Published in J Biol Chem on October 25, 2002
Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions. Endocrinology (2009) 1.78
Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Res (2010) 1.76
Pituitary hypoplasia in Pttg-/- mice is protective for Rb+/- pituitary tumorigenesis. Mol Endocrinol (2005) 1.40
The transcription factor p53: not a repressor, solely an activator. Cell Cycle (2014) 1.23
One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor. J Biomed Biotechnol (2011) 1.14
Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63. Nucleic Acids Res (2006) 1.13
PTTG/securin activates expression of p53 and modulates its function. Mol Cancer (2004) 1.11
Inhibition of CBF/NF-Y mediated transcription activation arrests cells at G2/M phase and suppresses expression of genes activated at G2/M phase of the cell cycle. Nucleic Acids Res (2006) 1.05
PTTG: an important target gene for ovarian cancer therapy. J Ovarian Res (2008) 1.01
Human full-length Securin is a natively unfolded protein. Protein Sci (2005) 0.96
The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop. Oncotarget (2015) 0.95
The emerging role of pituitary tumor transforming gene in tumorigenesis. Clin Med Res (2006) 0.92
Securin is a target of the UV response pathway in mammalian cells. Mol Cell Biol (2004) 0.89
Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice. PLoS One (2011) 0.85
E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors. Mol Endocrinol (2009) 0.84
Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene. FEBS Lett (2010) 0.83
Isolation and characterization of novel pituitary tumor related genes: a cDNA representational difference approach. Mol Cell Endocrinol (2010) 0.81
Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors. Endocr Relat Cancer (2008) 0.80
Methylation alterations are not a major cause of PTTG1 misregulation. BMC Cancer (2008) 0.77
Securin enhances the anti-cancer effects of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075) in human colorectal cancer cells. PLoS One (2012) 0.77
Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation. PLoS One (2013) 0.76
Efficacy and safety of benazepril for advanced chronic renal insufficiency. N Engl J Med (2006) 6.25
Activation of p53 by MEG3 non-coding RNA. J Biol Chem (2007) 3.07
Previously suicidal adolescents: predictors of six-month outcome. J Can Acad Child Adolesc Psychiatry (2008) 2.98
Mortality risk among children initially treated with dialysis for end-stage kidney disease, 1990-2010. JAMA (2013) 2.74
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab (2003) 2.68
MEG3 noncoding RNA: a tumor suppressor. J Mol Endocrinol (2012) 2.41
Effects of prolonged and exclusive breastfeeding on child behavior and maternal adjustment: evidence from a large, randomized trial. Pediatrics (2008) 2.30
To clean or not to clean: effect on contamination rates in midstream urine collections in toilet-trained children. Pediatrics (2007) 2.20
Colposcopically directed biopsy, random cervical biopsy, and endocervical curettage in the diagnosis of cervical intraepithelial neoplasia II or worse. Am J Obstet Gynecol (2004) 2.16
High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization. Carcinogenesis (2004) 2.13
Renoprotection of Optimal Antiproteinuric Doses (ROAD) Study: a randomized controlled study of benazepril and losartan in chronic renal insufficiency. J Am Soc Nephrol (2007) 2.09
Analyzing risks of adverse pregnancy outcomes. Am J Epidemiol (2013) 2.00
Bleeding complications associated with combinations of aspirin, thienopyridine derivatives, and warfarin in elderly patients following acute myocardial infarction. Arch Intern Med (2005) 1.91
Pooled analysis of a self-sampling HPV DNA Test as a cervical cancer primary screening method. J Natl Cancer Inst (2012) 1.86
Association between age and graft failure rates in young kidney transplant recipients. Transplantation (2011) 1.85
Checking stationarity of the incidence rate using prevalent cohort survival data. Stat Med (2006) 1.84
A pilot study of low-cost, high-resolution microendoscopy as a tool for identifying women with cervical precancer. Cancer Prev Res (Phila) (2012) 1.84
A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsa-miR-31 for prognosis. Clin Cancer Res (2011) 1.82
Spectrum of neurodevelopmental disabilities in children with cerebellar malformations. Dev Med Child Neurol (2011) 1.70
Cerebellar malformations alter regional cerebral development. Dev Med Child Neurol (2011) 1.42
High Risk of Liver Allograft Failure During Late Adolescence and Young Adulthood. Transplantation (2016) 1.42
The case against customised birthweight standards. Paediatr Perinat Epidemiol (2010) 1.36
Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J Clin Endocrinol Metab (2005) 1.34
The Pediatric Respiratory Assessment Measure: a valid clinical score for assessing acute asthma severity from toddlers to teenagers. J Pediatr (2007) 1.33
Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas. J Clin Endocrinol Metab (2008) 1.33
Prevalence of human papillomavirus and cervical intraepithelial neoplasia in China: a pooled analysis of 17 population-based studies. Int J Cancer (2012) 1.32
The role of interleukin-1 in wound biology. Part II: In vivo and human translational studies. Anesth Analg (2010) 1.32
1,25-Dihydroxyvitamin D improved the free fatty-acid-induced insulin resistance in cultured C2C12 cells. Diabetes Metab Res Rev (2008) 1.32
Amplification and overexpression of CTTN (EMS1) contribute to the metastasis of esophageal squamous cell carcinoma by promoting cell migration and anoikis resistance. Cancer Res (2006) 1.29
Clinicopathological features and prognosis assessment of extranodal follicular dendritic cell sarcoma. World J Gastroenterol (2010) 1.29
Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development (2010) 1.28
Advanced oxidation protein products activate vascular endothelial cells via a RAGE-mediated signaling pathway. Antioxid Redox Signal (2008) 1.27
Elevated expression of p63 protein in human esophageal squamous cell carcinomas. Int J Cancer (2002) 1.26
Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control. Am J Respir Crit Care Med (2010) 1.24
Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. Int J Cancer (2006) 1.23
Development of a new permeability assay using low-efflux MDCKII cells. J Pharm Sci (2011) 1.21
Increased expression of angiogenic genes in the brains of mouse meg3-null embryos. Endocrinology (2010) 1.19
Advanced oxidation protein products accelerate atherosclerosis through promoting oxidative stress and inflammation. Arterioscler Thromb Vasc Biol (2006) 1.19
In silico and in vitro pharmacogenetic analysis in mice. Proc Natl Acad Sci U S A (2007) 1.17
The role of interleukin-1 in wound biology. Part I: Murine in silico and in vitro experimental analysis. Anesth Analg (2010) 1.16
Advanced oxidation protein products accelerate renal fibrosis in a remnant kidney model. J Am Soc Nephrol (2007) 1.15
Determinants and consequences of discrepancies in menstrual and ultrasonographic gestational age estimates. BJOG (2005) 1.14
Human papillomavirus type-distribution in cervical cancer in China: the importance of HPV 16 and 18. Cancer Causes Control (2009) 1.14
Impacts of preference and geography on epidemic spreading. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.13
The effects of SOM230 on cell proliferation and adrenocorticotropin secretion in human corticotroph pituitary adenomas. J Clin Endocrinol Metab (2006) 1.12
DNA methylation-mediated repression of miR-886-3p predicts poor outcome of human small cell lung cancer. Cancer Res (2013) 1.11
An evaluation of novel, lower-cost molecular screening tests for human papillomavirus in rural China. Cancer Prev Res (Phila) (2013) 1.10
Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol (2012) 1.10
An anesthetic management protocol to decrease respiratory complications after adenotonsillectomy in children with severe sleep apnea. Anesth Analg (2010) 1.09
Advanced oxidation protein products promote inflammation in diabetic kidney through activation of renal nicotinamide adenine dinucleotide phosphate oxidase. Endocrinology (2008) 1.08
Enhanced expression of receptor for advanced glycation end products in chronic kidney disease. J Am Soc Nephrol (2004) 1.08
High rates of unsuccessful transfer to adult care among young adults with juvenile idiopathic arthritis. Pediatr Rheumatol Online J (2010) 1.08
Regardless of skill, performing more biopsies increases the sensitivity of colposcopy. J Low Genit Tract Dis (2011) 1.07
Ethanol extraction of Picrorhiza scrophulariiflora prevents renal injury in experimental diabetes via anti-inflammation action. J Endocrinol (2008) 1.05
Receptor for advanced glycation end products on human synovial fibroblasts: role in the pathogenesis of dialysis-related amyloidosis. J Am Soc Nephrol (2002) 1.03
Lower cost strategies for triage of human papillomavirus DNA-positive women. Int J Cancer (2013) 1.02
Regional cerebellar volumes predict functional outcome in children with cerebellar malformations. Cerebellum (2012) 1.01
Silencing of the imprinted DLK1-MEG3 locus in human clinically nonfunctioning pituitary adenomas. Am J Pathol (2011) 1.01
Molecular epidemiology and functional assessment of novel allelic variants of SLC26A4 in non-syndromic hearing loss patients with enlarged vestibular aqueduct in China. PLoS One (2012) 1.01
APC modeling of smoking prevalence among US adolescents and young adults. Am J Health Behav (2011) 1.00
Polymethylated DOTA ligands. 2. Synthesis of rigidified lanthanide chelates and studies on the effect of alkyl substitution on conformational mobility and relaxivity. Inorg Chem (2002) 1.00
An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity. Genome Res (2009) 0.98
A thin-layer, liquid-based pap test for mass screening in an area of China with a high incidence of cervical carcinoma. A cross-sectional, comparative study. Acta Cytol (2003) 0.98
Prevalence of HPV Infection And Cervical Intraepithelial Neoplasia And Attitudes towards HPV Vaccination among Chinese Women Aged 18-25 in Jiangsu Province. Chin J Cancer Res (2011) 0.97
Cyclic AMP stimulates MEG3 gene expression in cells through a cAMP-response element (CRE) in the MEG3 proximal promoter region. Int J Biochem Cell Biol (2006) 0.96
Acute and acute-on-chronic kidney injury of patients with decompensated heart failure: impact on outcomes. BMC Nephrol (2012) 0.94
Neoadjuvant chemoradiotherapy could improve survival outcomes for esophageal carcinoma: a meta-analysis. Dig Dis Sci (2012) 0.94
CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma. Cancer Lett (2002) 0.93
Common molecular etiologies are rare in nonsyndromic Tibetan Chinese patients with hearing impairment. PLoS One (2012) 0.93
Aurora-A as an independent molecular prognostic marker in gastric cancer. Oncol Rep (2011) 0.93
Cost savings associated with post-thyroidectomy parathyroid hormone levels. Otolaryngol Head Neck Surg (2008) 0.92
Baseline prevalence and type distribution of human papillomavirus in healthy Chinese women aged 18-25 years enrolled in a clinical trial. Int J Cancer (2014) 0.92
Expression of epidermal growth factor receptor is an independent prognostic factor for esophageal squamous cell carcinoma. World J Surg Oncol (2013) 0.92
Previous head injury is a risk factor for subsequent head injury in children: a longitudinal cohort study. Pediatrics (2007) 0.92
MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma. Mol Cell Biochem (2013) 0.92
Electronically programmable, reversible shape change in two- and three-dimensional hydrogel structures. Adv Mater (2012) 0.91
Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion. J Hepatol (2011) 0.91
p16INK4A immunohistochemical staining and predictive value for progression of cervical intraepithelial neoplasia grade 1: a prospective study in China. Int J Cancer (2013) 0.90
Human papillomavirus testing for cervical cancer screening: results from a 6-year prospective study in rural China. Am J Epidemiol (2009) 0.90
Efficacy, immunogenicity and safety of the HPV-16/18 AS04-adjuvanted vaccine in healthy Chinese women aged 18-25 years: results from a randomized controlled trial. Int J Cancer (2014) 0.89
Up-regulation of fibronectin in oesophageal squamous cell carcinoma is associated with activation of the Erk pathway. J Pathol (2005) 0.89
Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes. Biochem J (2010) 0.88
Minocycline and doxycycline, but not other tetracycline-derived compounds, protect liver cells from chemical hypoxia and ischemia/reperfusion injury by inhibition of the mitochondrial calcium uniporter. Toxicol Appl Pharmacol (2013) 0.88
Hypoglycemia from IGF2 overexpression associated with activation of fetal promoters and loss of imprinting in a metastatic hemangiopericytoma. J Clin Endocrinol Metab (2009) 0.87
PPARalpha-mediated upregulation of uncoupling protein-2 switches cyanide-induced apoptosis to necrosis in primary cortical cells. Toxicol Sci (2006) 0.86
[Association between high-risk human papillomavirus DNA load and different histological grades of cervical neoplasia]. Zhonghua Yu Fang Yi Xue Za Zhi (2009) 0.86
Effects of RNAi-mediated matrix metalloproteinase-2 gene silencing on the invasiveness and adhesion of esophageal carcinoma cells, KYSE150. Dig Dis Sci (2011) 0.86
Distribution of cervical intraepithelial neoplasia 2, 3 and cancer on the uterine cervix. J Low Genit Tract Dis (2006) 0.86
Correlates, stability and predictors of borderline personality disorder among previously suicidal youth. Eur Child Adolesc Psychiatry (2014) 0.86
Regulation of growth hormone expression by Delta-like protein 1 (Dlk1). Mol Cell Endocrinol (2007) 0.85
High level of proteinuria during treatment with renin-angiotensin inhibitors is a strong predictor of renal outcome in nondiabetic kidney disease. J Clin Pharmacol (2010) 0.85
Receptor internalization-independent activation of Smad2 in activin signaling. Mol Endocrinol (2004) 0.85
MicroRNA218 inhibits glioma migration and invasion via inhibiting glioma-associated oncogene homolog 1 expression at N terminus. Tumour Biol (2013) 0.85
The impact of age at transfer from pediatric to adult-oriented care on renal allograft survival. Pediatr Transplant (2011) 0.85
Dickkopf-1 is involved in invasive growth of esophageal cancer cells. J Mol Histol (2011) 0.84
Six-year regression and progression of cervical lesions of different human papillomavirus viral loads in varied histological diagnoses. Int J Gynecol Cancer (2013) 0.84
Use of serum circulating CCNB2 in cancer surveillance. Int J Biol Markers (2010) 0.84