Published in J Cell Sci on September 01, 2003
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol Rev (2010) 2.64
TIM-1, a novel allergy and asthma susceptibility gene. Springer Semin Immunopathol (2003) 1.72
Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1. J Biol Chem (2009) 1.28
Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease. Arthritis Rheum (2011) 1.14
Semaphorin 3A is a new early diagnostic biomarker of experimental and pediatric acute kidney injury. PLoS One (2013) 1.10
Identification of novel mutations in the SEMA4A gene associated with retinal degenerative diseases. J Med Genet (2005) 1.08
Biology and function of neuroimmune semaphorins 4A and 4D. Immunol Res (2011) 1.03
Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc. Arthritis Res Ther (2010) 0.97
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance. Proc Natl Acad Sci U S A (2006) 0.95
Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons. J Biol Chem (2010) 0.93
Neuroimmune semaphorin 4A downregulates the severity of allergic response. Mucosal Immunol (2012) 0.92
The signaling adaptor protein CD3zeta is a negative regulator of dendrite development in young neurons. Mol Biol Cell (2008) 0.92
Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol (2014) 0.91
Expression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factor. BMC Immunol (2011) 0.90
The class 6 semaphorin SEMA6A is induced by interferon-gamma and defines an activation status of langerhans cells observed in pathological situations. Am J Pathol (2006) 0.89
Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications. Arthritis Rheumatol (2015) 0.86
Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice. J Mol Med (Berl) (2014) 0.85
Identification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in platelets. Blood (2013) 0.82
A novel role for the semaphorin Sema4D in the induction of allo-responses. Biol Blood Marrow Transplant (2007) 0.82
Repulsive guidance cue semaphorin 3A in urine predicts the progression of acute kidney injury in adult patients from a mixed intensive care unit. Nephrol Dial Transplant (2013) 0.80
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells. J Immunol (2016) 0.80
Neuroimmune semaphorin 4D is necessary for optimal lung allergic inflammation. Mol Immunol (2013) 0.77
CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72. PLoS One (2007) 0.77
Semaphorin 7A as a potential immune regulator and promising therapeutic target in rheumatoid arthritis. Arthritis Res Ther (2017) 0.77
Modulation of gene expression in CD4+ T lymphocytes following in vitro HIV infection: a comparison between human and chimpanzee. Virusdisease (2015) 0.75
Neuropilin-1 in transplantation tolerance. Front Immunol (2013) 0.75
FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci (2005) 2.87
Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis. Nat Cell Biol (2006) 2.57
Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling. Nat Cell Biol (2004) 2.39
Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev (2004) 2.22
Semaphorins and their receptors in immune cell interactions. Nat Immunol (2007) 2.07
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature (2002) 2.04
The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. Immunity (2012) 1.98
Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature (2007) 1.87
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc Natl Acad Sci U S A (2007) 1.83
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. J Clin Invest (2003) 1.80
Short-circuiting long-lived humoral immunity by the heightened engagement of CD40. J Clin Invest (2002) 1.67
Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med (2008) 1.63
Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. J Immunol (2002) 1.55
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages. J Exp Med (2008) 1.53
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion. J Neurosci (2003) 1.46
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice. Immunity (2005) 1.39
Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Dev Biol (2008) 1.36
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol (2010) 1.33
Requirement for the lymphocyte semaphorin, CD100, in the induction of antigen-specific T cells and the maturation of dendritic cells. J Immunol (2002) 1.33
Bimodal regulation of T cell-mediated immune responses by TIM-4. Int Immunol (2008) 1.23
Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses. Int Immunol (2003) 1.07
Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones. Int Immunol (2002) 1.06
Enhanced humoral immune responses against T-independent antigens in Fc alpha/muR-deficient mice. Proc Natl Acad Sci U S A (2009) 1.05
Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. Blood (2010) 1.05
Immune semaphorins: novel features of neural guidance molecules. J Clin Immunol (2008) 1.04
Roles of Sema4D-plexin-B1 interactions in the central nervous system for pathogenesis of experimental autoimmune encephalomyelitis. J Immunol (2009) 1.02
Plexin-A4 negatively regulates T lymphocyte responses. Int Immunol (2008) 1.01
Control of bone resorption by semaphorin 4D is dependent on ovarian function. PLoS One (2011) 1.01
Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor. J Exp Med (2012) 1.00
Immunological functions of the neuropilins and plexins as receptors for semaphorins. Nat Rev Immunol (2013) 1.00
Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 0.98
Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells. J Immunol (2010) 0.97
Semaphorins: a new class of immunoregulatory molecules. Philos Trans R Soc Lond B Biol Sci (2005) 0.96
CD100 enhances dendritic cell and CD4+ cell activation leading to pathogenetic humoral responses and immune complex glomerulonephritis. J Immunol (2006) 0.93
Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis. J Neuroinflammation (2011) 0.92
Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Mol Cell Neurosci (2010) 0.91
Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals. Int Immunol (2002) 0.91
Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements. FASEB J (2010) 0.90
Roles of the semaphorin family in immune regulation. Adv Immunol (2003) 0.90
Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol (2005) 0.89
Neuropilin-1: the glue between regulatory T cells and dendritic cells? Immunity (2008) 0.89
The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses. J Exp Med (2011) 0.88
An inhibitory role for Sema4A in antigen-specific allergic asthma. J Clin Immunol (2012) 0.88
Deletion of Sema4D gene reduces intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Int J Mol Med (2010) 0.88
Sema4A induces cell morphological changes through B-type plexin-mediated signaling. Int J Mol Med (2010) 0.87
Endogenous CD100 promotes glomerular injury and macrophage recruitment in experimental crescentic glomerulonephritis. Immunology (2009) 0.86
Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation. Proc Natl Acad Sci U S A (2012) 0.85
Semaphorin signaling during cardiac development. Adv Exp Med Biol (2007) 0.84
Semaphorins and their receptors: novel features of neural guidance molecules. Proc Jpn Acad Ser B Phys Biol Sci (2010) 0.84
BAFF controls neural cell survival through BAFF receptor. PLoS One (2013) 0.83
Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior. Can J Neurol Sci (2009) 0.82
Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity. J Biol Chem (2013) 0.82
Induction of cyclooxygenase-2 in reactive glial cells by the CD40 pathway: relevance to amyotrophic lateral sclerosis. J Neurochem (2004) 0.82
Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation. Hepatology (2007) 0.82
Peptide analysis, stability studies, and structural modeling explain contradictory peptide motifs and unique properties of the NOD mouse MHC class II molecule H2-A(g7). Eur J Immunol (2002) 0.82
CD100/Sema4D, a lymphocyte semaphorin involved in the regulation of humoral and cellular immune responses. Cytokine Growth Factor Rev (2003) 0.82
Involvement of Sema4A in the progression of experimental autoimmune myocarditis. FEBS Lett (2008) 0.81
Semaphorin 4A induces growth cone collapse of hippocampal neurons in a Rho/Rho-kinase-dependent manner. Int J Mol Med (2005) 0.81
Loss of dopaminergic neurons by the induction of inducible nitric oxide synthase and cyclooxygenase-2 via CD 40: relevance to Parkinson's disease. J Neurosci Res (2005) 0.80
Partial suppression of M1 microglia by Janus kinase 2 inhibitor does not protect against neurodegeneration in animal models of amyotrophic lateral sclerosis. J Neuroinflammation (2014) 0.77