Published in J Biol Chem on January 31, 2003
Yeast prions [URE3] and [PSI+] are diseases. Proc Natl Acad Sci U S A (2005) 2.45
The prion hypothesis: from biological anomaly to basic regulatory mechanism. Nat Rev Mol Cell Biol (2010) 2.22
Moonlighting proteins in yeasts. Microbiol Mol Biol Rev (2008) 1.36
Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts. Eukaryot Cell (2004) 1.26
Recent advances in nitrogen regulation: a comparison between Saccharomyces cerevisiae and filamentous fungi. Eukaryot Cell (2008) 1.14
Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae. J Biol Chem (2004) 1.12
Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. J Biol Chem (2003) 1.11
Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation. J Biol Chem (2007) 1.09
A peroxisomal glutathione transferase of Saccharomyces cerevisiae is functionally related to sulfur amino acid metabolism. Eukaryot Cell (2006) 0.97
Novel glutaredoxin activity of the yeast prion protein Ure2 reveals a native-like dimer within fibrils. J Biol Chem (2009) 0.92
Perspectives for genetic engineering of poplars for enhanced phytoremediation abilities. Ecotoxicology (2010) 0.88
Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2. Philos Trans R Soc Lond B Biol Sci (2013) 0.87
Yeast prions assembly and propagation: contributions of the prion and non-prion moieties and the nature of assemblies. Prion (2011) 0.84
Transcriptomic responses of the basidiomycete yeast Sporobolomyces sp. to the mycotoxin patulin. BMC Genomics (2016) 0.84
Reverse genetic analysis of the glutathione metabolic pathway suggests a novel role of PHGPX and URE2 genes in aluminum resistance in Saccharomyces cerevisiae. Mol Genet Genomics (2004) 0.84
Synergistic operation of four cis-acting elements mediate high level DAL5 transcription in Saccharomyces cerevisiae. FEMS Yeast Res (2004) 0.84
In vivo specificity of Ure2 protection from heavy metal ion and oxidative cellular damage in Saccharomyces cerevisiae. Yeast (2005) 0.81
Ure2 is involved in nitrogen catabolite repression and salt tolerance via Ca2+ homeostasis and calcineurin activation in the yeast Hansenula polymorpha. J Biol Chem (2010) 0.77
Engineering microbial phenotypes through rewiring of genetic networks. Nucleic Acids Res (2017) 0.75
Identification of glutathione S-transferase (GST) genes from a dark septate endophytic fungus (Exophiala pisciphila) and their expression patterns under varied metals stress. PLoS One (2015) 0.75
[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae. Science (1994) 10.94
Regulation of pyrimidine biosynthesis in Saccharomyces cerevisiae. J Bacteriol (1968) 5.26
The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases. Mol Cell Biol (1991) 3.52
Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots. FEMS Microbiol Rev (2002) 2.90
[URE3] prion propagation in Saccharomyces cerevisiae: requirement for chaperone Hsp104 and curing by overexpressed chaperone Ydj1p. Mol Cell Biol (2000) 2.83
The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem (1996) 2.75
Prion domain initiation of amyloid formation in vitro from native Ure2p. Science (1999) 2.67
A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmium. Proc Natl Acad Sci U S A (1997) 2.66
Nitrogen catabolite repression in Saccharomyces cerevisiae. Mol Biotechnol (1999) 2.05
Ureidosuccinic acid uptake in yeast and some aspects of its regulation. J Bacteriol (1972) 1.98
The prion model for [URE3] of yeast: spontaneous generation and requirements for propagation. Proc Natl Acad Sci U S A (1997) 1.91
Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem J (1998) 1.76
Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae. Curr Biol (2002) 1.54
Two prion-inducing regions of Ure2p are nonoverlapping. Mol Cell Biol (1999) 1.53
Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae. J Biol Chem (2000) 1.43
Genome-wide transcriptional analysis in S. cerevisiae by mini-array membrane hybridization. Yeast (1999) 1.41
Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression. J Biol Chem (2002) 1.37
A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage. J Neurosci (2002) 1.37
G1n3p is capable of binding to UAS(NTR) elements and activating transcription in Saccharomyces cerevisiae. J Bacteriol (1996) 1.36
Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae. Genetics (1999) 1.34
A protein required for prion generation: [URE3] induction requires the Ras-regulated Mks1 protein. Proc Natl Acad Sci U S A (2000) 1.34
The yeast prion Ure2p retains its native alpha-helical conformation upon assembly into protein fibrils in vitro. EMBO J (2002) 1.31
The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. Proc Natl Acad Sci U S A (2001) 1.31
Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae. Structure (2001) 1.29
Formation of disulfides with diamide. Methods Enzymol (1987) 1.28
Equilibrium folding properties of the yeast prion protein determinant Ure2. J Mol Biol (1999) 1.25
A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae. J Biol Chem (1998) 1.23
GDH3 encodes a glutamate dehydrogenase isozyme, a previously unrecognized route for glutamate biosynthesis in Saccharomyces cerevisiae. J Bacteriol (1997) 1.22
RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3]. Mol Biol Cell (2002) 1.18
Stability, folding, dimerization, and assembly properties of the yeast prion Ure2p. Biochemistry (2001) 1.17
Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds. Biochemistry (2001) 1.10
The level of DAL80 expression down-regulates GATA factor-mediated transcription in Saccharomyces cerevisiae. J Bacteriol (2000) 1.02
A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Appl Environ Microbiol (2002) 1.01
Purification and characterization of a recombinant human Theta-class glutathione transferase (GSTT2-2). Biochem J (1996) 1.00
Distinct roles for glutathione S-transferases in the oxidative stress response in Schizosaccharomyces pombe. J Biol Chem (2002) 1.00
A novel Rtg2p activity regulates nitrogen catabolism in yeast. Proc Natl Acad Sci U S A (2001) 0.91
Characterization, expression and regulation of a third gene encoding glutathione S-transferase from the fission yeast. Biochim Biophys Acta (2002) 0.78
Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated by rapamycin inhibition of Tor1/2 in Saccharomyces cerevisiae. J Biol Chem (2003) 1.52
Cytoplasmic compartmentation of Gln3 during nitrogen catabolite repression and the mechanism of its nuclear localization during carbon starvation in Saccharomyces cerevisiae. J Biol Chem (2002) 1.40
Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression. J Biol Chem (2002) 1.37
Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain. J Biol Chem (2006) 1.23
Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae. J Biol Chem (2005) 1.18
Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae. J Biol Chem (2008) 1.17
Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae. J Biol Chem (2004) 1.12
Differing responses of Gat1 and Gln3 phosphorylation and localization to rapamycin and methionine sulfoximine treatment in Saccharomyces cerevisiae. FEMS Yeast Res (2006) 1.11
Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. J Biol Chem (2003) 1.11
Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation. J Biol Chem (2007) 1.09
Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently. J Biol Chem (2008) 1.05
Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes. Genetics (2008) 1.02
Structure theorems and the dynamics of nitrogen catabolite repression in yeast. Proc Natl Acad Sci U S A (2005) 1.02
Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression and rapamycin treatment in Saccharomyces cerevisiae. J Biol Chem (2010) 1.01
Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine. J Biol Chem (2011) 1.00
gln3 mutations dissociate responses to nitrogen limitation (nitrogen catabolite repression) and rapamycin inhibition of TorC1. J Biol Chem (2012) 0.94
Ammonia-specific regulation of Gln3 localization in Saccharomyces cerevisiae by protein kinase Npr1. J Biol Chem (2006) 0.93
Five conditions commonly used to down-regulate tor complex 1 generate different physiological situations exhibiting distinct requirements and outcomes. J Biol Chem (2013) 0.91
Formalin can alter the intracellular localization of some transcription factors in Saccharomyces cerevisiae. FEMS Yeast Res (2008) 0.90
Binding and activation by the zinc cluster transcription factors of Saccharomyces cerevisiae. Redefining the UASGABA and its interaction with Uga3p. J Biol Chem (2002) 0.86
Intranuclear function for protein phosphatase 2A: Pph21 and Pph22 are required for rapamycin-induced GATA factor binding to the DAL5 promoter in yeast. Mol Cell Biol (2010) 0.86
Alterations in the Ure2 αCap domain elicit different GATA factor responses to rapamycin treatment and nitrogen limitation. J Biol Chem (2012) 0.86
Synergistic operation of four cis-acting elements mediate high level DAL5 transcription in Saccharomyces cerevisiae. FEMS Yeast Res (2004) 0.84
In vivo specificity of Ure2 protection from heavy metal ion and oxidative cellular damage in Saccharomyces cerevisiae. Yeast (2005) 0.81
Components of Golgi-to-vacuole trafficking are required for nitrogen- and TORC1-responsive regulation of the yeast GATA factors. Microbiologyopen (2014) 0.79
Constitutive and nitrogen catabolite repression-sensitive production of Gat1 isoforms. J Biol Chem (2013) 0.76
Premature termination of GAT1 transcription explains paradoxical negative correlation between nitrogen-responsive mRNA, but constitutive low-level protein production. RNA Biol (2015) 0.75
Editorial: Retrospectives - lives behind the science. FEMS Yeast Res (2016) 0.75
Piotr P. Slonimski - The Warrior Pope: The discovery of mitochondrial (petite) mutants and split genes. FEMS Yeast Res (2016) 0.75
What do the pictures say - snapshots of a career. FEMS Yeast Res (2017) 0.75