Visualization and characterization of migratory Langerhans cells in murine skin and lymph nodes by antibodies against Langerin/CD207.

PubWeight™: 1.93‹?› | Rank: Top 3%

🔗 View Article (PMID 12542532)

Published in J Invest Dermatol on February 01, 2003

Authors

Patrizia Stoitzner1, Sandra Holzmann, Alexander D McLellan, Lennart Ivarsson, Hella Stössel, Michaela Kapp, Ulrike Kämmerer, Patrice Douillard, Eckhart Kämpgen, Franz Koch, Sem Saeland, Nikolaus Romani

Author Affiliations

1: Department of Dermatology, University of Innsbruck, Innsbruck, Austria. patrizia.stoitzner@uibk.ac.at

Articles citing this

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med (2005) 5.89

Identification of a novel population of Langerin+ dendritic cells. J Exp Med (2007) 4.13

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity. J Cell Biol (2005) 3.75

Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J Exp Med (2007) 3.64

The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med (2007) 3.24

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin. Immunol Rev (2010) 2.44

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J Exp Med (2006) 2.00

Langerhans cells cross-present antigen derived from skin. Proc Natl Acad Sci U S A (2006) 1.98

Layer-by-layer-assembled multilayer films for transcutaneous drug and vaccine delivery. ACS Nano (2009) 1.75

Resident and "inflammatory" dendritic cells in human skin. J Invest Dermatol (2008) 1.72

Epidermal Langerhans cells promote skin allograft rejection in mice with NF-kappa B-impaired T cells. Am J Transplant (2007) 1.55

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function. Mol Cell Biol (2005) 1.45

Adaptive immunity to fungi. Annu Rev Immunol (2012) 1.41

Production of monoclonal antibodies that recognize the extracellular domain of mouse langerin/CD207. J Immunol Methods (2007) 1.40

Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity. J Invest Dermatol (2010) 1.31

Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice. EMBO J (2004) 1.21

Vaginal epithelial dendritic cells renew from bone marrow precursors. Proc Natl Acad Sci U S A (2007) 1.21

A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS One (2013) 1.17

Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains. Immunology (2008) 1.10

Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol (2009) 1.10

Distinctive localization of antigen-presenting cells in human lymph nodes. Blood (2008) 1.08

Langerhans cells as targets for immunotherapy against skin cancer. Immunol Cell Biol (2010) 1.06

Roles for IL-1 and TNFalpha in dynamic behavioral responses of Langerhans cells to topical hapten application. J Dermatol Sci (2006) 0.98

Migration of skin dendritic cells in response to ionizing radiation exposure. Radiat Res (2009) 0.97

MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo. PLoS One (2009) 0.97

Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia. J Immunol (2013) 0.93

Comprehensive analysis of MHC-II expression in healthy human skin. Immunol Cell Biol (2007) 0.92

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses. Front Immunol (2015) 0.92

Langerhans cells and their role in oral mucosal diseases. N Am J Med Sci (2013) 0.90

Stress-induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: key role of intercellular adhesion molecule-1/leukocyte function-associated antigen interactions. Am J Pathol (2008) 0.88

The evolving function of Langerhans cells in adaptive skin immunity. Immunol Cell Biol (2010) 0.87

Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses. J Immunol (2012) 0.86

Matched skin and sentinel lymph node samples of melanoma patients reveal exclusive migration of mature dendritic cells. Am J Pathol (2005) 0.85

CD207+ Langerhans cells constitute a minor population of skin-derived antigen-presenting cells in the draining lymph node following exposure to Schistosoma mansoni. Int J Parasitol (2006) 0.80

Platelet-activating factor does not mediate UVB-induced local immune suppression. Photochem Photobiol (2012) 0.79

Nerve-Langerhans cell interactions in diabetes and aging. Histol Histopathol (2012) 0.79

Shikonin enhances efficacy of a gene-based cancer vaccine via induction of RANTES. J Biomed Sci (2012) 0.78

The bloodline of CD8α(+) dendritic cells. Mol Cells (2012) 0.75

Anti-inflammatory potential of Capparis spinosa L. in vivo in mice through inhibition of cell infiltration and cytokine gene expression. BMC Complement Altern Med (2017) 0.75

Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123. J Biol Chem (2010) 0.75

Langerhans cell-like dendritic cells stimulated with an adjuvant direct the development of Th1 and Th2 cells in vivo. Clin Exp Immunol (2015) 0.75

Articles by these authors

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity (2005) 6.48

Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity (2005) 4.06

Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells. Blood (2003) 3.40

Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes. Blood (2005) 2.47

DNA methylation in serum of breast cancer patients: an independent prognostic marker. Cancer Res (2003) 2.14

Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells. J Exp Med (2002) 2.07

Langerhans cells cross-present antigen derived from skin. Proc Natl Acad Sci U S A (2006) 1.98

Cutaneous dendritic cells. Semin Immunol (2005) 1.94

Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells. J Invest Dermatol (2005) 1.78

Ectopic expression of the murine chemokines CCL21a and CCL21b induces the formation of lymph node-like structures in pancreas, but not skin, of transgenic mice. J Immunol (2002) 1.74

Langerhans cells - dendritic cells of the epidermis. APMIS (2003) 1.64

Macrophages and dendritic cells constitute a major subpopulation of cells in the mouse dermis. J Invest Dermatol (2004) 1.60

The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling. J Leukoc Biol (2006) 1.59

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature. BMC Cancer (2009) 1.58

The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis. Blood (2013) 1.54

Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues. J Immunol (2002) 1.53

Increased expression of CCL20 in human inflammatory bowel disease. J Clin Immunol (2004) 1.50

Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin. J Immunol (2002) 1.49

Induction of exosome release in primary B cells stimulated via CD40 and the IL-4 receptor. J Immunol (2008) 1.46

Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function. Mol Cell Biol (2005) 1.45

A close-up view of migrating Langerhans cells in the skin. J Invest Dermatol (2002) 1.43

Ontogeny of Langerin/CD207 expression in the epidermis of mice. J Invest Dermatol (2004) 1.41

Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy. Am J Pathol (2003) 1.41

Negative regulation of Lck by Cbl ubiquitin ligase. Proc Natl Acad Sci U S A (2002) 1.40

Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells. J Allergy Clin Immunol (2007) 1.38

Is there a role for carbohydrate restriction in the treatment and prevention of cancer? Nutr Metab (Lond) (2011) 1.35

Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection. J Immunol (2006) 1.34

Anatomic location and T-cell stimulatory functions of mouse dendritic cell subsets defined by CD4 and CD8 expression. Blood (2002) 1.31

Isolation of dendritic cells. Curr Protoc Immunol (2009) 1.30

Expression of C-type lectin receptors by subsets of dendritic cells in human skin. Int Immunol (2004) 1.29

Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial. Nutr Metab (Lond) (2011) 1.27

Langerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells. Immunol Res (2003) 1.26

Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization. J Immunol (2007) 1.25

Langerhans cells are critical in the development of atopic dermatitis-like inflammation and symptoms in mice. J Cell Mol Med (2009) 1.24

Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance. J Reprod Immunol (2004) 1.22

Resolution of de novo HIV production and trafficking in immature dendritic cells. Nat Methods (2007) 1.21

Vaginal epithelial dendritic cells renew from bone marrow precursors. Proc Natl Acad Sci U S A (2007) 1.21

CD169 mediates the capture of exosomes in spleen and lymph node. Blood (2013) 1.20

Epidermal Langerhans cells--changing views on their function in vivo. Immunol Lett (2006) 1.18

Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma. BMC Cancer (2007) 1.14

Generation of an optimized polyvalent monocyte-derived dendritic cell vaccine by transfecting defined RNAs after rather than before maturation. J Immunol (2005) 1.14

A model system using tape stripping for characterization of Langerhans cell-precursors in vivo. J Invest Dermatol (2004) 1.13

Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation. J Invest Dermatol (2005) 1.12

A new way to generate cytolytic tumor-specific T cells: electroporation of RNA coding for a T cell receptor into T lymphocytes. Cancer Immunol Immunother (2005) 1.11

Network of dendritic cells within the muscular layer of the mouse intestine. Proc Natl Acad Sci U S A (2005) 1.10

Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas. Oncol Rep (2008) 1.10

Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol (2009) 1.10

Glycolipids injected into the skin are presented to NKT cells in the draining lymph node independently of migratory skin dendritic cells. J Immunol (2009) 1.10

Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains. Immunology (2008) 1.10

Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK. J Cancer Res Clin Oncol (2009) 1.10

High-risk human papilloma virus infection decreases the frequency of dendritic Langerhans' cells in the human female genital tract. Immunology (2006) 1.09

A novel role for IL-3: human monocytes cultured in the presence of IL-3 and IL-4 differentiate into dendritic cells that produce less IL-12 and shift Th cell responses toward a Th2 cytokine pattern. J Immunol (2002) 1.08

DNA methylation in serum and tumors of cervical cancer patients. Clin Cancer Res (2004) 1.06

Antigen-presenting cells and materno-fetal tolerance: an emerging role for dendritic cells. Am J Reprod Immunol (2007) 1.05

Effects of early atipamezole reversal of medetomidine-ketamine anesthesia in mice. J Am Assoc Lab Anim Sci (2011) 1.05

Lack of toxicity of therapy-induced T cell responses against the universal tumour antigen survivin. Vaccine (2005) 1.05

Characterization of antigen-presenting cells in fresh and cultured human corneas using novel dendritic cell markers. Invest Ophthalmol Vis Sci (2007) 1.05

Monocyte-derived dendritic cells release neopterin. J Leukoc Biol (2002) 1.04

Targeting of epidermal Langerhans cells with antigenic proteins: attempts to harness their properties for immunotherapy. Cancer Immunol Immunother (2008) 1.04

Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration. EMBO J (2003) 1.04

Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas. Eur Arch Otorhinolaryngol (2007) 1.03

Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma. Cancer Immunol Immunother (2012) 1.02

Analysis of maturation states of rat bone marrow-derived dendritic cells using an improved culture technique. Histochem Cell Biol (2002) 1.02

Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation. J Biol Chem (2007) 1.01

Structural studies of langerin and Birbeck granule: a macromolecular organization model. Biochemistry (2009) 1.00