Published in Eukaryot Cell on December 01, 2002
Spatial patterns of DNA replication, protein synthesis, and oxygen concentration within bacterial biofilms reveal diverse physiological states. J Bacteriol (2007) 1.96
Cell biology of the trypanosome genome. Microbiol Mol Biol Rev (2010) 1.27
Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea. Eukaryot Cell (2009) 1.14
Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryot Cell (2005) 1.06
Genome size, karyotype polymorphism and chromosomal evolution in Trypanosoma cruzi. PLoS One (2011) 0.95
Distinct acetylation of Trypanosoma cruzi histone H4 during cell cycle, parasite differentiation, and after DNA damage. Chromosoma (2009) 0.80
Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery. Nucleus (2011) 0.79
Unveiling the effects of berenil, a DNA-binding drug, on Trypanosoma cruzi: implications for kDNA ultrastructure and replication. Parasitol Res (2014) 0.78
Unveiling the Trypanosoma cruzi Nuclear Proteome. PLoS One (2015) 0.77
Histone H1 of Trypanosoma cruzi is concentrated in the nucleolus region and disperses upon phosphorylation during progression to mitosis. Eukaryot Cell (2008) 0.77
The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycle. BMC Microbiol (2009) 0.76
Effects of camptothecin derivatives and topoisomerase dual inhibitors on Trypanosoma cruzi growth and ultrastructure. J Negat Results Biomed (2014) 0.75
Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi. PLoS Negl Trop Dis (2016) 0.75
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature (2001) 19.67
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature (2001) 19.54
Structure and function in the nucleus. Science (1998) 6.26
Macromolecular domains within the cell nucleus. Annu Rev Cell Biol (1993) 5.90
Dynamics of DNA replication factories in living cells. J Cell Biol (2000) 4.93
Chromosome dynamics in the yeast interphase nucleus. Science (2001) 4.33
GROWTH AND DIFFERENTIATION IN TRYPANOSOMA CRUZI. I. ORIGIN OF METACYCLIC TRYPANOSOMES IN LIQUID MEDIA. Rev Inst Med Trop Sao Paulo (1964) 4.09
Visualization of replication factories attached to nucleoskeleton. Cell (1993) 3.36
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases. Nat Cell Biol (2001) 3.34
Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus. Exp Cell Res (1986) 3.17
Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci (1990) 3.16
Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells. J Cell Biol (1996) 2.61
Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR. J Biol Chem (1997) 2.58
Spatial and temporal dynamics of DNA replication sites in mammalian cells. J Cell Biol (1998) 2.32
Functional architecture in the cell nucleus. Biochem J (2001) 2.28
Nuclear organization of mammalian genomes. Polar chromosome territories build up functionally distinct higher order compartments. J Cell Biol (1999) 2.19
Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: precise choreography of condensation/decondensation and nuclear positioning. J Cell Biol (1998) 2.10
Spatial organization of large-scale chromatin domains in the nucleus: a magnified view of single chromosome territories. J Cell Biol (1997) 1.94
Chromosome territories, interchromatin domain compartment, and nuclear matrix: an integrated view of the functional nuclear architecture. Crit Rev Eukaryot Gene Expr (2000) 1.86
Chromo-domain proteins: linking chromatin structure to epigenetic regulation. Curr Opin Cell Biol (1998) 1.78
Cell cycle dependent chromosomal movement in pre-mitotic human T-lymphocyte nuclei. Chromosoma (1992) 1.71
Minichromosomal repetitive DNA in Trypanosoma cruzi: its use in a high-sensitivity parasite detection assay. Proc Natl Acad Sci U S A (1984) 1.65
Disruption of nuclear lamin organization blocks the elongation phase of DNA replication. J Cell Biol (2000) 1.64
Inhibition of DNA synthesis by hydroxyurea: structure-activity relationships. Cancer Res (1967) 1.60
Molecular karyotype of clone CL Brener chosen for the Trypanosoma cruzi genome project. Mol Biochem Parasitol (1995) 1.48
Association of chromosome territories with the nuclear matrix. Disruption of human chromosome territories correlates with the release of a subset of nuclear matrix proteins. J Cell Biol (1999) 1.40
Organization of early and late replicating DNA in human chromosome territories. Exp Cell Res (1999) 1.31
Allosteric regulation of Trypanosoma brucei ribonucleotide reductase studied in vitro and in vivo. J Biol Chem (1998) 1.30
Transcription rate modulation through the Trypanosoma cruzi life cycle occurs in parallel with changes in nuclear organisation. Mol Biochem Parasitol (2001) 1.19
Nuclear organization and silencing: putting things in their place. Nat Cell Biol (2002) 1.14
PARP gene expression: control at many levels. Mol Biochem Parasitol (1998) 1.08
From snapshots to moving pictures: new perspectives on nuclear organization. Trends Cell Biol (2001) 0.99
Expression of trans-sialidase and 85-kDa glycoprotein genes in Trypanosoma cruzi is differentially regulated at the post-transcriptional level by labile protein factors. J Biol Chem (1999) 0.95
Control of gene expression in Trypanosomatidae. Braz J Med Biol Res (1998) 0.92
Hydroxyurea-induced synchrony of DNA replication in the Kinetoplastida. Exp Cell Res (1994) 0.92
Review: nuclear structure and DNA replication. J Struct Biol (2000) 0.91
The influence of hydroxyurea and colchicine on growth and morphology of Trypanosoma cruzi. Acta Trop (1978) 0.89
Identification of the telomere in Trypanosoma cruzi reveals highly heterogeneous telomere lengths in different parasite strains. Nucleic Acids Res (1999) 0.88
Direct evidence for interphase chromosome movement during the mid-blastula transition in Drosophila. Curr Biol (2000) 0.84
Physical mapping of a 670-kb region of chromosomes XVI and XVII from the human protozoan parasite Trypanosoma cruzi encompassing the genes for two immunodominant antigens. Genome Res (1999) 0.84
Highly sensitive immunodetection of DNA on sections with exogenous terminal deoxynucleotidyl transferase and non-isotopic nucleotide analogues. J Histochem Cytochem (1992) 0.83
Labeling of Crithidia fasciculata DNA with (3H)thymidine. J Protozool (1974) 0.81
The requirements for G1 checkpoint progression of Trypanosoma brucei S 427 clone 1. Mol Biochem Parasitol (1996) 0.81
Acidocalcisomes - conserved from bacteria to man. Nat Rev Microbiol (2005) 2.46
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. J Clin Invest (2013) 1.80
Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion. J Exp Med (2011) 1.80
CD4+CD25+ T cells in skin lesions of patients with cutaneous leishmaniasis exhibit phenotypic and functional characteristics of natural regulatory T cells. J Infect Dis (2006) 1.77
Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplication. BMC Mol Biol (2007) 1.64
Characterization of a novel organelle in Toxoplasma gondii with similar composition and function to the plant vacuole. Mol Microbiol (2010) 1.61
Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium. Antimicrob Agents Chemother (2005) 1.60
Diterpenoids from Azorella compacta (Umbelliferae) active on Trypanosoma cruzi. Mem Inst Oswaldo Cruz (2003) 1.59
Modeling lymphangiogenesis in a three-dimensional culture system. Nat Methods (2008) 1.55
Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3. J Biol Chem (2001) 1.49
The nucleolus: structure/function relationship in RNA metabolism. Wiley Interdiscip Rev RNA (2010) 1.37
Proliferative generation of mammalian auditory hair cells in culture. Mech Dev (2002) 1.29
Trypanosoma cruzi: parasite shed vesicles increase heart parasitism and generate an intense inflammatory response. Microbes Infect (2008) 1.28
In vitro activity of essential oil from Ocimum gratissimum L. against four Candida species. Res Microbiol (2004) 1.22
Novel membrane-bound eIF2alpha kinase in the flagellar pocket of Trypanosoma brucei. Eukaryot Cell (2007) 1.16
Novel types of mutation responsible for the dermatosparactic type of Ehlers-Danlos syndrome (Type VIIC) and common polymorphisms in the ADAMTS2 gene. J Invest Dermatol (2004) 1.16
Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea. Eukaryot Cell (2009) 1.14
Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. J Med Chem (2003) 1.12
Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. Antimicrob Agents Chemother (2004) 1.12
Toxoplasma gondii partially inhibits nitric oxide production of activated murine macrophages. Exp Parasitol (2002) 1.12
Post-translational modifications of Trypanosoma cruzi histone H4. Mol Biochem Parasitol (2006) 1.12
Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells. Parasitol Res (2013) 1.10
Organization of satellite DNA in the genome of Trypanosoma cruzi. Mol Biochem Parasitol (2003) 1.10
Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development (2013) 1.07
Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole. Cell Microbiol (2006) 1.06
Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryot Cell (2005) 1.06
Sterol methenyl transferase inhibitors alter the ultrastructure and function of the Leishmania amazonensis mitochondrion leading to potent growth inhibition. Protist (2007) 1.06
Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei. J Biol Chem (2010) 1.05
P2X1 ion channels promote neutrophil chemotaxis through Rho kinase activation. J Immunol (2009) 1.05
Itraconazole affects Toxoplasma gondii endodyogeny. FEMS Microbiol Lett (2008) 1.05
Morphological events during the Trypanosoma cruzi cell cycle. Protist (2006) 1.05
LFR1 ferric iron reductase of Leishmania amazonensis is essential for the generation of infective parasite forms. J Biol Chem (2011) 1.05
Tamoxifen is effective against Leishmania and induces a rapid alkalinization of parasitophorous vacuoles harbouring Leishmania (Leishmania) amazonensis amastigotes. J Antimicrob Chemother (2007) 1.04
The small nucle(ol)ar RNA cap trimethyltransferase is required for ribosome synthesis and intact nucleolar morphology. Mol Cell Biol (2004) 1.04
All Trypanosoma cruzi developmental forms present lysosome-related organelles. Histochem Cell Biol (2008) 1.03
Antiproliferative, Ultrastructural, and Physiological Effects of Amiodarone on Promastigote and Amastigote Forms of Leishmania amazonensis. Mol Biol Int (2011) 1.03
ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-induced hepatic fibrosis in mice. Hepatology (2007) 1.03
Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle. Mol Biochem Parasitol (2005) 1.02
Mouse resident peritoneal macrophages partially control in vitro infection with Coxiella burnetii phase II. Microbes Infect (2002) 1.01
Biology of human pathogenic trypanosomatids: epidemiology, lifecycle and ultrastructure. Subcell Biochem (2014) 1.00
Calcium ionophore-induced egress of Toxoplasma gondii shortly after host cell invasion. Vet Parasitol (2007) 1.00
In vitro activities of ER-119884 and E5700, two potent squalene synthase inhibitors, against Leishmania amazonensis: antiproliferative, biochemical, and ultrastructural effects. Antimicrob Agents Chemother (2008) 1.00
Co-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitro. Immunology (2008) 0.99
Characterization of a 21kDa protein from Trypanosoma cruzi associated with mammalian cell invasion. Microbes Infect (2009) 0.99
Functional genomic characterization of mRNAs associated with TcPUF6, a pumilio-like protein from Trypanosoma cruzi. J Biol Chem (2007) 0.99
Three-dimensional organization of active rRNA genes within the nucleolus. J Cell Sci (2002) 0.98
Ultrastructural alterations in organelles of parasitic protozoa induced by different classes of metabolic inhibitors. Curr Pharm Des (2008) 0.98
Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi. Int J Antimicrob Agents (2012) 0.98
Increased association of Trypanosoma cruzi with sialoadhesin positive mice macrophages. Parasitol Res (2005) 0.98
Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers. BMC Evol Biol (2013) 0.98
Effect of alkylphospholipids on Candida albicans biofilm formation and maturation. J Antimicrob Chemother (2012) 0.97
Subcellular proteomics of Trypanosoma cruzi reservosomes. Proteomics (2009) 0.97
Trypanosoma cruzi: ultrastructural studies of adhesion, lysis and biofilm formation by Serratia marcescens. Exp Parasitol (2007) 0.97
Antiproliferative and ultrastructural effects of BPQ-OH, a specific inhibitor of squalene synthase, on Leishmania amazonensis. Exp Parasitol (2005) 0.97
Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms. PLoS One (2011) 0.97
HIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis. PLoS One (2009) 0.97
Structural changes of the paraflagellar rod during flagellar beating in Trypanosoma cruzi. PLoS One (2010) 0.97
Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment. Clin Diagn Lab Immunol (2003) 0.96
Acidocalcisomes in Apicomplexan parasites. Exp Parasitol (2007) 0.96
Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase. Blood (2012) 0.96
Toxoplasma gondii exposes phosphatidylserine inducing a TGF-beta1 autocrine effect orchestrating macrophage evasion. Biochem Biophys Res Commun (2004) 0.96
Melanin in Fonsecaea pedrosoi: a trap for oxidative radicals. BMC Microbiol (2010) 0.96
Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa. Eukaryot Cell (2005) 0.95
Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family. PLoS One (2013) 0.95
Reservosomes: multipurpose organelles? Parasitol Res (2006) 0.94
Natural killer cells: role in local tumor growth and metastasis. Biologics (2012) 0.94
Trypanosoma cruzi exposes phosphatidylserine as an evasion mechanism. FEMS Microbiol Lett (2006) 0.94
Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol (2009) 0.94
Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. J Neurochem (2010) 0.93
A novel protein phosphatase 2A (PP2A) is involved in the transformation of human protozoan parasite Trypanosoma cruzi. Biochem J (2003) 0.93
Ultrastructural characterization of melanosomes of the human pathogenic fungus Fonsecaea pedrosoi. J Struct Biol (2007) 0.93
The diverse and dynamic nature of Leishmania parasitophorous vacuoles studied by multidimensional imaging. PLoS Negl Trop Dis (2012) 0.93
Lectin KM+-induced neutrophil haptotaxis involves binding to laminin. Biochim Biophys Acta (2004) 0.93
In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease. Antimicrob Agents Chemother (2010) 0.93
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Org Biomol Chem (2011) 0.93
Trypanosoma livingstonei: a new species from African bats supports the bat seeding hypothesis for the Trypanosoma cruzi clade. Parasit Vectors (2013) 0.93
Comparative analysis of genomic sequences suggests that Trypanosoma cruzi CL Brener contains two sets of non-intercalated repeats of satellite DNA that correspond to T. cruzi I and T. cruzi II types. Mol Biochem Parasitol (2005) 0.92
Chagas' disease: facts and reality. Microbes Infect (2007) 0.92
Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi. Biochem J (2005) 0.92
Antiproliferative activities of two novel quinuclidine inhibitors against Toxoplasma gondii tachyzoites in vitro. J Antimicrob Chemother (2006) 0.92
Homology, paralogy and function of DGF-1, a highly dispersed Trypanosoma cruzi specific gene family and its implications for information entropy of its encoded proteins. Mol Biochem Parasitol (2009) 0.92
Conditional knockout of nucleolin in DT40 cells reveals the functional redundancy of its RNA-binding domains. Biol Cell (2009) 0.92
Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. Eur J Immunol (2011) 0.92
Structural and functional organization of ribosomal genes within the mammalian cell nucleolus. J Histochem Cytochem (2005) 0.91
Interrelations between the parasitophorous vacuole of Toxoplasma gondii and host cell organelles. Microsc Microanal (2005) 0.91
Cell invasion by Trypanosoma cruzi amastigotes of distinct infectivities: studies on signaling pathways. Parasitol Res (2006) 0.91
Comparison of Fonsecaea pedrosoi sclerotic cells obtained in vivo and in vitro: ultrastructure and antigenicity. FEMS Immunol Med Microbiol (2002) 0.91
Bacterial community composition shifts in the gut of Periplaneta americana fed on different lignocellulosic materials. Springerplus (2013) 0.91
Cell death and regeneration in the midgut of the mosquito, Culex quinquefasciatus. J Insect Physiol (2007) 0.91
Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. PLoS One (2011) 0.90
Differences in cell morphometry, cell wall topography and gp70 expression correlate with the virulence of Sporothrix brasiliensis clinical isolates. PLoS One (2013) 0.90
Small-subunit rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi. Eukaryot Cell (2006) 0.90
Calcium- and polyphosphate-containing acidocalcisomes in chicken egg yolk. Biol Cell (2010) 0.90
The flagellar attachment zone of Trypanosoma cruzi epimastigote forms. J Struct Biol (2005) 0.90