Published in Angew Chem Int Ed Engl on February 01, 2002
Novel Cyclopropyl-Indole Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors. ACS Med Chem Lett (2012) 1.52
Chemical synthesis of proteins using peptide hydrazides as thioester surrogates. Nat Protoc (2013) 1.09
Rapid total synthesis of DARPin pE59 and barnase. Chembiochem (2014) 0.89
Dicyclopropylmethyl peptide backbone protectant. Org Lett (2009) 0.78
Facile synthesis of 1-alkoxy-1H-benzo- and 7-azabenzotriazoles from peptide coupling agents, mechanistic studies, and synthetic applications. Beilstein J Org Chem (2014) 0.78
Functionalized analogues of an unnatural amino acid that mimics a tripeptide beta-strand. Org Lett (2008) 0.76
Synergism and mutualism in non-enzymatic RNA polymerization. Life (Basel) (2014) 0.75
Total chemical synthesis of histones and their analogs, assisted by native chemical ligation and palladium complexes. Nat Protoc (2017) 0.75
Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis. Nature (2006) 5.52
High-throughput generation of selected reaction-monitoring assays for proteins and proteomes. Nat Methods (2009) 4.17
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc Natl Acad Sci U S A (2007) 2.97
An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope. Nat Immunol (2003) 2.38
SIRT1 regulates HIV transcription via Tat deacetylation. PLoS Biol (2005) 2.24
The signal flow and motor response controling chemotaxis of sea urchin sperm. Nat Cell Biol (2003) 2.24
Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk of infection in the RV144 vaccine efficacy trial. PLoS One (2013) 1.94
Sequence requirements and an optimization strategy for short antimicrobial peptides. Chem Biol (2006) 1.84
Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR. Cell (2013) 1.83
Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences. Nat Protoc (2007) 1.73
Hepatitis C virus mutation affects proteasomal epitope processing. J Clin Invest (2004) 1.58
Pd-catalyzed stereoselective oxidation of methyl groups by inexpensive oxidants under mild conditions: a dual role for carboxylic anhydrides in catalytic C--H bond oxidation. Angew Chem Int Ed Engl (2005) 1.56
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. EMBO J (2003) 1.53
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells. J Am Soc Nephrol (2006) 1.50
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J (2002) 1.49
An unlocking/relocking barrier in conformational fluctuations of villin headpiece subdomain. Proc Natl Acad Sci U S A (2010) 1.47
Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A (2010) 1.47
WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains. Protein Sci (2003) 1.46
Oxyma: an efficient additive for peptide synthesis to replace the benzotriazole-based HOBt and HOAt with a lower risk of explosion. Chemistry (2009) 1.45
Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation. Mol Cell (2003) 1.42
Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells. J Biol Chem (2004) 1.39
Stereocontrolled creation of adjacent quaternary and tertiary stereocenters by a catalytic conjugate addition. Angew Chem Int Ed Engl (2004) 1.39
Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation. J Virol (2005) 1.37
Antibody to AP1B adaptor blocks biosynthetic and recycling routes of basolateral proteins at recycling endosomes. Mol Biol Cell (2007) 1.35
Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci (2009) 1.34
Synthesis of biologically active peptide nucleic acid-peptide conjugates by sortase-mediated ligation. J Org Chem (2007) 1.32
Cyclization increases the antimicrobial activity and selectivity of arginine- and tryptophan-containing hexapeptides. Biochemistry (2004) 1.31
A Toll-like receptor 2-integrin beta3 complex senses bacterial lipopeptides via vitronectin. Nat Immunol (2008) 1.29
Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J Biol Chem (2008) 1.29
Coordination chemistry of H2 and N2 in aqueous solution. Reactivity and mechanistic studies using trans-FeII(P2)2X2)-type complexes (P2 = a chelating, water-solubilizing phosphine). Inorg Chem (2007) 1.28
G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta. J Biol Chem (2008) 1.28
Ligand-dependent differences in the internalization of endothelin A and endothelin B receptor heterodimers. J Biol Chem (2004) 1.26
Ca2+ spikes in the flagellum control chemotactic behavior of sperm. EMBO J (2005) 1.25
Characterization of humoral and cellular immune responses elicited by a recombinant adenovirus serotype 26 HIV-1 Env vaccine in healthy adults (IPCAVD 001). J Infect Dis (2012) 1.21
Wavelength-selective photoactivatable protecting groups for thiols. J Am Chem Soc (2009) 1.15
Sequence of interactions in receptor-G protein coupling. J Biol Chem (2004) 1.15
Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling. J Biol Chem (2006) 1.14
HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis. Virology (2002) 1.14
Structural characterization and oligomerization of PB1-F2, a proapoptotic influenza A virus protein. J Biol Chem (2006) 1.12
Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum. Antimicrob Agents Chemother (2008) 1.12
The corticotropin-releasing factor receptor type 2a contains an N-terminal pseudo signal peptide. J Biol Chem (2006) 1.11
Mass-spectrometric identification of a novel angiotensin peptide in human plasma. Arterioscler Thromb Vasc Biol (2006) 1.10
Regulation of the coupling to different G proteins of rat corticotropin-releasing factor receptor type 1 in human embryonic kidney 293 cells. J Biol Chem (2004) 1.09
Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes. Cell Microbiol (2009) 1.08
Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. J Biol Chem (2003) 1.05
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides. Biochem J (2006) 1.04
Ca(2+) sensor S100beta-modulated sites of membrane guanylate cyclase in the photoreceptor-bipolar synapse. EMBO J (2002) 1.04
Solution structure of the human immunodeficiency virus type 1 p6 protein. J Biol Chem (2005) 1.04
Formal synthesis of (+/-)-platensimycin. Org Lett (2007) 1.03
General aspects of peptide selectivity towards lipid bilayers and cell membranes studied by variation of the structural parameters of amphipathic helical model peptides. Biochim Biophys Acta (2002) 1.03
Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent. Neurosci Lett (2003) 1.02
Structural requirements for cellular uptake and antisense activity of peptide nucleic acids conjugated with various peptides. Biochemistry (2006) 1.02
Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand binding. J Recept Signal Transduct Res (2005) 1.02
MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. J Biol Chem (2009) 1.02
The signal peptide of the rat corticotropin-releasing factor receptor 1 promotes receptor expression but is not essential for establishing a functional receptor. Biochem J (2005) 1.02
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins. J Phys Chem B (2007) 1.02
Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation. Novartis Found Symp (2004) 1.01
The extracellular N terminus of the endothelin B (ETB) receptor is cleaved by a metalloprotease in an agonist-dependent process. J Biol Chem (2002) 1.01
An apolipoprotein E-derived peptide mediates uptake of sterically stabilized liposomes into brain capillary endothelial cells. Biochemistry (2005) 0.99
Antibody signatures defined by high-content peptide microarray analysis. Methods Mol Biol (2010) 0.99
Uptake of cell-penetrating peptides is dependent on peptide-to-cell ratio rather than on peptide concentration. Biochim Biophys Acta (2004) 0.98
Screening and characterization of surface-tethered cationic peptides for antimicrobial activity. Chem Biol (2009) 0.98
The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes. J Pept Sci (2008) 0.98
PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nat Commun (2011) 0.97
A critical reassessment of penetratin translocation across lipid membranes. Biophys J (2005) 0.96
The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel. PLoS One (2010) 0.96
The RTP site shared by the HIV-1 Tat protein and the 11S regulator subunit alpha is crucial for their effects on proteasome function including antigen processing. J Mol Biol (2002) 0.96
Helix formation in arrestin accompanies recognition of photoactivated rhodopsin. Biochemistry (2009) 0.96
Thermodynamics of the coil-alpha-helix transition of amphipathic peptides in a membrane environment: the role of vesicle curvature. Biophys Chem (2002) 0.95
Membrane-mimetic nanocarriers formed by a dipalmitoylated cell-penetrating peptide. Angew Chem Int Ed Engl (2005) 0.95
Solution structure and function of the "tandem inactivation domain" of the neuronal A-type potassium channel Kv1.4. J Biol Chem (2003) 0.95
Structural characterization of the HIV-1 Vpr N terminus: evidence of cis/trans-proline isomerism. J Biol Chem (2003) 0.94
Organophosphorus and nitro-substituted sulfonate esters of 1-hydroxy-7-azabenzotriazole as highly efficient fast-acting peptide coupling reagents. J Org Chem (2004) 0.94
The contributions of specific amino acid side chains to signal intensities of peptides in matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom (2004) 0.94
Asymmetric Diels-Alder reactions of 2-pyrones with a bifunctional organic catalyst. J Am Chem Soc (2007) 0.94
Activation of CO2 by a heterobimetallic Zr/Co complex. J Am Chem Soc (2011) 0.93
Mode of action of cationic antimicrobial peptides defines the tethering position and the efficacy of biocidal surfaces. Bioconjug Chem (2011) 0.93
Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion. Carcinogenesis (2009) 0.92
Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues. Biochemistry (2005) 0.92
PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res (2004) 0.92
Human B1 and B2 bradykinin receptors and their agonists target caveolae-related lipid rafts to different degrees in HEK293 cells. Biochemistry (2002) 0.92
Antitopes define preferential proteasomal cleavage site usage. J Biol Chem (2008) 0.92
A xenon-129 biosensor for monitoring MHC-peptide interactions. Angew Chem Int Ed Engl (2009) 0.91
Peptide impurities in commercial synthetic peptides and their implications for vaccine trial assessment. Clin Vaccine Immunol (2007) 0.91
Temporal sampling, resetting, and adaptation orchestrate gradient sensing in sperm. J Cell Biol (2012) 0.91
Synthesis of protein mimics with nonlinear backbone topology by a combined recombinant, enzymatic, and chemical synthesis strategy. Angew Chem Int Ed Engl (2008) 0.91
Cyclization of all-L-Pentapeptides by Means of 1-Hydroxy-7-azabenzotriazole-Derived Uronium and Phosphonium Reagents. J Org Chem (1996) 0.91
Group 10 and 11 metal boratranes (Ni, Pd, Pt, CuCl, AgCl, AuCl, and Au+) derived from a triphosphine-borane. J Am Chem Soc (2008) 0.91