol (2006) 1.04
Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma. Arthritis Rheum (2003) 1.04
Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse. Clin Immunol (2006) 1.04
Role of TNF-alpha in ileum tight junction alteration in mouse model of restraint stress. Am J Physiol Gastrointest Liver Physiol (2008) 1.03
Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines. Blood (2005) 1.03
How much are biosimilars used in southern Italy?: a retrospective analysis of epoetin utilization in the local health unit of Messina in the years 2010-2011. BioDrugs (2012) 1.03
Inhibition of the nuclear factor-kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats. J Neurosurg Spine (2004) 1.02
Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock. Shock (2005) 1.02
CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation. Eur J Pharmacol (2011) 1.01
Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis. Shock (2003) 1.01
Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir Res (2005) 1.01
Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo. J Pharmacol Exp Ther (2008) 1.01