Published in JAMA on November 06, 2002
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Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice. Gastroenterology (2009) 1.07
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Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in patients with chronic pancreatitis. Hum Mutat (2015) 0.83
Idiopathic vs hereditary pancreatitis. JAMA (2003) 0.80
Is it necessary to distinguish between alcoholic and nonalcoholic chronic pancreatitis? J Gastroenterol (2007) 0.77
Extensive molecular analysis suggested the strong genetic heterogeneity of idiopathic chronic pancreatitis. Mol Med (2016) 0.76
Idiopathic vs hereditary pancreatitis. JAMA (2003) 0.75
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial. JAMA (2010) 6.65
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA (2013) 3.15
Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol (2004) 2.82
Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. J Biol Chem (2002) 2.67
Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis. Gut (2012) 2.52
Natural radioactivity and human mitochondrial DNA mutations. Proc Natl Acad Sci U S A (2002) 2.46
Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept. Lab Invest (2002) 2.33
Autoimmune pancreatitis in MRL/Mp mice is a T cell-mediated disease responsive to cyclosporine A and rapamycin treatment. Gut (2013) 2.28
Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res (2003) 2.08
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nat Genet (2005) 2.04
Endoscopic retrograde cholangiopancreatography, intraductal ultrasonography, and magnetic resonance cholangiopancreatography in bile duct strictures: a prospective comparison of imaging diagnostics with histopathological correlation. Am J Gastroenterol (2004) 1.96
Double balloon enteroscopy: a useful tool for diagnostic and therapeutic procedures in the pancreaticobiliary system. Am J Gastroenterol (2008) 1.92
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis. Nat Genet (2006) 1.90
Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma. Cancer Res (2007) 1.87
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Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer. Gastroenterology (2009) 1.75
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Total pancreatectomy and islet autotransplantation in chronic pancreatitis: recommendations from PancreasFest. Pancreatology (2013) 1.67
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Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet (2012) 1.63
Inverse association between serum free thyroxine levels and hepatic steatosis: results from the Study of Health in Pomerania. Thyroid (2012) 1.62
Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis. J Biol Chem (2002) 1.59
Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice. Gut (2011) 1.58
Usual ductal hyperplasia of the breast is a committed stem (progenitor) cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in situ. J Pathol (2002) 1.56
Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism. Hum Mutat (2009) 1.56
Undifferentiated embryonal sarcoma of the liver in adults. Cancer (2008) 1.56
Why does pancreatic overstimulation cause pancreatitis? Annu Rev Physiol (2007) 1.56
Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus. Hepatology (2013) 1.53
A randomized, community-based trial of home visiting to reduce blood lead levels in children. Pediatrics (2006) 1.51
Recent understanding of IBD pathogenesis: implications for future therapies. Inflamm Bowel Dis (2006) 1.51
Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document. Pancreas (2010) 1.49
Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model. BMC Cancer (2009) 1.47
Independent risk factors for gallstone formation in a region with high cholelithiasis prevalence. Digestion (2005) 1.46
Single-step versus multi-step transmural drainage of pancreatic pseudocysts: the use of cystostome is effective and timesaving. Scand J Gastroenterol (2011) 1.45
FREM1 mutations cause bifid nose, renal agenesis, and anorectal malformations syndrome. Am J Hum Genet (2009) 1.41
Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches. Eur J Immunol (2002) 1.40
Measurement of Resource Utilization for Total and Reverse Shoulder Arthroplasty. Am J Orthop (Belle Mead NJ) (2015) 1.40
Head covering and the risk for SIDS: findings from the New Zealand and German SIDS case-control studies. Pediatrics (2008) 1.40
International Journal of Legal Medicine's manuscript submission and peer-review system goes electronic! Int J Legal Med (2009) 1.38
p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem (2003) 1.35
Endocytotic segregation of gliadin peptide 31-49 in enterocytes. Gut (2009) 1.34
Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. Am J Physiol Gastrointest Liver Physiol (2005) 1.33
Diagnosis and treatment of pancreatic pseudocysts in chronic pancreatitis. Pancreas (2008) 1.29
Absence of CCR6 inhibits CD4+ regulatory T-cell development and M-cell formation inside Peyer's patches. Am J Pathol (2005) 1.29
Sleep environment risk factors for sudden infant death syndrome: the German Sudden Infant Death Syndrome Study. Pediatrics (2009) 1.27
The EDNAP mitochondrial DNA population database (EMPOP) collaborative exercises: organisation, results and perspectives. Forensic Sci Int (2004) 1.26
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen. J Biol Chem (2001) 1.25
Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer (2009) 1.25
Trypsin activity is not involved in premature, intrapancreatic trypsinogen activation. Am J Physiol Gastrointest Liver Physiol (2002) 1.24
Pancreatic pseudocysts--when and how to treat? HPB (Oxford) (2006) 1.21
In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model. BMC Cancer (2011) 1.21
Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document. Pancreatology (2011) 1.20
The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. Gastroenterology (2011) 1.19
Human intestinal microvascular endothelial cells express Toll-like receptor 5: a binding partner for bacterial flagellin. J Immunol (2004) 1.19
Endoluminal gastroplasty (EndoCinch) versus endoscopic polymer implantation (Enteryx) for treatment of gastroesophageal reflux disease: 6-month results of a prospective, randomized trial. Am J Gastroenterol (2006) 1.19
Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma. Int J Cancer (2012) 1.18
Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction. J Biol Chem (2003) 1.16
Drug-induced pancreatitis. Curr Gastroenterol Rep (2012) 1.16
The lymphotoxin-beta receptor is critical for control of murine Citrobacter rodentium-induced colitis. Gastroenterology (2004) 1.15
Modifiable risk factors for SIDS in Germany: results of GeSID. Acta Paediatr (2005) 1.15
Characterization of tissue oxygen saturation and the vascular occlusion test: influence of measurement sites, probe sizes and deflation thresholds. Crit Care (2009) 1.14
Animal models for investigating chronic pancreatitis. Fibrogenesis Tissue Repair (2011) 1.14
Induction of colitis in mice deficient of Peyer's patches and mesenteric lymph nodes is associated with increased disease severity and formation of colonic lymphoid patches. Am J Pathol (2002) 1.13
Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats. Gastroenterology (2005) 1.11
Recent advances in autoimmune pancreatitis: type 1 and type 2. Gut (2013) 1.10
Early detection of sporadic pancreatic cancer: summative review. Pancreas (2015) 1.10
Beyond gastric acid reduction: proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells. Biochem Biophys Res Commun (2006) 1.10
Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice. Gut (2012) 1.09
Mycobacterium avium subsp. paratuberculosis infection in a patient with HIV, Germany. Emerg Infect Dis (2002) 1.08
Y-chromosomal microsatellite mutation rates in a population sample from northwestern Germany. Int J Legal Med (2006) 1.07
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice. Gastroenterology (2009) 1.07
Angiopoietin-2, a regulator of vascular permeability in inflammation, is associated with persistent organ failure in patients with acute pancreatitis from the United States and Germany. Am J Gastroenterol (2010) 1.06
Vascular smooth muscle and nitric oxide synthase. FASEB J (2002) 1.05
Reference ranges of serum IGF-1 and IGFBP-3 levels in a general adult population: results of the Study of Health in Pomerania (SHIP). Growth Horm IGF Res (2007) 1.05
The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts. J Cell Physiol (2008) 1.05
Prevalence, associations, and trends of biliary-tract candidiasis: a prospective observational study. Gastrointest Endosc (2009) 1.04
Investigation of living pancreas tumor cells by digital holographic microscopy. J Biomed Opt (2006) 1.04
Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men. Int J Androl (2009) 1.04
Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice. Am J Pathol (2009) 1.04