Published in Infect Immun on December 01, 2002
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc Natl Acad Sci U S A (2007) 2.46
Pathogenesis and pathophysiology of pneumococcal meningitis. Clin Microbiol Rev (2011) 1.87
Listeria monocytogenes surface proteins: from genome predictions to function. Microbiol Mol Biol Rev (2007) 1.59
Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. J Clin Invest (2011) 1.53
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. PLoS Pathog (2007) 1.45
Clostridium difficile infection: toxins and non-toxin virulence factors, and their contributions to disease establishment and host response. Gut Microbes (2012) 1.33
Structure and metal-dependent mechanism of peptidoglycan deacetylase, a streptococcal virulence factor. Proc Natl Acad Sci U S A (2005) 1.31
Differential proteomic analysis of the Bacillus anthracis secretome: distinct plasmid and chromosome CO2-dependent cross talk mechanisms modulate extracellular proteolytic activities. J Bacteriol (2006) 1.28
LambdaSa1 and LambdaSa2 prophage lysins of Streptococcus agalactiae. Appl Environ Microbiol (2007) 1.25
Modifications to the peptidoglycan backbone help bacteria to establish infection. Infect Immun (2010) 1.22
Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics. Infect Immun (2013) 1.17
Clostridium difficile has an original peptidoglycan structure with a high level of N-acetylglucosamine deacetylation and mainly 3-3 cross-links. J Biol Chem (2011) 1.17
Oxidative stress-induced peptidoglycan deacetylase in Helicobacter pylori. J Biol Chem (2009) 1.13
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. PLoS Pathog (2008) 1.11
Peptidoglycan deacetylation in Helicobacter pylori contributes to bacterial survival by mitigating host immune responses. Infect Immun (2010) 1.05
Role of the lysozyme inhibitor Ivy in growth or survival of Escherichia coli and Pseudomonas aeruginosa bacteria in hen egg white and in human saliva and breast milk. Appl Environ Microbiol (2008) 1.05
Bacterial peptidoglycan degrading enzymes and their impact on host muropeptide detection. J Innate Immun (2009) 1.04
The extracytoplasmic function sigma factor SigV plays a key role in the original model of lysozyme resistance and virulence of Enterococcus faecalis. PLoS One (2010) 1.04
Use of selective capture of transcribed sequences to identify genes preferentially expressed by Streptococcus suis upon interaction with porcine brain microvascular endothelial cells. Appl Environ Microbiol (2007) 1.01
The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology (2009) 0.99
The Enterococcus faecalis sigV protein is an extracytoplasmic function sigma factor contributing to survival following heat, acid, and ethanol treatments. J Bacteriol (2005) 0.94
Both TLR2 and TRIF contribute to interferon-β production during Listeria infection. PLoS One (2012) 0.92
Cationic antimicrobial peptide resistance mechanisms of streptococcal pathogens. Biochim Biophys Acta (2015) 0.91
O-Acetylation of sialic acid on Group B Streptococcus inhibits neutrophil suppression and virulence. Biochem J (2010) 0.91
Eep confers lysozyme resistance to enterococcus faecalis via the activation of the extracytoplasmic function sigma factor SigV. J Bacteriol (2013) 0.90
The capsule sensitizes Streptococcus pneumoniae to alpha-defensins human neutrophil proteins 1 to 3. Infect Immun (2008) 0.85
Streptococcus mutans SMU.623c codes for a functional, metal-dependent polysaccharide deacetylase that modulates interactions with salivary agglutinin. J Bacteriol (2008) 0.85
CpsY influences Streptococcus iniae cell wall adaptations important for neutrophil intracellular survival. Infect Immun (2012) 0.84
Identification and characterization of a novel polysaccharide deacetylase C (PdaC) from Bacillus subtilis. J Biol Chem (2012) 0.84
Role of DLP12 lysis genes in Escherichia coli biofilm formation. Microbiology (2011) 0.82
Antimicrobial Peptide Resistance Mechanisms of Gram-Positive Bacteria. Antibiotics (Basel) (2014) 0.82
Structural and functional characterization of a putative polysaccharide deacetylase of the human parasite Encephalitozoon cuniculi. Protein Sci (2009) 0.81
Mycobacterium tuberculosis Rv1096 protein: gene cloning, protein expression, and peptidoglycan deacetylase activity. BMC Microbiol (2014) 0.78
Structure determination of BA0150, a putative polysaccharide deacetylase from Bacillus anthracis. Acta Crystallogr F Struct Biol Commun (2014) 0.76
Envelope Structures of Gram-Positive Bacteria. Curr Top Microbiol Immunol (2016) 0.76
Identification of CiaR Regulated Genes That Promote Group B Streptococcal Virulence and Interaction with Brain Endothelial Cells. PLoS One (2016) 0.75
Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase. Biochemistry (2016) 0.75
Accumulation of Peptidoglycan O-Acetylation Leads to Altered Cell Wall Biochemistry and Negatively Impacts Pathogenesis Factors of Campylobacter jejuni. J Biol Chem (2016) 0.75
Comparative Genomics of Carriage and Disease Isolates of Streptococcus pneumoniae Serotype 22F Reveals Lineage-Specific Divergence and Niche Adaptation. Genome Biol Evol (2016) 0.75
Inhibition of Staphylococcus aureus Cell Wall Biosynthesis by Desleucyl-Oritavancin: a Quantitative Peptidoglycan Composition Analysis by Mass Spectrometry. J Bacteriol (2017) 0.75
Study of lysozyme resistance in Rhodococcus equi. Curr Microbiol (2013) 0.75
From bacterial killing to immune modulation: Recent insights into the functions of lysozyme. PLoS Pathog (2017) 0.75
Structure and function of a broad-specificity chitin deacetylase from Aspergillus nidulans FGSC A4. Sci Rep (2017) 0.75
Analysis of peptidoglycan structure from vegetative cells of Bacillus subtilis 168 and role of PBP 5 in peptidoglycan maturation. J Bacteriol (1999) 2.43
The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae. J Biol Chem (2000) 2.19
Enzymatic deacetylation of N-acetylglucosamine residues in peptidoglycan from Bacillus cereus cell walls. Biochem Biophys Res Commun (1971) 1.35
Possible role of a choline-containing teichoic acid in the maintenance of normal cell shape and physiology in Streptococcus oralis. J Bacteriol (1993) 1.30
The action of lysozyme on peptidoglycan with N-unsubstituted glucosamine residues. Isolation of glycan fragments and their susceptibility to lysozyme. Eur J Biochem (1977) 1.18
Effects of lysozyme on Bacillus cereus 569: rupture of chains of bacteria and enhancement of sensitivity to autolysins. J Gen Microbiol (1979) 1.16
Triggering of pneumococcal autolysis by lysozyme. J Infect Dis (1993) 1.03
Cerebrospinal fluid lysozyme in bacterial and viral meningitis. Acta Med Scand (1978) 1.03
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
Rapid pneumococcal evolution in response to clinical interventions. Science (2011) 9.09
Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus. Lancet Infect Dis (2002) 6.18
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proc Natl Acad Sci U S A (2007) 6.14
Tackling antibiotic resistance. Nat Rev Microbiol (2011) 3.95
Overexpression of genes of the cell wall stimulon in clinical isolates of Staphylococcus aureus exhibiting vancomycin-intermediate- S. aureus-type resistance to vancomycin. J Bacteriol (2006) 2.32
Alternative mutational pathways to intermediate resistance to vancomycin in methicillin-resistant Staphylococcus aureus. J Infect Dis (2013) 2.19
International clones of methicillin-resistant Staphylococcus aureus in two hospitals in Miami, Florida. J Clin Microbiol (2004) 1.94
Antibiotic resistant Staphylococcus aureus: a paradigm of adaptive power. Curr Opin Microbiol (2007) 1.93
Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and cell wall cross-linking of Staphylococcus aureus: evidence for the cooperative functioning of PBP2, PBP4, and PBP2A. J Bacteriol (2005) 1.83
Wide geographic distribution of a unique methicillin-resistant Staphylococcus aureus clone in Hungarian hospitals. Clin Microbiol Infect (1997) 1.65
Properties of a novel PBP2A protein homolog from Staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype. J Biol Chem (2012) 1.59
Guidelines for reporting novel mecA gene homologues. Antimicrob Agents Chemother (2012) 1.54
Inactivation of the srtA gene affects localization of surface proteins and decreases adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro. Infect Immun (2003) 1.51
Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300. PLoS Pathog (2012) 1.44
High level oxacillin and vancomycin resistance and altered cell wall composition in Staphylococcus aureus carrying the staphylococcal mecA and the enterococcal vanA gene complex. J Biol Chem (2003) 1.42
Development of methicillin resistance in clinical isolates of Staphylococcus sciuri by transcriptional activation of the mecA homologue native to s. J Bacteriol (2003) 1.32
Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan. J Biol Chem (2007) 1.31
Requirements of peptidoglycan structure that allow detection by the Drosophila Toll pathway. EMBO Rep (2005) 1.30
Attenuation of penicillin resistance in a peptidoglycan O-acetyl transferase mutant of Streptococcus pneumoniae. Mol Microbiol (2006) 1.26
Extensive and genome-wide changes in the transcription profile of Staphylococcus aureus induced by modulating the transcription of the cell wall synthesis gene murF. J Bacteriol (2006) 1.23
Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor. Structure (2002) 1.18
Penicillin-binding protein 2 is essential for expression of high-level vancomycin resistance and cell wall synthesis in vancomycin-resistant Staphylococcus aureus carrying the enterococcal vanA gene complex. Antimicrob Agents Chemother (2004) 1.18
Inhibition of the autolytic system by vancomycin causes mimicry of vancomycin-intermediate Staphylococcus aureus-type resistance, cell concentration dependence of the MIC, and antibiotic tolerance in vancomycin-susceptible S. aureus. Antimicrob Agents Chemother (2006) 1.18
Mechanisms of vancomycin resistance in Staphylococcus aureus. J Clin Invest (2014) 1.15
Fluorescence ratio imaging microscopy shows decreased access of vancomycin to cell wall synthetic sites in vancomycin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2007) 1.14
Whole-genome sequencing reveals a link between β-lactam resistance and synthetases of the alarmone (p)ppGpp in Staphylococcus aureus. Microb Drug Resist (2013) 1.14
The murMN operon: a functional link between antibiotic resistance and antibiotic tolerance in Streptococcuspneumoniae. Proc Natl Acad Sci U S A (2002) 1.12
Isolation and analysis of cell wall components from Streptococcus pneumoniae. Anal Biochem (2011) 1.10
Drastic reduction in the virulence of Streptococcus pneumoniae expressing type 2 capsular polysaccharide but lacking choline residues in the cell wall. Mol Microbiol (2006) 1.07
Identification of genetic determinants and enzymes involved with the amidation of glutamic acid residues in the peptidoglycan of Staphylococcus aureus. PLoS Pathog (2012) 1.06
Pilot study of the genetic diversity of the pneumococcal nasopharyngeal flora among children attending day care centers. J Clin Microbiol (2002) 1.06
A link in transcription between the native pbpB and the acquired mecA gene in a strain of Staphylococcus aureus. Microbiology (2006) 1.05
Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone. BMC Biol (2014) 1.03
Evidence for a dual role of PBP1 in the cell division and cell separation of Staphylococcus aureus. Mol Microbiol (2009) 1.00
Perturbation of cell wall synthesis suppresses autolysis in Staphylococcus aureus: evidence for coregulation of cell wall synthetic and hydrolytic enzymes. J Bacteriol (2007) 0.99
Penicillin-binding proteins and cell wall composition in beta-lactam-sensitive and -resistant strains of Staphylococcus sciuri. J Bacteriol (2007) 0.98
Comparative study of the susceptibilities of major epidemic clones of methicillin-resistant Staphylococcus aureus to oxacillin and to the new broad-spectrum cephalosporin ceftobiprole. Antimicrob Agents Chemother (2008) 0.97
Reconstruction of the phenotypes of methicillin-resistant Staphylococcus aureus by replacement of the staphylococcal cassette chromosome mec with a plasmid-borne copy of Staphylococcus sciuri pbpD gene. Antimicrob Agents Chemother (2008) 0.95
In vivo capsular switch in Streptococcus pneumoniae--analysis by whole genome sequencing. PLoS One (2012) 0.95
The challenge of antibiotic resistant bacterial pathogens: the medical need, the market and prospects for new antimicrobial agents. Curr Opin Microbiol (2004) 0.94
The essential tacF gene is responsible for the choline-dependent growth phenotype of Streptococcus pneumoniae. J Bacteriol (2007) 0.94
Diversity of penicillin-nonsusceptible Streptococcus pneumoniae circulating in Iceland after the introduction of penicillin-resistant clone Spain(6B)-2. J Infect Dis (2002) 0.91
The structure of the cell wall peptidoglycan of Bacillus cereus RSVF1, a strain closely related to Bacillus anthracis. Microb Drug Resist (2004) 0.91
Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. PLoS One (2011) 0.89
EURISWEB--Web-based epidemiological surveillance of antibiotic-resistant pneumococci in day care centers. BMC Med Inform Decis Mak (2003) 0.89
Serotypes and clonal types of penicillin-susceptible streptococcus pneumoniae causing invasive disease in children in five Latin American countries. Microb Drug Resist (2005) 0.88
High-level (beta)-lactam resistance and cell wall synthesis catalyzed by the mecA homologue of Staphylococcus sciuri introduced into Staphylococcus aureus. J Bacteriol (2005) 0.85
Different pathways of choline metabolism in two choline-independent strains of Streptococcus pneumoniae and their impact on virulence. J Bacteriol (2008) 0.85
Expression of high-level methicillin resistance in Staphylococcus aureus from the Staphylococcus sciuri mec A homologue: role of mutation(s) in the genetic background and in the coding region of mec A. Microb Drug Resist (2005) 0.85
Cell wall branches, penicillin resistance and the secrets of the MurM protein. Trends Microbiol (2003) 0.84
A multinational workshop on drug-resistant pathogens of the respiratory tract: prevalence, risk factors and intervention strategies. Clin Microbiol Infect (1999) 0.83
The glucosaminidase domain of Atl - the major Staphylococcus aureus autolysin - has DNA-binding activity. Microbiologyopen (2014) 0.82
Recurrent furunculosis caused by a community-acquired Staphylococcus aureus strain belonging to the USA300 clone. Microb Drug Resist (2015) 0.81
X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus. Proteins (2003) 0.81
Role of a sodium-dependent symporter homologue in the thermosensitivity of beta-lactam antibiotic resistance and cell wall composition in Staphylococcus aureus. Antimicrob Agents Chemother (2007) 0.80
Carriage and antibiotic resistance of respiratory pathogens and molecular epidemiology of antibiotic-resistant Streptococcus pneumoniae colonizing children in day-care centers in Lisbon: the Portuguese day-care center initiative. Clin Microbiol Infect (1999) 0.80
Virulence potential and genome-wide characterization of drug resistant Streptococcus pneumoniae clones selected in vivo by the 7-valent pneumococcal conjugate vaccine. PLoS One (2013) 0.78
Role of teichoic acid choline moieties in the virulence of Streptococcus pneumoniae. Infect Immun (2009) 0.77
The CEM-NET initiative: molecular biology and epidemiology in alliance--tracking antibiotic-resistant staphylococci and pneumococci in hospitals and in the community. Int J Med Microbiol (2011) 0.77
From the Bench to the Barbershop: Community Engagement to Raise Awareness About Community-Acquired Methicillin-Resistant <i>Staphylococcus aureus</i> and Hepatitis C Virus Infection. Prog Community Health Partnersh (2016) 0.75
Antimicrobials. Curr Opin Microbiol (2010) 0.75