Published in Gene on October 16, 2002
Biological determinants of endocrine resistance in breast cancer. Nat Rev Cancer (2009) 5.89
A comprehensive pathway map of epidermal growth factor receptor signaling. Mol Syst Biol (2005) 5.68
Molecular aspects of thyroid hormone actions. Endocr Rev (2010) 3.29
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer (2007) 3.28
L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood (2006) 3.17
Nuclear cyclin D1: an oncogenic driver in human cancer. J Cell Physiol (2009) 2.50
AR, the cell cycle, and prostate cancer. Nucl Recept Signal (2008) 2.44
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature (2010) 2.20
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol Cell Biol (2006) 1.65
Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells. Cancer Res (2010) 1.55
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation. Proc Natl Acad Sci U S A (2006) 1.52
Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad. J Biol Chem (2004) 1.48
Forced G1-phase reduction alters mode of division, neuron number, and laminar phenotype in the cerebral cortex. Proc Natl Acad Sci U S A (2009) 1.47
Spliced-leader RNA trans splicing in a chordate, Oikopleura dioica, with a compact genome. Mol Cell Biol (2004) 1.33
Systems analysis of shoot apical meristem growth and development: integrating hormonal and mechanical signaling. Plant Cell (2012) 1.31
The carboxyl-terminal domain of RNA polymerase II is phosphorylated by a complex containing cdk9 and infected-cell protein 22 of herpes simplex virus 1. J Virol (2005) 1.30
A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells. J Biol Chem (2008) 1.22
Genetic replacement of cyclin D1 function in mouse development by cyclin D2. Mol Cell Biol (2005) 1.15
The cyclin D1b splice variant: an old oncogene learns new tricks. Cell Div (2006) 1.15
Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells. J Biol Chem (2009) 1.14
Cyclin D1, Id1 and EMT in breast cancer. BMC Cancer (2011) 1.13
Genome-wide analysis of the diatom cell cycle unveils a novel type of cyclins involved in environmental signaling. Genome Biol (2010) 1.12
INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases. Biochem J (2006) 1.12
Impact of differential cyclin D1 expression and localisation in prostate cancer. Br J Cancer (2007) 1.09
Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity. Cold Spring Harb Perspect Biol (2009) 1.09
Zona occludens-2 inhibits cyclin D1 expression and cell proliferation and exhibits changes in localization along the cell cycle. Mol Biol Cell (2008) 1.09
Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1. Endocrinology (2009) 1.07
The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines. Mol Cancer (2006) 1.07
Transcriptional regulation by a DNA-associated form of cyclin D1. Mol Biol Cell (2005) 1.06
Phosphorylation of Mcm2 by Cdc7 promotes pre-replication complex assembly during cell-cycle re-entry. Mol Cell (2009) 1.06
Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study. Biol Sex Differ (2011) 1.04
Distinct proliferative and transcriptional effects of the D-type cyclins in vivo. Cell Cycle (2008) 1.03
Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. Mol Biol Cell (2007) 1.02
Down-regulation of the oncogene cyclin D1 increases migratory capacity in breast cancer and is linked to unfavorable prognostic features. Am J Pathol (2010) 1.02
Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells. J Cell Biol (2004) 1.02
The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes. J Clin Invest (2004) 1.00
Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors. Cell Cycle (2015) 0.98
CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186. Oncotarget (2015) 0.97
Kaposi's sarcoma-associated herpesvirus K-cyclin interacts with Cdk9 and stimulates Cdk9-mediated phosphorylation of p53 tumor suppressor. J Virol (2007) 0.97
Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo. Cell Cycle (2009) 0.97
The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans. BMC Dev Biol (2007) 0.97
Nutrition controls mitochondrial biogenesis in the Drosophila adipose tissue through Delg and cyclin D/Cdk4. PLoS One (2009) 0.96
Induction of G1 cell cycle arrest and cyclin D1 down-regulation in response to pericarp extract of Baneh in human breast cancer T47D cells. Daru (2012) 0.96
Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin. J Virol (2006) 0.96
Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription. J Endocrinol (2008) 0.95
Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer. Oncogene (2008) 0.94
Early growth response (EGR)-1 is required for timely cell-cycle entry and progression in hepatocytes after acute carbon tetrachloride exposure in mice. Am J Physiol Gastrointest Liver Physiol (2011) 0.93
Cyclin D does not provide essential Cdk4-independent functions in Drosophila. Genetics (2004) 0.92
Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function. J Biol Chem (2011) 0.92
Molecular pathway reconstruction and analysis of disturbed gene expression in depressed individuals who died by suicide. PLoS One (2012) 0.91
Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells. J Hematol Oncol (2010) 0.91
Cells lacking IKKα show nuclear cyclin D1 overexpression and a neoplastic phenotype: role of IKKα as a tumor suppressor. Mol Cancer Res (2011) 0.88
Cyclin D1 promotes neurogenesis in the developing spinal cord in a cell cycle-independent manner. Proc Natl Acad Sci U S A (2011) 0.88
The proliferating cell nuclear antigen regulates retinoic acid receptor transcriptional activity through direct protein-protein interaction. Nucleic Acids Res (2005) 0.88
Developmental stability: a major role for cyclin G in drosophila melanogaster. PLoS Genet (2011) 0.87
Patterns of p57Kip2 expression in embryonic rat brain suggest roles in progenitor cell cycle exit and neuronal differentiation. Dev Neurobiol (2009) 0.87
Cyclin D1 regulates hepatic estrogen and androgen metabolism. Am J Physiol Gastrointest Liver Physiol (2010) 0.87
A gender-specific retinoblastoma-related protein in Volvox carteri implies a role for the retinoblastoma protein family in sexual development. Plant Cell (2008) 0.87
Trichinella spiralis: nurse cell formation with emphasis on analogy to muscle cell repair. Parasit Vectors (2008) 0.86
Cyclin D2 is a GATA4 cofactor in cardiogenesis. Proc Natl Acad Sci U S A (2014) 0.86
Crystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9. J Mol Biol (2006) 0.86
An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas. J Neurooncol (2008) 0.85
Alteration of cyclin D1 in gastric carcinoma and its clinicopathologic significance. World J Gastroenterol (2004) 0.85
The Wnt pathway destabilizes adherens junctions and promotes cell migration via β-catenin and its target gene cyclin D1. FEBS Open Bio (2012) 0.84
Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Mol Endocrinol (2014) 0.84
Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer. Virchows Arch (2008) 0.84
Optimization of immunolocalization of cell cycle proteins in human corneal endothelial cells. Mol Vis (2011) 0.84
Herpes simplex virus 1 ICP22 inhibits the transcription of viral gene promoters by binding to and blocking the recruitment of P-TEFb. PLoS One (2012) 0.84
Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival. Mol Biol Cell (2008) 0.83
Contribution of personalized Cyclin D1 genotype to triple negative breast cancer risk. Biomedicine (Taipei) (2014) 0.83
Signal transduction involving the dmp1 transcription factor and its alteration in human cancer. Clin Med Oncol (2008) 0.82
Carcinoma of tongue and the buccal mucosa represent different biological subentities of the oral carcinoma. J Cancer Res Clin Oncol (2006) 0.81
Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and Apoptosis. Evid Based Complement Alternat Med (2013) 0.81
ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma. Toxicol Sci (2011) 0.81
Age-specific functional epigenetic changes in p21 and p16 in injury-activated satellite cells. Stem Cells (2015) 0.81
Retinoblastoma protein modulates the inverse relationship between cellular proliferation and elastogenesis. J Biol Chem (2011) 0.80
Cyclin D3 critically regulates the balance between self-renewal and differentiation in skeletal muscle stem cells. Stem Cells (2013) 0.80
E2F promoter-regulated oncolytic adenovirus with p16 gene induces cell apoptosis and exerts antitumor effect on gastric cancer. Dig Dis Sci (2008) 0.79
Enhanced skin carcinogenesis and lack of thymus hyperplasia in transgenic mice expressing human cyclin D1b (CCND1b). Mol Carcinog (2009) 0.79
MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation. Blood Cancer J (2013) 0.79
The elements of human cyclin D1 promoter and regulation involved. Clin Epigenetics (2011) 0.79
Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs. Front Genet (2013) 0.79
Identifying gastric cancer related genes using the shortest path algorithm and protein-protein interaction network. Biomed Res Int (2014) 0.79
A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathway. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.79
Cyclin D3 promotes pancreatic β-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes. Proc Natl Acad Sci U S A (2014) 0.78
Prolactin promotes mammary pathogenesis independently from cyclin D1. Am J Pathol (2012) 0.78
A single cyclin-CDK complex is sufficient for both mitotic and meiotic progression in fission yeast. Nat Commun (2015) 0.78
TRPC6 regulates cell cycle progression by modulating membrane potential in bone marrow stromal cells. Br J Pharmacol (2014) 0.77
T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes. Mol Syst Biol (2015) 0.77
Cyclin D1b overexpression inhibits cell proliferation and induces cell apoptosis in cervical cancer cells in vitro and in vivo. Int J Clin Exp Pathol (2014) 0.77
Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway. BMC Cancer (2015) 0.76
Multifaceted interactions and regulation between antizyme and its interacting proteins cyclin D1, ornithine decarboxylase and antizyme inhibitor. Oncotarget (2015) 0.76
Cyclin D1, cancer progression, and opportunities in cancer treatment. J Mol Med (Berl) (2016) 0.76
Overexpression of Cell Cycle Proteins of Peripheral Lymphocytes in Patients with Alzheimer's Disease. Psychiatry Investig (2015) 0.76
Cyclin D1 in the Liver: Role of Noncanonical Signaling in Liver Steatosis and Hormone Regulation. Ochsner J (2017) 0.75
Magnolol pretreatment attenuates heat stress-induced IEC-6 cell injury. J Zhejiang Univ Sci B (2016) 0.75
MAJOR MOLECULAR GENETIC DRIVERS IN SPORADIC PRIMARY HYPERPARATHYROIDISM. Trans Am Clin Climatol Assoc (2016) 0.75
The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells. Biol Direct (2016) 0.75
Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α. Sci Rep (2016) 0.75
New targets for viral cyclins. Cell Cycle (2003) 0.78