Published in Brain on June 15, 2009
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug. Nat Commun (2015) 1.10
Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation. J Biol Chem (2011) 1.05
Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants. Br J Pharmacol (2010) 1.02
Post-ischemic inflammation regulates neural damage and protection. Front Cell Neurosci (2014) 0.97
The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells. J Biol Chem (2013) 0.97
Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach. BMC Struct Biol (2010) 0.91
Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury. Purinergic Signal (2013) 0.88
Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies. J Neuroinflammation (2014) 0.85
Glucocorticoid-induced leucine zipper (GILZ) over-expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury. Neurotherapeutics (2012) 0.84
Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration. Purinergic Signal (2011) 0.84
Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage. Prostaglandins Leukot Essent Fatty Acids (2011) 0.84
Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death. Purinergic Signal (2012) 0.83
The ependymal region of the adult human spinal cord differs from other species and shows ependymoma-like features. Brain (2015) 0.83
Olprinone attenuates the acute inflammatory response and apoptosis after spinal cord trauma in mice. PLoS One (2010) 0.83
Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor. J Cereb Blood Flow Metab (2014) 0.81
Up-regulation of Smurf1 after spinal cord injury in adult rats. J Mol Histol (2013) 0.80
Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival, proliferation and final fate. Philos Trans R Soc Lond B Biol Sci (2016) 0.79
LIN28 expression in rat spinal cord after injury. Neurochem Res (2014) 0.79
Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer. Front Cell Dev Biol (2016) 0.77
Spatiotemporal pattern of TRAF3 expression after rat spinal cord injury. J Mol Histol (2014) 0.77
Expression of dual nucleotides/cysteinyl-leukotrienes receptor GPR17 in early trafficking of cardiac stromal cells after myocardial infarction. J Cell Mol Med (2014) 0.76
Expression of G-protein-coupled receptor kinase 6 (GRK6) after acute spinal cord injury in adult rat. J Mol Histol (2013) 0.76
Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury. Front Pharmacol (2016) 0.76
A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro. Purinergic Signal (2016) 0.75
Emerging role of extracellular nucleotides and adenosine in multiple sclerosis. Purinergic Signal (2011) 0.75
Update on Inflammatory Biomarkers and Treatments in Ischemic Stroke. Int J Mol Sci (2016) 0.75
Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors. Psychopharmacology (Berl) (2017) 0.75
Role of the Cysteinyl Leukotrienes in the Pathogenesis and Progression of Cardiovascular Diseases. Mediators Inflamm (2017) 0.75
Upregulation of myelin and lymphocyte protein (MAL) after traumatic spinal cord injury in rats. J Mol Histol (2012) 0.75
Abandon the mouse research ship? Not just yet! Shock (2014) 2.60
Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation (2009) 2.58
Storage and release of ATP from astrocytes in culture. J Biol Chem (2002) 2.50
A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects. Nat Med (2003) 2.24
A newly identified role for superoxide in inflammatory pain. J Pharmacol Exp Ther (2004) 2.21
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. EMBO J (2006) 2.17
Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis. PLoS Biol (2011) 1.92
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies. Br J Pharmacol (2003) 1.77
Purinergic signalling: from normal behaviour to pathological brain function. Prog Neurobiol (2011) 1.76
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. FASEB J (2002) 1.73
Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. Free Radic Biol Med (2008) 1.65
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci U S A (2009) 1.64
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R. Shock (2009) 1.60
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol Rev (2005) 1.57
Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain. Pain (2011) 1.55
Misdiagnosed chronic pelvic pain: pudendal neuralgia responding to a novel use of palmitoylethanolamide. Pain Med (2010) 1.54
Nucleotide-mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors. Glia (2003) 1.54
GITR/GITRL: more than an effector T cell co-stimulatory system. Eur J Immunol (2007) 1.53
Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase. J Am Soc Nephrol (2007) 1.53
Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice. Intensive Care Med (2003) 1.52
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation. Eur J Pharmacol (2004) 1.50
Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice. Arthritis Res Ther (2013) 1.49
Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat. Crit Care Med (2002) 1.49
Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome. Intensive Care Med (2006) 1.49
Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice. Crit Care Med (2007) 1.48
Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice. Crit Care Med (2004) 1.48
Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation. Br J Pharmacol (2002) 1.47
Hyperbaric oxygen therapy prevents vascular derangement during zymosan-induced multiple-organ-failure syndrome. Intensive Care Med (2004) 1.45
Exploiting the Burkholderia pseudomallei acute phase antigen BPSL2765 for structure-based epitope discovery/design in structural vaccinology. Chem Biol (2013) 1.45
Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy. Cancer Res (2003) 1.45
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One (2008) 1.44
Horner syndrome following thyroidectomy. Neurol Sci (2010) 1.43
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma. FASEB J (2006) 1.42
Recurrent occipital seizures misdiagnosed as status migrainosus. Epileptic Disord (2011) 1.42
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta (2011) 1.40
To be or not to be (inflamed)--is that the question in anti-inflammatory drug therapy of neurodegenerative disorders? Trends Pharmacol Sci (2005) 1.39
Fibromuscular dysplasia as a rare cause of severe ischemic stroke in a young man. Arq Neuropsiquiatr (2011) 1.39
Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion. J Pharmacol Exp Ther (2004) 1.39
Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models. Am J Pathol (2003) 1.39
Spontaneous formation of L-isoaspartate and gain of function in fibronectin. J Biol Chem (2006) 1.39
Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav (2012) 1.39
Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion. Diabetes (2005) 1.37
Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy. Cancer Res (2006) 1.37
A case of topiramate-induced epistaxis. Curr Drug Saf (2009) 1.37
Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. J Clin Invest (2007) 1.37
Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats. J Nutr (2009) 1.34
A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury. J Neuroinflammation (2013) 1.34
Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation. Brain Res Rev (2007) 1.33
CYP4F2 genetic variant (rs2108622) significantly contributes to warfarin dosing variability in the Italian population. Pharmacogenomics (2009) 1.32
Purinergic signalling in inflammation of the central nervous system. Trends Neurosci (2009) 1.32
SOD mimetics are coming of age. Nat Rev Drug Discov (2002) 1.32
Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation. Respir Res (2007) 1.29
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation. Mol Pharmacol (2002) 1.29
5-Arylidene-2-imino-4-thiazolidinones: design and synthesis of novel anti-inflammatory agents. Bioorg Med Chem (2005) 1.29
Cancer immunotherapy based on killing of Salmonella-infected tumor cells. Cancer Res (2005) 1.28
Mechanisms underlying the neuronal calcium sensor-1-evoked enhancement of exocytosis in PC12 cells. J Biol Chem (2002) 1.28
Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity. Mol Aspects Med (2011) 1.27
Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. Brain Behav Immun (2011) 1.27
Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes. J Biol Chem (2003) 1.27
Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor. Biochem Pharmacol (2004) 1.26
PHOX2B regulates its own expression by a transcriptional auto-regulatory mechanism. J Biol Chem (2005) 1.26
Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo. Kidney Int (2004) 1.26
Key concepts and critical issues on epoetin and filgrastim biosimilars. A position paper from the Italian Society of Hematology, Italian Society of Experimental Hematology, and Italian Group for Bone Marrow Transplantation. Haematologica (2011) 1.25
Immunomodulatory effects of etanercept in an experimental model of spinal cord injury. J Pharmacol Exp Ther (2005) 1.25
Uric acid protects against secondary damage after spinal cord injury. Proc Natl Acad Sci U S A (2005) 1.24
Pathophysiological roles of extracellular nucleotides in glial cells: differential expression of purinergic receptors in resting and activated microglia. Brain Res Brain Res Rev (2005) 1.24
A role for superoxide in gentamicin-mediated nephropathy in rats. Eur J Pharmacol (2002) 1.23
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif. J Biol Chem (2002) 1.22
Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain. J Neurosci (2012) 1.21
Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-alpha) in the development of inflammatory bowel disease in mice. Lab Invest (2004) 1.20
Acute intracerebroventricular administration of palmitoylethanolamide, an endogenous peroxisome proliferator-activated receptor-alpha agonist, modulates carrageenan-induced paw edema in mice. J Pharmacol Exp Ther (2007) 1.18
Traumatic brain injury: oxidative stress and neuroprotection. Antioxid Redox Signal (2013) 1.18
Carcinoembryonic antigen-specific but not antiviral CD4+ T cell immunity is impaired in pancreatic carcinoma patients. J Immunol (2008) 1.18
Cholesterol reduction impairs exocytosis of synaptic vesicles. J Cell Sci (2010) 1.18
Oxidative stress in septic shock and disseminated intravascular coagulation. Free Radic Biol Med (2002) 1.18
Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest (2004) 1.17
Oxidative stress as the leading cause of acute myocardial infarction in diabetics. Cardiovasc Drug Rev (2006) 1.17
Dexamethasone ameliorates renal ischemia-reperfusion injury. J Am Soc Nephrol (2009) 1.17
CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors. Biochem Pharmacol (2005) 1.17
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. Kidney Int (2003) 1.16
A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock. J Pharmacol Exp Ther (2006) 1.15
Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury. Kidney Int (2002) 1.15