Published in Arterioscler Thromb Vasc Biol on February 01, 2003
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood (2007) 2.83
The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation. Blood (2005) 1.21
PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling. Mol Cell Biol (2010) 1.14
PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate. Biochem J (2008) 1.11
CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding. Nucleic Acids Res (2009) 1.07
The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences. J Biol Chem (2006) 1.03
Molecular and developmental biology of the hemangioblast. Dev Dyn (2008) 0.99
The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors. Biochem J (2009) 0.92
The dual roles of homeobox genes in vascularization and wound healing. Cell Adh Migr (2012) 0.92
Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis. Front Pharmacol (2014) 0.85
The role of placental homeobox genes in human fetal growth restriction. J Pregnancy (2011) 0.77
Hhex Is Necessary for the Hepatic Differentiation of Mouse ES Cells and Acts via Vegf Signaling. PLoS One (2016) 0.75
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol (2007) 6.69
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
Identification and characterization of subpopulations in undifferentiated ES cell culture. Development (2008) 5.55
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell (2009) 5.19
Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem (2004) 3.73
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature (2010) 3.55
A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord. Nat Med (2006) 3.28
Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev (2002) 3.12
Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells. Cell Stem Cell (2010) 3.05
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Cell Stem Cell (2012) 3.03
Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem Biophys Res Commun (2006) 2.76
CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology. J Cell Biol (2008) 2.62
Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells. Mol Cell Biol (2006) 2.59
Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res (2002) 2.49
Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS One (2006) 2.46
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol Cell Biol (2003) 2.40
Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data. BMC Genomics (2008) 2.27
Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci U S A (2002) 2.27
Spinal dumbbell tumors: an analysis of a series of 118 cases. J Neurosurg Spine (2007) 2.13
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell (2008) 1.94
Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells. J Cell Sci (2007) 1.94
Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis. J Clin Invest (2004) 1.90
Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells. Mol Cell Biol (2003) 1.89
Thoracic myelopathy caused by ossification of the ligamentum flavum: clinical features and surgical results in the Japanese population. J Neurosurg Spine (2006) 1.88
A novel mechanism for regulating clonal propagation of mouse ES cells. Genes Cells (2004) 1.84
Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions. Arthritis Rheum (2005) 1.83
Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res (2002) 1.77
Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells (2003) 1.71
Retraction: Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature (2014) 1.62
Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development (2003) 1.62
Crowned Dens syndrome. J Bone Joint Surg Am (2007) 1.60
Hemostatic management of tooth extractions in patients on oral antithrombotic therapy. J Oral Maxillofac Surg (2008) 1.60
An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res (2005) 1.55
Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis. Blood (2009) 1.47
Therapeutic angiogenesis by implantation of a capillary structure constituted of human adipose tissue microvascular endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.46
Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells. BMC Dev Biol (2007) 1.45
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell (2007) 1.44
Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells. BMC Dev Biol (2008) 1.43
One-stage transfer of 2 paddles of thoracodorsal artery perforator flap with 1 pair of vascular anastomoses for Barraquer-Simons syndrome. J Craniofac Surg (2012) 1.41
Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells (2009) 1.39
Inhibition of DNA binding of Sox2 by the SUMO conjugation. Biochem Biophys Res Commun (2006) 1.38
Cut-offs for screening prolonged QT intervals from Fridericia's formula in children and adolescents. Circ J (2010) 1.38
Hemostatic management for periodontal treatments in patients on oral antithrombotic therapy: a retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.38
Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells. DNA Res (2008) 1.35
Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization. FASEB J (2006) 1.35
A comparison of the tube forming potentials of early and late endothelial progenitor cells. Exp Cell Res (2007) 1.32
Consequence of the loss of Sox2 in the developing brain of the mouse. FEBS Lett (2008) 1.26
Modulation of gene expression by human cytosolic tRNase Z(L) through 5'-half-tRNA. PLoS One (2009) 1.26
Nasotracheal intubation under curve-tipped suction catheter guidance reduces epistaxis. Can J Anaesth (2006) 1.25
Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis. Am J Pathol (2009) 1.24
Improved quantification of DNA methylation using methylation-sensitive restriction enzymes and real-time PCR. Epigenetics (2007) 1.21
Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol Cell Biol (2009) 1.20
Down syndrome candidate region 1,a downstream target of VEGF, participates in endothelial cell migration and angiogenesis. J Vasc Res (2004) 1.20
Molecular signatures of the three stem cell lineages in hydra and the emergence of stem cell function at the base of multicellularity. Mol Biol Evol (2012) 1.20
Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264. FEBS Lett (2002) 1.19
Effect of recombinant placental growth factor 2 on hypertension induced by full-length mouse soluble fms-like tyrosine kinase 1 adenoviral vector in pregnant mice. Hypertension (2009) 1.19
Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation. Dev Biol (2006) 1.19
In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade. Circulation (2004) 1.19
Oct-3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus. Mol Cell Biol (2005) 1.14
The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Mol Cell Biol (2004) 1.13
Retraction: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature (2014) 1.13
Functional analysis of histone methyltransferase g9a in B and T lymphocytes. J Immunol (2008) 1.12
DNA methylation is dispensable for the growth and survival of the extraembryonic lineages. Curr Biol (2010) 1.11
Isolation and characterization of vasohibin-2 as a homologue of VEGF-inducible endothelium-derived angiogenesis inhibitor vasohibin. Arterioscler Thromb Vasc Biol (2006) 1.11
Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Mol Cell (2013) 1.11
Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3. Stem Cells (2007) 1.11
Skeletal muscle metastasis secondary to cancer--a report of seven cases. Ups J Med Sci (2005) 1.09
Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells. Development (2010) 1.08
Courses of cervical disc herniation causing myelopathy or radiculopathy: an analysis based on computed tomographic discograms. Spine (Phila Pa 1976) (2003) 1.08
Gene regulation of a novel angiogenesis inhibitor, vasohibin, in endothelial cells. Biochem Biophys Res Commun (2005) 1.08
Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis. Am J Pathol (2010) 1.06
Results of surgical treatment for thoracic myelopathy: minimum 2-year follow-up study in 132 patients. J Neurosurg Spine (2007) 1.06
The MRI features and treatment of scapulothoracic bursitis: report of four cases. Ups J Med Sci (2004) 1.06
Vasohibin prevents arterial neointimal formation through angiogenesis inhibition. Biochem Biophys Res Commun (2006) 1.05
Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development (2014) 1.05
Regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes. J Biol Chem (2007) 1.04
Expression of vasohibin as a novel endothelium-derived angiogenesis inhibitor in endometrial cancer. Cancer Sci (2008) 1.04
Vasohibin-2 expressed in human serous ovarian adenocarcinoma accelerates tumor growth by promoting angiogenesis. Mol Cancer Res (2012) 1.03
Angiomyolipoma in the knee--a case report. Ups J Med Sci (2005) 1.02
Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun (2005) 1.02
Transcriptional regulation of human angiopoietin-2 by transcription factor Ets-1. Biochem Biophys Res Commun (2004) 1.02
Angiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1. PLoS One (2012) 1.02
All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling. Endocrinology (2006) 1.01
Gorham disease of the spine: a case report and treatment strategies for this enigmatic bone disease. Tohoku J Exp Med (2005) 1.00
Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis. Am J Physiol Renal Physiol (2011) 1.00
Myofibers express IL-6 after eccentric exercise. Am J Sports Med (2004) 1.00
Lunatic fringe potentiates Notch signaling in the developing brain. Mol Cell Neurosci (2010) 0.99
Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization. Am J Pathol (2004) 0.99
Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation. EMBO J (2011) 0.99