Published in J Gen Virol on December 01, 2002
Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines. Cell Host Microbe (2008) 1.94
The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling. J Biol Chem (2003) 1.93
High-throughput phosphotyrosine profiling using SH2 domains. Mol Cell (2007) 1.72
Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA. J Virol (2008) 1.58
Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly. Structure (2012) 1.47
Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proc Natl Acad Sci U S A (2009) 1.46
Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome. EMBO Rep (2006) 1.33
SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication. PLoS Pathog (2011) 1.32
Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling. J Biol Chem (2007) 1.22
Primary cutaneous T-cell lymphomas show a deletion or translocation affecting NAV3, the human UNC-53 homologue. Cancer Res (2005) 1.12
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proc Natl Acad Sci U S A (2009) 1.12
HIV-1 Nef interacts with inositol trisphosphate receptor to activate calcium signaling in T cells. J Exp Med (2002) 1.08
A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors. J Cell Sci (2008) 1.06
Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon. J Immunol (2007) 1.05
Dystroglycan, Tks5 and Src mediated assembly of podosomes in myoblasts. PLoS One (2008) 1.05
Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors. J Virol (2004) 1.05
Further studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling. J Gen Virol (2005) 1.04
Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly. Proc Natl Acad Sci U S A (2010) 1.04
Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan. J Cell Sci (2010) 1.03
Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly. Traffic (2011) 1.02
Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage. Mol Immunol (2004) 1.01
Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. J Virol (2004) 0.97
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases. Mol Cell (2013) 0.96
Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes. Mol Cell Biol (2012) 0.95
Role of the Kaposi's sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation. J Virol (2010) 0.91
Attenuation of Semliki Forest virus neurovirulence by microRNA-mediated detargeting. J Virol (2012) 0.91
The mechanism of tissue-restricted antigen gene expression by AIRE. J Immunol (2013) 0.90
Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis. J Biol Chem (2013) 0.88
Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription. Nucleic Acids Res (2011) 0.88
MicroRNA-mediated suppression of oncolytic adenovirus replication in human liver. PLoS One (2013) 0.88
Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB. Virology (2003) 0.88
Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function. Retrovirology (2012) 0.87
Structural basis of PxxDY motif recognition in SH3 binding. J Mol Biol (2008) 0.87
Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice. J Biol Chem (2005) 0.86
Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions. J Virol (2012) 0.86
Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation. Mol Cell Biol (2002) 0.85
Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins. J Cell Biochem (2009) 0.83
High-affinity target binding engineered via fusion of a single-domain antibody fragment with a ligand-tailored SH3 domain. PLoS One (2012) 0.82
Versatile retargeting of SH3 domain binding by modification of non-conserved loop residues. FEBS Lett (2007) 0.82
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. PLoS One (2012) 0.81
Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody. Retrovirology (2014) 0.78
Optimized mouse model for the imaging of tumor metastasis upon experimental therapy. PLoS One (2011) 0.78
A single-chain antibody/epitope system for functional analysis of protein-protein interactions. Biochemistry (2002) 0.77
Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms. Retrovirology (2013) 0.75