Published in Eur J Neurosci on October 01, 2002
Inflammation is detrimental for neurogenesis in adult brain. Proc Natl Acad Sci U S A (2003) 5.09
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell (2010) 4.30
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med (2004) 2.86
Spatial learning depends on both the addition and removal of new hippocampal neurons. PLoS Biol (2007) 2.27
Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma. Cell Death Dis (2013) 0.91
Caspase inhibitor infusion protects an avian song control circuit from seasonal-like neurodegeneration. J Neurosci (2008) 0.87
Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia. Mol Neurodegener (2012) 0.86
Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus (2010) 0.83
Expression of neurogenesis genes in human temporal lobe epilepsy with hippocampal sclerosis. Int J Physiol Pathophysiol Pharmacol (2010) 0.78
Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med (2002) 10.10
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat Med (2008) 6.90
Regulation of autophagy by cytoplasmic p53. Nat Cell Biol (2008) 5.97
Inflammation is detrimental for neurogenesis in adult brain. Proc Natl Acad Sci U S A (2003) 5.09
Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A (2011) 4.81
Persistent production of neurons from adult brain stem cells during recovery after stroke. Stem Cells (2005) 2.88
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med (2004) 2.86
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat Neurosci (2009) 2.74
New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell (2008) 2.61
Research in motion: the enigma of Parkinson's disease pathology spread. Nat Rev Neurosci (2008) 2.51
Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability. Neuron (2006) 2.38
Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J Neurosci (2005) 2.32
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions. Cell Rep (2012) 2.31
Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis (2008) 2.26
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain (2005) 2.06
Long-term neuroblast migration along blood vessels in an area with transient angiogenesis and increased vascularization after stroke. Stroke (2007) 1.98
Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res (2011) 1.91
Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis. J Neurosci (2006) 1.91
Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia. J Neurochem (2006) 1.87
Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia (2009) 1.86
Mitochondrial membrane permeabilization in neuronal injury. Nat Rev Neurosci (2009) 1.85
Neurogenesis after ischaemic brain insults. Curr Opin Neurobiol (2003) 1.80
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants. Sci Transl Med (2010) 1.78
Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovasc Dis (2006) 1.75
Isoflurane anesthesia induced persistent, progressive memory impairment, caused a loss of neural stem cells, and reduced neurogenesis in young, but not adult, rodents. J Cereb Blood Flow Metab (2010) 1.75
Dyskinesias following neural transplantation in Parkinson's disease. Nat Neurosci (2002) 1.74
Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species. Prog Neurobiol (2013) 1.69
Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy. Pediatrics (2009) 1.62
Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice. Behav Brain Res (2005) 1.56
Cross-talk between neural stem cells and immune cells: the key to better brain repair? Nat Neurosci (2012) 1.55
Interleukin-18 involvement in hypoxic-ischemic brain injury. J Neurosci (2002) 1.52
Cardiac myosin-binding protein C: a potential early biomarker of myocardial injury. Basic Res Cardiol (2015) 1.52
Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res (2008) 1.50
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia. J Exp Med (2007) 1.50
Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci U S A (2008) 1.48
Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain. J Neurochem (2003) 1.48
Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease. Mov Disord (2010) 1.47
Long-term assessment of striatal dopamine transporters in Parkinsonian patients with intrastriatal embryonic mesencephalic grafts. Eur J Nucl Med Mol Imaging (2006) 1.46
A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire. Int J Oncol (2012) 1.44
Collagen degradation in the abdominal aneurysm: a conspiracy of matrix metalloproteinase and cysteine collagenases. Am J Pathol (2007) 1.43
Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia. J Cereb Blood Flow Metab (2004) 1.40
No evidence for new dopaminergic neurons in the adult mammalian substantia nigra. Proc Natl Acad Sci U S A (2004) 1.39
Stroke-induced neurogenesis in aged brain. Stroke (2005) 1.38
Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J Neurosci (2009) 1.37
Inflammation regulates functional integration of neurons born in adult brain. J Neurosci (2008) 1.35
Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury. J Neurosci (2009) 1.35
Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain. Stem Cells (2012) 1.34
Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium. Arthritis Rheum (2002) 1.34
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. J Virol (2007) 1.33
Life with or without AIF. Trends Biochem Sci (2010) 1.32
Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning. Neurobiol Aging (2005) 1.31
Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice. J Clin Invest (2008) 1.29
MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol Cell Neurosci (2008) 1.29
Differential recovery of neural stem cells in the subventricular zone and dentate gyrus after ionizing radiation. Stem Cells (2009) 1.28
Regulation of stem cell therapies under attack in Europe: for whom the bell tolls. EMBO J (2013) 1.28
Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia. J Neurosci (2006) 1.28
The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. Diabetes (2012) 1.27
Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain. J Cereb Blood Flow Metab (2010) 1.24
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages. J Biol Chem (2004) 1.24
The role of cathepsin B and cystatin C in the mechanisms of invasion by ovarian cancer. Gynecol Oncol (2004) 1.23
Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling. Lancet Neurol (2009) 1.23
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity. Eur J Neurosci (2006) 1.22
Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats. Stroke (2006) 1.18
Age-dependent sensitivity of the developing brain to irradiation is correlated with the number and vulnerability of progenitor cells. J Neurochem (2005) 1.18
Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Mol Cancer Res (2007) 1.18
Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio. Mov Disord (2011) 1.14
Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells. J Cereb Blood Flow Metab (2011) 1.14
Efficient induction of functional neurons from adult human fibroblasts. Cell Cycle (2011) 1.12
Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice. Neurobiol Dis (2005) 1.12
IGF-I neuroprotection in the immature brain after hypoxia-ischemia, involvement of Akt and GSK3beta? Eur J Neurosci (2005) 1.12
Health-related quality of life in multiple system atrophy. Mov Disord (2006) 1.11
Ultrastructural and antigenic properties of neural stem cells and their progeny in adult rat subventricular zone. Glia (2009) 1.11
Grafted neural stem cells develop into functional pyramidal neurons and integrate into host cortical circuitry. Proc Natl Acad Sci U S A (2002) 1.11
Electroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment. Eur J Neurosci (2002) 1.11
Regulation of stroke-induced neurogenesis in adult brain--recent scientific progress. Cereb Cortex (2006) 1.10
Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease. Neurodegener Dis (2012) 1.10
Human fetal cortical and striatal neural stem cells generate region-specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats. J Neurosci Res (2006) 1.10
Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery. Brain (2013) 1.09
Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation. Eur J Neurosci (2006) 1.07
Clinical application of stem cell therapy in Parkinson's disease. BMC Med (2012) 1.07
Imbalance between cysteine proteases and inhibitors in a baboon model of bronchopulmonary dysplasia. Am J Respir Crit Care Med (2005) 1.07
Human cathepsin S, but not cathepsin L, degrades efficiently MHC class II-associated invariant chain in nonprofessional APCs. Proc Natl Acad Sci U S A (2003) 1.06
Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain. J Cereb Blood Flow Metab (2002) 1.06
Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model. PLoS One (2011) 1.06
Sensitization to the lysosomal cell death pathway upon immortalization and transformation. Cancer Res (2004) 1.05
Abeta immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice. J Neurosci (2009) 1.05
Suppression of stroke-induced progenitor proliferation in adult subventricular zone by tumor necrosis factor receptor 1. J Cereb Blood Flow Metab (2008) 1.05
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest (2003) 1.04
Effects of allopurinol and deferoxamine on reperfusion injury of the brain in newborn piglets after neonatal hypoxia-ischemia. Pediatr Res (2003) 1.03
TNF-alpha antibody infusion impairs survival of stroke-generated neuroblasts in adult rat brain. Exp Neurol (2005) 1.03
Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury. Am J Pathol (2008) 1.03
Activation of ERK1/2 after neonatal rat cerebral hypoxia-ischaemia. J Neurochem (2003) 1.03
Neuronal apoptosis after brief and prolonged seizures. Prog Brain Res (2002) 1.03
Status epilepticus severity influences the long-term outcome of neurogenesis in the adult dentate gyrus. Neurobiol Dis (2004) 1.02
Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats. Neurobiol Dis (2012) 1.02
Less neurogenesis and inflammation in the immature than in the juvenile brain after cerebral hypoxia-ischemia. J Cereb Blood Flow Metab (2006) 1.02
Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts. Sci Transl Med (2012) 1.02
Invariant chain controls the activity of extracellular cathepsin L. J Exp Med (2002) 1.02
Sex-dependent differences in behavior and hippocampal neurogenesis after irradiation to the young mouse brain. Eur J Neurosci (2012) 1.00