Published in Cancer on December 15, 2002
Vascular smooth muscle cell motility: From migration to invasion. Exp Clin Cardiol (2010) 1.33
Molecular targets for tumour progression in gastrointestinal stromal tumours. Gut (2004) 1.22
Focal adhesion kinase as a cancer therapy target. Anticancer Agents Med Chem (2010) 1.19
Essentials of oral cancer. Int J Clin Exp Pathol (2015) 1.05
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol Cancer (2010) 0.92
SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma. BMC Clin Pathol (2010) 0.90
Focal adhesion kinase is activated in invading fibrosarcoma cells and regulates metastasis. Clin Exp Metastasis (2005) 0.90
Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells. Lab Invest (2016) 0.87
Focal adhesion kinase and Src phosphorylations in HGF-induced proliferation and invasion of human cholangiocarcinoma cell line, HuCCA-1. World J Gastroenterol (2005) 0.86
Focal adhesion kinase serves as a marker of cervical lymph node metastasis and is a potential therapeutic target in tongue cancer. J Cancer Res Clin Oncol (2010) 0.80
Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. J Invest Dermatol (2011) 0.80
Expression of FAK-related non-kinase (FRNK) coincides with morphological change in the early stage of cell adhesion. Med Mol Morphol (2006) 0.77
Expression of pY397 FAK promotes the development of non-small cell lung cancer. Oncol Lett (2015) 0.76
A Case-Control Study of Comparison of Plasma Levels of Matrix Metalloproteinase-9 in Inhaled Opium Addicts and Clinically Healthy Persons. Addict Health (2017) 0.75
Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med (2006) 4.54
MAP kinases and cell migration. J Cell Sci (2004) 4.46
JNK phosphorylates paxillin and regulates cell migration. Nature (2003) 3.60
The interplay between Src and integrins in normal and tumor biology. Oncogene (2004) 3.37
Structural basis for the autoinhibition of focal adhesion kinase. Cell (2007) 3.18
A molecular role for lysyl oxidase in breast cancer invasion. Cancer Res (2002) 2.65
Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells. Proc Natl Acad Sci U S A (2008) 2.51
FAK regulates biological processes important for the pathogenesis of cancer. Cancer Metastasis Rev (2003) 2.48
Paradoxical roles for lysyl oxidases in cancer--a prospect. J Cell Biochem (2007) 2.30
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Res (2005) 2.27
Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion. Am J Pathol (2004) 2.12
Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest (2010) 2.04
Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications. Am J Pathol (2007) 1.99
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism. Cancer Res (2005) 1.95
Maspin regulates different signaling pathways for motility and adhesion in aggressive breast cancer cells. Cancer Biol Ther (2003) 1.85
The fate of human malignant melanoma cells transplanted into zebrafish embryos: assessment of migration and cell division in the absence of tumor formation. Dev Dyn (2005) 1.78
Science policy. The NIH budget in the "postdoubling" era. Science (2002) 1.74
Spatial and temporal regulation of focal adhesion kinase activity in living cells. Mol Cell Biol (2007) 1.72
The paradoxical expression of maspin in ovarian carcinoma. Clin Cancer Res (2002) 1.71
A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src. Curr Biol (2003) 1.67
Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment. Proc Natl Acad Sci U S A (2006) 1.67
Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells. Clin Cancer Res (2005) 1.63
The clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer. Clin Cancer Res (2006) 1.59
Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility. J Biol Chem (2005) 1.58
Tumor cell vasculogenic mimicry: from controversy to therapeutic promise. Am J Pathol (2012) 1.58
Preoperative serum vascular endothelial growth factor levels: significance in ovarian cancer. Clin Cancer Res (2002) 1.57
Crystal structure of the FERM domain of focal adhesion kinase. J Biol Chem (2005) 1.57
Reevaluating cathepsin D as a biomarker for breast cancer: serum activity levels versus histopathology. Cancer Biol Ther (2010) 1.55
Biological functions of maspin. J Cell Physiol (2006) 1.54
Molecular pathways: vasculogenic mimicry in tumor cells: diagnostic and therapeutic implications. Clin Cancer Res (2012) 1.52
Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry. Cancer Res (2003) 1.50
Molecular determinants of human uveal melanoma invasion and metastasis. Clin Exp Metastasis (2002) 1.50
Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch. J Cell Biol (2003) 1.49
Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype. Cancer Res (2010) 1.49
Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells. J Natl Cancer Inst (2004) 1.49
Maspin regulates hypoxia-mediated stimulation of uPA/uPAR complex in invasive breast cancer cells. Cancer Biol Ther (2005) 1.49
Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer Res (2005) 1.49
Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership. J Biol Chem (2005) 1.44
Differential regulation of EphA2 in normal and malignant cells. Am J Pathol (2003) 1.43
Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration. J Cell Biochem (2008) 1.41
p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma. Cancer Biol Ther (2002) 1.41
VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry. Cancer Biol Ther (2006) 1.41
p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol Cancer Ther (2004) 1.40
Transendothelial function of human metastatic melanoma cells: role of the microenvironment in cell-fate determination. Cancer Res (2002) 1.36
ErbB/EGF signaling and EMT in mammary development and breast cancer. J Mammary Gland Biol Neoplasia (2010) 1.36
Differential role of tissue factor pathway inhibitors 1 and 2 in melanoma vasculogenic mimicry. Cancer Res (2003) 1.35
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells. Prostate (2011) 1.34
FERM domain interaction promotes FAK signaling. Mol Cell Biol (2004) 1.34
Expression of multiple molecular phenotypes by aggressive melanoma tumor cells: role in vasculogenic mimicry. Crit Rev Oncol Hematol (2002) 1.32
Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: role in vasculogenic mimicry. Prostate (2002) 1.32
Development and cancer: at the crossroads of Nodal and Notch signaling. Cancer Res (2009) 1.30
Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement. Mol Cell Biol (2006) 1.26
A three-dimensional model to study the epigenetic effects induced by the microenvironment of human embryonic stem cells. Stem Cells (2005) 1.26
PTP-PEST controls motility through regulation of Rac1. J Cell Sci (2002) 1.24
Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner. Mol Cell Biol (2008) 1.22
Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment. Epigenomics (2009) 1.22
Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res (2005) 1.22
Maspin: molecular mechanisms and therapeutic implications. Cancer Metastasis Rev (2012) 1.21
Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer. Breast Cancer Res (2012) 1.21
Potential for cripto-1 in defining stem cell-like characteristics in human malignant melanoma. Cell Cycle (2008) 1.20
Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'. Biochem J (2002) 1.20
Functional role of matrix metalloproteinases in ovarian tumor cell plasticity. Am J Obstet Gynecol (2004) 1.20
Focal adhesion kinase: exploring Fak structure to gain insight into function. Int Rev Cell Mol Biol (2011) 1.19
Multiple paxillin binding sites regulate FAK function. J Mol Signal (2008) 1.19
The effect of hydrogel charge density on cell attachment. Biomaterials (2004) 1.19
Influence of the microenvironment on melanoma cell fate determination and phenotype. Cancer Res (2006) 1.18
Reprogramming multipotent tumor cells with the embryonic neural crest microenvironment. Dev Dyn (2008) 1.18
NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model. J Biol Chem (2003) 1.17
A model of cancer stem cells derived from mouse induced pluripotent stem cells. PLoS One (2012) 1.17
Deciphering the signaling events that promote melanoma tumor cell vasculogenic mimicry and their link to embryonic vasculogenesis: role of the Eph receptors. Dev Dyn (2007) 1.16
The clinical significance of tumor cell-lined vasculature in ovarian carcinoma: implications for anti-vasculogenic therapy. Cancer Biol Ther (2003) 1.15
Severe feto-placental abnormalities precede the onset of hypertension and proteinuria in a mouse model of preeclampsia. Biol Reprod (2006) 1.12
New insights into FAK signaling and localization based on detection of a FAT domain folding intermediate. Structure (2004) 1.11
Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells. J Cell Biol (2004) 1.11
Effects of implant surface microtopography on osteoblast gene expression. Clin Oral Implants Res (2005) 1.09
Lipid binding to the tail domain of vinculin: specificity and the role of the N and C termini. J Biol Chem (2008) 1.09
A requirement for dimerization of HP1Hsalpha in suppression of breast cancer invasion. J Biol Chem (2006) 1.08
Embryonic signaling in melanoma: potential for diagnosis and therapy. Lab Invest (2011) 1.07
A role for JNK-paxillin signaling in cell migration. Cell Cycle (2004) 1.07
Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Res (2005) 1.06
Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex. J Cell Biochem (2006) 1.06
Targeting Nodal in malignant melanoma cells. Expert Opin Ther Targets (2007) 1.05
Aberrant methylation of the maspin promoter is an early event in human breast cancer. Neoplasia (2004) 1.05
PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells. Am J Physiol Cell Physiol (2010) 1.04
CIB1 regulates endothelial cells and ischemia-induced pathological and adaptive angiogenesis. Circ Res (2007) 1.04
Focal adhesion kinase regulates cell-cell contact formation in epithelial cells via modulation of Rho. Exp Cell Res (2008) 1.04
Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression. Breast Dis (2008) 1.03
Differentiation of preosteoblasts is affected by implant surface microtopographies. J Biomed Mater Res A (2004) 1.03
IFN-gamma regulation of vacuolar pH, cathepsin D processing and autophagy in mammary epithelial cells. J Cell Biochem (2008) 1.02