Published in Circulation on January 28, 2003
Low Grade Inflammation, Gut Microbiota and Barrier Function in Elderly Humans | NCT01218165
Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH) | NCT02147457
Kefir and Metabolic Syndrome | NCT03649828
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C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the american heart association. Circulation (2011) 5.26
Childhood maltreatment predicts adult inflammation in a life-course study. Proc Natl Acad Sci U S A (2007) 4.58
Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. PLoS Med (2008) 4.34
Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res Rev (2008) 4.14
Systemic inflammation and disease progression in Alzheimer disease. Neurology (2009) 3.79
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ (2011) 3.65
Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med (2008) 3.54
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2014) 3.48
A comprehensive review on metabolic syndrome. Cardiol Res Pract (2014) 3.47
The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc (2012) 3.45
Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. Arch Pediatr Adolesc Med (2009) 3.41
Obesity, inflammation, and atherosclerosis. Nat Rev Cardiol (2009) 3.09
A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling. Biol Psychiatry (2008) 3.08
Laboratory markers in IBD: useful, magic, or unnecessary toys? Gut (2006) 3.00
To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers. Brain Behav Immun (2009) 3.00
Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the American Heart Association. J Am Coll Cardiol (2011) 2.89
Human C-reactive protein does not promote atherosclerosis in transgenic rabbits. Circulation (2009) 2.83
Socioeconomic status and health: the role of subjective social status. Soc Sci Med (2008) 2.82
Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch Gen Psychiatry (2008) 2.82
Uric acid and inflammatory markers. Eur Heart J (2006) 2.81
C-reactive protein in patients with COPD, control smokers and non-smokers. Thorax (2005) 2.72
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Am J Hum Genet (2005) 2.71
Mortality associated with short sleep duration: The evidence, the possible mechanisms, and the future. Sleep Med Rev (2009) 2.69
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. JAMA Psychiatry (2013) 2.68
Aging and vascular endothelial function in humans. Clin Sci (Lond) (2011) 2.53
C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart Study. Circ Cardiovasc Qual Outcomes (2008) 2.50
Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study. Biol Psychiatry (2007) 2.44
Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease. J Am Coll Cardiol (2008) 2.42
Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr (2013) 2.24
Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection. AIDS (2010) 2.22
Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential effect modification by nutrition. Environ Health Perspect (2006) 2.21
Biomarkers of inflammation and development of rheumatoid arthritis in women from two prospective cohort studies. Arthritis Rheum (2009) 2.19
Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigue. Brain Behav Immun (2007) 2.18
State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Circulation (2008) 2.17
Elevated C-reactive protein levels are associated with postoperative events in patients undergoing lower extremity vein bypass surgery. J Vasc Surg (2006) 2.14
Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. Int J Epidemiol (2008) 2.14
Association between dietary fiber and serum C-reactive protein. Am J Clin Nutr (2006) 2.07
Association of HIV infection and HIV/HCV coinfection with C-reactive protein levels: the fat redistribution and metabolic change in HIV infection (FRAM) study. J Acquir Immune Defic Syndr (2008) 2.05
Implications of increased C-reactive protein for cardiovascular risk stratification in black and white men and women in the US. Clin Chem (2009) 2.03
Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation (2009) 1.99
Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004. Am J Med (2008) 1.98
Prognostic effect size of cardiovascular biomarkers in datasets from observational studies versus randomised trials: meta-epidemiology study. BMJ (2011) 1.97
Association of C-reactive protein with type 2 diabetes: prospective analysis and meta-analysis. Diabetologia (2009) 1.96
A population-based dietary inflammatory index predicts levels of C-reactive protein in the Seasonal Variation of Blood Cholesterol Study (SEASONS). Public Health Nutr (2013) 1.93
Cumulative depression episodes predict later C-reactive protein levels: a prospective analysis. Biol Psychiatry (2011) 1.93
Associations between C-reactive protein and benign prostatic hyperplasia/lower urinary tract symptom outcomes in a population-based cohort. Am J Epidemiol (2009) 1.92
Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ (2005) 1.90
Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease. PLoS Med (2010) 1.89
A prospective evaluation of the directionality of the depression-inflammation relationship. Brain Behav Immun (2009) 1.88
CCR5 deletion protects against inflammation-associated mortality in dialysis patients. J Am Soc Nephrol (2009) 1.88
Health across the life span in the United States and England. Am J Epidemiol (2011) 1.88
Insulin resistance syndrome, body mass index and the risk of ischemic heart disease. CMAJ (2005) 1.86
High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease. Kidney Int (2011) 1.86
Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med (2006) 1.81
Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study. Circ Cardiovasc Genet (2009) 1.80
Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PLoS One (2011) 1.78
Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care (2013) 1.77
Assessing the role of circulating, genetic, and imaging biomarkers in cardiovascular risk prediction. Circulation (2011) 1.77
Assessing salivary C-reactive protein: longitudinal associations with systemic inflammation and cardiovascular disease risk in women exposed to intimate partner violence. Brain Behav Immun (2012) 1.77
Testicular cancer survivorship: research strategies and recommendations. J Natl Cancer Inst (2010) 1.76
Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study. BMC Public Health (2003) 1.74
Metabolic abnormalities and body composition of HIV-infected children on Lopinavir or Nevirapine-based antiretroviral therapy. Arch Dis Child (2012) 1.73
Sleep loss and inflammation. Best Pract Res Clin Endocrinol Metab (2010) 1.69
Association between dietary fiber and markers of systemic inflammation in the Women's Health Initiative Observational Study. Nutrition (2008) 1.69
Interpretation of serum C-reactive protein (CRP) levels for cardiovascular disease risk is complicated by race, pulmonary disease, body mass index, gender, and osteoarthritis. Osteoarthritis Cartilage (2007) 1.69
Child abuse is related to inflammation in mid-life women: role of obesity. Brain Behav Immun (2013) 1.68
Anti-depressant medication use and C-reactive protein: results from two population-based studies. Brain Behav Immun (2010) 1.65
C-reactive protein, inflammatory conditions, and cardiovascular disease risk. Am J Med (2007) 1.64
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid. Proc Natl Acad Sci U S A (2006) 1.63
Beef in an Optimal Lean Diet study: effects on lipids, lipoproteins, and apolipoproteins. Am J Clin Nutr (2011) 1.62
A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein. J Nutr (2009) 1.61
Inflammation, coronary artery calcification and cardiovascular events in incident renal transplant recipients. Atherosclerosis (2010) 1.60
Psychological distress and C-reactive protein: do health behaviours and pathophysiological factors modify the association? Eur Arch Psychiatry Clin Neurosci (2010) 1.60
Is depression an inflammatory disorder? Curr Psychiatry Rep (2011) 1.60
Periodontitis predicts elevated C-reactive protein levels in chronic kidney disease. J Dent Res (2011) 1.58
Individual pathogens, pathogen burden and markers of subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis. J Cardiovasc Med (Hagerstown) (2009) 1.57
C-reactive protein and risk of colorectal adenoma according to celecoxib treatment. Cancer Prev Res (Phila) (2011) 1.57
The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. BMC Genomics (2014) 1.57
Stress, age, and immune function: toward a lifespan approach. J Behav Med (2006) 1.56
The macrophage: the intersection between HIV infection and atherosclerosis. J Leukoc Biol (2009) 1.55
Markers of inflammation predict the long-term risk of developing chronic kidney disease: a population-based cohort study. Kidney Int (2011) 1.53
Plasma C-reactive protein in early pregnancy and preterm delivery. Am J Epidemiol (2005) 1.53
Racial differences in paraoxonase-1 (PON1): a factor in the health of southerners? Environ Health Perspect (2009) 1.53
Physical activity and mortality in chronic kidney disease (NHANES III). Clin J Am Soc Nephrol (2009) 1.52
Effect of exercise training on chronic inflammation. Clin Chim Acta (2010) 1.52
Periodontal disease and systemic conditions: a bidirectional relationship. Odontology (2006) 1.52
Early origins of inflammation: microbial exposures in infancy predict lower levels of C-reactive protein in adulthood. Proc Biol Sci (2009) 1.51
Association of socioeconomic status with inflammation markers in black and white men and women in the Coronary Artery Risk Development in Young Adults (CARDIA) study. Soc Sci Med (2009) 1.50
Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men. Atherosclerosis (2007) 1.50
The use of dried blood spot sampling in the national social life, health, and aging project. J Gerontol B Psychol Sci Soc Sci (2009) 1.49
Proinflammatory cytokines, sickness behavior, and Alzheimer disease. Neurology (2011) 1.48
Sedentary behaviour and biomarkers for cardiovascular disease and diabetes in mid-life: the role of television-viewing and sitting at work. PLoS One (2012) 1.48
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS One (2015) 1.48
Within-person variability in high-sensitivity C-reactive protein. Arch Intern Med (2012) 1.48
Metabolic syndrome and inflammatory responses to long-term particulate air pollutants. Environ Health Perspect (2008) 1.48
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Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol (2002) 35.63
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA (2003) 25.44
Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation (2004) 23.07
Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2007) 22.81
Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation (2004) 20.67
Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2006) 19.43
Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation (2010) 19.30
Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation (2007) 18.32
Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med (2006) 18.25
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 17.18
Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med (2002) 16.23
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2008) 15.35
Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA (2007) 15.32
Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2006) 14.72
Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation (2011) 14.00
Scientific evidence underlying the ACC/AHA clinical practice guidelines. JAMA (2009) 13.69
Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond. Circulation (2010) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Air pollution and cardiovascular disease: a statement for healthcare professionals from the Expert Panel on Population and Prevention Science of the American Heart Association. Circulation (2004) 13.07
Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2009) 12.34
Prevalence of autism spectrum disorders--Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. MMWR Surveill Summ (2012) 11.55
Recommendations for chamber quantification. Eur J Echocardiogr (2006) 11.39
Common values in assessing health outcomes from disease and injury: disability weights measurement study for the Global Burden of Disease Study 2010. Lancet (2012) 11.32
The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 10.24
Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet (2014) 10.06
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA (2007) 9.68
C-reactive protein levels and outcomes after statin therapy. N Engl J Med (2005) 9.47
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med (2003) 8.95
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 8.90
Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol (2003) 8.64
Third universal definition of myocardial infarction. J Am Coll Cardiol (2012) 8.59
Third universal definition of myocardial infarction. Circulation (2012) 8.47
Recommended community strategies and measurements to prevent obesity in the United States. MMWR Recomm Rep (2009) 8.43
Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation (2009) 8.11
AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation (2006) 8.01
Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98
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Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med (2002) 7.59
2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2010) 7.54
Plasma adiponectin levels and risk of myocardial infarction in men. JAMA (2004) 7.46
C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation (2008) 7.33
Improvements in diabetes processes of care and intermediate outcomes: United States, 1988-2002. Ann Intern Med (2006) 7.32