Published in JAMA on November 27, 2002
Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. JAMA (2015) 3.32
Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA (2005) 3.21
A multicenter randomized trial of computer-driven protocolized weaning from mechanical ventilation. Am J Respir Crit Care Med (2006) 2.45
State Behavioral Scale: a sedation assessment instrument for infants and young children supported on mechanical ventilation. Pediatr Crit Care Med (2006) 2.26
Weaning and extubation readiness in pediatric patients. Pediatr Crit Care Med (2009) 2.00
Covariate adjustment in randomized trials with binary outcomes: targeted maximum likelihood estimation. Stat Med (2009) 1.70
The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med (2008) 1.60
No child left behind: Enrolling children and adults simultaneously in critical care randomized trials. Crit Care Med (2009) 1.56
Prone positioning can be safely performed in critically ill infants and children. Pediatr Crit Care Med (2006) 1.46
Clinical Epidemiology of Extubation Failure in the Pediatric Cardiac ICU: A Report From the Pediatric Cardiac Critical Care Consortium. Pediatr Crit Care Med (2015) 1.46
NICU bedside caregivers sustain process improvement and decrease incidence of bronchopulmonary dysplasia in infants < 30 weeks gestation. Respir Care (2014) 1.40
Clinical trial design--effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome. J Crit Care (2006) 1.25
Pediatric extubation readiness tests should not use pressure support. Intensive Care Med (2016) 1.20
Potential covariates that affect post-extubation breathing effort in children. Intensive Care Med (2016) 1.06
Surfactant therapy for acute lung injury and acute respiratory distress syndrome. Crit Care Clin (2011) 1.04
Validity and generalizability of the Withdrawal Assessment Tool-1 (WAT-1) for monitoring iatrogenic withdrawal syndrome in pediatric patients. Pain (2011) 0.99
The design of future pediatric mechanical ventilation trials for acute lung injury. Am J Respir Crit Care Med (2010) 0.99
Measurement of maximal inspiratory pressure in ventilated children. Pediatr Pulmonol (2008) 0.96
Delirium: an emerging frontier in the management of critically ill children. Crit Care Clin (2009) 0.95
Surfactant for pediatric acute lung injury. Pediatr Clin North Am (2008) 0.94
Outcome of paediatric intensive care survivors. Eur J Pediatr (2007) 0.91
Does taking endurance into account improve the prediction of weaning outcome in mechanically ventilated children? Crit Care (2005) 0.89
Pediatric Sepsis - Part I: "Children are not small adults!" Open Inflamm J (2011) 0.87
Application of Burn's wean assessment program on the duration of mechanical ventilation among patients in intensive care units: A clinical trial. Iran J Nurs Midwifery Res (2012) 0.86
Development and implementation of explicit computerized protocols for mechanical ventilation in children. Ann Intensive Care (2011) 0.86
Protocols to improve the care of critically ill pediatric and adult patients. JAMA (2002) 0.85
Symbolic dynamic analysis of relations between cardiac and breathing cycles in patients on weaning trials. Ann Biomed Eng (2010) 0.82
Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants. Crit Care (2013) 0.81
Closed loop mechanical ventilation. J Clin Monit Comput (2013) 0.80
Bench-to-bedside review: Ventilator strategies to reduce lung injury -- lessons from pediatric and neonatal intensive care. Crit Care (2004) 0.79
Prediction of ventilation weaning outcome: children are not little adults. Crit Care (2005) 0.77
Automatic Tube Compensation versus Pressure Support Ventilation and Extubation Outcome in Children: A Randomized Controlled Study. ISRN Pediatr (2013) 0.75
Nurses and ventilators. Crit Care (2012) 0.75
Sedation in Critically Ill Children with Respiratory Failure. Front Pediatr (2016) 0.75
Invasive ventilation modes in children: a systematic review and meta-analysis. Crit Care (2011) 0.75
Relevant Outcomes in Pediatric Acute Respiratory Distress Syndrome Studies. Front Pediatr (2016) 0.75
A Pediatric Intensive Care Unit Bedside Computer Clinical Decision Support Protocol for Hyperglycemia Is Feasible, Safe and Offers Advantages. Diabetes Technol Ther (2017) 0.75
Recent Advances in Pediatric Ventilatory Assistance. F1000Res (2017) 0.75
Investigating the Impacts of Preoperative Steroid Treatment on Tumor Necrosis Factor-Alpha and Duration of Extubation Time underwent Ventricular Septal Defect Surgery. Balkan Med J (2016) 0.75
Defining sedation-related adverse events in the pediatric intensive care unit. Heart Lung (2013) 0.75
Evaluation of diaphragmatic function in mechanically ventilated children: An ultrasound study. PLoS One (2017) 0.75
Remifentanil and propofol for weaning of mechanically ventilated pediatric intensive care patients. Eur J Pediatr (2010) 0.75
Unexpected increased mortality after implementation of a commercially sold computerized physician order entry system. Pediatrics (2005) 15.40
Fibromyalgia syndrome in an Amish community: a controlled study to determine disease and symptom prevalence. J Rheumatol (2003) 8.00
Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med (2013) 7.00
Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med (2010) 5.60
Hyponatremia among runners in the Boston Marathon. N Engl J Med (2005) 5.14
Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A (2008) 5.08
Therapeutic hypothermia after out-of-hospital cardiac arrest in children. N Engl J Med (2015) 4.90
Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston Circulatory Arrest Trial. J Thorac Cardiovasc Surg (2003) 3.85
Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med (2012) 3.67
Sentinel node biopsy should be the standard of care for patients with intermediate and thick melanomas. Aust Fam Physician (2015) 3.62
Socioeconomic development as an intervention against malaria: a systematic review and meta-analysis. Lancet (2013) 3.22
Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA (2005) 3.21
Survey of in-house coverage by pediatric intensivists: characterization of 24/7 in-hospital pediatric critical care faculty coverage*. Pediatr Crit Care Med (2014) 3.09
Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study. Lancet (2004) 3.01
Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE review. Am J Epidemiol (2005) 3.00
A randomized clinical trial of the management of esophageal coins in children. Pediatrics (2005) 2.96
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Short report: Piloting paperless data entry for clinical research in Africa. Am J Trop Med Hyg (2005) 2.85
Fellowship training, workload, fatigue and physical stress: a prospective observational study. CMAJ (2004) 2.75
Adolescents with d-transposition of the great arteries corrected with the arterial switch procedure: neuropsychological assessment and structural brain imaging. Circulation (2011) 2.70
Baseline serum concentrations of zinc, selenium, and prolactin in critically ill children. Pediatr Crit Care Med (2013) 2.66
Relationship between funding source and conclusion among nutrition-related scientific articles. PLoS Med (2007) 2.54
Standardized data collection for multi-center clinical studies of severe malaria in African children: establishing the SMAC network. Trans R Soc Trop Med Hyg (2006) 2.52
The feasibility of conducting clinical trials in infants and children with acute respiratory failure. Am J Respir Crit Care Med (2003) 2.48
Functional Status Scale: new pediatric outcome measure. Pediatrics (2009) 2.42
Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. Pediatr Crit Care Med (2013) 2.31
Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol (2006) 2.30
State Behavioral Scale: a sedation assessment instrument for infants and young children supported on mechanical ventilation. Pediatr Crit Care Med (2006) 2.26
Attention and awareness in stage magic: turning tricks into research. Nat Rev Neurosci (2008) 2.18
Early oxygenation and ventilation measurements after pediatric cardiac arrest: lack of association with outcome. Crit Care Med (2013) 2.08
Extracorporeal membrane oxygenation for the support of infants, children, and young adults with acute myocarditis: a review of the Extracorporeal Life Support Organization registry. Crit Care Med (2010) 2.05
Weaning and extubation readiness in pediatric patients. Pediatr Crit Care Med (2009) 2.00
Standardizing postoperative PICU handovers improves handover metrics and patient outcomes. Pediatr Crit Care Med (2015) 1.99
Sexual orientation disparities in longitudinal alcohol use patterns among adolescents: findings from the Growing Up Today Study. Arch Pediatr Adolesc Med (2008) 1.98
Randomized trial of an internet curriculum on herbs and other dietary supplements for health care professionals. Acad Med (2002) 1.94
Complications related to feeding tube placement. Curr Opin Gastroenterol (2007) 1.93
The ideal time interval for critical care severity-of-illness assessment. Pediatr Crit Care Med (2013) 1.91
Disseminated varicella infection due to the vaccine strain of varicella-zoster virus, in a patient with a novel deficiency in natural killer T cells. J Infect Dis (2003) 1.91
Aqueous inorganic inks for low-temperature fabrication of ZnO TFTs. J Am Chem Soc (2008) 1.86
Efficacy outcome selection in the therapeutic hypothermia after pediatric cardiac arrest trials. Pediatr Crit Care Med (2015) 1.82
Active rehabilitation and physical therapy during extracorporeal membrane oxygenation while awaiting lung transplantation: a practical approach. Crit Care Med (2011) 1.80
What influences parents' decisions to limit or withdraw life support? Pediatr Crit Care Med (2005) 1.79
The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. Pediatr Crit Care Med (2012) 1.79
Age-specific fluoride exposure in drinking water and osteosarcoma (United States). Cancer Causes Control (2006) 1.76
Recommendations for probiotic use--2008. J Clin Gastroenterol (2008) 1.76
Critical pertussis illness in children: a multicenter prospective cohort study. Pediatr Crit Care Med (2013) 1.74
An anthropomorphic breast model for breast imaging simulation and optimization. Acad Radiol (2011) 1.73
Active rehabilitation during extracorporeal membrane oxygenation as a bridge to lung transplantation. Respir Care (2012) 1.73
Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure: an evidence-based review of the past decade (2002-2012). Pediatr Crit Care Med (2013) 1.71
Blood transfusion after pediatric cardiac surgery is associated with prolonged hospital stay. Ann Thorac Surg (2011) 1.71
Circumstances surrounding end of life in a pediatric intensive care unit. Pediatrics (2003) 1.70
Impact of a quality improvement program on care and outcomes for children with asthma. Arch Pediatr Adolesc Med (2005) 1.70
The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants. J Thorac Cardiovasc Surg (2003) 1.69
Randomized trial of hematocrit 25% versus 35% during hypothermic cardiopulmonary bypass in infant heart surgery. J Thorac Cardiovasc Surg (2008) 1.69
Mechanical ventilation guided by electrical impedance tomography in experimental acute lung injury. Crit Care Med (2013) 1.68
A National Emergency Airway Registry for children: landscape of tracheal intubation in 15 PICUs. Crit Care Med (2013) 1.68
Hospital volume and neonatal mortality among very low birth weight infants. Pediatrics (2006) 1.67
Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure. Crit Care Med (2012) 1.67
In vitro chloroquine susceptibility and PCR analysis of pfcrt and pfmdr1 polymorphisms in Plasmodium falciparum isolates from Senegal. Am J Trop Med Hyg (2002) 1.66
Long-term effects from a randomized trial of two public health preventive interventions for parental depression. J Fam Psychol (2007) 1.63
Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4, and 8 years. Anesthesiology (2004) 1.61
The endotracheal tube air leak test does not predict extubation outcome in critically ill pediatric patients. Pediatr Crit Care Med (2008) 1.60
Sexual orientation and drug use in a longitudinal cohort study of U.S. adolescents. Addict Behav (2010) 1.58
Rationale and design of the pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. JPEN J Parenter Enteral Nutr (2009) 1.58
Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastroenterology (2010) 1.58
Antenatal corticosteroids trial in preterm births to increase neonatal survival in developing countries: study protocol. Reprod Health (2012) 1.58
Regional lung volume changes in children with acute respiratory distress syndrome during a derecruitment maneuver. Crit Care Med (2007) 1.57
A framework for conducting follow-up meetings with parents after a child's death in the pediatric intensive care unit. Pediatr Crit Care Med (2011) 1.57
End-tidal and arterial carbon dioxide measurements correlate across all levels of physiologic dead space. Respir Care (2010) 1.56
Pressure-controlled ventilation in children with severe status asthmaticus. Pediatr Crit Care Med (2004) 1.56
Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: a tertiary center intensive care unit experience from April to October 2009. Crit Care Med (2010) 1.55
Design and rationale of safe pediatric euglycemia after cardiac surgery: a randomized controlled trial of tight glycemic control after pediatric cardiac surgery. Pediatr Crit Care Med (2013) 1.55
Diarrhoea and effects of different water sources, sanitation and hygiene behaviour in East Africa. Trop Med Int Health (2002) 1.54
Novel method to quantify loss of heart rate variability in pediatric multiple organ failure. Crit Care Med (2003) 1.54
Herbs and other dietary supplements: healthcare professionals' knowledge, attitudes, and practices. Altern Ther Health Med (2003) 1.54
Predictors of shared decision making and level of agreement between consumers and providers in psychiatric care. Community Ment Health J (2013) 1.54
Opioid analgesia in mechanically ventilated children: results from the multicenter Measuring Opioid Tolerance Induced by Fentanyl study. Pediatr Crit Care Med (2013) 1.53
GREIT: a unified approach to 2D linear EIT reconstruction of lung images. Physiol Meas (2009) 1.52
Length of stay after infant heart surgery is related to cognitive outcome at age 8 years. J Pediatr (2003) 1.52
The frequency of cardiac arrests in patients with congenital heart disease undergoing cardiac catheterization. Anesth Analg (2014) 1.51
Fatal and near-fatal asthma in children: the critical care perspective. J Pediatr (2012) 1.51
Quality of life of pediatric cardiac patients who previously required extracorporeal membrane oxygenation. Pediatr Crit Care Med (2012) 1.51
Clinical outcomes of children receiving intensive cardiopulmonary support during hematopoietic stem cell transplant. Pediatr Crit Care Med (2013) 1.50
The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry (2006) 1.50
Post hoc analysis of calfactant use in immunocompromised children with acute lung injury: Impact and feasibility of further clinical trials. Pediatr Crit Care Med (2008) 1.49
Extracorporeal membrane oxygenation for severe refractory respiratory failure secondary to 2009 H1N1 influenza A. Respir Care (2011) 1.49
Prospective grading of graft-versus-host disease after unrelated donor marrow transplantation: a grading algorithm versus blinded expert panel review. Biol Blood Marrow Transplant (2003) 1.48
Tight Glycemic Control With Insulin Does Not Affect Skeletal Muscle Degradation During the Early Postoperative Period Following Pediatric Cardiac Surgery. Pediatr Crit Care Med (2015) 1.46