The Trypanosoma cruzi nucleic acid binding protein Tc38 presents changes in the intramitochondrial distribution during the cell cycle.

PubWeight™: 0.76‹?›

🔗 View Article (PMC 2654453)

Published in BMC Microbiol on February 11, 2009

Authors

María A Duhagon1, Lucía Pastro, José R Sotelo-Silveira, Leticia Pérez-Díaz, Dante Maugeri, Sheila C Nardelli, Sergio Schenkman, Noreen Williams, Bruno Dallagiovanna, Beatriz Garat

Author Affiliations

1: Laboratorio de Interacciones Moleculares, Facultad de Ciencias, Montevideo, Uruguay. mduhagon@fcien.edu.uy

Articles cited by this

GROWTH AND DIFFERENTIATION IN TRYPANOSOMA CRUZI. I. ORIGIN OF METACYCLIC TRYPANOSOMES IN LIQUID MEDIA. Rev Inst Med Trop Sao Paulo (1964) 4.09

Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci (1990) 3.16

Fellowship of the rings: the replication of kinetoplast DNA. Trends Parasitol (2005) 2.21

In vitro differentiation of Trypanosoma cruzi under chemically defined conditions. Mol Biochem Parasitol (1985) 2.20

Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01

Replication of kinetoplast DNA in trypanosomes. Annu Rev Microbiol (1988) 1.91

An origin of DNA replication and a transcription silencer require a common element. Science (1992) 1.89

Inhibition of DNA synthesis by hydroxyurea: structure-activity relationships. Cancer Res (1967) 1.60

The structure and replication of kinetoplast DNA. Curr Mol Med (2004) 1.59

Intramitochondrial localization of universal minicircle sequence-binding protein, a trypanosomatid protein that binds kinetoplast minicircle replication origins. J Cell Biol (2001) 1.31

The replication mechanism of kinetoplast DNA networks in several trypanosomatid species. J Cell Sci (1998) 1.21

Role of p38 in replication of Trypanosoma brucei kinetoplast DNA. Mol Cell Biol (2006) 1.15

Molecular cloning of mtp70, a mitochondrial member of the hsp70 family. Mol Cell Biol (1989) 1.14

Kinetoplast maxicircle DNA replication in Crithidia fasciculata and Trypanosoma brucei. Mol Cell Biol (1995) 1.10

Morphological events during the Trypanosoma cruzi cell cycle. Protist (2006) 1.05

Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region. BMC Genomics (2006) 1.03

Cloning and characterization of the gene encoding Trypanosoma cruzi DNA topoisomerase II. Mol Biochem Parasitol (1992) 1.01

Chromosome localization changes in the Trypanosoma cruzi nucleus. Eukaryot Cell (2002) 0.94

Kinetoplastidae display naturally occurring ancillary DNA-containing structures. Mol Biochem Parasitol (1994) 0.93

Hydroxyurea-induced synchrony of DNA replication in the Kinetoplastida. Exp Cell Res (1994) 0.92

Cloning and characterization of a gene coding for a protein (KAP) associated with the kinetoplast of epimastigotes and amastigotes of Trypanosoma cruzi. Mol Biochem Parasitol (1990) 0.90

RBP38, a novel RNA-binding protein from trypanosomatid mitochondria, modulates RNA stability. Eukaryot Cell (2003) 0.90

Glycosomal and mitochondrial malate dehydrogenases in epimastigotes of Trypanosoma cruzi. Mol Biochem Parasitol (1984) 0.90

A simple method to purify biologically and antigenically preserved bloodstream trypomastigotes of Trypanosoma cruzi using DEAE-cellulose columns. Mem Inst Oswaldo Cruz (1984) 0.90

Trypanosoma cruzi: a gene family encoding chitin-binding-like proteins is posttranscriptionally regulated during metacyclogenesis. Exp Parasitol (2001) 0.89

The ribosomal RNA gene promoter and adjacent cis-acting DNA sequences govern plasmid DNA partitioning and stable inheritance in the parasitic protozoan Leishmania. Nucleic Acids Res (2004) 0.88

Characterization of the Trypanosoma cruzi Cdc2p-related protein kinase 1 and identification of three novel associating cyclins. Mol Biochem Parasitol (2001) 0.87

Trypanosoma cruzi: molecular characterization of TcPUF6, a Pumilio protein. Exp Parasitol (2005) 0.85

The pentose phosphate pathway in Trypanosoma cruzi. FEMS Microbiol Lett (2004) 0.84

Unusual features of poly[dT-dG].[dC-dA] stretches in CDS-flanking regions of Trypanosoma cruzi genome. Biochem Biophys Res Commun (2001) 0.82

Immunocytochemical localisation of calreticulin in Trypanosoma cruzi. Histochem Cell Biol (2004) 0.82

A novel type of single-stranded nucleic acid binding protein recognizing a highly frequent motif in the intergenic regions of Trypanosoma cruzi. Biochem Biophys Res Commun (2003) 0.80

Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand. Eur J Biochem (2004) 0.80

Sequence diversity in the kinetoplast DNA minicircles of Trypanosoma cruzi. Mol Biochem Parasitol (1986) 0.80

On the regulatory properties of the pyruvate kinase from Trypanosoma cruzi epimastigotes. FEMS Microbiol Lett (1989) 0.79

A single-stranded DNA-binding protein shared by telomeric repeats, the variant surface glycoprotein transcription promoter and the procyclin transcription terminator of Trypanosoma brucei. Nucleic Acids Res (2000) 0.78

LaRbp38: a Leishmania amazonensis protein that binds nuclear and kinetoplast DNAs. Biochem Biophys Res Commun (2007) 0.77

Kinetoplast DNA-binding protein profile in the epimastigote form of Trypanosoma cruzi. Arch Med Res (2002) 0.77

Identification of PDZ5, a candidate universal minicircle sequence binding protein of Trypanosoma cruzi. Int J Parasitol (2003) 0.76

Articles by these authors

Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae. J Bacteriol (2005) 2.15

ATP synthase is responsible for maintaining mitochondrial membrane potential in bloodstream form Trypanosoma brucei. Eukaryot Cell (2006) 1.39

Novel membrane-bound eIF2alpha kinase in the flagellar pocket of Trypanosoma brucei. Eukaryot Cell (2007) 1.16

Eukaryotic 5S rRNA biogenesis. Wiley Interdiscip Rev RNA (2011) 1.15

Trypanosome prereplication machinery contains a single functional orc1/cdc6 protein, which is typical of archaea. Eukaryot Cell (2009) 1.14

Post-translational modifications of Trypanosoma cruzi histone H4. Mol Biochem Parasitol (2006) 1.12

Organization of satellite DNA in the genome of Trypanosoma cruzi. Mol Biochem Parasitol (2003) 1.10

Two novel RNA binding proteins from Trypanosoma brucei are associated with 5S rRNA. Biochem Biophys Res Commun (2002) 1.08

Actively transcribing RNA polymerase II concentrates on spliced leader genes in the nucleus of Trypanosoma cruzi. Eukaryot Cell (2005) 1.06

Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole. Cell Microbiol (2006) 1.06

Target of rapamycin (TOR)-like 1 kinase is involved in the control of polyphosphate levels and acidocalcisome maintenance in Trypanosoma brucei. J Biol Chem (2010) 1.05

Morphological events during the Trypanosoma cruzi cell cycle. Protist (2006) 1.05

Ribosomal distributions in axons of mammalian myelinated fibers. J Neurosci Res (2007) 1.03

Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle. Mol Biochem Parasitol (2005) 1.02

Sinorhizobium meliloti fur-like (Mur) protein binds a fur box-like sequence present in the mntA promoter in a manganese-responsive manner. Appl Environ Microbiol (2007) 1.01

Characterization of a 21kDa protein from Trypanosoma cruzi associated with mammalian cell invasion. Microbes Infect (2009) 0.99

Co-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitro. Immunology (2008) 0.99

Functional genomic characterization of mRNAs associated with TcPUF6, a pumilio-like protein from Trypanosoma cruzi. J Biol Chem (2007) 0.99

Two trypanosome-specific proteins are essential factors for 5S rRNA abundance and ribosomal assembly in Trypanosoma brucei. Eukaryot Cell (2007) 0.98

Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms. PLoS One (2011) 0.97

Enzyme-linked immunoassay using recombinant trans-sialidase of Trypanosoma cruzi can be employed for monitoring of patients with Chagas' disease after drug treatment. Clin Diagn Lab Immunol (2003) 0.96

Vanadium polypyridyl compounds as potential antiparasitic and antitumoral agents: new achievements. J Inorg Biochem (2010) 0.96

Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family. PLoS One (2013) 0.95

Two families of RNA binding proteins from Trypanosoma brucei associate in a direct protein-protein interaction. Mol Biochem Parasitol (2002) 0.94

Assembly of the Trypanosoma brucei 60S ribosomal subunit nuclear export complex requires trypanosome-specific proteins P34 and P37. Eukaryot Cell (2008) 0.94

Chromosome localization changes in the Trypanosoma cruzi nucleus. Eukaryot Cell (2002) 0.94

Protein and mRNA content of TcDHH1-containing mRNPs in Trypanosoma cruzi. FEBS J (2010) 0.93

Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Org Biomol Chem (2011) 0.93

In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease. Antimicrob Agents Chemother (2010) 0.93

Chromatin modifications, epigenetics, and how protozoan parasites regulate their lives. Trends Parasitol (2012) 0.93

Comparative analysis of genomic sequences suggests that Trypanosoma cruzi CL Brener contains two sets of non-intercalated repeats of satellite DNA that correspond to T. cruzi I and T. cruzi II types. Mol Biochem Parasitol (2005) 0.92

Small-subunit rRNA processome proteins are translationally regulated during differentiation of Trypanosoma cruzi. Eukaryot Cell (2006) 0.90

Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Mem Inst Oswaldo Cruz (2012) 0.90

Trypanosoma brucei RNA binding proteins p34 and p37 mediate NOPP44/46 cellular localization via the exportin 1 nuclear export pathway. Eukaryot Cell (2007) 0.90

Are purified or expanded cord blood-derived CD133+ cells better at improving cardiac function? Exp Biol Med (Maywood) (2010) 0.90

T rypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas' disease. Cell Microbiol (2012) 0.90

TcZFP1: a CCCH zinc finger protein of Trypanosoma cruzi that binds poly-C oligoribonucleotides in vitro. Biochem Biophys Res Commun (2004) 0.89

Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA. PLoS One (2012) 0.88

Design of vanadium mixed-ligand complexes as potential anti-protozoa agents. J Inorg Biochem (2008) 0.88

Visual genome-wide RNAi screening to identify human host factors required for Trypanosoma cruzi infection. PLoS One (2011) 0.87

Stage-specific gene expression during Trypanosoma cruzi metacyclogenesis. Genet Mol Res (2003) 0.87

Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action. J Inorg Biochem (2009) 0.87

Trialysin, a novel pore-forming protein from saliva of hematophagous insects activated by limited proteolysis. J Biol Chem (2001) 0.86

Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase. J Biol Inorg Chem (2008) 0.85

Trypanosoma cruzi: molecular characterization of TcPUF6, a Pumilio protein. Exp Parasitol (2005) 0.85

Molecular characterization of the Trypanosoma cruzi specific RNA binding protein TcRBP40 and its associated mRNAs. Biochem Biophys Res Commun (2012) 0.85

The bacterium endosymbiont of Crithidia deanei undergoes coordinated division with the host cell nucleus. PLoS One (2010) 0.85

Myosin-Va mediates RNA distribution in primary fibroblasts from multiple organs. Cell Motil Cytoskeleton (2008) 0.84

Trypanosoma cruzi: a stage-specific calpain-like protein is induced after various kinds of stress. Mem Inst Oswaldo Cruz (2008) 0.84

Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents. J Inorg Biochem (2007) 0.84

'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase. Bioorg Med Chem (2010) 0.84

The pentose phosphate pathway in Trypanosoma cruzi: a potential target for the chemotherapy of Chagas disease. An Acad Bras Cienc (2007) 0.83

Human cardiac explant-conditioned medium: soluble factors and cardiomyogenic effect on mesenchymal stem cells. Exp Biol Med (Maywood) (2010) 0.83

Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica. PLoS Negl Trop Dis (2013) 0.83

Trypanosoma cruzi bromodomain factor 2 (BDF2) binds to acetylated histones and is accumulated after UV irradiation. Int J Parasitol (2008) 0.83

Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells. Biochem J (2013) 0.83

Active transcription and ultrastructural changes during Trypanosoma cruzi metacyclogenesis. An Acad Bras Cienc (2008) 0.82

Lytic activity and structural differences of amphipathic peptides derived from trialysin. Biochemistry (2006) 0.82

TcRRMs and Tcp28 genes are intercalated and differentially expressed in Trypanosoma cruzi life cycle. Biochem Biophys Res Commun (2004) 0.82

Comparative genomic analysis of dinucleotide repeats in Tritryps. Gene (2011) 0.81

Polysome profiling shows extensive posttranscriptional regulation during human adipocyte stem cell differentiation into adipocytes. Stem Cell Res (2013) 0.81

Expression of cardiac function genes in adult stem cells is increased by treatment with nitric oxide agents. Biochem Biophys Res Commun (2008) 0.81

A novel association between two trypanosome-specific factors and the conserved L5-5S rRNA complex. PLoS One (2012) 0.81

Nuclear structure of Trypanosoma cruzi. Adv Parasitol (2011) 0.81

DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Mol Biochem Parasitol (2012) 0.81

New achievements on biological aspects of copper complexes Casiopeínas®: interaction with DNA and proteins and anti-Trypanosoma cruzi activity. J Inorg Biochem (2012) 0.80

Distinct acetylation of Trypanosoma cruzi histone H4 during cell cycle, parasite differentiation, and after DNA damage. Chromosoma (2009) 0.80

Identification, cloning and characterization of an aldo-keto reductase from Trypanosoma cruzi with quinone oxido-reductase activity. Mol Biochem Parasitol (2010) 0.80

The zinc finger protein TcZFP2 binds target mRNAs enriched during Trypanosoma cruzi metacyclogenesis. Mem Inst Oswaldo Cruz (2012) 0.80

In vitro formation of capillary tubules from human umbilical cord blood cells with perspectives for therapeutic application. Rev Bras Cir Cardiovasc (2009) 0.80

Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase. Bioorg Med Chem (2011) 0.80

A novel type of single-stranded nucleic acid binding protein recognizing a highly frequent motif in the intergenic regions of Trypanosoma cruzi. Biochem Biophys Res Commun (2003) 0.80

Histone H1 is phosphorylated in non-replicating and infective forms of Trypanosoma cruzi. Mol Biochem Parasitol (2002) 0.80

PUMILIO-2 is involved in the positive regulation of cellular proliferation in human adipose-derived stem cells. Stem Cells Dev (2011) 0.80

Three-dimensional reconstruction of Trypanosoma cruzi epimastigotes and organelle distribution along the cell division cycle. Cytometry A (2011) 0.79

Association of a novel preribosomal complex in Trypanosoma brucei determined by fluorescence resonance energy transfer. Eukaryot Cell (2012) 0.79

Secreted trypanosome cyclophilin inactivates lytic insect defense peptides and induces parasite calcineurin activation and infectivity. J Biol Chem (2013) 0.79

A novel vanadyl complex with a polypyridyl DNA intercalator as ligand: a potential anti-protozoa and anti-tumor agent. J Inorg Biochem (2009) 0.79

Three distinct isoforms of ATP synthase subunit c are expressed in T. brucei and assembled into the mitochondrial ATP synthase complex. PLoS One (2013) 0.79

Differential expression profiles in the midgut of Triatoma infestans infected with Trypanosoma cruzi. PLoS One (2013) 0.79

Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity. Int J Biochem Cell Biol (2010) 0.79

Role of alternative polyadenylation during adipogenic differentiation: an in silico approach. PLoS One (2013) 0.79

Biochemical characterization of a protein tyrosine phosphatase from Trypanosoma cruzi involved in metacyclogenesis and cell invasion. Biochem Biophys Res Commun (2011) 0.79

Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery. Nucleus (2011) 0.79

Defining the RNA-protein interactions in the trypanosome preribosomal complex. Eukaryot Cell (2013) 0.79

Myosin-Va-dependent cell-to-cell transfer of RNA from Schwann cells to axons. PLoS One (2013) 0.79

The overexpression of the trypanosomatid-exclusive TcRBP19 RNA-binding protein affects cellular infection by Trypanosoma cruzi. Mem Inst Oswaldo Cruz (2012) 0.78

Characterization of anti-silencing factor 1 in Leishmania major. Mem Inst Oswaldo Cruz (2012) 0.78

Ribosome biogenesis requires a highly diverged XRN family 5'->3' exoribonuclease for rRNA processing in Trypanosoma brucei. RNA (2013) 0.78

A novel monoclonal antibody against the C-terminus of β-tubulin recognizes endocytic organelles in Trypanosoma cruzi. Protein Pept Lett (2012) 0.78

mRNA localization mechanisms in Trypanosoma cruzi. PLoS One (2013) 0.78

The malate dehydrogenase isoforms from Trypanosoma brucei: subcellular localization and differential expression in bloodstream and procyclic forms. Int J Parasitol (2005) 0.78

Divalent metal requirements for catalysis and stability of the RNA triphosphatase from Trypanosoma cruzi. Mol Biochem Parasitol (2006) 0.78

DNA conformational changes and cleavage by ruthenium(II) nitrofurylsemicarbazone complexes. J Inorg Biochem (2006) 0.78