Published in Mol Biol Cell on February 01, 2003
Membranes: a meeting point for lipids, proteins and therapies. J Cell Mol Med (2008) 1.37
The Hsp90 chaperone complex regulates GDI-dependent Rab recycling. Mol Biol Cell (2006) 1.09
Oxidative stress and inflammation: essential partners in alcoholic liver disease. Int J Hepatol (2012) 1.05
Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats. Cell Stress Chaperones (2006) 1.05
The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery? Br J Pharmacol (2011) 1.02
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience (2009) 1.02
Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-alpha regulation. J Leukoc Biol (2008) 0.98
Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice. Hepatology (2012) 0.91
Proteomic analysis of microtubule-associated proteins during macrophage activation. Mol Cell Proteomics (2009) 0.91
Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury. J Hepatol (2014) 0.87
Macrophages and bisphosphonate-related osteonecrosis of the jaw (BRONJ): evidence of local immunosuppression of macrophages in contrast to other infectious jaw diseases. Clin Oral Investig (2014) 0.86
Rescuing of deficient killing and phagocytic activities of macrophages derived from non-obese diabetic mice by treatment with geldanamycin or heat shock: potential clinical implications. Cell Stress Chaperones (2011) 0.78
HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo. PLoS One (2015) 0.78
Protective effect of exogenous 70-kDa heat shock protein during endotoxic shock (sepsis). Dokl Biol Sci (2007) 0.77
17-DMAG, an HSP90 Inhibitor, Ameliorates Multiple Organ Dysfunction Syndrome via Induction of HSP70 in Endotoxemic Rats. PLoS One (2016) 0.76
Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages. J Leukoc Biol (2017) 0.75
Effect of 70 kDa exogenous heat shock protein on biochemical parameters of Wistar rats in endotoxic shock. Dokl Biol Sci (2007) 0.75
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem (1983) 206.01
Functional rafts in cell membranes. Nature (1997) 38.89
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
Protein folding in the cell. Nature (1992) 19.60
Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell (1992) 17.81
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation. Proc Natl Acad Sci U S A (1994) 6.74
Epidemiology of sepsis: an update. Crit Care Med (2001) 5.16
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J (1992) 3.48
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity (1996) 3.33
Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90. J Biol Chem (2000) 3.06
Heat shock proteins: facts, thoughts, and dreams. Shock (1999) 2.91
Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. J Biol Chem (2001) 2.50
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease. Hum Mol Genet (2001) 2.29
Lateral diffusion of membrane-spanning and glycosylphosphatidylinositol-linked proteins: toward establishing rules governing the lateral mobility of membrane proteins. J Cell Biol (1991) 2.28
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. EMBO J (2002) 2.17
Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites. J Exp Med (1991) 2.10
Geldanamycin, a new antibiotic. J Antibiot (Tokyo) (1970) 2.04
Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J Biol Chem (1995) 2.02
Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J Immunol (2000) 1.94
Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J Biol Chem (1993) 1.93
The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains. J Biol Chem (1992) 1.85
p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2. J Biol Chem (1996) 1.70
Interactions between newly synthesized glycoproteins, calnexin and a network of resident chaperones in the endoplasmic reticulum. J Cell Biol (1997) 1.62
Regulation of NF-kappa B activity in murine macrophages: effect of bacterial lipopolysaccharide and phorbol ester. J Cell Physiol (1992) 1.41
Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide. Proc Natl Acad Sci U S A (1999) 1.40
Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96. Curr Opin Immunol (1998) 1.36
Geldanamycin, an hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway. J Cell Physiol (1998) 1.32
ATP and ADP modulate a cation channel formed by Hsc70 in acidic phospholipid membranes. J Biol Chem (2000) 1.28
Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70. Cell Stress Chaperones (2002) 1.27
HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells. J Exp Med (1992) 1.25
Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor. J Membr Biol (1990) 1.24
Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent. J Biol Chem (1997) 1.24
Several endoplasmic reticulum stress proteins, including ERp72, interact with thyroglobulin during its maturation. J Biol Chem (1994) 1.04
Signal transduction by GPI-anchored membrane proteins. Cell Biol Int Rep (1991) 1.03
Stabilization of protein synthesis in thermotolerant cells during heat shock. Association of heat shock protein-72 with ribosomal subunits of polysomes. J Biol Chem (1994) 1.03
Conformation-defective herpes simplex virus 1 glycoprotein B activates the promoter of the grp94 gene that codes for the 94-kD stress protein in the endoplasmic reticulum. DNA Cell Biol (1995) 1.01
Endotoxin receptors (CD14) are found with CD16 (Fc gamma RIII) in an intracellular compartment of neutrophils that contains alkaline phosphatase. J Immunol (1995) 0.94
Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis. Glycobiology (1999) 0.90
Geldanamycin inhibits NF-kappaB activation and interleukin-8 gene expression in cultured human respiratory epithelium. Am J Respir Cell Mol Biol (2001) 0.90
Association of Hsp47, Grp78, and Grp94 with procollagen supports the successive or coupled action of molecular chaperones. J Cell Biochem (1994) 0.85
Etiology of multiple organ failure. J Trauma (1990) 0.82
Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. J Immunol (2008) 1.95
Tumor-specific Hsp70 plasma membrane localization is enabled by the glycosphingolipid Gb3. PLoS One (2008) 1.30
Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70. Cell Stress Chaperones (2002) 1.27
Hsc70 and Hsp70 interact with phosphatidylserine on the surface of PC12 cells resulting in a decrease of viability. FASEB J (2004) 1.19
Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells. FASEB J (2009) 1.15
General anesthesia delays the inflammatory response and increases survival for mice with endotoxic shock. Clin Vaccine Immunol (2006) 1.15
Activation of toll-like receptor 4 is necessary for trauma hemorrhagic shock-induced gut injury and polymorphonuclear neutrophil priming. Shock (2012) 1.11
Genetic contribution to the septic response in a mouse model. Shock (2002) 1.08
Gender and age effects on outcome after pediatric traumatic brain injury. Pediatr Crit Care Med (2004) 1.08
Peritoneal acidosis mediates immunoprotection in laparoscopic surgery. Surgery (2007) 1.05
O-GlcNAc cycling enzymes associate with the translational machinery and modify core ribosomal proteins. Mol Biol Cell (2010) 1.05
A quantitative trait loci analysis to map genes involved in lipopolysaccharide-induced inflammatory response: identification of macrophage scavenger receptor 1 as a candidate gene. J Immunol (2006) 1.02
CO2 Pneumoperitoneum modifies the inflammatory response to sepsis. Ann Surg (2003) 0.95
Increase in phagocytosis after geldanamycin treatment or heat shock: role of heat shock proteins. J Immunol (2005) 0.91
Genetic background conditions the effect of sex steroids on the inflammatory response during endotoxic shock. Crit Care Med (2003) 0.90
Increased expression of CD14 in macrophages after inhibition of the cholesterol biosynthetic pathway by lovastatin. Mol Med (2007) 0.90
Age and caloric restriction diets are confounding factors that modify the response to lipopolysaccharide by peritoneal macrophages in C57BL/6 mice. Shock (2004) 0.89
The antifungal agent itraconazole induces the accumulation of high mannose glycoproteins in macrophages. J Biol Chem (2009) 0.88
Heat shock protein 70 binds its own messenger ribonucleic acid as part of a gene expression self-limiting mechanism. Cell Stress Chaperones (2006) 0.86
Period of irreversible therapeutic intervention during sepsis correlates with phase of innate immune dysfunction. J Biol Chem (2012) 0.86
A new feature of the stress response: increase in endocytosis mediated by Hsp70. Cell Stress Chaperones (2009) 0.85
Anesthesia-specific protection from endotoxic shock is not mediated through the vagus nerve. Surgery (2005) 0.85
An exaggerated inflammatory response after CLP correlates with a negative outcome. J Surg Res (2005) 0.85
Accelerated recovery after endotoxic challenge in heat shock-pretreated mice. Am J Physiol Regul Integr Comp Physiol (2002) 0.84
Vagal nerve stimulation blocks peritoneal macrophage inflammatory responsiveness after severe burn injury. Shock (2012) 0.84
Abdominal insufflation with CO2 causes peritoneal acidosis independent of systemic pH. J Gastrointest Surg (2005) 0.84
Itraconazole, a commonly used antifungal, inhibits Fcγ receptor-mediated phagocytosis: alteration of Fcγ receptor glycosylation and gene expression. Shock (2014) 0.83
IL-10 plasma levels are elevated after LPS injection in splenectomized A/J mice. J Surg Res (2005) 0.82
The severity of cholestatic injury is modulated by the genetic background. Shock (2005) 0.82
Interaction of heat shock protein 70 with membranes depends on the lipid environment. Cell Stress Chaperones (2014) 0.82
Acidification enhances peritoneal macrophage phagocytic activity. J Surg Res (2008) 0.81
Protection from lethal endotoxic shock after testosterone depletion is linked to chromosome X. Shock (2005) 0.81
Pulmonary preconditioning, injury, and inflammation modulate expression of the candidate tumor suppressor gene ECRG4 in lung. Exp Lung Res (2014) 0.80
Elevated expression of IL-23/IL-17 pathway-related mediators correlates with exacerbation of pulmonary inflammation during polymicrobial sepsis. Shock (2014) 0.80
HSP70 interacts with ribosomal subunits of thermotolerant cells. Shock (2003) 0.80
Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages. Innate Immun (2012) 0.79
Tumor necrosis factor expression is ameliorated after exposure to an acidic environment. J Surg Res (2010) 0.79
CO2 abdominal insufflation pretreatment increases survival after a lipopolysaccharide-contaminated laparotomy. J Gastrointest Surg (2006) 0.78
The combination of polymicrobial sepsis and endotoxin results in an inflammatory process that could not be predicted from the independent insults. J Surg Res (2003) 0.78
Enhanced LPS-induced TNF alpha production in heat-shocked human promonocytic cells: regulation at the translational/post-translational level. Biochim Biophys Acta (2005) 0.76
Acute acalculous cholecystitis-like phenotype in scavenger receptor A knock-out mice. J Surg Res (2011) 0.76
Sulfur amino acid metabolism limits the growth of children living in environments of poor sanitation. Med Hypotheses (2011) 0.76
Stress down south: meeting report of the fifth International Workshop on the Molecular Biology of Stress Responses. Cell Stress Chaperones (2006) 0.76
Carbon dioxide pneumoperitoneum-mediated attenuation of the inflammatory response is independent of systemic acidosis. Surgery (2005) 0.75
Dysfunction of the innate immune system during sepsis: a call for research. Crit Care Med (2013) 0.75
The transition from a rural to an urban environment alters expression of the human Ebola virus receptor Neiman-Pick C1: implications for the current epidemic in West Africa. Cell Stress Chaperones (2014) 0.75
The Molecular Complexity of Sepsis: Expression of Peroxisome Proliferator-Activated Receptor-α, the Tip of the Iceberg? Crit Care Med (2016) 0.75
Activation of the stress response in macrophages alters the M1/M2 balance by enhancing bacterial killing and IL-10 expression. J Mol Med (Berl) (2014) 0.75