Published in Nat Rev Drug Discov on February 01, 2003
Agr-mediated dispersal of Staphylococcus aureus biofilms. PLoS Pathog (2008) 3.91
Involvement of nitric oxide in biofilm dispersal of Pseudomonas aeruginosa. J Bacteriol (2006) 2.97
Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms. PLoS Pathog (2008) 2.71
Sticking together: building a biofilm the Bacillus subtilis way. Nat Rev Microbiol (2013) 2.68
Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05
Metabolic co-dependence gives rise to collective oscillations within biofilms. Nature (2015) 1.92
Peptide signaling in the staphylococci. Chem Rev (2010) 1.89
Infection of orthopedic implants with emphasis on bacterial adhesion process and techniques used in studying bacterial-material interactions. Biomatter (2013) 1.72
Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide. Antimicrob Agents Chemother (2012) 1.63
Proteomic analysis of Campylobacter jejuni 11168 biofilms reveals a role for the motility complex in biofilm formation. J Bacteriol (2006) 1.62
Bacterial biofilm shows persistent resistance to liquid wetting and gas penetration. Proc Natl Acad Sci U S A (2010) 1.62
The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage. ISME J (2008) 1.58
Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection. Antimicrob Agents Chemother (2003) 1.56
Gentamicin promotes Staphylococcus aureus biofilms on silk suture. J Surg Res (2011) 1.53
Small molecule control of bacterial biofilms. Org Biomol Chem (2012) 1.51
Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology. PLoS Pathog (2015) 1.49
Combinatorial discovery of polymers resistant to bacterial attachment. Nat Biotechnol (2012) 1.46
Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism. PLoS Genet (2012) 1.46
Multiple applications of Alamar Blue as an indicator of metabolic function and cellular health in cell viability bioassays. Sensors (Basel) (2012) 1.43
Effect of DNase and antibiotics on biofilm characteristics. Antimicrob Agents Chemother (2008) 1.42
The extracellular matrix Component Psl provides fast-acting antibiotic defense in Pseudomonas aeruginosa biofilms. PLoS Pathog (2013) 1.42
The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent. Proc Natl Acad Sci U S A (2008) 1.41
New device for high-throughput viability screening of flow biofilms. Appl Environ Microbiol (2010) 1.41
Detection of a microbial biofilm in intraamniotic infection. Am J Obstet Gynecol (2008) 1.37
Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein-protein interaction. EMBO J (2012) 1.36
A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra-amniotic infection in preterm labor with intact membranes. Am J Reprod Immunol (2014) 1.32
Evolution of resistance to quorum-sensing inhibitors. Microb Ecol (2013) 1.27
Altering the ratio of phenazines in Pseudomonas chlororaphis (aureofaciens) strain 30-84: effects on biofilm formation and pathogen inhibition. J Bacteriol (2008) 1.26
Bacterial flagella explore microscale hummocks and hollows to increase adhesion. Proc Natl Acad Sci U S A (2013) 1.22
Brominated furanones inhibit biofilm formation by Salmonella enterica serovar Typhimurium. Appl Environ Microbiol (2008) 1.22
A small subpopulation of blastospores in candida albicans biofilms exhibit resistance to amphotericin B associated with differential regulation of ergosterol and beta-1,6-glucan pathway genes. Antimicrob Agents Chemother (2006) 1.22
Density of founder cells affects spatial pattern formation and cooperation in Bacillus subtilis biofilms. ISME J (2014) 1.21
Liquid-infused structured surfaces with exceptional anti-biofouling performance. Proc Natl Acad Sci U S A (2012) 1.21
Noninvasive biophotonic imaging for monitoring of catheter-associated urinary tract infections and therapy in mice. Infect Immun (2005) 1.20
A three-dimensional computer model of four hypothetical mechanisms protecting biofilms from antimicrobials. Appl Environ Microbiol (2006) 1.19
Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide. BMC Microbiol (2010) 1.16
Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics. Microbiol Mol Biol Rev (2014) 1.16
In vitro modeling of host-parasite interactions: the 'subgingival' biofilm challenge of primary human epithelial cells. BMC Microbiol (2009) 1.15
Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections. Proc Natl Acad Sci U S A (2014) 1.14
Type IV pili and the CcpA protein are needed for maximal biofilm formation by the gram-positive anaerobic pathogen Clostridium perfringens. Infect Immun (2008) 1.14
Challenges in microbial ecology: building predictive understanding of community function and dynamics. ISME J (2016) 1.12
Analysis of bacterial biofilms using NMR-based metabolomics. Future Med Chem (2012) 1.11
Methicillin resistance and the biofilm phenotype in Staphylococcus aureus. Front Cell Infect Microbiol (2015) 1.09
A new small molecule specifically inhibits the cariogenic bacterium Streptococcus mutans in multispecies biofilms. Antimicrob Agents Chemother (2011) 1.08
Microbial biofilms on the surface of intravaginal rings worn in non-human primates. J Med Microbiol (2011) 1.07
Surface-localized spermidine protects the Pseudomonas aeruginosa outer membrane from antibiotic treatment and oxidative stress. J Bacteriol (2011) 1.07
Interspecific bacterial sensing through airborne signals modulates locomotion and drug resistance. Nat Commun (2013) 1.06
A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance. J Bacteriol (2012) 1.05
Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs-A Review. Pathogens (2014) 1.05
Correlated biofilm imaging, transport and metabolism measurements via combined nuclear magnetic resonance and confocal microscopy. ISME J (2007) 1.04
Polysorbate 80 inhibition of Pseudomonas aeruginosa biofilm formation and its cleavage by the secreted lipase LipA. Antimicrob Agents Chemother (2008) 1.04
Biofilms and Inflammation in Chronic Wounds. Adv Wound Care (New Rochelle) (2013) 1.03
The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Antimicrob Agents Chemother (2012) 1.02
The polyketide Pks1 contributes to biofilm formation in Mycobacterium tuberculosis. J Bacteriol (2011) 1.02
Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity. J Med Chem (2009) 1.01
A naturally occurring brominated furanone covalently modifies and inactivates LuxS. Bioorg Med Chem Lett (2009) 0.99
Antibiofilm activity of an exopolysaccharide from marine bacterium Vibrio sp. QY101. PLoS One (2011) 0.99
6-Gingerol reduces Pseudomonas aeruginosa biofilm formation and virulence via quorum sensing inhibition. Sci Rep (2015) 0.99
Peptide design for antimicrobial and immunomodulatory applications. Biopolymers (2013) 0.99
Detection of bacterial biofilms in different types of chronic otitis media. Eur Arch Otorhinolaryngol (2013) 0.98
Klebsiella pneumoniae: Going on the Offense with a Strong Defense. Microbiol Mol Biol Rev (2016) 0.98
Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant staphylococci. J Antibiot (Tokyo) (2014) 0.97
A radio frequency electric current enhances antibiotic efficacy against bacterial biofilms. Antimicrob Agents Chemother (2004) 0.97
The cation-responsive protein NhaR of Escherichia coli activates pgaABCD transcription, required for production of the biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine. J Bacteriol (2006) 0.97
Abolition of biofilm formation in urinary tract Escherichia coli and Klebsiella isolates by metal interference through competition for fur. Appl Environ Microbiol (2010) 0.97
Interplay of physical mechanisms and biofilm processes: review of microfluidic methods. Lab Chip (2015) 0.96
Effect of tetracycline on transfer and establishment of the tetracycline-inducible conjugative transposon Tn916 in the guts of gnotobiotic rats. Appl Environ Microbiol (2004) 0.96
Drosophila melanogaster as an animal model for the study of Pseudomonas aeruginosa biofilm infections in vivo. PLoS Pathog (2011) 0.96
Will biofilm disassembly agents make it to market? Trends Microbiol (2011) 0.96
Thromboresistant/anti-biofilm catheters via electrochemically modulated nitric oxide release. Bioelectrochemistry (2014) 0.94
Relation between antibiotic susceptibility and ultrastructure of Staphylococcus aureus biofilms on surgical suture. Surg Infect (Larchmt) (2011) 0.94
Antibiofilm activity of GlmU enzyme inhibitors against catheter-associated uropathogens. Antimicrob Agents Chemother (2006) 0.94
Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study. Bioorg Med Chem (2012) 0.94
Gene expression profile and pathogenicity of biofilm-forming Prevotella intermedia strain 17. BMC Microbiol (2009) 0.93
The pharmaco -, population and evolutionary dynamics of multi-drug therapy: experiments with S. aureus and E. coli and computer simulations. PLoS Pathog (2013) 0.93
Staphylococcus aureus biofilms promote horizontal transfer of antibiotic resistance. Antimicrob Agents Chemother (2013) 0.93
Ginger extract inhibits biofilm formation by Pseudomonas aeruginosa PA14. PLoS One (2013) 0.93
Influence of culture heterogeneity in cell surface charge on adhesion and biofilm formation by Enterococcus faecalis. J Bacteriol (2006) 0.92
Influence of the diversity of bacterial isolates from drinking water on resistance of biofilms to disinfection. Appl Environ Microbiol (2010) 0.92
2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms. Angew Chem Int Ed Engl (2012) 0.92
Inhibition of Staphylococcus epidermidis biofilm by trimethylsilane plasma coating. Antimicrob Agents Chemother (2012) 0.92
Bioactive coatings for orthopaedic implants-recent trends in development of implant coatings. Int J Mol Sci (2014) 0.91
Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study. PLoS One (2011) 0.91
Inhibition of biofilm formation, quorum sensing and infection in Pseudomonas aeruginosa by natural products-inspired organosulfur compounds. PLoS One (2012) 0.91
Effective removal of staphylococcal biofilms by the endolysin LysH5. PLoS One (2014) 0.90
Antimicrobial peptide GL13K is effective in reducing biofilms of Pseudomonas aeruginosa. Antimicrob Agents Chemother (2013) 0.90
Retracted Small protein-mediated quorum sensing in a Gram-negative bacterium. PLoS One (2011) 0.90
Fitness landscape of antibiotic tolerance in Pseudomonas aeruginosa biofilms. PLoS Pathog (2011) 0.90
Expression of the primary carbohydrate component of the Bordetella bronchiseptica biofilm matrix is dependent on growth phase but independent of Bvg regulation. J Bacteriol (2006) 0.89
Interspecific small molecule interactions between clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus from adult cystic fibrosis patients. PLoS One (2014) 0.89
Role of biofilm in children with recurrent upper respiratory tract infections. Eur J Clin Microbiol Infect Dis (2014) 0.89
Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics. Mol Syst Biol (2015) 0.89
Multiphase flow models of biogels from crawling cells to bacterial biofilms. HFSP J (2010) 0.88
Mini-review: Lactoferrin: a bioinspired, anti-biofilm therapeutic. Biofouling (2013) 0.88
Potential antibacterial activity of carvacrol-loaded poly(DL-lactide-co-glycolide) (PLGA) nanoparticles against microbial biofilm. Int J Mol Sci (2011) 0.87
Silver-zinc redox-coupled electroceutical wound dressing disrupts bacterial biofilm. PLoS One (2015) 0.87
Magnetic nanoparticle targeted hyperthermia of cutaneous Staphylococcus aureus infection. Ann Biomed Eng (2012) 0.87
Efficacy of ethanol against Candida albicans and Staphylococcus aureus polymicrobial biofilms. Antimicrob Agents Chemother (2012) 0.87
Chitosan coupling makes microbial biofilms susceptible to antibiotics. Sci Rep (2013) 0.87
Eugenol: a phyto-compound effective against methicillin-resistant and methicillin-sensitive Staphylococcus aureus clinical strain biofilms. PLoS One (2015) 0.87