Loss of telomerase activity may be a potential favorable prognostic marker in lung carcinomas.

PubWeight™: 1.34‹?› | Rank: Top 10%

🔗 View Article (PMID 12871779)

Published in Lung Cancer on August 01, 2003

Authors

Tzu-Chin Wu1, Pinpin Lin, Chung-Ping Hsu, Yi-Jie Huang, Chih-Yi Chen, Wen-Chuan Chung, Huei Lee, Jiunn-Liang Ko

Author Affiliations

1: Division of Chest Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.

Articles citing this

Lung cancer susceptibility locus at 5p15.33. Nat Genet (2008) 5.99

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18

Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br J Cancer (2006) 1.44

The TERT rs2736100 polymorphism and cancer risk: a meta-analysis based on 25 case-control studies. BMC Cancer (2012) 0.93

Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women. J Cancer Epidemiol (2010) 0.90

Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer. PLoS One (2012) 0.86

Clinical significance of telomerase and its associate genes expression in the maintenance of telomere length in squamous cell carcinoma of the esophagus. World J Gastroenterol (2005) 0.85

Telomere length and recurrence risk after curative resection in patients with early-stage non-small-cell lung cancer: a prospective cohort study. J Thorac Oncol (2015) 0.83

Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma. World J Gastroenterol (2003) 0.83

Prognostic implication of telomerase activity in patients with brain tumors. J Korean Med Sci (2006) 0.78

The associations of TERT-CLPTM1L variants and TERT mRNA expression with the prognosis of early stage non-small cell lung cancer. Cancer Gene Ther (2016) 0.75

Articles by these authors

Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 13.00

A five-gene signature and clinical outcome in non-small-cell lung cancer. N Engl J Med (2007) 10.47

MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell (2008) 5.34

Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res (2005) 4.25

PIK3CA mutations and copy number gains in human lung cancers. Cancer Res (2008) 3.42

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26

Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer (2003) 2.01

Increased lung cancer risk among patients with pulmonary tuberculosis: a population cohort study. J Thorac Oncol (2011) 1.99

Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci (2005) 1.97

Single-incision thoracoscopic surgery for primary spontaneous pneumothorax. J Cardiothorac Surg (2011) 1.95

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90

A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. J Natl Cancer Inst (2006) 1.88

Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer (2006) 1.82

Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women. Cancer Epidemiol Biomarkers Prev (2010) 1.74

Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment. Environ Health Perspect (2007) 1.61

Cigarette smoking induces overexpression of hepatocyte growth factor in type II pneumocytes and lung cancer cells. Am J Respir Cell Mol Biol (2005) 1.57

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients. J Clin Invest (2010) 1.57

Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer. Cancer Res (2010) 1.52

Spontaneous hemopneumothorax revisited: clinical approach and systemic review of the literature. Ann Thorac Surg (2005) 1.45

Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer Res (2010) 1.44

Association of p53 codon 72 genotypes and clinical outcome in human papillomavirus-infected lung cancer patients. Ann Thorac Surg (2013) 1.41

Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer. Int J Cancer (2005) 1.38

Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter--effect on telomerase expression and telomere length maintenance in non-small cell lung cancer. Eur J Cancer (2006) 1.34

Identification of alpha-enolase as an autoantigen in lung cancer: its overexpression is associated with clinical outcomes. Clin Cancer Res (2006) 1.29

Inflammatory myofibroblastic tumor of the lung--a case report. J Cardiothorac Surg (2010) 1.27

Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. Lung Cancer (2008) 1.25

Oxidative DNA damage in pterygium. Mol Vis (2005) 1.23

Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation. Cancer Res (2007) 1.23

Integrated analyses of copy number variations and gene expression in lung adenocarcinoma. PLoS One (2011) 1.19

Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade. Cancer Sci (2012) 1.14

Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status. Ann Surg Oncol (2008) 1.13

A randomized, controlled trial of fall prevention programs and quality of life in older fallers. J Am Geriatr Soc (2007) 1.12

The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion. Oncogene (2005) 1.10

Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway. Cancer Res (2004) 1.10

A polymorphic -844T/C in FasL promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res (2011) 1.09

Comparisons of the brief form of the World Health Organization Quality of Life and Short Form-36 for persons with spinal cord injuries. Am J Phys Med Rehabil (2007) 1.09

Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples. J Clin Invest (2003) 1.08

Carcinoma arising from an epiphrenic diverticulum: a frequently misdiagnosed disease. Ann Thorac Cardiovasc Surg (2007) 1.08

Accumulation of chromium and nickel metals in lung tumors from lung cancer patients in Taiwan. J Toxicol Environ Health A (2006) 1.07

Matrix metalloproteinase-13 expression is associated with bone marrow microinvolvement and prognosis in non-small cell lung cancer. Lung Cancer (2006) 1.07

Impact of positive pleural lavage cytology on survival in patients having lung resection for non-small-cell lung cancer: An international individual patient data meta-analysis. J Thorac Cardiovasc Surg (2009) 1.06

The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer. Clin Cancer Res (2007) 1.06

Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer. Clin Cancer Res (2011) 1.05

Light regulation of asexual development in the rice blast fungus, Magnaporthe oryzae. Fungal Genet Biol (2006) 1.05

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review. Am J Epidemiol (2009) 1.04

Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer. Oncol Rep (2004) 1.04

cIAP2 upregulated by E6 oncoprotein via epidermal growth factor receptor/phosphatidylinositol 3-kinase/AKT pathway confers resistance to cisplatin in human papillomavirus 16/18-infected lung cancer. Clin Cancer Res (2010) 1.03

Arsenic promotes centrosome abnormalities and cell colony formation in p53 compromised human lung cells. Toxicol Appl Pharmacol (2007) 1.03

The presence of human papillomavirus type 16/18 DNA in blood circulation may act as a risk marker of lung cancer in Taiwan. Cancer (2003) 1.03

Effectiveness of different types of motorcycle helmets and effects of their improper use on head injuries. Int J Epidemiol (2011) 1.03

Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol Cancer (2010) 1.02

IL-10 promotes tumor aggressiveness via upregulation of CIP2A transcription in lung adenocarcinoma. Clin Cancer Res (2013) 1.02

Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas. Clin Cancer Res (2007) 1.02

Lung cancer susceptibility and prognosis associated with polymorphisms in the nonhomologous end-joining pathway genes: a multiple genotype-phenotype study. Cancer (2009) 1.02

Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion. Mol Carcinog (2010) 1.02

Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity. Food Chem Toxicol (2011) 1.02

CD133+ glioblastoma stem-like cells induce vascular mimicry in vivo. Curr Neurovasc Res (2011) 1.00

Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma. J Pathol (2013) 1.00

Genetic determinants of pemetrexed responsiveness and nonresponsiveness in non-small cell lung cancer cells. J Thorac Oncol (2010) 0.98

An association of DNMT3b protein expression with P16INK4a promoter hypermethylation in non-smoking female lung cancer with human papillomavirus infection. Cancer Lett (2005) 0.98

Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway. Eur J Pharmacol (2004) 0.98

Gender difference in the prognostic role of interleukin 6 in oral squamous cell carcinoma. PLoS One (2012) 0.97

Gender difference in estrogen receptor alpha promoter hypermethylation and its prognostic value in non-small cell lung cancer. Int J Cancer (2005) 0.97

Effect of TIMP-1 and MMP in pterygium invasion. Invest Ophthalmol Vis Sci (2010) 0.97

Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol (2012) 0.97

The use of radioactive zinc oxide nanoparticles in determination of their tissue concentrations following intravenous administration in mice. Analyst (2010) 0.97

Dual roles of NOD2 in TLR4-mediated signal transduction and -induced inflammatory gene expression in macrophages. Cell Microbiol (2011) 0.96

Loss of TIMP-3 promotes tumor invasion via elevated IL-6 production and predicts poor survival and relapse in HPV-infected non-small cell lung cancer. Am J Pathol (2012) 0.96

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines. Toxicol Lett (2007) 0.96

Exposure to mosquito coil smoke may be a risk factor for lung cancer in Taiwan. J Epidemiol (2008) 0.95

ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells. J Cell Sci (2010) 0.95

Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS One (2012) 0.95

ZAK inhibits human lung cancer cell growth via ERK and JNK activation in an AP-1-dependent manner. Cancer Sci (2010) 0.95

GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells. Autophagy (2011) 0.95

Pulmonary sequestration-differences in diagnosis and treatment in a single institution. J Chin Med Assoc (2013) 0.95

The mechanisms of action of Tianhua(™) on antitumor activity in lung cancer cells. Pharm Biol (2010) 0.94

High expression of interleukin 10 might predict poor prognosis in early stage oral squamous cell carcinoma patients. Clin Chim Acta (2012) 0.94

HGF increases cisplatin resistance via down-regulation of AIF in lung cancer cells. Am J Respir Cell Mol Biol (2007) 0.94

P53 gene mutation spectrum and the relationship between gene mutation and protein levels in pterygium. Mol Vis (2005) 0.94

Genetic polymorphisms of oxidative and antioxidant enzymes and arsenic-related hypertension. J Toxicol Environ Health A (2005) 0.94

Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan. Lung Cancer (2003) 0.93

Epigenetic effects and molecular mechanisms of tumorigenesis induced by cigarette smoke: an overview. J Oncol (2011) 0.93

Epidermal growth factor receptor mutation status in stage I lung adenocarcinoma with different image patterns. J Thorac Oncol (2011) 0.93

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, enhances radiosensitivity and suppresses lung metastasis in breast cancer in vitro and in vivo. PLoS One (2013) 0.93

Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells. Biochem Pharmacol (2004) 0.93