Published in Stem Cells on January 01, 2002
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A (2004) 28.29
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization. Mol Cell Biol (2004) 3.62
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood (2005) 2.99
Embryonic stem cell-derived hematopoietic stem cells. Proc Natl Acad Sci U S A (2005) 2.28
A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster. Blood (2009) 2.18
GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis. Cancer Cell (2010) 1.57
Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A (2007) 1.31
Cancer-associated genomic regions (CAGRs) and noncoding RNAs: bioinformatics and therapeutic implications. Mamm Genome (2008) 1.23
HOX proteins and leukemia. Int J Clin Exp Pathol (2008) 1.14
Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: a meta-analysis. PLoS One (2012) 1.12
Thrombopoietin induces HOXA9 nuclear transport in immature hematopoietic cells: potential mechanism by which the hormone favorably affects hematopoietic stem cells. Mol Cell Biol (2004) 1.12
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cells. PLoS One (2006) 1.09
G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia. Oncogene (2005) 0.98
TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage. Br J Haematol (2006) 0.96
Hox genes and their candidate downstream targets in the developing central nervous system. Cell Mol Neurobiol (2005) 0.94
Msx and dlx homeogene expression in epithelial odontogenic tumors. J Histochem Cytochem (2008) 0.93
The preleukemic state of mice reconstituted with Mixl1-transduced marrow cells. Proc Natl Acad Sci U S A (2007) 0.93
Enforced expression of the homeobox gene Mixl1 impairs hematopoietic differentiation and results in acute myeloid leukemia. Proc Natl Acad Sci U S A (2006) 0.93
Nup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis. Mol Biol Cell (2010) 0.92
TLX1/HOX11-induced hematopoietic differentiation blockade. Oncogene (2007) 0.91
Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis. Blood (2012) 0.89
A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a. PLoS One (2009) 0.88
HOXB5 expression in oral squamous cell carcinoma. J Appl Oral Sci (2011) 0.85
TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells. Mol Cancer (2010) 0.85
Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells. Int J Dev Biol (2010) 0.83
Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo. Blood (2014) 0.83
Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer. Cancers (Basel) (2011) 0.81
Challenges and opportunities in targeting the menin-MLL interaction. Future Med Chem (2014) 0.79
A reverse transcriptase-dependent mechanism is essential for murine preimplantation development. Genes (Basel) (2011) 0.78
Lentiviral fluorescent protein expression vectors for biotinylation proteomics. Methods Mol Biol (2011) 0.77
Hematopoietic immortalizing function of the NKL-subclass homeobox gene TLX1. Genes Chromosomes Cancer (2010) 0.77
Phosphorylation of HOX11/TLX1 on Threonine-247 during mitosis modulates expression of cyclin B1. Mol Cancer (2010) 0.75
PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity. Mol Cell (2016) 0.75
The DN2 Myeloid-T (DN2mt) Progenitor is a Target Cell for Leukemic Transformation by the TLX1 Oncogene. J Bone Marrow Res (2013) 0.75
HOXC6 Overexpression Is Associated With Ki-67 Expression and Poor Survival in NPC Patients. J Cancer (2017) 0.75
Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions. Hum Gene Ther (2005) 3.49
High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors. Stem Cells (2003) 2.42
Functional analysis of various promoters in lentiviral vectors at different stages of in vitro differentiation of mouse embryonic stem cells. Mol Ther (2007) 1.76
Does retroviral insertional mutagenesis play a role in the generation of induced pluripotent stem cells? Mol Ther (2008) 1.47
Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator. Blood (2003) 1.40
Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling. Oncogene (2003) 1.28
Correction of murine hemophilia A by hematopoietic stem cell gene therapy. Mol Ther (2005) 1.25
Sustained phenotypic correction of hemophilia a mice following oncoretroviral-mediated expression of a bioengineered human factor VIII gene in long-term hematopoietic repopulating cells. Mol Ther (2004) 1.12
Role of the docking protein Gab2 in beta(1)-integrin signaling pathway-mediated hematopoietic cell adhesion and migration. Blood (2002) 1.00
Hematopoietic cell fate and the initiation of leukemic properties in primitive primary human cells are influenced by Ras activity and farnesyltransferase inhibition. Mol Cell Biol (2004) 1.00
G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia. Oncogene (2005) 0.98
Flow cytometry of fluorescent proteins. Methods (2012) 0.97
Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1. Am J Hematol (2013) 0.96
TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage. Br J Haematol (2006) 0.96
BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation. J Biol Chem (2003) 0.96
Multiparameter flow cytometry of fluorescent protein reporters. Methods Mol Biol (2004) 0.95
Acetylation-dependent oncogenic activity of metastasis-associated protein 1 co-regulator. EMBO Rep (2010) 0.95
Bypass of senescence, immortalization, and transformation of human hematopoietic progenitor cells. Stem Cells (2005) 0.95
Specific homeodomain-DNA interactions are required for HOX11-mediated transformation. Blood (2003) 0.93
Overexpression of rab7 enhances the kinetics of antigen processing and presentation with MHC class II molecules in B cells. Int Immunol (2002) 0.92
Development of improved factor VIII molecules and new gene transfer approaches for hemophilia A. Curr Gene Ther (2003) 0.90
Phenotype correction of Fanconi anemia group A hematopoietic stem cells using lentiviral vector. Mol Ther (2003) 0.88
Overview of the HIV-1 Lentiviral Vector System. Curr Protoc Mol Biol (2002) 0.88
Generation of HIV-1-based lentiviral vector particles. Curr Protoc Mol Biol (2002) 0.88
Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis. Br J Haematol (2009) 0.88
Stable gammaretroviral vector expression during embryonic stem cell-derived in vitro hematopoietic development. Mol Ther (2006) 0.87
Immortalization of yolk sac-derived precursor cells. Blood (2002) 0.87
TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells. Mol Cancer (2010) 0.85
Resistance to fas-induced apoptosis in cells from human atherosclerotic lesions: elevated Bcl-XL inhibits apoptosis and caspase activation. J Vasc Res (2007) 0.85
Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors. Biochem Biophys Res Commun (2009) 0.84
Reducing the genotoxic potential of retroviral vectors. Methods Mol Biol (2008) 0.84
Factor VIII delivered by haematopoietic stem cell-derived B cells corrects the phenotype of haemophilia A mice. Thromb Haemost (2011) 0.82
Genetic analysis of the ATG7 gene promoter in sporadic Parkinson's disease. Neurosci Lett (2013) 0.82
Analysis of violet-excited fluorochromes by flow cytometry using a violet laser diode. Cytometry A (2003) 0.81
Detection and enrichment of hematopoietic stem cells by side population phenotype. Methods Mol Biol (2004) 0.81
A novel and functional variant within the ATG5 gene promoter in sporadic Parkinson's disease. Neurosci Lett (2013) 0.80
Integrative molecular and developmental biology of adult stem cells. Biol Cell (2003) 0.80
Retroviral transduction in fetal thymic organ culture. Methods Mol Med (2005) 0.80
Specific pharmacological dimerization of KDR in lentivirally transduced human hematopoietic cells activates anti-apoptotic and proliferative mechanisms. FASEB J (2005) 0.79
SCID repopulating cells derived from unmobilised adult human peripheral blood. Curr Med Res Opin (2004) 0.79
Tissue inhibitor of matrix metalloproteinase-1 overexpression in M1 myeloblasts impairs IL-6-induced differentiation. Oncogene (2004) 0.77
Hematopoietic immortalizing function of the NKL-subclass homeobox gene TLX1. Genes Chromosomes Cancer (2010) 0.77
Lentiviral fluorescent protein expression vectors for biotinylation proteomics. Methods Mol Biol (2011) 0.77
Strategies to insulate lentiviral vector-expressed transgenes. Methods Mol Biol (2010) 0.77
Human immunodeficiency virus type 1-based vectors for gene delivery to human hematopoietic stem cells. Methods Mol Med (2003) 0.76
Apoptotic role of IKK in T-ALL therapeutic response. Mol Cancer Res (2011) 0.76
Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication. Stem Cells (2005) 0.75
Identification of a novel 21bp-insertion variant within the LC3B gene promoter in sporadic Parkinson's disease. Transl Res (2013) 0.75
Editorial retraction. Stem Cells (2006) 0.75
New feature: stem cells in the news. Stem Cells (2002) 0.75
The tao of hematopoietic stem cells: toward a unified theory of tissue regeneration. ScientificWorldJournal (2002) 0.75
Stem cell bouillabaisse-potpourri. Stem Cells (2002) 0.75
Somatic stem cell plasticity: to be or not to be. Stem Cells (2002) 0.75