Published in J Am Chem Soc on February 25, 2004
Formation and repair of interstrand cross-links in DNA. Chem Rev (2006) 2.91
Excursions in polynuclear platinum DNA binding. Chem Commun (Camb) (2010) 1.22
Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma. Neuro Oncol (2006) 1.13
Rates of intercalator-driven platination of DNA determined by a restriction enzyme cleavage inhibition assay. J Biol Inorg Chem (2010) 1.01
The phosphate clamp: a small and independent motif for nucleic acid backbone recognition. Nucleic Acids Res (2010) 0.96
Unusual DNA binding modes for metal anticancer complexes. Biochimie (2009) 0.95
Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer. Chemistry (2009) 0.92
Effects of geometric isomerism in dinuclear platinum antitumor complexes on aquation reactions in the presence of perchlorate, acetate and phosphate. J Biol Inorg Chem (2005) 0.92
Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design. Dalton Trans (2007) 0.90
Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes. Chemistry (2008) 0.85
Determination of the kinetic profile of a dinuclear platinum anticancer complex in the presence of sulfate: introducing a new tool for the expedited analysis of 2D [(1)H,( 15)N] HSQC NMR spectra. Inorg Chem (2010) 0.85
Mass spectrometry evidence for cisplatin as a protein cross-linking reagent. Anal Chem (2011) 0.85
Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA. Nucleic Acids Res (2010) 0.82
Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex. J Biol Inorg Chem (2009) 0.79
Differences in conformational dynamics of [Pt3(HPTAB)]6+-DNA adducts with various cross-linking modes. Nucleic Acids Res (2009) 0.78
Competitive formation of both long-range 5'-5' and short-range antiparallel 3'-3' DNA interstrand cross-links by a trinuclear platinum complex on binding to a 10-mer duplex. Dalton Trans (2012) 0.78
Solution studies on DNA interactions of substitution-inert platinum complexes mediated via the phosphate clamp. Dalton Trans (2015) 0.78
Solution studies of dinuclear polyamine-linked platinum-based antitumour complexes. Dalton Trans (2011) 0.77
Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin. Nucleic Acids Res (2004) 0.76
Investigations of the binding of [Pt2(DTBPA)Cl2](II) and [Pt2(TPXA)Cl2](II) to DNA via various cross-linking modes. Int J Mol Sci (2013) 0.75
Competitive formation of DNA linkage isomers by a trinuclear platinum complex and the influence of pre-association. Dalton Trans (2015) 0.75
Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes. Sci Rep (2016) 0.75
Antiangiogenic platinum through glycan targeting. Chem Sci (2016) 0.75
A dinuclear monofunctional platinum(II) complex with an aromatic linker shows low reactivity towards glutathione but high DNA binding ability and antitumor activity. J Biol Inorg Chem (2007) 0.75
In vitro antitumour and hepatotoxicity profiles of Au(I) and Ag(I) bidentate pyridyl phosphine complexes and relationships to cellular uptake. J Inorg Biochem (2007) 1.84
Targeting retroviral Zn finger-DNA interactions: a small-molecule approach using the electrophilic nature of trans-platinum-nucleobase compounds. Chem Biol (2006) 1.47
Mitochondrial permeability transition induced by dinuclear gold(I)-carbene complexes: potential new antimitochondrial antitumour agents. J Inorg Biochem (2004) 1.41
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. J Biol Chem (2002) 1.28
Mitochondria-targeted chemotherapeutics: the rational design of gold(I) N-heterocyclic carbene complexes that are selectively toxic to cancer cells and target protein selenols in preference to thiols. J Am Chem Soc (2008) 1.23
Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity. J Biol Inorg Chem (2004) 1.18
A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464. J Biol Inorg Chem (2002) 1.04
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors. Free Radic Biol Med (2010) 1.02
Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [(trans-PtCl(NH(3))(2))(2)(mu-trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2))](4+) (BBR3464). Inorg Chem (2002) 1.01
Biological consequences of trinuclear platinum complexes: comparison of [[trans-PtCl(NH3)2]2mu-(trans-Pt(NH3)2(H2N(CH2)6-NH2)2)]4+ (BBR 3464) with its noncovalent congeners. Mol Pharmacol (2005) 1.00
Cationic, linear Au(I) N-heterocyclic carbene complexes: synthesis, structure and anti-mitochondrial activity. Dalton Trans (2006) 1.00
DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts. Biochemistry (2003) 0.97
A gold(I) phosphine complex selectively induces apoptosis in breast cancer cells: implications for anticancer therapeutics targeted to mitochondria. Biochem Pharmacol (2007) 0.97
Reaction of polynuclear platinum antitumor compounds with reduced glutathione studied by multinuclear (1H, 1H-15N gradient heteronuclear single-quantum coherence, and 195Pt) NMR spectroscopy. Inorg Chem (2003) 0.96
Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents. Biochemistry (2004) 0.95
Ligand effects on the binding of cis- and trans-[PtCl(2)Am(1)Am(2)] to proteins. J Biol Inorg Chem (2002) 0.93
NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound. Chem Commun (Camb) (2013) 0.93
Luminescence studies of the intracellular distribution of a dinuclear gold(I) N-heterocyclic carbene complex. Angew Chem Int Ed Engl (2006) 0.92
Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer. Chemistry (2009) 0.92
Effects of geometric isomerism in dinuclear platinum antitumor complexes on aquation reactions in the presence of perchlorate, acetate and phosphate. J Biol Inorg Chem (2005) 0.92
Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)]. Nucleic Acids Res (2005) 0.90
Unique cooperative binding interaction observed between a minor groove binding Pt antitumor agent and Hoechst dye 33258. Inorg Chem (2005) 0.89
Effects of geometric isomerism in dinuclear antitumor platinum complexes on their interactions with N-acetyl-L-methionine. J Biol Inorg Chem (2005) 0.88
Differences in the cellular response and signaling pathways of cisplatin and BBR3464 ([[trans-PtCl(NH3)(2)]2mu-(trans-Pt(NH3)(2)(H2N(CH2)(6)-NH2)2)]4+) influenced by copper homeostasis. Biochem Pharmacol (2006) 0.88
trans-Platinum planar amine compounds with [N2O2] ligand donor sets: effects of carboxylate leaving groups and steric hindrance on chemical and biological properties. Inorg Chem (2006) 0.87
Enhancement of aqueous solubility and stability employing a trans acetate axis in trans planar amine platinum compounds while maintaining the biological profile. J Med Chem (2005) 0.87
Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes. Chemistry (2008) 0.85
Determination of the kinetic profile of a dinuclear platinum anticancer complex in the presence of sulfate: introducing a new tool for the expedited analysis of 2D [(1)H,( 15)N] HSQC NMR spectra. Inorg Chem (2010) 0.85
Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes. J Inorg Biochem (2004) 0.85
Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound. Carcinogenesis (2008) 0.85
Differences in breast cancer diagnosis and treatment: experiences of insured and uninsured women in a safety-net setting. Inquiry (2008) 0.85
An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex. Food Chem (2012) 0.85
Deoxyribonuclease I footprinting reveals different DNA binding modes of bifunctional platinum complexes. FEBS J (2006) 0.84
Visualising gold inside tumour cells following treatment with an antitumour gold(I) complex. Metallomics (2011) 0.84
Synthesis and DNA conformational changes of non-covalent polynuclear platinum complexes. J Inorg Biochem (2004) 0.84
Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes. Dalton Trans (2009) 0.84
Circular dichroism study of the irreversibility of conformational changes induced by polyamine-linked dinuclear platinum compounds. J Inorg Biochem (2002) 0.83
A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding. Chem Commun (Camb) (2014) 0.83
Novel transplatinum(II) complexes with [N2O2] donor sets. Cellular pharmacology and apoptosis induction in Pam 212-ras cells. J Med Chem (2006) 0.83
Diversity in guanine-selective DNA binding modes for an organometallic ruthenium arene complex. Angew Chem Int Ed Engl (2006) 0.82
[1H, 15N] heteronuclear single quantum coherence NMR study of the mechanism of aquation of platinum(IV) ammine complexes. Inorg Chem (2008) 0.82
A surprisingly stable macrochelate formed from the reaction of cis dinuclear platinum antitumor compounds with reduced glutathione. Inorg Chem (2005) 0.82
Chimeric platinum-polyamines and DNA binding. Kinetics of DNA interstrand cross-link formation by dinuclear platinum complexes with polyamine linkers. J Am Chem Soc (2012) 0.82
Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding. J Inorg Biochem (2004) 0.82
Platination of nucleobases to enhance noncovalent recognition in protein-DNA/RNA complexes. Inorg Chem (2005) 0.82
Nonclassic metallointercalators with dipyridophenazine: DNA interaction studies and leishmanicidal activity. Inorg Chem (2013) 0.81
1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin. Arch Biochem Biophys (2006) 0.80
Pyridine-carboxylate complexes of platinum. Effect of N,O-chelate formation on model bifunctional DNA-DNA and DNA-protein interactions. Inorg Chem (2005) 0.80
Mechanism of the membrane interaction of polynuclear platinum anticancer agents. Implications for cellular uptake. Biochemistry (2006) 0.79
Stereoselective fluorination alters the geometry of a cyclic peptide: exploration of backbone-fluorinated analogues of unguisin A. Angew Chem Int Ed Engl (2014) 0.79
Dinuclear gold(I) complexes of bridging bidentate carbene ligands: synthesis, structure and spectroscopic characterisation. Dalton Trans (2004) 0.78
Modulation of Nucleotide Binding of trans Platinum(II) Complexes by Planar Ligands. A Combined Proton NMR and Molecular Mechanics Study. Inorg Chem (1997) 0.78
Gold(I) chloride adducts of 1,3-bis(di-2-pyridylphosphino)propane: synthesis, structural studies and antitumour activity. Dalton Trans (2007) 0.78
Competitive formation of both long-range 5'-5' and short-range antiparallel 3'-3' DNA interstrand cross-links by a trinuclear platinum complex on binding to a 10-mer duplex. Dalton Trans (2012) 0.78
The nature of the DNA template (single- versus double-stranded) affects the rate of aquation of a dinuclear Pt anticancer drug. Chem Commun (Camb) (2003) 0.78
Solution studies of dinuclear polyamine-linked platinum-based antitumour complexes. Dalton Trans (2011) 0.77
1 : 2 Adducts of copper(I) halides with 1,2-bis(di-2-pyridylphosphino)ethane: solid state and solution structural studies and antitumour activity. Dalton Trans (2009) 0.77
Greater binding affinity of trivalent antimony to a CCCH zinc finger domain compared to a CCHC domain of kinetoplastid proteins. Metallomics (2012) 0.76
Differential recognition by the tumor suppressor protein p53 of DNA modified by the novel antitumor trinuclear platinum drug BBR3464 and cisplatin. Nucleic Acids Res (2004) 0.76
Thiolate-bridged heterodinuclear platinum-zinc chelates as models for ternary platinum-DNA-protein complexes and zinc ejection from zinc fingers. Evidence from studies using ESI-mass spectrometry. Chem Commun (Camb) (2005) 0.76
Tuning the reactivity of Sp1 zinc fingers with platinum complexes. Dalton Trans (2016) 0.75
The solution structure of bis(phenazine-1-carboxamide)-DNA complexes: MLN 944 binding corrected and extended. Biopolymers (2014) 0.75
Bromide ion binding by a dinuclear gold(I) N-heterocyclic carbene complex: a spectrofluorescence and X-ray absorption spectroscopic study. Dalton Trans (2013) 0.75
Multisite effects on intervalence charge transfer in a clusterlike trinuclear assembly containing ruthenium and osmium. Inorg Chem (2006) 0.75
Preface for the JIB Special Issue on Latin American Bioinorganic Chemistry. J Inorg Biochem (2014) 0.75
Underlying spin-orbit coupling structure of intervalence charge transfer bands in dinuclear polypyridyl complexes of ruthenium and osmium. Inorg Chem (2006) 0.75
Putting corannulene in its place. Reactivity studies comparing corannulene with other aromatic hydrocarbons. Org Biomol Chem (2015) 0.75