Published in J Biol Inorg Chem on September 25, 2002
Towards Antitumor Active trans-Platinum Compounds. Eur J Inorg Chem (2009) 1.08
Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1. J Biol Inorg Chem (2009) 0.92
A bulky platinum triamine complex that reacts faster with guanosine 5'-monophosphate than with N-acetylmethionine. J Inorg Biochem (2009) 0.84
Palladium(II) and platinum(II) bind strongly to an engineered blue copper protein. Inorg Chem (2011) 0.82
Targeting retroviral Zn finger-DNA interactions: a small-molecule approach using the electrophilic nature of trans-platinum-nucleobase compounds. Chem Biol (2006) 1.47
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. J Biol Chem (2002) 1.28
Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure. J Am Chem Soc (2004) 1.26
Turning gene function ON and OFF using sense and antisense photo-morpholinos in zebrafish. Development (2012) 1.19
Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjug Chem (2003) 1.13
Pt(IV) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate. Chem Commun (Camb) (2011) 1.07
A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464. J Biol Inorg Chem (2002) 1.04
Methionine sulfoxides on PrPSc: a prion-specific covalent signature. Biochemistry (2008) 1.03
Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [(trans-PtCl(NH(3))(2))(2)(mu-trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2))](4+) (BBR3464). Inorg Chem (2002) 1.01
Is glutathione the major cellular target of cisplatin? A study of the interactions of cisplatin with cancer cell extracts. J Med Chem (2009) 1.01
Biological consequences of trinuclear platinum complexes: comparison of [[trans-PtCl(NH3)2]2mu-(trans-Pt(NH3)2(H2N(CH2)6-NH2)2)]4+ (BBR 3464) with its noncovalent congeners. Mol Pharmacol (2005) 1.00
What do we know about the reduction of Pt(IV) pro-drugs? J Inorg Biochem (2012) 1.00
DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines. Biochemistry (2003) 1.00
Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization. J Med Chem (2002) 0.97
DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts. Biochemistry (2003) 0.97
Reaction of polynuclear platinum antitumor compounds with reduced glutathione studied by multinuclear (1H, 1H-15N gradient heteronuclear single-quantum coherence, and 195Pt) NMR spectroscopy. Inorg Chem (2003) 0.96
Nuclear localization signal-targeted poly(ethylene glycol) conjugates as potential carriers and nuclear localizing agents for carboplatin analogues. Bioconjug Chem (2004) 0.95
Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents. Biochemistry (2004) 0.95
Facile preparation of mono-, di- and mixed-carboxylato platinum(IV) complexes for versatile anticancer prodrug design. Chemistry (2012) 0.95
New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs. Chem Commun (Camb) (2010) 0.92
Effects of geometric isomerism in dinuclear platinum antitumor complexes on aquation reactions in the presence of perchlorate, acetate and phosphate. J Biol Inorg Chem (2005) 0.92
Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)]. Nucleic Acids Res (2005) 0.90
Unique cooperative binding interaction observed between a minor groove binding Pt antitumor agent and Hoechst dye 33258. Inorg Chem (2005) 0.89
Effects of geometric isomerism in dinuclear antitumor platinum complexes on their interactions with N-acetyl-L-methionine. J Biol Inorg Chem (2005) 0.88
Differences in the cellular response and signaling pathways of cisplatin and BBR3464 ([[trans-PtCl(NH3)(2)]2mu-(trans-Pt(NH3)(2)(H2N(CH2)(6)-NH2)2)]4+) influenced by copper homeostasis. Biochem Pharmacol (2006) 0.88
trans-Platinum planar amine compounds with [N2O2] ligand donor sets: effects of carboxylate leaving groups and steric hindrance on chemical and biological properties. Inorg Chem (2006) 0.87
Synthesis and antitumor activity of quinonoid derivatives of cannabinoids. J Med Chem (2004) 0.87
Enhancement of aqueous solubility and stability employing a trans acetate axis in trans planar amine platinum compounds while maintaining the biological profile. J Med Chem (2005) 0.87
Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes. J Inorg Biochem (2004) 0.85
Differences in breast cancer diagnosis and treatment: experiences of insured and uninsured women in a safety-net setting. Inquiry (2008) 0.85
Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes. Chemistry (2008) 0.85
Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines. J Med Chem (2002) 0.84
Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes. FEBS J (2006) 0.84
Synthesis and DNA conformational changes of non-covalent polynuclear platinum complexes. J Inorg Biochem (2004) 0.84
Platinum(IV) prodrugs with haloacetato ligands in the axial positions can undergo hydrolysis under biologically relevant conditions. Angew Chem Int Ed Engl (2013) 0.84
Circular dichroism study of the irreversibility of conformational changes induced by polyamine-linked dinuclear platinum compounds. J Inorg Biochem (2002) 0.83
Novel transplatinum(II) complexes with [N2O2] donor sets. Cellular pharmacology and apoptosis induction in Pam 212-ras cells. J Med Chem (2006) 0.83
Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action. J Biol Chem (2003) 0.82
A surprisingly stable macrochelate formed from the reaction of cis dinuclear platinum antitumor compounds with reduced glutathione. Inorg Chem (2005) 0.82
Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding. J Inorg Biochem (2004) 0.82
Platination of nucleobases to enhance noncovalent recognition in protein-DNA/RNA complexes. Inorg Chem (2005) 0.82
Trans labilization of am(m)ine ligands from platinum(II) complexes by cancer cell extracts. J Biol Inorg Chem (2008) 0.82
Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand. J Biol Inorg Chem (2005) 0.81
Nonclassic metallointercalators with dipyridophenazine: DNA interaction studies and leishmanicidal activity. Inorg Chem (2013) 0.81
c-Abl phosphorylates E6AP and regulates its E3 ubiquitin ligase activity. Biochemistry (2013) 0.80
Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies. J Med Chem (2006) 0.80
Reduction of cis,trans,cis-[PtCl2(OCOCH3)2(NH3)2] by aqueous extracts of cancer cells. J Med Chem (2007) 0.80
1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin. Arch Biochem Biophys (2006) 0.80
Pyridine-carboxylate complexes of platinum. Effect of N,O-chelate formation on model bifunctional DNA-DNA and DNA-protein interactions. Inorg Chem (2005) 0.80
Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis. J Biol Inorg Chem (2008) 0.80
Mechanism of the membrane interaction of polynuclear platinum anticancer agents. Implications for cellular uptake. Biochemistry (2006) 0.79
Interactions of cisplatin and transplatin with proteins. Comparison of binding kinetics, binding sites and reactivity of the Pt-protein adducts of cisplatin and transplatin towards biological nucleophiles. J Inorg Biochem (2002) 0.79
Preparation, Structure and Stability of cis-{Cr(phen)(2)[OP(O)(OC(6)H(5))(2)](H(2)O)}(2+) as a Model for Cr(III)-DNA Adducts. Inorg Chem (1998) 0.79
Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand. J Inorg Biochem (2013) 0.78
Pharmacokinetics and metabolism of a new potent antiepileptic drug, 2,2,3,3-tetramethycyclopropanecarbonylurea, in rats. Drug Metab Dispos (2005) 0.78
Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles. J Med Chem (2006) 0.78
Modulation of Nucleotide Binding of trans Platinum(II) Complexes by Planar Ligands. A Combined Proton NMR and Molecular Mechanics Study. Inorg Chem (1997) 0.78
The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug. Chem Commun (Camb) (2003) 0.78
Studies on cellular accumulation of satraplatin and its major metabolite JM118 and their interactions with glutathione. Mol Pharm (2010) 0.78
DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)]. Biochem Pharmacol (2007) 0.78
On the stability of Pt(IV) pro-drugs with haloacetato ligands in the axial positions. Chemistry (2014) 0.77
Computed tomography angiography: improving diagnostic yield and cost effectiveness in the initial evaluation of spontaneous nonsubarachnoid intracerebral hemorrhage. J Neurosurg (2012) 0.77
Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues. Chem Res Toxicol (2003) 0.76
Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin. Nucleic Acids Res (2004) 0.76
Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro. Chem Res Toxicol (2010) 0.76
Thiolate-bridged heterodinuclear platinum-zinc chelates as models for ternary platinum-DNA-protein complexes and zinc ejection from zinc fingers. Evidence from studies using ESI-mass spectrometry. Chem Commun (Camb) (2005) 0.76
Structure and unique interactions with DNA of a cationic trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand. Angew Chem Int Ed Engl (2005) 0.76
Greater binding affinity of trivalent antimony to a CCCH zinc finger domain compared to a CCHC domain of kinetoplastid proteins. Metallomics (2012) 0.76
Studying protein-peptide interactions using benzophenone units: a case study of protein kinase B/Akt and its inhibitor PTR6154. Anal Biochem (2011) 0.76
Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine. J Inorg Biochem (2007) 0.75
Zygote serine decreased uptake from the fertilization medium is associated with implantation and pregnancy. J Assist Reprod Genet (2014) 0.75
Low-loss, robust fusion splicing of silica to chalcogenide fiber for integrated mid-infrared laser technology development. Opt Lett (2015) 0.75
Mass spectrometric studies of the formation and reactivity of trans-[PtCl2(Am)(piperidinopiperidine)] x HCl complexes with ubiquitin. Rapid Commun Mass Spectrom (2005) 0.75
Preface for the JIB Special Issue on Latin American Bioinorganic Chemistry. J Inorg Biochem (2014) 0.75
Preparation, cytotoxicity and interactions with nucleophiles of three isomeric transplatinum complexes containing methylpiperidine ligands. J Inorg Biochem (2005) 0.75
The induction of lysis in lysogenic strains of Escherichia coli by a new antitumor transplatin derivative and its DNA interactions. Dalton Trans (2015) 0.75
Tuning the reactivity of Sp1 zinc fingers with platinum complexes. Dalton Trans (2016) 0.75