Published in Cytokine Growth Factor Rev on February 01, 2003
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc Natl Acad Sci U S A (2007) 1.83
Semaphorins: a new class of immunoregulatory molecules. Philos Trans R Soc Lond B Biol Sci (2005) 0.96
Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Blood (2011) 0.91
CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection. PLoS One (2014) 0.75
Osteoprotection by semaphorin 3A. Nature (2012) 3.40
FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci (2005) 2.87
Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat Cell Biol (2006) 2.57
Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling. Nat Cell Biol (2004) 2.39
Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev (2004) 2.22
Neuromyelitis optica: Passive transfer to rats by human immunoglobulin. Biochem Biophys Res Commun (2009) 2.20
Semaphorins and their receptors in immune cell interactions. Nat Immunol (2007) 2.07
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature (2002) 2.04
The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. Immunity (2012) 1.98
Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature (2007) 1.87
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc Natl Acad Sci U S A (2007) 1.83
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest (2003) 1.80
RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis. Nat Med (2011) 1.71
Dynamic visualization of RANKL and Th17-mediated osteoclast function. J Clin Invest (2013) 1.68
Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. J Clin Invest (2002) 1.67
Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med (2008) 1.63
Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. J Immunol (2002) 1.55
Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity. Am J Respir Crit Care Med (2012) 1.55
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages. J Exp Med (2008) 1.53
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J Neurosci (2003) 1.46
Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells. Biochem Biophys Res Commun (2010) 1.40
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice. Immunity (2005) 1.39
Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Dev Biol (2008) 1.36
Structural basis for semaphorin signalling through the plexin receptor. Nature (2010) 1.33
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol (2010) 1.33
Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells. J Immunol (2002) 1.33
Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1. EMBO J (2007) 1.28
Semaphorins in interactions between T cells and antigen-presenting cells. Nat Rev Immunol (2003) 1.28
A midline switch of receptor processing regulates commissural axon guidance in vertebrates. Genes Dev (2010) 1.25
Immune semaphorins: a new area of semaphorin research. J Cell Sci (2003) 1.25
Bimodal regulation of T cell-mediated immune responses by TIM-4. Int Immunol (2008) 1.23
Early [18F]fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung. Clin Cancer Res (2011) 1.22
Diverse roles for semaphorin-plexin signaling in the immune system. Trends Immunol (2012) 1.20
Astrocytic necrosis is induced by anti-aquaporin-4 antibody-positive serum. Neuroreport (2009) 1.19
Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12. Proc Natl Acad Sci U S A (2009) 1.15
Roles of Sema4D and Plexin-B1 in tumor progression. Mol Cancer (2010) 1.13
Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron (2012) 1.08
Regulation of immune cell responses by semaphorins and their receptors. Cell Mol Immunol (2010) 1.08
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses. Int Immunol (2003) 1.07
Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones. Int Immunol (2002) 1.06
Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci U S A (2009) 1.05
Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. Blood (2010) 1.05
Immune semaphorins: novel features of neural guidance molecules. J Clin Immunol (2008) 1.04
Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin. J Immunol (2011) 1.02
Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.02
Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development. Dev Biol (2008) 1.01
Plexin-A4 negatively regulates T lymphocyte responses. Int Immunol (2008) 1.01
Control of bone resorption by semaphorin 4D is dependent on ovarian function. PLoS One (2011) 1.01
Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med (2012) 1.00
Immunological functions of the neuropilins and plexins as receptors for semaphorins. Nat Rev Immunol (2013) 1.00
Inhibitory roles of signal transducer and activator of transcription 3 in antitumor immunity during carcinogen-induced lung tumorigenesis. Cancer Res (2012) 0.99
Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 0.98
CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. Int Immunol (2007) 0.98
Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells. J Immunol (2010) 0.97
A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab. Mod Rheumatol (2011) 0.96
Semaphorins: a new class of immunoregulatory molecules. Philos Trans R Soc Lond B Biol Sci (2005) 0.96
Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation. Development (2011) 0.96
Wilms tumor gene (WT1) peptide-based cancer vaccine combined with gemcitabine for patients with advanced pancreatic cancer. J Immunother (2014) 0.95
Involvement of STAT3 in immune evasion during lung tumorigenesis. Oncoimmunology (2013) 0.94
CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis. J Immunol (2006) 0.93
Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis. J Neuroinflammation (2011) 0.92
Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals. Int Immunol (2002) 0.91
Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Mol Cell Neurosci (2010) 0.91
Development of microscopic polyangiitis-related pulmonary fibrosis in a patient with autoimmune pulmonary alveolar proteinosis. BMC Pulm Med (2014) 0.90
Semaphorins in bone development, homeostasis, and disease. Semin Cell Dev Biol (2012) 0.90
Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements. FASEB J (2010) 0.90
Roles of the semaphorin family in immune regulation. Adv Immunol (2003) 0.90
Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol (2005) 0.89
Tocilizumab for the treatment of patients with refractory Takayasu arteritis. Int Heart J (2013) 0.89
Elevation of Sema4A implicates Th cell skewing and the efficacy of IFN-β therapy in multiple sclerosis. J Immunol (2012) 0.89
Neuropilin-1: the glue between regulatory T cells and dendritic cells? Immunity (2008) 0.89
Immune semaphorins: increasing members and their diverse roles. Adv Immunol (2007) 0.89
The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses. J Exp Med (2011) 0.88
Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int J Mol Med (2010) 0.88