PubRank

Hitoshi Niwa

Author PubWeight™ 130.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 2007 6.69
2 Genome analysis of the platypus reveals unique signatures of evolution. Nature 2008 5.74
3 Identification and characterization of subpopulations in undifferentiated ES cell culture. Development 2008 5.55
4 The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell 2009 5.19
5 Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem 2004 3.73
6 Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev 2002 3.12
7 Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells. Cell Stem Cell 2010 3.05
8 Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Cell Stem Cell 2012 3.03
9 Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem Biophys Res Commun 2006 2.76
10 Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells. Mol Cell Biol 2006 2.59
11 Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res 2002 2.49
12 Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS One 2006 2.46
13 Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol Cell Biol 2003 2.40
14 Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data. BMC Genomics 2008 2.27
15 Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis. Proc Natl Acad Sci U S A 2002 2.27
16 Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell 2008 1.94
17 Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells. J Cell Sci 2007 1.94
18 Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells. Mol Cell Biol 2003 1.89
19 A novel mechanism for regulating clonal propagation of mouse ES cells. Genes Cells 2004 1.84
20 Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res 2002 1.77
21 Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells 2003 1.71
22 Retraction: Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature 2014 1.62
23 Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development 2003 1.62
24 Hemostatic management of tooth extractions in patients on oral antithrombotic therapy. J Oral Maxillofac Surg 2008 1.60
25 An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res 2005 1.55
26 Extra-embryonic endoderm cells derived from ES cells induced by GATA factors acquire the character of XEN cells. BMC Dev Biol 2007 1.45
27 Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades. Mol Biol Cell 2007 1.44
28 Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells. BMC Dev Biol 2008 1.43
29 Sall4 is essential for stabilization, but not for pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression. Stem Cells 2009 1.39
30 Inhibition of DNA binding of Sox2 by the SUMO conjugation. Biochem Biophys Res Commun 2006 1.38
31 Hemostatic management for periodontal treatments in patients on oral antithrombotic therapy: a retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009 1.38
32 Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells. DNA Res 2008 1.35
33 Consequence of the loss of Sox2 in the developing brain of the mouse. FEBS Lett 2008 1.26
34 Nasotracheal intubation under curve-tipped suction catheter guidance reduces epistaxis. Can J Anaesth 2006 1.25
35 Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol Cell Biol 2009 1.20
36 Molecular signatures of the three stem cell lineages in hydra and the emergence of stem cell function at the base of multicellularity. Mol Biol Evol 2012 1.20
37 Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264. FEBS Lett 2002 1.19
38 Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation. Dev Biol 2006 1.19
39 Oct-3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus. Mol Cell Biol 2005 1.14
40 The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Mol Cell Biol 2004 1.13
41 Retraction: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature 2014 1.13
42 DNA methylation is dispensable for the growth and survival of the extraembryonic lineages. Curr Biol 2010 1.11
43 Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Mol Cell 2013 1.11
44 Efficient derivation of embryonic stem cells by inhibition of glycogen synthase kinase-3. Stem Cells 2007 1.11
45 Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells. Development 2010 1.08
46 Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development 2014 1.05
47 Regulation of mesodermal differentiation of mouse embryonic stem cells by basement membranes. J Biol Chem 2007 1.04
48 Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun 2005 1.02
49 Lunatic fringe potentiates Notch signaling in the developing brain. Mol Cell Neurosci 2010 0.99
50 Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation. EMBO J 2011 0.99
51 Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells. Biochem Biophys Res Commun 2008 0.98
52 A new modification for safer submental orotracheal intubation. J Anesth 2011 0.96
53 Requirement of Oct3/4 function for germ cell specification. Dev Biol 2008 0.96
54 E-cadherin promotes incorporation of mouse epiblast stem cells into normal development. PLoS One 2012 0.94
55 Risk factors affecting postoperative hemorrhage after tooth extraction in patients receiving oral antithrombotic therapy. J Oral Maxillofac Surg 2011 0.94
56 HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro. Arterioscler Thromb Vasc Biol 2003 0.92
57 Wnt: what's needed to maintain pluripotency? Nat Cell Biol 2011 0.92
58 Risk factors affecting hemorrhage after tooth extraction in patients undergoing continuous infusion with unfractionated heparin. J Oral Maxillofac Surg 2011 0.92
59 Efficient conversion of ES cells into myogenic lineage using the gene-inducible system. Biochem Biophys Res Commun 2007 0.91
60 Hemodynamic and autonomic response to acute hemorrhage in streptozotocin-induced diabetic rats. Cardiovasc Diabetol 2010 0.90
61 Ca(2+)/calmodulin-protein kinase IIalpha in the trigeminal subnucleus caudalis contributes to neuropathic pain following inferior alveolar nerve transection. Exp Neurol 2005 0.89
62 Nonylphenol induces the death of neural stem cells due to activation of the caspase cascade and regulation of the cell cycle. J Neurochem 2004 0.89
63 PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis. Biochem Biophys Res Commun 2010 0.88
64 Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells. Development 2012 0.88
65 Disruption of the mouse protein Ser/Thr phosphatase 2Cbeta gene leads to early pre-implantation lethality. Mech Dev 2007 0.86
66 Anesthetic effects on susceptibility to cortical spreading depression. Neuropharmacology 2012 0.84
67 Drug-inducible gene recombination by the Dppa3-MER Cre MER transgene in the developmental cycle of the germ cell lineage in mice. Biol Reprod 2011 0.83
68 Diclofenac inhibits proliferation and differentiation of neural stem cells. Biochem Pharmacol 2003 0.82
69 Sema4D deficiency results in an increase in the number of oligodendrocytes in healthy and injured mouse brains. J Neurosci Res 2009 0.82
70 [Transcription factor network governing cellular pluripotency]. Rinsho Ketsueki 2009 0.82
71 RPAP3 splicing variant isoform 1 interacts with PIH1D1 to compose R2TP complex for cell survival. Biochem Biophys Res Commun 2012 0.81
72 Differential expression of mRNAs for PACAP and its receptors during neural differentiation of embryonic stem cells. Regul Pept 2005 0.81
73 Clonal expansion of human pluripotent stem cells on gelatin-coated surface. Biochem Biophys Res Commun 2010 0.81
74 Transcription factor network in embryonic stem cells: heterogeneity under the stringency. Biol Pharm Bull 2013 0.81
75 Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats. Int J Oral Sci 2012 0.80
76 Cough reflex under intravenous sedation during dental implant surgery is more frequent during procedures in the maxillary anterior region. J Oral Maxillofac Surg 2013 0.80
77 Influence of acute progressive hypoxia on cardiovascular variability in conscious spontaneously hypertensive rats. Auton Neurosci 2008 0.80
78 Kinetics of drug selection systems in mouse embryonic stem cells. BMC Biotechnol 2013 0.79
79 Genomic organization and promoter analysis of the Dnmt3b gene. Gene 2003 0.79
80 DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation. PLoS Genet 2013 0.79
81 Maintenance of pluripotency in mouse ES cells without Trp53. Sci Rep 2013 0.78
82 Small bolus of esmolol effectively prevents sodium nitroprusside-induced reflex tachycardia without adversely affecting blood pressure. J Oral Maxillofac Surg 2012 0.78
83 CrxOS maintains the self-renewal capacity of murine embryonic stem cells. Biochem Biophys Res Commun 2009 0.78
84 [Examination of the optimal midazolam dose required for loss of puncture memory at the time of spinal anesthesia]. Masui 2011 0.78
85 On the use of prothrombin complex concentrate in patients with coagulopathy requiring tooth extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010 0.78
86 Dental management prior to hematopoietic stem cell transplantation. Spec Care Dentist 2005 0.77
87 Hemostatic management during oral surgery in patients with a left-ventricular assist system undergoing high-level anticoagulant therapy: efficacy of low molecular weight heparin. J Oral Maxillofac Surg 2008 0.77
88 Immunohistochemical localization of SNARE proteins in dental pulp and periodontal ligament of the rat incisor. Anat Rec (Hoboken) 2010 0.77
89 A liaison between intrinsic and extrinsic regulators of pluripotency. EMBO J 2013 0.75
90 Stem cell systems in development of mammals. Dev Growth Differ 2010 0.75
91 Influence of acute hypoxia combined with nitrous oxide on cardiovascular variability in conscious hypertensive rats. Auton Neurosci 2010 0.75
92 Risk factors for hyperketonemia in cleft lip and palate infants during general anesthesia. J Oral Maxillofac Surg 2011 0.75
93 [Transcriptional network maintaining pluripotency of embryonic stem cells]. Tanpakushitsu Kakusan Koso 2008 0.75
94 [Case report of dentatorubral pallidoluysian atrophy in a patient on a ketogenic diet]. Masui 2009 0.75
95 Inferior alveolar nerve transection enhanced formalin-induced nocifensive responses in the upper lip: systemic buprenorphine had more antinociceptive efficacy over morphine. Pharmacology 2014 0.75
96 Fabrication of porous particulate for the scaffold by applying solution spraying method. Dent Mater J 2005 0.75
97 [Case of myotonic dystrophy eventually diagnosed by preoperative Allen's test]. Masui 2007 0.75
98 Limited mouth opening following induction of anesthesia in two patients with masticatory muscle tendon-aponeurosis hyperplasia. J Clin Anesth 2011 0.75
99 Considerations during intravenous sedation in geriatric dental patients with dementia. Clin Oral Investig 2014 0.75