Published in Blood on February 13, 2003
Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. Mol Ther (2007) 1.76
An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation. Blood (2007) 1.57
Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element. Mol Ther (2009) 1.43
Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR. Mol Ther (2009) 1.22
Derivation of normal macrophages from human embryonic stem (hES) cells for applications in HIV gene therapy. Retrovirology (2006) 1.21
Genomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator. Mol Ther (2009) 1.13
The use of chromatin insulators to improve the expression and safety of integrating gene transfer vectors. Hum Gene Ther (2011) 1.11
Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells. J Virol (2005) 1.08
Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia. Stem Cell Res Ther (2011) 1.06
pTransgenesis: a cross-species, modular transgenesis resource. Development (2011) 0.99
G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia. Oncogene (2005) 0.98
The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery. Genet Vaccines Ther (2004) 0.97
Adoptive immunotherapy of disseminated leukemia with TCR-transduced, CD8+ T cells expressing a known endogenous TCR. Mol Ther (2009) 0.96
Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants. BMC Biotechnol (2009) 0.96
Bypass of senescence, immortalization, and transformation of human hematopoietic progenitor cells. Stem Cells (2005) 0.95
Gene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator. PLoS One (2009) 0.92
Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells. DNA Repair (Amst) (2007) 0.90
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res (2015) 0.89
Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development. Mol Ther (2006) 0.87
RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA? Expert Opin Biol Ther (2010) 0.87
Reducing the genotoxic potential of retroviral vectors. Methods Mol Biol (2008) 0.84
Factor VIII delivered by haematopoietic stem cell-derived B cells corrects the phenotype of haemophilia A mice. Thromb Haemost (2011) 0.82
The sea urchin sns5 insulator protects retroviral vectors from chromosomal position effects by maintaining active chromatin structure. Mol Ther (2009) 0.82
MePR: a novel human mesenchymal progenitor model with characteristics of pluripotency. Stem Cells Dev (2013) 0.81
S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection. Nucleic Acids Res (2014) 0.81
The GATA1-HS2 enhancer allows persistent and position-independent expression of a β-globin transgene. PLoS One (2011) 0.79
A chimeric HS4-SAR insulator (IS2) that prevents silencing and enhances expression of lentiviral vectors in pluripotent stem cells. PLoS One (2014) 0.78
Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells. Int J Med Sci (2015) 0.78
Hematopoietic stem cells. Methods Enzymol (2006) 0.78
Genomic cis-acting Sequences Improve Expression and Establishment of a Nonviral Vector. Mol Ther Nucleic Acids (2013) 0.78
Use of lentiviral vectors to deliver and express bicistronic transgenes in developing chicken embryos. Methods (2013) 0.78
Strategies to insulate lentiviral vector-expressed transgenes. Methods Mol Biol (2010) 0.77
Influence of insulators on transgene expression from integrating and non-integrating lentiviral vectors. Genet Vaccines Ther (2011) 0.77
Ex vivo transduction and transplantation of bone marrow cells for liver gene delivery of alpha1-antitrypsin. Mol Ther (2010) 0.76
Optimizing autologous cell grafts to improve stem cell gene therapy. Exp Hematol (2016) 0.76
An Erythroid-Specific Chromatin Opening Element Increases β-Globin Gene Expression from Integrated Retroviral Gene Transfer Vectors. Gene Ther Mol Biol (2004) 0.75
Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells. Sci Rep (2016) 0.75
Retroviral vectors encoding ADA regulatory locus control region provide enhanced T-cell-specific transgene expression. Genet Vaccines Ther (2009) 0.75
Feline immunodeficiency virus-mediated long-term transgene expression in undifferentiated retinal progenitor cells and its downregulation in differentiated cells. Mol Vis (2008) 0.75
Evidence for the in vivo safety of insulated foamy viral vectors. Gene Ther (2016) 0.75
Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature (2011) 3.56
Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions. Hum Gene Ther (2005) 3.49
High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors. Stem Cells (2003) 2.42
Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5. Blood (2002) 1.96
HOX and non-HOX homeobox genes in leukemic hematopoiesis. Stem Cells (2002) 1.94
Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. Mol Ther (2007) 1.76
Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24. Stem Cells (2007) 1.68
Does retroviral insertional mutagenesis play a role in the generation of induced pluripotent stem cells? Mol Ther (2008) 1.47
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling. Oncogene (2003) 1.28
Correction of murine hemophilia A by hematopoietic stem cell gene therapy. Mol Ther (2005) 1.25
Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells. Blood (2002) 1.25
Sustained phenotypic correction of hemophilia a mice following oncoretroviral-mediated expression of a bioengineered human factor VIII gene in long-term hematopoietic repopulating cells. Mol Ther (2004) 1.12
Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition. Mol Cell Biol (2004) 1.00
Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration. Blood (2002) 1.00
G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia. Oncogene (2005) 0.98
Flow cytometry of fluorescent proteins. Methods (2012) 0.97
Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1. Am J Hematol (2013) 0.96
TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage. Br J Haematol (2006) 0.96
BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation. J Biol Chem (2003) 0.96
Multiparameter flow cytometry of fluorescent protein reporters. Methods Mol Biol (2004) 0.95
Acetylation-dependent oncogenic activity of metastasis-associated protein 1 co-regulator. EMBO Rep (2010) 0.95
Bypass of senescence, immortalization, and transformation of human hematopoietic progenitor cells. Stem Cells (2005) 0.95
Specific homeodomain-DNA interactions are required for HOX11-mediated transformation. Blood (2003) 0.93
Overexpression of rab7 enhances the kinetics of antigen processing and presentation with MHC class II molecules in B cells. Int Immunol (2002) 0.92
Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A. Curr Gene Ther (2003) 0.90
Generation of HIV-1-based lentiviral vector particles. Curr Protoc Mol Biol (2002) 0.88
Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis. Br J Haematol (2009) 0.88
Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector. Mol Ther (2003) 0.88
Overview of the HIV-1 Lentiviral Vector System. Curr Protoc Mol Biol (2002) 0.88
Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development. Mol Ther (2006) 0.87
Immortalization of yolk sac-derived precursor cells. Blood (2002) 0.87
TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells. Mol Cancer (2010) 0.85
Resistance to fas-induced apoptosis in cells from human atherosclerotic lesions: elevated Bcl-XL inhibits apoptosis and caspase activation. J Vasc Res (2007) 0.85
Reducing the genotoxic potential of retroviral vectors. Methods Mol Biol (2008) 0.84
Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors. Biochem Biophys Res Commun (2009) 0.84
Genetic analysis of the ATG7 gene promoter in sporadic Parkinson's disease. Neurosci Lett (2013) 0.82
Factor VIII delivered by haematopoietic stem cell-derived B cells corrects the phenotype of haemophilia A mice. Thromb Haemost (2011) 0.82
Detection and enrichment of hematopoietic stem cells by side population phenotype. Methods Mol Biol (2004) 0.81
Analysis of violet-excited fluorochromes by flow cytometry using a violet laser diode. Cytometry A (2003) 0.81
Integrative molecular and developmental biology of adult stem cells. Biol Cell (2003) 0.80
Retroviral transduction in fetal thymic organ culture. Methods Mol Med (2005) 0.80
A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease. Neurosci Lett (2013) 0.80
Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. FASEB J (2005) 0.79
SCID repopulating cells derived from unmobilised adult human peripheral blood. Curr Med Res Opin (2004) 0.79
TLX1 (HOX11) immortalization of embryonic stem cell-derived and primary murine hematopoietic progenitors. Curr Protoc Stem Cell Biol (2008) 0.78
Hematopoietic stem cells. Methods Enzymol (2006) 0.78
Hematopoietic immortalizing function of the NKL-subclass homeobox gene TLX1. Genes Chromosomes Cancer (2010) 0.77
Tissue inhibitor of matrix metalloproteinase-1 overexpression in M1 myeloblasts impairs IL-6-induced differentiation. Oncogene (2004) 0.77
Lentiviral fluorescent protein expression vectors for biotinylation proteomics. Methods Mol Biol (2011) 0.77
Strategies to insulate lentiviral vector-expressed transgenes. Methods Mol Biol (2010) 0.77
Apoptotic role of IKK in T-ALL therapeutic response. Mol Cancer Res (2011) 0.76
Human immunodeficiency virus type 1-based vectors for gene delivery to human hematopoietic stem cells. Methods Mol Med (2003) 0.76
Editorial retraction. Stem Cells (2006) 0.75
New feature: stem cells in the news. Stem Cells (2002) 0.75
The tao of hematopoietic stem cells: toward a unified theory of tissue regeneration. ScientificWorldJournal (2002) 0.75
Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication. Stem Cells (2005) 0.75
Somatic stem cell plasticity: to be or not to be. Stem Cells (2002) 0.75
Stem cell bouillabaisse-potpourri. Stem Cells (2002) 0.75
Identification of a novel 21bp-insertion variant within the LC3B gene promoter in sporadic Parkinson's disease. Transl Res (2013) 0.75