Published in Nucleic Acids Res on January 15, 2003
Post-transcriptional nucleotide modification and alternative folding of RNA. Nucleic Acids Res (2006) 2.34
Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease. Proc Natl Acad Sci U S A (2005) 1.50
Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease. Proc Natl Acad Sci U S A (2004) 1.47
Mitochondrial tRNA 3' end metabolism and human disease. Nucleic Acids Res (2004) 1.37
Unique features of animal mitochondrial translation systems. The non-universal genetic code, unusual features of the translational apparatus and their relevance to human mitochondrial diseases. Proc Jpn Acad Ser B Phys Biol Sci (2010) 1.14
Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants. RNA (2004) 0.88
Structural probing of a pathogenic tRNA dimer. RNA (2005) 0.88
A disease-causing point mutation in human mitochondrial tRNAMet rsults in tRNA misfolding leading to defects in translational initiation and elongation. J Biol Chem (2008) 0.87
A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations. Nucleic Acids Res (2005) 0.82
Tertiary network in mammalian mitochondrial tRNAAsp revealed by solution probing and phylogeny. Nucleic Acids Res (2009) 0.81
Pathology-related mutation A7526G (A9G) helps in the understanding of the 3D structural core of human mitochondrial tRNA(Asp). RNA (2009) 0.76
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
Direct chemical method for sequencing RNA. Proc Natl Acad Sci U S A (1979) 25.15
Compilation of tRNA sequences and sequences of tRNA genes. Nucleic Acids Res (1998) 10.74
Chemical probes for higher-order structure in RNA. Proc Natl Acad Sci U S A (1980) 5.38
The mitochondrial genome: structure, transcription, translation and replication. Biochim Biophys Acta (1999) 4.40
Search for characteristic structural features of mammalian mitochondrial tRNAs. RNA (2000) 2.84
The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA. Nucleic Acids Res (1998) 1.92
Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease. EMBO J (2001) 1.77
Molecular recognition of the identity-determinant set of isoleucine transfer RNA from Escherichia coli. J Mol Biol (1994) 1.68
Modification defect at anticodon wobble nucleotide of mitochondrial tRNAs(Leu)(UUR) with pathogenic mutations of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. J Biol Chem (2000) 1.57
Screening of patients with maternally transmitted diabetes for mitochondrial gene mutations in the tRNA[Leu(UUR)] region. Diabet Med (1997) 1.46
A new mtDNA mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Biochim Biophys Acta (1991) 1.46
Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR). Nucleic Acids Res (1999) 1.26
Dimerization of a pathogenic human mitochondrial tRNA. Nat Struct Biol (2002) 1.17
Impairment of tRNA processing by point mutations in mitochondrial tRNA(Leu)(UUR) associated with mitochondrial diseases. FEBS Lett (1998) 1.16
Identification of essential domains for Escherichia coli tRNA(leu) aminoacylation and amino acid editing using minimalist RNA molecules. Nucleic Acids Res (2002) 1.16
RNA binding determinant in some class I tRNA synthetases identified by alignment-guided mutagenesis. Proc Natl Acad Sci U S A (1992) 1.04
Expression and characterization of the human mitochondrial leucyl-tRNA synthetase. Biochim Biophys Acta (2000) 1.03
Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility. Nat Struct Biol (2000) 1.01
Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene. Hum Mol Genet (1998) 0.98
Fragile T-stem in disease-associated human mitochondrial tRNA sensitizes structure to local and distant mutations. J Biol Chem (2000) 0.97
A pathogenic point mutation reduces stability of mitochondrial mutant tRNA(Ile). Nucleic Acids Res (2000) 0.96
In vitro 3'-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness. Nucleic Acids Res (2001) 0.94
RNA determinants for translational editing. Mischarging a minihelix substrate by a tRNA synthetase. J Biol Chem (1999) 0.88
An ultrasensitive universal detector based on neutralizer displacement. Nat Chem (2012) 2.29
Recent advances in the use of cell-penetrating peptides for medical and biological applications. Adv Drug Deliv Rev (2009) 2.18
Cell-penetrating peptides as delivery vehicles for biology and medicine. Org Biomol Chem (2008) 1.79
Deconvolution of the cellular oxidative stress response with organelle-specific Peptide conjugates. Chem Biol (2007) 1.54
DNA-based programming of quantum dot valency, self-assembly and luminescence. Nat Nanotechnol (2011) 1.52
A general phase-transfer protocol for metal ions and its application in nanocrystal synthesis. Nat Mater (2009) 1.45
An aminoacyl-tRNA synthetase with a defunct editing site. Biochemistry (2005) 1.45
Impact of disease-related mitochondrial mutations on tRNA structure and function. Trends Biochem Sci (2003) 1.33
Programming the detection limits of biosensors through controlled nanostructuring. Nat Nanotechnol (2009) 1.32
Mitochondria-penetrating peptides. Chem Biol (2008) 1.32
Targeting mitochondria with organelle-specific compounds: strategies and applications. Chembiochem (2009) 1.26
Direct profiling of cancer biomarkers in tumor tissue using a multiplexed nanostructured microelectrode integrated circuit. ACS Nano (2009) 1.19
Dimerization of a pathogenic human mitochondrial tRNA. Nat Struct Biol (2002) 1.17
NIR-emitting colloidal quantum dots having 26% luminescence quantum yield in buffer solution. J Am Chem Soc (2007) 1.13
Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers. Anal Chem (2003) 1.10
Protein detection using arrayed microsensor chips: tuning sensor footprint to achieve ultrasensitive readout of CA-125 in serum and whole blood. Anal Chem (2011) 1.02
One-step DNA-programmed growth of luminescent and biofunctionalized nanocrystals. Nat Nanotechnol (2008) 1.02
Direct, electronic microRNA detection for the rapid determination of differential expression profiles. Angew Chem Int Ed Engl (2009) 1.00
Direct electrocatalytic mRNA detection using PNA-nanowire sensors. Anal Chem (2009) 1.00
Amplified electrocatalysis at DNA-modified nanowires. Nano Lett (2005) 0.98
Polymerase chain reaction-free, sample-to-answer bacterial detection in 30 minutes with integrated cell lysis. Anal Chem (2011) 0.98
Solution-based circuits enable rapid and multiplexed pathogen detection. Nat Commun (2013) 0.97
Hierarchical nanotextured microelectrodes overcome the molecular transport barrier to achieve rapid, direct bacterial detection. ACS Nano (2011) 0.97
Targeting mitochondrial DNA with a platinum-based anticancer agent. Chem Biol (2013) 0.97
Targeted delivery of doxorubicin to mitochondria. ACS Chem Biol (2013) 0.96
Mitochondria-penetrating peptides: sequence effects and model cargo transport. Chembiochem (2009) 0.93
Nanostructuring of sensors determines the efficiency of biomolecular capture. Anal Chem (2010) 0.93
Comparison of the quality of aqueous dispersions of single wall carbon nanotubes using surfactants and biomolecules. Langmuir (2008) 0.93
Cellular uptake of substrate-initiated cell-penetrating poly(disulfide)s. J Am Chem Soc (2014) 0.92
DNA-passivated CdS nanocrystals: luminescence, bioimaging, and toxicity profiles. Langmuir (2007) 0.92
Molecular vehicles for mitochondrial chemical biology and drug delivery. ACS Chem Biol (2014) 0.91
Nanoparticle-mediated binning and profiling of heterogeneous circulating tumor cell subpopulations. Angew Chem Int Ed Engl (2014) 0.90
Thiazole orange-peptide conjugates: sensitivity of DNA binding to chemical structure. Org Lett (2004) 0.90
Ultrasensitive electrocatalytic DNA detection at two- and three-dimensional nanoelectrodes. J Am Chem Soc (2004) 0.90
Direct genetic analysis of ten cancer cells: tuning sensor structure and molecular probe design for efficient mRNA capture. Angew Chem Int Ed Engl (2011) 0.90
Tuning the activity of mitochondria-penetrating peptides for delivery or disruption. Chembiochem (2012) 0.90
Nanostructuring of patterned microelectrodes to enhance the sensitivity of electrochemical nucleic acids detection. Angew Chem Int Ed Engl (2009) 0.90
Rapid and specific electrochemical detection of prostate cancer cells using an aperture sensor array. Lab Chip (2013) 0.89
Structural probing of a pathogenic tRNA dimer. RNA (2005) 0.88
Nucleotide-directed growth of semiconductor nanocrystals. J Am Chem Soc (2006) 0.87
Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells. Chem Biol (2011) 0.87
RNA-templated semiconductor nanocrystals. J Am Chem Soc (2006) 0.87
Nucleic acid-passivated semiconductor nanocrystals: biomolecular templating of form and function. Acc Chem Res (2010) 0.87
A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation. Biochemistry (2007) 0.86
Cyanine dye conjugates as probes for live cell imaging. Bioorg Med Chem Lett (2007) 0.85
The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells. Blood (2010) 0.85
Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells. J Am Chem Soc (2011) 0.84
Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism. PLoS One (2013) 0.83
Engineered apoptosis-inducing peptides with enhanced mitochondrial localization and potency. J Med Chem (2009) 0.83
Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol (2009) 0.82
Quantification of the binding affinity of a specific hydroxyapatite binding peptide. Biomaterials (2010) 0.82
Ultrasensitive detection of enzymatic activity with nanowire electrodes. J Am Chem Soc (2007) 0.82
Tuning the bacterial detection sensitivity of nanostructured microelectrodes. Anal Chem (2013) 0.81
Proximal bacterial lysis and detection in nanoliter wells using electrochemistry. ACS Nano (2013) 0.81
Oxidative DNA strand scission induced by peptides. Chem Biol (2005) 0.81
Electrochemical enzyme-linked immunosorbent assay featuring proximal reagent generation: detection of human immunodeficiency virus antibodies in clinical samples. Anal Chem (2013) 0.81
Interdomain communication between weak structural elements within a disease-related human tRNA. Biochemistry (2004) 0.80
Ultrasensitive electrochemical biomolecular detection using nanostructured microelectrodes. Acc Chem Res (2014) 0.80
Rapid electrochemical phenotypic profiling of antibiotic-resistant bacteria. Lab Chip (2015) 0.80
Nanostructured biomolecular detectors: pushing performance at the nanoscale. Curr Opin Chem Biol (2012) 0.79
Chip-based nanostructured sensors enable accurate identification and classification of circulating tumor cells in prostate cancer patient blood samples. Anal Chem (2012) 0.79
Tuning the intracellular bacterial targeting of peptidic vectors. Angew Chem Int Ed Engl (2013) 0.78
Three-dimensional, sharp-tipped electrodes concentrate applied fields to enable direct electrical release of intact biomarkers from cells. Lab Chip (2014) 0.78
Optimized templates for bottom-up growth of high-performance integrated biomolecular detectors. Lab Chip (2013) 0.78
A digital microfluidic device with integrated nanostructured microelectrodes for electrochemical immunoassays. Lab Chip (2015) 0.78
Effect of microelectrode structure on electrocatalysis at nucleic acid-modified sensors. Langmuir (2014) 0.77
Combinatorial analysis of loop nucleotides in human mitochondrial tRNALeu(UUR). Biochemistry (2005) 0.77
Site-specific assembly of DNA and appended cargo on arrayed carbon nanotubes. J Am Chem Soc (2004) 0.77
Phototoxicity of peptidoconjugates modulated by a single amino acid. Angew Chem Int Ed Engl (2005) 0.77
High-Density Nanosharp Microstructures Enable Efficient CO2 Electroreduction. Nano Lett (2016) 0.77
Velocity valleys enable efficient capture and spatial sorting of nanoparticle-bound cancer cells. Nanoscale (2015) 0.76
Highly specific electrochemical analysis of cancer cells using multi-nanoparticle labeling. Angew Chem Int Ed Engl (2014) 0.76
Photosensitized DNA cleavage promoted by amino acids. Chem Commun (Camb) (2003) 0.76
Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion. Mol Pharm (2014) 0.75
High-Curvature Nanostructuring Enhances Probe Display for Biomolecular Detection. Nano Lett (2017) 0.75
Isolation of Phenotypically-Distinct Cancer Cells Using Nanoparticle-Mediated Sorting. ACS Appl Mater Interfaces (2017) 0.75
DISEASE DETECTOR. Sci Am (2015) 0.75
Solvatochromic reagents for multicomponent reactions and their utility in the development of cell-permeable macrocyclic peptide vectors. Chemistry (2011) 0.75
Synthesis, characterization, and cellular uptake of DNA-binding rose bengal peptidoconjugates. Org Lett (2005) 0.75
Novel microfluidic approaches. Curr Opin Chem Biol (2012) 0.75
Challenges and Opportunities for Wearable Sensing Systems. ACS Sens (2022) 0.75
Tunable DNA cleavage by intercalating peptidoconjugates. Chembiochem (2006) 0.75
Measurement science: the engine of chemical biology. Curr Opin Chem Biol (2008) 0.75
DNA-directed synthesis of zinc oxide nanowires on carbon nanotube tips. Nanotechnology (2006) 0.75
An intercalator film as a DNA-electrode interface. Chem Commun (Camb) (2006) 0.75
An electrochemical immunosensor based on antibody-nanowire conjugates. Analyst (2009) 0.75
DNA-based programing of quantum dot properties. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2012) 0.75