Published in N Engl J Med on January 29, 1976
Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study. Osteoporos Int (2005) 2.15
Increased bone adiposity and peroxisomal proliferator-activated receptor-gamma2 expression in type I diabetic mice. Endocrinology (2005) 1.70
Bone and glucose metabolism: a two-way street. Arch Biochem Biophys (2010) 1.18
Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men. Circulation (2009) 1.14
Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. J Cell Biol (2004) 1.12
Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus. BMC Endocr Disord (2014) 1.04
Streptozotocin, type I diabetes severity and bone. Biol Proced Online (2009) 1.04
Loss of RAGE defense: a cause of Charcot neuroarthropathy? Diabetes Care (2011) 1.02
Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress. BMC Cell Biol (2001) 1.01
Type I diabetic bone phenotype is location but not gender dependent. Histochem Cell Biol (2007) 1.00
Leptin treatment prevents type I diabetic marrow adiposity but not bone loss in mice. J Cell Physiol (2009) 0.96
Decreased bone mineral density at the distal radius, but not at the lumbar spine or the femoral neck, in Japanese type 2 diabetic patients. Osteoporos Int (2004) 0.96
Osteoporosis and type 2 diabetes mellitus: what do we know, and what we can do? Patient Prefer Adherence (2012) 0.93
Amelioration of type I diabetes-induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival. J Cell Physiol (2012) 0.91
Menopausal bone changes and incident fractures in diabetic women: a cohort study. Osteoporos Int (2010) 0.90
Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonist, JTT-501, on diabetic complications in Zucker diabetic fatty rats. Br J Pharmacol (2000) 0.88
Decreased Bone Mineral Density at the Femoral Neck and Lumbar Spine in South Indian Patients with Type 2 Diabetes. J Clin Diagn Res (2015) 0.87
Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosa. Bone (2009) 0.85
Evaluation of bone metabolism and bone mass in patients with type-2 diabetes mellitus. J Natl Med Assoc (2006) 0.85
Effects of improved glycaemic control on calcium and magnesium homeostasis in type II diabetes. J Clin Pathol (1988) 0.85
Beneficial Effect of Cissus quadrangularis Linn. on Osteopenia Associated with Streptozotocin-Induced Type 1 Diabetes Mellitus in Male Wistar Rats. Adv Pharmacol Sci (2014) 0.84
Protection against T1DM-Induced Bone Loss by Zinc Supplementation: Biomechanical, Histomorphometric, and Molecular Analyses in STZ-Induced Diabetic Rats. PLoS One (2015) 0.84
Is the expression of Transforming Growth Factor-Beta1 after fracture of long bones solely influenced by the healing process? Int Orthop (2012) 0.83
Aerobic glycolysis in osteoblasts. Curr Osteoporos Rep (2014) 0.83
CCAAT/enhancer binding protein β-deficiency enhances type 1 diabetic bone phenotype by increasing marrow adiposity and bone resorption. Am J Physiol Regul Integr Comp Physiol (2011) 0.81
Bone mineral density in Addison's disease: evidence for an effect of adrenal androgens on bone mass. Br Med J (Clin Res Ed) (1987) 0.81
Imbalance of RANK, RANKL and OPG expression during tibial fracture repair in diabetic rats. J Mol Histol (2008) 0.78
Dental implant survival in diabetic patients; review and recommendations. Natl J Maxillofac Surg (2013) 0.78
Osteoporosis in men with diabetes mellitus. J Osteoporos (2011) 0.78
Influences of obese (ob/ob) and diabetes (db/db) genotype mutations on lumber vertebral radiological and morphometric indices: skeletal deformation associated with dysregulated systemic glucometabolism. BMC Musculoskelet Disord (2006) 0.77
Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss. Cell Physiol Biochem (2011) 0.77
Type 1 diabetes and osteoporosis: A review of literature. Indian J Endocrinol Metab (2014) 0.77
Decreased response of osteoblasts obtained from aged Cohen diabetic sensitive rats to sex steroid hormones and 1,25OH2D3 in culture. Odontology (2006) 0.76
Bilateral symmetry of human carotid artery atherosclerosis: a multi-contrast weighted MR study. Int J Cardiovasc Imaging (2016) 0.76
The Effect of Lumbar Lordosis on Screw Loosening in Dynesys Dynamic Stabilization: Four-Year Follow-Up with Computed Tomography. Biomed Res Int (2015) 0.75
Type 1 diabetes patients have lower strength in femoral bone determined by quantitative computed tomography: A cross-sectional study. J Diabetes Investig (2015) 0.75
Short-term caloric restriction does not reduce bone mineral density in rats with early type 2 diabetes. Endocrinol Metab (Seoul) (2014) 0.75
A new perspective on mechanisms governing skeletal complications in type 1 diabetes. Ann N Y Acad Sci (2016) 0.75
Osteoporosis: prevention and management strategies. Can Fam Physician (1987) 0.75
Glucagon-like peptide-1(GLP-1) receptor agonists: potential to reduce fracture risk in diabetic patients? Br J Clin Pharmacol (2016) 0.75
Calcium and calcitonin responses to calcium infusion in type I diabetes mellitus. Postgrad Med J (1987) 0.75
Effect of targeted delivery of bone morphogenetic protein-2 on bone formation in type 1 diabetes. Int J Oral Maxillofac Implants (2015) 0.75
Compression fractures of the dorsal spine in hypoglycemic fits in diabetes. Br Med J (Clin Res Ed) (1985) 0.75
Insufficient renal 1-alpha hydroxylase and bone homeostasis in aged rats with insulin resistance or type 2 diabetes mellitus. J Bone Miner Metab (2008) 0.75
An update on the potential role of C-peptide in diabetes and osteoporosis. Endocrine (2017) 0.75
Skeletal growth and bone mineral acquisition in type 1 diabetic children; abnormalities of the GH/IGF-1 axis. Growth Horm IGF Res (2017) 0.75
Metabolism of vitamin D3-3H in human subjects: distribution in blood, bile, feces, and urine. J Clin Invest (1967) 3.69
Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone. Endocrinology (1994) 2.62
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells. Proc Natl Acad Sci U S A (1991) 2.44
Phenobarbital-induced alterations in vitamin D metabolism. J Clin Invest (1972) 2.33
A glucagon-secreting alpha-cell carcinoma of the pancreas. N Engl J Med (1966) 1.79
The metabolic fate of vitamin D3-3H in chronic renal failure. J Clin Invest (1968) 1.79
Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells. J Biol Chem (2001) 1.74
Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis. Proc Natl Acad Sci U S A (1987) 1.70
Caclium, phosphorus, and bone in renal disease and transplantation. Arch Intern Med (1969) 1.66
Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem (1997) 1.61
Cortical neurons require Otx1 for the refinement of exuberant axonal projections to subcortical targets. Neuron (1999) 1.60
Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum. J Neurosci (1994) 1.57
Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release. Proc Natl Acad Sci U S A (1989) 1.54
Postmenopausal osteoporosis. A heterogeneous disorder as assessed by histomorphometric analysis of Iliac crest bone from untreated patients. Am J Med (1982) 1.54
Matrix sialoprotein of developing bone. J Biol Chem (1983) 1.53
Absorption and metabolism of vitamin D3 in man. Am J Clin Nutr (1969) 1.51
Effect of chronic corticosteroid administration on diaphyseal and metaphyseal bone mass. J Clin Endocrinol Metab (1974) 1.40
Adult hypophosphatasia. Clinical, laboratory, and genetic investigation of a large kindred with review of the literature. Medicine (Baltimore) (1979) 1.35
In vitro assay for a humoral substance present during volume expansion and uraemia. Nature (1968) 1.30
Systemic mastocytosis. Arch Intern Med (1984) 1.30
Effects of prolonged thyrocalcitonin administration on Paget's disease of bone. N Engl J Med (1970) 1.27
Effect of experimental chronic renal insufficiency on bone mineral and collagen maturation. J Clin Invest (1972) 1.25
Subclinical vitamin D deficiency in postmenopausal women with low vertebral bone mass. J Clin Endocrinol Metab (1991) 1.25
Transcriptional regulation of repressor synthesis in mycobacteriophage L5. Mol Microbiol (1995) 1.24
Bone turnover in postmenopausal osteoporosis. Effect of calcitonin treatment. J Clin Invest (1988) 1.22
Tuberculous pericarditis. Arch Intern Med (1979) 1.22
Osteopetrosis, renal tubular acidosis and basal ganglia calcification in three sisters. Am J Med (1980) 1.22
Heparin-induced osteopenia: an appraisal. Adv Exp Med Biol (1975) 1.18
Bone mineralization and osteoblast differentiation are negatively modulated by integrin alpha(v)beta3. J Bone Miner Res (2001) 1.16
Pseudofractures in the absence of osteomalacia. Skeletal Radiol (1982) 1.12
Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model. Calcif Tissue Int (1998) 1.12
Estrogen status and heredity are major determinants of premenopausal bone mass. J Clin Invest (1992) 1.08
In vitro and in vivo induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene. Calcif Tissue Int (2001) 1.07
Effects of prednisone on vitamin D metabolism in man. J Clin Endocrinol Metab (1968) 1.07
The influence of age on the intestinal absorption of 47-Ca absorption in post-menopausal osteoporosis. J Clin Invest (1965) 1.07
Increased monocyte interleukin-1 activity and decreased vertebral bone density in patients with fasting idiopathic hypercalciuria. J Clin Endocrinol Metab (1990) 1.05
Effects of hypervitaminosis A on the bone and mineral metabolism of the rat. Endocrinology (1988) 1.04
Metabolism of vitamin D3-3H in vitamin D-resistant rickets and familial hypophosphatemia. J Clin Invest (1967) 1.03
Effects of one-year treatment with estrogens on bone mass, intestinal calcium absorption, and 25-hydroxyvitamin D-1 alpha-hydroxylase reserve in postmenopausal osteoporosis. Calcif Tissue Int (1988) 1.03
Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells. J Cell Biochem (2000) 1.03
Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling. J Biol Chem (2000) 1.02
Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: differentiation is associated with repression of metalloproteinase biosynthesis. Endocrinology (1994) 1.02
Plasma calcium and phosphate levels in an adult noninsulin-dependent diabetic population. Calcif Tissue Int (1986) 1.01
Dietary L-lysine and calcium metabolism in humans. Nutrition (1993) 1.00
Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans. Calcif Tissue Int (1984) 1.00
Placental calcium binding protein in rats. Apparent identity with vitamin D-dependent calcium binding protein from rat intestine. J Biol Chem (1978) 0.99
Editorial: Vitamin D, the kidney and calcium homeostasis. Kidney Int (1972) 0.99
Abnormal regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase activity by calcium and calcitonin in renal cortex from hypophosphatemic (Hyp) mice. Endocrinology (1984) 0.99
The bone "quality" problem. Calcif Tissue Int (1992) 0.98
Coherence therapy does not prevent axial bone loss in osteoporotic women: a preliminary comparative study. J Clin Endocrinol Metab (1988) 0.98
Intestinal calcium absorption: nature of defect in chronic renal disease. Science (1969) 0.97
Placental transfer of vitamin D3 and 25-hydroxycholecalciferol in the rat. J Lab Clin Med (1971) 0.97
Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells. J Clin Invest (1991) 0.97
Osteitis pubis in an athlete. Calcif Tissue Int (1986) 0.96
Production of interleukin-6 in human osteoblasts and human bone marrow stromal cells: evidence that induction by interleukin-1 and tumor necrosis factor-alpha is not regulated by ovarian steroids. Endocrinology (1995) 0.96
Intestinal absorption of calcium. Arch Intern Med (1972) 0.96
The effect of streptozotocin-induced chronic diabetes mellitus on bone and mineral homeostasis in the rat. J Lab Clin Med (1981) 0.95
Rhabdomyolysis associated with hyperosmolar nonketotic coma. Diabetes Care (1985) 0.95
An intact N terminus is required for the anabolic action of parathyroid hormone on adult female rats. J Bone Miner Res (1997) 0.95
Glucagon-induced hypocalcemia in man. J Clin Endocrinol Metab (1969) 0.95
Clinical utility of bone mass measurements in adults: consensus of an international panel. The Society for Clinical Densitometry. Semin Arthritis Rheum (1996) 0.95
Intestinal calcium transport: the role of sodium. Science (1972) 0.95
Altered osteoblast gluconeogenesis in X-linked hypophosphatemic mice is associated with a depressed intracellular pH. Calcif Tissue Int (1995) 0.95
Control of vitamin D-dependent calcium-binding protein in rat intestine by growth and fasting. J Biol Chem (1977) 0.95
Osteoporotic bone fragility. Detection by ultrasound transmission velocity. JAMA (1989) 0.95
Regulation of 25 hydroxyvitamin D3 1-hydroxylase in serum-free monolayer culture of mouse kidney. Endocrinology (1982) 0.94
The parathyroid adenoma. JAMA (1968) 0.94
Endocrine syndromes associated with pancreatic islet cell tumors. Med Clin North Am (1968) 0.93
Correction of abnormal bone and mineral metabolism in chronic streptozotocin-induced diabetes mellitus in the rat by insulin therapy. Endocrinology (1981) 0.93
Effect of alcohol ingestion on bone and mineral metabolism in rats. Am J Physiol (1980) 0.93
Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells. Am J Physiol (1987) 0.93
Extracellular-signal regulated kinase signaling pathway mediates downregulation of type I procollagen gene expression by FGF-2, PDGF-BB, and okadaic acid in osteoblastic cells. J Cell Biochem (2000) 0.92
A novel T cell cytokine stimulates interleukin-6 in human osteoblastic cells. J Bone Miner Res (1999) 0.92
Waldenström's macroglobulinemia. Arch Intern Med (1983) 0.92
Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male. Calcif Tissue Res (1978) 0.92
Calusterone in the therapy for advanced breast cancer. JAMA (1972) 0.92
Single and dual energy tomographic analysis of spinal trabecular bone: a comparative study in normal and osteoporotic women. J Clin Endocrinol Metab (1987) 0.92
Role of the thyroid gland during glucagon-induced hypocalcemia in the dog. Am J Physiol (1969) 0.92
Effects of a new positioner on the precision of hip bone mineral density measurements. J Bone Miner Res (1997) 0.91
Role of magnesium metabolism and the effects of fluoride therapy in Paget's disease of bone. J Clin Endocrinol Metab (1968) 0.91
Regulation of interleukin-8 gene expression by interleukin-1beta, osteotropic hormones, and protein kinase inhibitors in normal human bone marrow stromal cells. J Biol Chem (1996) 0.91
Effect of magnesium depletion on responsiveness to parathyroid hormone in parathyroidectomized rats. J Clin Invest (1972) 0.91
25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol: conversion impaired by systemic metabolic acidosis. Science (1977) 0.91
Systemic mastocytosis presenting as osteoporosis: a clinical and histomorphometric study. J Clin Endocrinol Metab (1991) 0.90
Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology (1992) 0.90
Diabetes and peripheral neuropathy. Diabetes Care (1998) 0.90
Abnormal bone mineral maturation in the chronic uremic state. J Clin Invest (1973) 0.90
Impaired insulin action in rats with non-insulin-dependent diabetes. Diabetes (1984) 0.90
On death and dying. JAMA (1972) 0.90
Nondialyzable urinary hydroxyproline as an index of bone collagen formation. J Clin Endocrinol Metab (1970) 0.89
Sp1/Sp3 and PU.1 differentially regulate beta(5) integrin gene expression in macrophages and osteoblasts. J Biol Chem (2000) 0.89
Thallium stress tests and bank vaults. N Engl J Med (1988) 0.89
Activation of extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2) by FGF-2 and PDGF-BB in normal human osteoblastic and bone marrow stromal cells: differences in mobility and in-gel renaturation of ERK1 in human, rat, and mouse osteoblastic cells. Biochem Biophys Res Commun (1997) 0.89
Skeletal casein kinase activity defect in the HYP mouse. Calcif Tissue Int (1997) 0.89
Dual energy radiography versus quantitative computer tomography for the diagnosis of osteoporosis. J Clin Endocrinol Metab (1990) 0.88
Dual energy radiography (DER): a preliminary comparative study. Calcif Tissue Int (1988) 0.88
Dexamethasone regulates IL-1 beta and TNF-alpha-induced interleukin-8 production in human bone marrow stromal and osteoblast-like cells. Calcif Tissue Int (1994) 0.88