Published in J Immunol on February 15, 2003
Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J Exp Med (2009) 1.72
Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease. J Clin Invest (2004) 1.57
ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol (2011) 1.54
A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice. J Clin Invest (2004) 1.23
Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells. Eur J Immunol (2006) 1.16
Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression. Infect Immun (2005) 1.15
Strategies to alleviate original antigenic sin responses to influenza viruses. Proc Natl Acad Sci U S A (2012) 1.12
Commensal-epithelial signaling mediated via formyl peptide receptors. Am J Pathol (2010) 1.08
Role of dendritic cells in differential susceptibility to viral demyelinating disease. PLoS Pathog (2007) 1.04
Murine autoimmune hearing loss mediated by CD4+ T cells specific for inner ear peptides. J Clin Invest (2004) 1.03
Role of regulatory T cells in a new mouse model of experimental autoimmune myositis. Am J Pathol (2009) 0.95
Repetitive pertussis toxin promotes development of regulatory T cells and prevents central nervous system autoimmune disease. PLoS One (2010) 0.93
A single nucleotide polymorphism in Tyk2 controls susceptibility to experimental allergic encephalomyelitis. J Immunol (2009) 0.93
The immunodominant CD8+ T cell epitope region of Theiler's virus in resistant C57BL/6 mice is critical for anti-viral immune responses, viral persistence, and binding to the host cells. Virology (2006) 0.92
AB toxins: a paradigm switch from deadly to desirable. Toxins (Basel) (2010) 0.88
TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING. PLoS Pathog (2015) 0.86
Influence of pertussis toxin on CD1a isoform expression in human dendritic cells. J Clin Immunol (2006) 0.83
Signaling through Galphai2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. J Leukoc Biol (2007) 0.83
Mechanistic insight into pertussis toxin and lectin signaling using T cells engineered to express a CD8α/CD3ζ chimeric receptor. Biochemistry (2012) 0.81
Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin. J Cancer Res Clin Oncol (2011) 0.80
Differential levels of resistance to disease induction and development of relapsing experimental autoimmune encephalomyelitis in two H-2b-restricted mouse strains. J Neuroimmunol (2011) 0.80
Role of dendritic cell subsets in immunity and their contribution to noninfectious uveitis. Surv Ophthalmol (2015) 0.78
Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin. J Immunol (2011) 0.78
P2Y2R deficiency attenuates experimental autoimmune uveitis development. PLoS One (2015) 0.77
Histamine H₂ receptor signaling × environment interactions determine susceptibility to experimental allergic encephalomyelitis. FASEB J (2013) 0.76
Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis. J Immunol (2016) 0.75
Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science (2006) 6.06
Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science (2005) 3.80
MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol (2009) 3.48
Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell (2013) 3.32
A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription. Cell (2005) 3.22
Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Sci Transl Med (2011) 3.08
TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation. Nat Immunol (2008) 3.02
Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem (2002) 2.67
Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia. Cell (2005) 2.52
Early use of noninvasive positive pressure ventilation for acute lung injury: a multicenter randomized controlled trial. Crit Care Med (2012) 2.43
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol Cell (2004) 2.37
Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res (2008) 2.29
Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance. Nature (2009) 2.27
Novel as1 and as2 defects in leaf adaxial-abaxial polarity reveal the requirement for ASYMMETRIC LEAVES1 and 2 and ERECTA functions in specifying leaf adaxial identity. Development (2003) 2.17
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol (2005) 2.17
Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost (2002) 2.16
Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1. Nat Immunol (2007) 2.15
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer. J Clin Invest (2012) 2.12
Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation. Nat Med (2006) 2.11
Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1. J Cell Biochem (2006) 2.11
The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1. EMBO J (2010) 2.04
Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. J Clin Invest (2006) 2.02
E-cadherin-mediated cell-cell contact is critical for induced pluripotent stem cell generation. Stem Cells (2010) 1.97
The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry. Cell Host Microbe (2013) 1.86
An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells. Nat Immunol (2008) 1.79
WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation. J Biol Chem (2003) 1.79
Movin' on up: the role of PtdIns(4,5)P(2) in cell migration. Trends Cell Biol (2006) 1.72
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors. Immunity (2013) 1.69
Beta-arrestin signaling and regulation of transcription. J Cell Sci (2007) 1.62
High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections. Proc Natl Acad Sci U S A (2007) 1.62
Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity. PLoS One (2008) 1.59
A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. J Biol Chem (2002) 1.59
ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol (2011) 1.54
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 1.54
Spontaneous breathing with biphasic positive airway pressure attenuates lung injury in hydrochloric acid-induced acute respiratory distress syndrome. Anesthesiology (2014) 1.53
Concern Immune protection induced on day 10 following administration of the 2009 A/H1N1 pandemic influenza vaccine. PLoS One (2010) 1.51
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1. J Biol Chem (2003) 1.51
Multiplexed quantification of nucleic acids with large dynamic range using multivolume digital RT-PCR on a rotational SlipChip tested with HIV and hepatitis C viral load. J Am Chem Soc (2011) 1.51
Receptor tyrosine kinases positively regulate BACE activity and Amyloid-beta production through enhancing BACE internalization. Cell Res (2007) 1.50
Interferon-gamma Inhibits Melanogenesis and Induces Apoptosis in Melanocytes: A Pivotal Role of CD8+ Cytotoxic T Lymphocytes in Vitiligo. Acta Derm Venereol (2015) 1.48
Respiratory care practices and requirements for respiratory therapists in Beijing intensive care units. Respir Care (2011) 1.41
Outcomes in treatment for primary spinal anaplastic ependymomas: a retrospective series of 20 patients. J Neurosurg Spine (2013) 1.41
Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2. J Biol Chem (2002) 1.41
Unusual architecture of the p7 channel from hepatitis C virus. Nature (2013) 1.39
Transcriptional control of monocyte gene expression in post-traumatic stress disorder. Dis Markers (2011) 1.36
Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells. Dev Cell (2012) 1.35
Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction. Mol Cell (2011) 1.35
Higher intratumoral infiltrated Foxp3+ Treg numbers and Foxp3+/CD8+ ratio are associated with adverse prognosis in resectable gastric cancer. J Cancer Res Clin Oncol (2010) 1.34
Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage. J Leukoc Biol (2009) 1.34
Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection. AIDS (2010) 1.34
A multicenter application and evaluation of the oxford classification of IgA nephropathy in adult chinese patients. Am J Kidney Dis (2012) 1.32
A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family. Crit Rev Biochem Mol Biol (2007) 1.32
Invasive chronic inflammatory monocyte phenotype in subjects with high HIV-1 viral load. J Neuroimmunol (2004) 1.32
Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus. J Biol Chem (2003) 1.31
HBsAg inhibits TLR9-mediated activation and IFN-alpha production in plasmacytoid dendritic cells. Mol Immunol (2009) 1.31
Rapidly increasing rates of hip fracture in Beijing, China. J Bone Miner Res (2012) 1.30
Influenza A virus replication induces cell cycle arrest in G0/G1 phase. J Virol (2010) 1.30
PEDV ORF3 encodes an ion channel protein and regulates virus production. FEBS Lett (2012) 1.29
Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling. PLoS One (2010) 1.29
High prevalence of myopia and high myopia in 5060 Chinese university students in Shanghai. Invest Ophthalmol Vis Sci (2012) 1.28
A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis. Cell Res (2010) 1.27
Sugar is an endogenous cue for juvenile-to-adult phase transition in plants. Elife (2013) 1.27
Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients. J Mol Biol (2004) 1.26
Snail is critical for tumor growth and metastasis of ovarian carcinoma. Int J Cancer (2010) 1.26
The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus. J Gen Virol (2014) 1.26
Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. Aging Cell (2011) 1.26
IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population. PLoS One (2012) 1.25
Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors. Vaccine (2009) 1.24
Hippocampal long-term potentiation is reduced by chronic opiate treatment and can be restored by re-exposure to opiates. J Neurosci (2002) 1.23
Negative regulation of Toll-like receptor signaling pathway. Microbes Infect (2009) 1.22
High density lipoprotein uptake by scavenger receptor SR-BII. J Biol Chem (2004) 1.21
Requirement for the basic helix-loop-helix transcription factor Dec2 in initial TH2 lineage commitment. Nat Immunol (2009) 1.19
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Cyr61 induces IL-6 production by fibroblast-like synoviocytes promoting Th17 differentiation in rheumatoid arthritis. J Immunol (2012) 1.19
Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. J Immunol (2010) 1.19
The spike protein of severe acute respiratory syndrome (SARS) is cleaved in virus infected Vero-E6 cells. Cell Res (2004) 1.18
Modification of hippocampal neurogenesis and neuroplasticity by social environments. Exp Neurol (2003) 1.18
Inhibition of collagen-induced platelet aggregation by anopheline antiplatelet protein, a saliva protein from a malaria vector mosquito. Blood (2007) 1.16
Beta-arrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation. EMBO J (2005) 1.15
A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. Arthritis Rheumatol (2014) 1.14
Cilostazol as a unique antithrombotic agent. Curr Pharm Des (2003) 1.13
Modification of nonstructural protein 1 of influenza A virus by SUMO1. J Virol (2010) 1.13
Ethylene signaling and regulation in plant growth and stress responses. Plant Cell Rep (2013) 1.13
Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys. J Immunol (2006) 1.12
Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. J Virol (2008) 1.11
Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells. Cell Res (2008) 1.10
Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease. Curr Alzheimer Res (2009) 1.09
Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease. PLoS One (2009) 1.07
Heterologous prime/boost immunization of rhesus monkeys by using diverse poxvirus vectors. J Virol (2007) 1.07
Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study. Crit Care (2014) 1.07
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release. Proc Natl Acad Sci U S A (2006) 1.07