Published in Eur J Neurosci on November 01, 2002
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Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation. Biochem J (2004) 1.42
Protein kinase C mediates up-regulation of tetrodotoxin-resistant, persistent Na+ current in rat and mouse sensory neurones. J Physiol (2005) 1.34
Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2. Pain (2008) 1.20
Nucleotide signaling and cutaneous mechanisms of pain transduction. Brain Res Rev (2008) 1.19
Nucleotide signaling in nervous system development. Pflugers Arch (2006) 1.18
Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior. Mol Pain (2010) 1.15
P2Y receptors and pain transmission. Purinergic Signal (2004) 1.12
P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation. Proc Natl Acad Sci U S A (2005) 1.12
Crossing the pain barrier: P2 receptors as targets for novel analgesics. J Physiol (2003) 1.03
Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats. Mol Pain (2008) 0.97
Peripheral sensitisation of nociceptors via G-protein-dependent potentiation of mechanotransduction currents. J Physiol (2009) 0.97
The P2Y2 receptor sensitizes mouse bladder sensory neurons and facilitates purinergic currents. J Neurosci (2010) 0.92
Distribution of ecto-nucleotidases in mouse sensory circuits suggests roles for nucleoside triphosphate diphosphohydrolase-3 in nociception and mechanoreception. Neuroscience (2011) 0.89
The ADP receptor P2Y1 is necessary for normal thermal sensitivity in cutaneous polymodal nociceptors. Mol Pain (2011) 0.88
Functions of neuronal P2Y receptors. Pflugers Arch (2006) 0.88
Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade. Pain (2011) 0.85
ATP receptors in pain sensation: Involvement of spinal microglia and P2X(4) receptors. Purinergic Signal (2005) 0.85
Neuroprotective roles of the P2Y(2) receptor. Purinergic Signal (2012) 0.84
Modeling and analysis of the molecular basis of pain in sensory neurons. PLoS One (2009) 0.84
P2 receptors and chronic pain. Purinergic Signal (2007) 0.83
Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain (2014) 0.82
Purines as potential morphogens during embryonic development. Purinergic Signal (2012) 0.82
P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors. J Neurosci (2016) 0.80
P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway. PLoS One (2015) 0.77
Purinergic P2Y2 Receptor Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: NEW AP-1 TRANSCRIPTION FACTOR SITE AND NEGATIVE REGULATOR. J Biol Chem (2015) 0.76
Enhancement of acid-sensing ion channel activity by metabotropic P2Y UTP receptors in primary sensory neurons. Purinergic Signal (2015) 0.75
Uridine from Pleurotus giganteus and Its Neurite Outgrowth Stimulatory Effects with Underlying Mechanism. PLoS One (2015) 0.75
Cortical Spreading Depression Closes Paravascular Space and Impairs Glymphatic Flow: Implications for Migraine Headache. J Neurosci (2017) 0.75
Deletion of the murine ATP/UTP receptor P2Y2 alters mechanical and thermal response properties in polymodal cutaneous afferents. Neuroscience (2016) 0.75
Protons open acid-sensing ion channels by catalyzing relief of Ca2+ blockade. Neuron (2003) 2.24
Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia. Circ Res (2006) 2.20
Circulation and chemotaxis of fetal hematopoietic stem cells. PLoS Biol (2004) 2.18
ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons. Mol Pain (2005) 1.95
Permeation and selectivity in calcium channels. Annu Rev Physiol (2002) 1.88
The effect of exercise on neuropathic symptoms, nerve function, and cutaneous innervation in people with diabetic peripheral neuropathy. J Diabetes Complications (2012) 1.79
Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels. Neuron (2010) 1.53
Restorative effects of neurotrophin treatment on diabetes-induced cutaneous axon loss in mice. Exp Neurol (2003) 1.50
A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3. J Gen Physiol (2007) 1.38
Botulinum toxin type A inhibits sensory neuropeptide release in rat bladder models of acute injury and chronic inflammation. BJU Int (2008) 1.25
Early loss of peptidergic intraepidermal nerve fibers in an STZ-induced mouse model of insensate diabetic neuropathy. Pain (2008) 1.15
Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2. Br J Pharmacol (2010) 1.15
Pro-NGF, sortilin, and p75NTR: potential mediators of injury-induced apoptosis in the mouse dorsal root ganglion. Brain Res (2007) 1.13
Botulinum toxin type a inhibits calcitonin gene-related peptide release from isolated rat bladder. J Urol (2006) 1.07
Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice. Diabetes (2008) 1.07
Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate. Nat Neurosci (2004) 1.07
Vitamin D deficiency promotes skeletal muscle hypersensitivity and sensory hyperinnervation. J Neurosci (2011) 1.05
Beneficial actions of neurotrophin treatment on diabetes-induced hypoalgesia in mice. J Pain (2003) 1.02
Exercise increases insulin content and basal secretion in pancreatic islets in type 1 diabetic mice. Exp Diabetes Res (2011) 1.00
Prenatal exposure to elevated NT3 disrupts synaptic selectivity in the spinal cord. J Neurosci (2007) 0.99
Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy. Diabetes (2009) 0.98
Contrasting phenotypes of putative proprioceptive and nociceptive trigeminal neurons innervating jaw muscle in rat. Mol Pain (2005) 0.98
Comparison of ketamine versus combination of ketamine and medetomidine in injectable anesthetic protocols: chemical immobilization in macaques and tissue reaction in rats. Contemp Top Lab Anim Sci (2003) 0.97
Use-dependent inhibition of P2X3 receptors by nanomolar agonist. J Neurosci (2005) 0.96
Neurotrophin-3 reverses chronic mechanical hyperalgesia induced by intramuscular acid injection. J Neurosci (2004) 0.95
Acidic saline-induced primary and secondary mechanical hyperalgesia in mice. J Pain (2009) 0.91
Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3). Bioorg Med Chem Lett (2009) 0.91
Quantitative single-cell differences in mu-opioid receptor mRNA distinguish myelinated and unmyelinated nociceptors. J Neurosci (2003) 0.91
Aerobic exercise alters analgesia and neurotrophin-3 synthesis in an animal model of chronic widespread pain. Phys Ther (2010) 0.90
Peripheral nervous system insulin resistance in ob/ob mice. Acta Neuropathol Commun (2013) 0.90
A role for the P2X receptor in urinary tract physiology and in the pathophysiology of urinary dysfunction. Eur Urol (2005) 0.87
The return of bedside rounds. J Gen Intern Med (2011) 0.87
Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy. J Neurophysiol (2011) 0.86
A novel mouse skeletal muscle-nerve preparation and in vitro model of ischemia. J Neurosci Methods (2006) 0.86
Exercise-mediated improvements in painful neuropathy associated with prediabetes in mice. Pain (2013) 0.86
Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3). Bioorg Med Chem Lett (2009) 0.85
Diabetes-induced chemogenic hypoalgesia is paralleled by attenuated stimulus-induced fos expression in the spinal cord of diabetic mice. J Pain (2007) 0.84
In vivo peripheral nervous system insulin signaling. J Peripher Nerv Syst (2013) 0.83
Case records of the Massachusetts General Hospital. Case 36-2013. A 38-year-old woman with anemia and thrombocytopenia. N Engl J Med (2013) 0.81
Nerve growth factor blocks the glucose-induced down-regulation of caveolin-1 expression in Schwann cells via p75 neurotrophin receptor signaling. J Biol Chem (2003) 0.80
Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury. Exp Neurol (2005) 0.80
Splicing it up: a variant of the N-type calcium channel specific for pain. Neuron (2004) 0.78
Neurobiology: new player in pain. Nature (2003) 0.77
Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3). Bioorg Med Chem Lett (2011) 0.77
High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors. Bioorg Med Chem Lett (2010) 0.76
Neuroscience: a local route to pain relief. Nature (2007) 0.76
Streptozotocin-induced diabetes partially attenuates the effects of a high-fat diet on liver and brain fatty acid composition in mice. Lipids (2013) 0.75
Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567. ACS Chem Neurosci (2009) 0.75
Supporting Medical Students' Pursuit of Longitudinal Patient Experiences: Piloting an Innovative Visit Notification Tool at the Massachusetts General Hospital. Acad Med (2016) 0.75
The Effects Of A High-fat Diet And Exercise On The Pgc-1α-fndc5/irisin Pathway In C57bl/6 Mice: 1968 Board #120 June 2, 3: 30 PM - 5: 00 PM. Med Sci Sports Exerc (2016) 0.75