Published in J Natl Cancer Inst on January 15, 2003
Primary prevention of colorectal cancer. Gastroenterology (2010) 3.20
HFE C282Y homozygotes are at increased risk of breast and colorectal cancer. Hepatology (2010) 1.76
Mendelian randomization: how it can--and cannot--help confirm causal relations between nutrition and cancer. Cancer Prev Res (Phila) (2009) 1.51
Research recruitment through US central cancer registries: balancing privacy and scientific issues. Am J Public Health (2006) 1.37
Diet and supplements and their impact on colorectal cancer. J Gastrointest Oncol (2013) 1.27
Modulation of iron transport proteins in human colorectal carcinogenesis. Gut (2006) 1.23
Molecular and clinical aspects of iron homeostasis: From anemia to hemochromatosis. Wien Klin Wochenschr (2006) 0.97
Epidemiology of colonic aberrant crypt foci: review and analysis of existing studies. Cancer Lett (2006) 0.95
Iron: an emerging factor in colorectal carcinogenesis. World J Gastroenterol (2010) 0.90
Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Prev Res (Phila) (2011) 0.90
Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine. Am J Physiol Gastrointest Liver Physiol (2010) 0.89
Circulating gastrin is increased in hemochromatosis. FEBS Lett (2006) 0.88
Intestinal iron homeostasis and colon tumorigenesis. Nutrients (2013) 0.88
Gastrins, iron homeostasis and colorectal cancer. Biochim Biophys Acta (2011) 0.86
HFE C282Y and H63D in adults with malignancies in a community medical oncology practice. BMC Cancer (2004) 0.85
Another important function for an old friend! The role of iron in colorectal carcinogenesis. Gut (2006) 0.83
Interrelationships between circulating gastrin and iron status in mice and humans. Am J Physiol Gastrointest Liver Physiol (2008) 0.82
Alterations in expression profile of iron-related genes in colorectal cancer. Mol Biol Rep (2013) 0.82
Hemochromatosis (HFE) gene mutations and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Carcinogenesis (2013) 0.81
HFE gene variants, iron, and lipids: a novel connection in Alzheimer's disease. Front Pharmacol (2014) 0.81
Human risk of diseases associated with red meat intake: Analysis of current theories and proposed role for metabolic incorporation of a non-human sialic acid. Mol Aspects Med (2016) 0.79
Ferric ions inhibit proteolytic processing of progastrin. Biochem Biophys Res Commun (2010) 0.78
The risk of new-onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants. J Cell Mol Med (2016) 0.77
Blood donation and colorectal cancer incidence and mortality in men. PLoS One (2012) 0.77
C282Y-HFE gene variant affects cholesterol metabolism in human neuroblastoma cells. PLoS One (2014) 0.76
Evidence for the Influence of the Iron Regulatory MHC Class I Molecule HFE on Tumor Progression in Experimental Models and Clinical Populations. Transl Oncogenomics (2014) 0.76
Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers (Basel) (2015) 0.75
Dietary iron, iron homeostatic gene polymorphisms and the risk of advanced colorectal adenoma and cancer. Carcinogenesis (2014) 0.75
Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget (2016) 0.75
Re: Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer. J Natl Cancer Inst (2003) 0.75
The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system. Immun Inflamm Dis (2017) 0.75
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med (2005) 15.46
A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med (2003) 9.18
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA (2007) 7.93
Burden of gastrointestinal disease in the United States: 2012 update. Gastroenterology (2012) 7.15
Understanding cancer treatment and outcomes: the Cancer Care Outcomes Research and Surveillance Consortium. J Clin Oncol (2004) 7.02
Colorectal cancer in patients under close colonoscopic surveillance. Gastroenterology (2005) 4.31
Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults. Gastroenterology (2008) 3.79
Effect of adjuvant chemotherapy on survival of patients with stage III colon cancer diagnosed after age 75 years. J Clin Oncol (2012) 3.63
Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trial. J Natl Cancer Inst (2003) 3.44
Clinical practice. Screening for colorectal cancer. N Engl J Med (2002) 3.43
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology (2006) 3.35
Cystic fibrosis population carrier screening: 2004 revision of American College of Medical Genetics mutation panel. Genet Med (2004) 3.32
Constipation and a low-fiber diet are not associated with diverticulosis. Clin Gastroenterol Hepatol (2013) 3.31
Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials. J Natl Cancer Inst (2009) 3.15
A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology (2011) 3.03
Variability in diagnostic criteria for eosinophilic esophagitis: a systematic review. Am J Gastroenterol (2007) 2.94
The burden of gastrointestinal and liver diseases, 2006. Am J Gastroenterol (2006) 2.93
A Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas. N Engl J Med (2015) 2.88
Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial. Lancet (2008) 2.83
Increased risk for non-melanoma skin cancer in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol (2010) 2.80
A population-based cohort study comparing laparoscopic cholecystectomy and open cholecystectomy. Am J Gastroenterol (2002) 2.75
Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas. Gut Microbes (2010) 2.70
Folic acid and risk of prostate cancer: results from a randomized clinical trial. J Natl Cancer Inst (2009) 2.64
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet (2011) 2.43
RNA expression analysis of formalin-fixed paraffin-embedded tumors. Lab Invest (2007) 2.25
Development of an internet-based cohort of patients with inflammatory bowel diseases (CCFA Partners): methodology and initial results. Inflamm Bowel Dis (2012) 2.23
KRAS/BRAF mutation status and ERK1/2 activation as biomarkers for MEK1/2 inhibitor therapy in colorectal cancer. Mol Cancer Ther (2009) 2.22
Estrogen-plus-progestin use and mammographic density in postmenopausal women: Women's Health Initiative randomized trial. J Natl Cancer Inst (2005) 2.16
Digestive and liver diseases statistics, 2004. Gastroenterology (2004) 2.14
A causal association between isotretinoin and inflammatory bowel disease has yet to be established. Am J Gastroenterol (2009) 2.14
Circulating levels of inflammatory cytokines and risk of colorectal adenomas. Cancer Res (2008) 2.13
Isotretinoin use and the risk of inflammatory bowel disease: a case-control study. Am J Gastroenterol (2010) 2.10
Associations of total energy and macronutrients with colon cancer risk in African Americans and Whites: results from the North Carolina colon cancer study. Am J Epidemiol (2003) 2.06
Fusobacterium is associated with colorectal adenomas. PLoS One (2013) 1.99
Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. Gastroenterology (2012) 1.97
Pan-ethnic carrier screening and prenatal diagnosis for spinal muscular atrophy: clinical laboratory analysis of >72,400 specimens. Eur J Hum Genet (2011) 1.88
Genetic modifiers of liver disease in cystic fibrosis. JAMA (2009) 1.88
Sleep disturbance and risk of active disease in patients with Crohn's disease and ulcerative colitis. Clin Gastroenterol Hepatol (2013) 1.83
Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone. Am J Physiol Heart Circ Physiol (2007) 1.81
Patient time requirements for screening colonoscopy. Am J Gastroenterol (2007) 1.74
Patient and graft survival in hepatitis C recipients after adult living donor liver transplantation in the United States. Liver Transpl (2004) 1.74
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial. J Natl Cancer Inst (2007) 1.73
Editorial: colonoscopy and colorectal cancer mortality: strong beliefs or strong facts? Am J Gastroenterol (2010) 1.71
Characteristics and survival of interval and sporadic colorectal cancer patients: a nationwide population-based cohort study. Am J Gastroenterol (2013) 1.71
Suboptimal rates of cervical testing among women with inflammatory bowel disease. Clin Gastroenterol Hepatol (2008) 1.71
Thromboembolic risk among Danish children and adults with inflammatory bowel diseases: a population-based nationwide study. Gut (2011) 1.70
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology (2003) 1.70
Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers. Gastroenterology (2004) 1.70
Determinants of medical system delay in the diagnosis of colorectal cancer within the Veteran Affairs Health System. Dig Dis Sci (2010) 1.68
Effect of calcium supplementation on the risk of large bowel polyps. J Natl Cancer Inst (2004) 1.67
Forskolin stimulates phosphorylation and membrane accumulation of UT-A3. Am J Physiol Renal Physiol (2007) 1.66
Reduced polyp detection as endoscopy shift progresses: experience with screening colonoscopy at a tertiary-care hospital. J Clin Gastroenterol (2011) 1.66
Serum citrulline levels correlate with enteral tolerance and bowel length in infants with short bowel syndrome. J Pediatr (2005) 1.63
Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans. ISME J (2012) 1.62
Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts. J Am Soc Nephrol (2006) 1.60
Insulin resistance, apoptosis, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev (2005) 1.52
Donor morbidity associated with right lobectomy for living donor liver transplantation to adult recipients: a systematic review. Liver Transpl (2002) 1.52
The I148T CFTR allele occurs on multiple haplotypes: a complex allele is associated with cystic fibrosis. Genet Med (2002) 1.49
Recognition and treatment of irritable bowel syndrome among women with chronic pelvic pain. Am J Obstet Gynecol (2005) 1.49
Risk factors for advanced colorectal adenomas: a pooled analysis. Cancer Epidemiol Biomarkers Prev (2002) 1.48
Relationship of EMAST and microsatellite instability among patients with rectal cancer. J Gastrointest Surg (2010) 1.48
Detection of dysplasia in Barrett's esophagus with in vivo depth-resolved nuclear morphology measurements. Gastroenterology (2010) 1.48
Role of Nonsteroidal Anti-Inflammatory Drugs in Exacerbations of Inflammatory Bowel Disease. J Clin Gastroenterol (2016) 1.47
Diet, lifestyle, and genomic instability in the North Carolina Colon Cancer Study. Cancer Epidemiol Biomarkers Prev (2005) 1.45
Value of patient time invested in the colonoscopy screening process: time requirements for colonoscopy study. Med Decis Making (2008) 1.45
Longitudinal changes in lifestyle behaviors and health status in colon cancer survivors. Cancer Epidemiol Biomarkers Prev (2004) 1.45
Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study. Carcinogenesis (2006) 1.42
Comparative effectiveness of oxaliplatin vs non-oxaliplatin-containing adjuvant chemotherapy for stage III colon cancer. J Natl Cancer Inst (2012) 1.39
Research recruitment through US central cancer registries: balancing privacy and scientific issues. Am J Public Health (2006) 1.37
Identifying specific chemotherapeutic agents in Medicare data: a validation study. Med Care (2013) 1.36
Utilization of healthcare resources by U.S. children and adults with inflammatory bowel disease. Inflamm Bowel Dis (2011) 1.33
Social ties and colorectal cancer screening among Blacks and Whites in North Carolina. Cancer Epidemiol Biomarkers Prev (2005) 1.31
Genetic heterogeneity in colorectal cancer associations between African and European americans. Gastroenterology (2010) 1.31
Associations of micronutrients with colon cancer risk in African Americans and whites: results from the North Carolina Colon Cancer Study. Cancer Epidemiol Biomarkers Prev (2003) 1.29
Dietary patterns and self-reported associations of diet with symptoms of inflammatory bowel disease. Dig Dis Sci (2012) 1.27
Developing a sustainable process to provide quality control materials for genetic testing. Genet Med (2005) 1.23
Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers. Int J Cancer (2006) 1.22
Impact of the 2008-2009 economic recession on screening colonoscopy utilization among the insured. Clin Gastroenterol Hepatol (2011) 1.21
Impact of comorbidity on colorectal cancer screening in the veterans healthcare system. Clin Gastroenterol Hepatol (2007) 1.21
Peptic ulcer and bleeding events associated with rofecoxib in a 3-year colorectal adenoma chemoprevention trial. Gastroenterology (2006) 1.21
Modification of the natural history of adult-onset acid maltase deficiency by nutrition and exercise therapy. Muscle Nerve (2007) 1.20
Nonsteroidal anti-inflammatory drugs, apoptosis, and colorectal adenomas. Gastroenterology (2002) 1.20