Chih-Yi Chen

Author PubWeight™ 122.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med 2007 10.47
2 MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell 2008 5.34
3 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet 2012 2.26
4 Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer 2003 2.01
5 Increased lung cancer risk among patients with pulmonary tuberculosis: a population cohort study. J Thorac Oncol 2011 1.99
6 Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci 2005 1.97
7 Single-incision thoracoscopic surgery for primary spontaneous pneumothorax. J Cardiothorac Surg 2011 1.95
8 The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet 2010 1.90
9 A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. J Natl Cancer Inst 2006 1.88
10 Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer 2006 1.82
11 Cigarette smoking induces overexpression of hepatocyte growth factor in type II pneumocytes and lung cancer cells. Am J Respir Cell Mol Biol 2005 1.57
12 The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients. J Clin Invest 2010 1.57
13 Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer. Cancer Res 2010 1.52
14 Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer Res 2010 1.44
15 Association of p53 codon 72 genotypes and clinical outcome in human papillomavirus-infected lung cancer patients. Ann Thorac Surg 2013 1.41
16 Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer. Int J Cancer 2005 1.38
17 Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas. Lung Cancer 2003 1.34
18 Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes. Clin Cancer Res 2006 1.29
19 Inflammatory myofibroblastic tumor of the lung--a case report. J Cardiothorac Surg 2010 1.27
20 Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. Lung Cancer 2008 1.25
21 Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. Cancer Res 2007 1.23
22 Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status. Ann Surg Oncol 2008 1.13
23 A randomized, controlled trial of fall prevention programs and quality of life in older fallers. J Am Geriatr Soc 2007 1.12
24 The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion. Oncogene 2005 1.10
25 A polymorphic -844T/C in FasL promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res 2011 1.09
26 Comparisons of the brief form of the World Health Organization Quality of Life and Short Form-36 for persons with spinal cord injuries. Am J Phys Med Rehabil 2007 1.09
27 Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples. J Clin Invest 2003 1.08
28 Impact of positive pleural lavage cytology on survival in patients having lung resection for non-small-cell lung cancer: An international individual patient data meta-analysis. J Thorac Cardiovasc Surg 2009 1.06
29 Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer. Clin Cancer Res 2011 1.05
30 Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer. Oncol Rep 2004 1.04
31 Effectiveness of different types of motorcycle helmets and effects of their improper use on head injuries. Int J Epidemiol 2011 1.03
32 IL-10 promotes tumor aggressiveness via upregulation of CIP2A transcription in lung adenocarcinoma. Clin Cancer Res 2013 1.02
33 Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol Cancer 2010 1.02
34 Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: a multiple genotype-phenotype study. Cancer 2009 1.02
35 Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway. Eur J Pharmacol 2004 0.98
36 Loss of TIMP-3 promotes tumor invasion via elevated IL-6 production and predicts poor survival and relapse in HPV-infected non-small cell lung cancer. Am J Pathol 2012 0.96
37 Dual roles of NOD2 in TLR4-mediated signal transduction and -induced inflammatory gene expression in macrophages. Cell Microbiol 2011 0.96
38 Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS One 2012 0.95
39 ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells. J Cell Sci 2010 0.95
40 HGF increases cisplatin resistance via down-regulation of AIF in lung cancer cells. Am J Respir Cell Mol Biol 2007 0.94
41 Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan. Lung Cancer 2003 0.93
42 Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells. Biochem Pharmacol 2004 0.93
43 Epidermal growth factor receptor mutation status in stage I lung adenocarcinoma with different image patterns. J Thorac Oncol 2011 0.93
44 Frequent p16INK4a promoter hypermethylation in human papillomavirus-infected female lung cancer in Taiwan. Int J Cancer 2005 0.91
45 Expression status of ribonucleotide reductase small subunits hRRM2/p53R2 as prognostic biomarkers in stage I and II non-small cell lung cancer. Anticancer Res 2011 0.90
46 Gender difference in human papillomarvirus infection for non-small cell lung cancer in Taiwan. Lung Cancer 2004 0.90
47 Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia. Hum Genet 2012 0.90
48 Clustered genomic alterations in chromosome 7p dictate outcomes and targeted treatment responses of lung adenocarcinoma with EGFR-activating mutations. J Clin Oncol 2011 0.90
49 Hospice shared-care saved medical expenditure and reduced the likelihood of intensive medical utilization among advanced cancer patients in Taiwan--a nationwide survey. Support Care Cancer 2014 0.89
50 Wild-type p53 overexpression and its correlation with MDM2 and p14ARF alterations: an alternative pathway to non-small-cell lung cancer. J Clin Oncol 2005 0.89
51 Quality of life predicts survival in patients with non-small cell lung cancer. BMC Public Health 2012 0.89
52 MnSOD promotes tumor invasion via upregulation of FoxM1-MMP2 axis and related with poor survival and relapse in lung adenocarcinomas. Mol Cancer Res 2012 0.89
53 Prognostic significance of caspase-3 expression in primary resected esophageal squamous cell carcinoma. Eur J Surg Oncol 2003 0.88
54 Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis. Clin Cancer Res 2008 0.88
55 Decreased survival among lung cancer patients with co-morbid tuberculosis and diabetes. BMC Cancer 2012 0.87
56 MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer. Clin Cancer Res 2012 0.87
57 Consistently lower narcotics consumption after video-assisted thoracoscopic surgery for early stage non-small cell lung cancer when compared to open surgery: a one-year follow-up study. Eur J Cardiothorac Surg 2012 0.86
58 p53 dysfunction by xeroderma pigmentosum group C defects enhance lung adenocarcinoma metastasis via increased MMP1 expression. Cancer Res 2010 0.86
59 The APE1 Asp/Asp genotype and the combination of APE1 Asp/Asp and hOGG1-Cys variants are associated with increased p53 mutation in non-small cell lung cancer. J Epidemiol 2012 0.86
60 Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53. DNA Repair (Amst) 2008 0.85
61 Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in stage I non-small-cell lung cancer patients with wild-type p53 tumors. Ann Surg Oncol 2009 0.85
62 Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus. World J Gastroenterol 2005 0.85
63 Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer. Oncol Rep 2007 0.85
64 Prognostic significance of intratumoral natural killer cells in primary resected esophageal squamous cell carcinoma. Chang Gung Med J 2005 0.85
65 Frequent FHIT gene loss of heterozygosity in human papillomavirus-infected non-smoking female lung cancer in Taiwan. Cancer Lett 2005 0.85
66 Relation between motorcycle helmet use and cervical spinal cord injury. Neuroepidemiology 2004 0.84
67 Association between expression of human papillomavirus 16/18 E6 oncoprotein and survival in patients with stage I non-small cell lung cancer. Oncol Rep 2009 0.84
68 Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma. Int J Cancer 2014 0.84
69 Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression. Carcinogenesis 2013 0.84
70 Potential increase in the prognostic value of p53 mutation by Pro72 allele in stage I non-small-cell lung cancer. Ann Surg Oncol 2009 0.83
71 Effect of fracture type on health-related quality of life among older women in Taiwan. Arch Phys Med Rehabil 2012 0.83
72 Re: Incidence of adenocarcinoma of the esophagus among white Americans by sex, stage, and age. J Natl Cancer Inst 2009 0.83
73 Reduced XPC messenger RNA level may predict a poor outcome of patients with nonsmall cell lung cancer. Cancer 2007 0.83
74 Alternative splicing of MDM2 mRNA in lung carcinomas and lung cell lines. Environ Mol Mutagen 2005 0.83
75 Alterations of the p16(ink4a) gene in resected nonsmall cell lung tumors and exfoliated cells within sputum. Int J Cancer 2002 0.83
76 Effects of fall injury type and discharge placement on mortality, hospitalization, falls, and ADL changes among older people in Taiwan. Accid Anal Prev 2012 0.83
77 Ganoderma tsugae Induces S Phase Arrest and Apoptosis in Doxorubicin-Resistant Lung Adenocarcinoma H23/0.3 Cells via Modulation of the PI3K/Akt Signaling Pathway. Evid Based Complement Alternat Med 2012 0.82
78 A 12-year-old boy with an infected ectopic ureter presenting with acute appendicitis-like symptoms and acute scrotum. Scand J Urol Nephrol 2012 0.82
79 EGFR L858R mutation and polymorphisms of genes related to estrogen biosynthesis and metabolism in never-smoking female lung adenocarcinoma patients. Clin Cancer Res 2011 0.82
80 Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis. Int J Med Sci 2013 0.82
81 Association of epidermal growth factor receptor mutations with human papillomavirus 16/18 E6 oncoprotein expression in non-small cell lung cancer. Cancer 2013 0.82
82 Expression of 53BP1 as a cisplatin-resistant marker in patients with lung adenocarcinomas. Oncol Rep 2010 0.81
83 EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients. Int J Cancer 2012 0.81
84 A polymorphism in the hMLH1 gene (-93G-->A) associated with lung cancer susceptibility and prognosis. Int J Mol Med 2010 0.81
85 p53R2 expression as a prognostic biomarker in early stage non-small cell lung cancer. Oncol Lett 2010 0.81
86 O6-Methylguanine-DNA methyltransferase hypermethylation modulated by 17beta-estradiol in lung cancer cells. Anticancer Res 2009 0.81
87 Rating scale, standard gamble, and time trade-off for people with traumatic spinal cord injuries. Phys Ther 2006 0.80
88 A prospective study of factors influencing return to work after traumatic spinal cord injury in Taiwan. Arch Phys Med Rehabil 2009 0.80
89 Different impact of IL10 haplotype on prognosis in lung squamous cell carcinoma and adenocarcinoma. Anticancer Res 2013 0.80
90 Caspase-14 is an anti-apoptotic protein targeting apoptosis-inducing factor in lung adenocarcinomas. Oncol Rep 2011 0.80
91 Extracts of Koelreuteria henryi Dummer induce apoptosis and autophagy by inhibiting dihydrodiol dehydrogenase, thus enhancing anticancer effects. Int J Mol Med 2013 0.80
92 Loss of heterozygosity at loci of candidate tumor suppressor genes in microdissected primary non-small cell lung cancer. Cancer Detect Prev 2002 0.80
93 Color Doppler US pulmonary artery vessel signal: a sign for predicting the benign lesions. Ultrasound Med Biol 2007 0.79
94 Revisit of 1997 TNM staging system--survival analysis of 1112 lung cancer patients in Taiwan. Jpn J Clin Oncol 2006 0.79
95 Prognostic significance of X-ray cross-complementing group 1 T-77C polymorphism in resected non-small cell lung cancer. Jpn J Clin Oncol 2008 0.79
96 Nickel accumulation in lung tissues is associated with increased risk of p53 mutation in lung cancer patients. Environ Mol Mutagen 2014 0.79
97 Expression of xeroderma pigmentosum complementation group C protein predicts cisplatin resistance in lung adenocarcinoma patients. Oncol Rep 2011 0.79
98 5' cytosine-phospho-guanine island methylation is responsible for p14ARF inactivation and inversely correlates with p53 overexpression in resected non-small cell lung cancer. Clin Cancer Res 2004 0.78
99 A possible role for dihydrodiol dehydrogenase in the formation of benzo[a]pyrene-DNA adducts in lung cancer cells and tumor tissues. Environ Mol Mutagen 2007 0.78
100 Impact of the new lung cancer staging system for a predominantly advanced-disease patient population. J Thorac Oncol 2010 0.78
101 Clinical significance of bone marrow microinvolvement in nonsmall cell lung carcinoma. Cancer 2004 0.78
102 Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells. Hum Pathol 2011 0.78
103 5'CpG island hypermethylation and aberrant transcript splicing both contribute to the inactivation of the FHIT gene in resected non-small cell lung cancer. Eur J Cancer 2004 0.78
104 Shorter-time dual-phase FDG PET/CT in characterizing solid or ground-glass nodules based on surgical results. Clin Imaging 2012 0.77
105 XPC mRNA level may predict relapse in never-smokers with non-small cell lung cancers. Ann Surg Oncol 2011 0.77
106 Cell type-specific effects of Adenosine 5'-triphosphate and pyrophosphate on the antitumor activity of doxorubicin. Cancer Sci 2012 0.76
107 Comparisons of Different Screening Tools for Identifying Fracture/Osteoporosis Risk Among Community-Dwelling Older People. Medicine (Baltimore) 2016 0.76
108 Search for novel remedies to augment radiation resistance of inhabitants of Fukushima and Chernobyl disasters: identifying DNA repair protein XRCC4 inhibitors. J Biomol Struct Dyn 2011 0.76
109 Re: Intensity-modulated radiation therapy dose prescription, recording, and delivery: patterns of variability among institutions and treatment planning systems. J Natl Cancer Inst 2008 0.75
110 Rare presentation of pulmonary cryptococcosis as a calcified nodule. Intern Med 2011 0.75
111 Outpatient thoracoscopic sympathicotomy for axillary osmidrosis. Eur J Cardiothorac Surg 2003 0.75
112 The influence of health behaviors on survival in lung cancer patients in Taiwan. Jpn J Clin Oncol 2010 0.75
113 [Clinical significance of limited resection in lung cancer surgery.]. Zhongguo Fei Ai Za Zhi 2008 0.75
114 Pulmonary sequestration after resection of contralateral congenital pulmonary sequestration. Eur J Cardiothorac Surg 2012 0.75
115 Pleura detection in chest computed tomography with application for nodule detection. Conf Proc IEEE Eng Med Biol Soc 2013 0.75
116 Adult unilateral pulmonary lucency. Intern Med 2012 0.75
117 Interactions between household air pollution and GWAS-identified lung cancer susceptibility markers in the Female Lung Cancer Consortium in Asia (FLCCA). Hum Genet 2015 0.75
118 Estrogen Receptor Gene Polymorphisms and Lung Adenocarcinoma Risk in Never-Smoking Women. J Thorac Oncol 2015 0.75