Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
International network of cancer genome projects.
|
Nature
|
2010
|
20.35
|
2
|
Frequent pathway mutations of splicing machinery in myelodysplasia.
|
Nature
|
2011
|
11.44
|
3
|
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.
|
Cancer Res
|
2011
|
6.02
|
4
|
Extensive feature detection of N-terminal protein sorting signals.
|
Bioinformatics
|
2002
|
5.16
|
5
|
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.
|
Nat Genet
|
2012
|
4.84
|
6
|
Integrated molecular analysis of clear-cell renal cell carcinoma.
|
Nat Genet
|
2013
|
4.61
|
7
|
Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia.
|
N Engl J Med
|
2015
|
3.42
|
8
|
Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas.
|
Cancer Res
|
2011
|
2.81
|
9
|
Prediction of transcriptional terminators in Bacillus subtilis and related species.
|
PLoS Comput Biol
|
2005
|
2.54
|
10
|
Estimation of genetic networks and functional structures between genes by using Bayesian networks and nonparametric regression.
|
Pac Symp Biocomput
|
2002
|
2.30
|
11
|
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
|
Nat Genet
|
2013
|
2.14
|
12
|
Somatic SETBP1 mutations in myeloid malignancies.
|
Nat Genet
|
2013
|
2.12
|
13
|
Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
|
Nat Genet
|
2010
|
2.08
|
14
|
Inferring gene networks from time series microarray data using dynamic Bayesian networks.
|
Brief Bioinform
|
2003
|
2.08
|
15
|
Estimating gene networks from gene expression data by combining Bayesian network model with promoter element detection.
|
Bioinformatics
|
2003
|
1.95
|
16
|
Combining microarrays and biological knowledge for estimating gene networks via Bayesian networks.
|
Proc IEEE Comput Soc Bioinform Conf
|
2003
|
1.89
|
17
|
Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients.
|
Blood
|
2013
|
1.79
|
18
|
Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia.
|
Nat Genet
|
2013
|
1.71
|
19
|
Modeling gene expression regulatory networks with the sparse vector autoregressive model.
|
BMC Syst Biol
|
2007
|
1.69
|
20
|
The tumor-suppressive miR-497-195 cluster targets multiple cell-cycle regulators in hepatocellular carcinoma.
|
PLoS One
|
2013
|
1.69
|
21
|
ACTN1 mutations cause congenital macrothrombocytopenia.
|
Am J Hum Genet
|
2013
|
1.49
|
22
|
Dynamic Bayesian network and nonparametric regression for nonlinear modeling of gene networks from time series gene expression data.
|
Biosystems
|
2004
|
1.47
|
23
|
Bayesian network and nonparametric heteroscedastic regression for nonlinear modeling of genetic network.
|
J Bioinform Comput Biol
|
2003
|
1.44
|
24
|
A neural network method for identification of RNA-interacting residues in protein.
|
Genome Inform
|
2004
|
1.42
|
25
|
Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator.
|
FEBS Lett
|
2004
|
1.40
|
26
|
Inferring the global structure of chromosomes from structural variations.
|
BMC Genomics
|
2015
|
1.37
|
27
|
Biopathways representation and simulation on hybrid functional Petri net.
|
In Silico Biol
|
2003
|
1.37
|
28
|
Inferring gene regulatory networks from time-ordered gene expression data of Bacillus subtilis using differential equations.
|
Pac Symp Biocomput
|
2003
|
1.34
|
29
|
Statistical inference of transcriptional module-based gene networks from time course gene expression profiles by using state space models.
|
Bioinformatics
|
2008
|
1.33
|
30
|
The landscape of somatic mutations in Down syndrome-related myeloid disorders.
|
Nat Genet
|
2013
|
1.31
|
31
|
Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis.
|
Cancer Res
|
2013
|
1.29
|
32
|
Genomic Object Net: I. A platform for modelling and simulating biopathways.
|
Appl Bioinformatics
|
2003
|
1.26
|
33
|
A top-r feature selection algorithm for microarray gene expression data.
|
IEEE/ACM Trans Comput Biol Bioinform
|
2012
|
1.25
|
34
|
An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data.
|
Nucleic Acids Res
|
2013
|
1.24
|
35
|
Cell system ontology: representation for modeling, visualizing, and simulating biological pathways.
|
In Silico Biol
|
2007
|
1.20
|
36
|
BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders.
|
Blood
|
2013
|
1.16
|
37
|
Combining microarrays and biological knowledge for estimating gene networks via bayesian networks.
|
J Bioinform Comput Biol
|
2004
|
1.16
|
38
|
ClipCrop: a tool for detecting structural variations with single-base resolution using soft-clipping information.
|
BMC Bioinformatics
|
2011
|
1.15
|
39
|
Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria.
|
J Clin Invest
|
2014
|
1.09
|
40
|
Gene network inference and visualization tools for biologists: application to new human transcriptome datasets.
|
Nucleic Acids Res
|
2011
|
1.08
|
41
|
Recursive regularization for inferring gene networks from time-course gene expression profiles.
|
BMC Syst Biol
|
2009
|
1.06
|
42
|
Cell fate simulation model of gustatory neurons with MicroRNAs double-negative feedback loop by hybrid functional Petri net with extension.
|
Genome Inform
|
2006
|
1.04
|
43
|
Constructing biological pathway models with hybrid functional Petri nets.
|
In Silico Biol
|
2004
|
1.01
|
44
|
Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension.
|
BMC Syst Biol
|
2009
|
1.00
|
45
|
Kernel mixture survival models for identifying cancer subtypes, predicting patient's cancer types and survival probabilities.
|
Genome Inform
|
2004
|
1.00
|
46
|
Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages.
|
Cancer Res
|
2013
|
0.99
|
47
|
Modelling and simulation of signal transductions in an apoptosis pathway by using timed Petri nets.
|
J Biosci
|
2007
|
0.99
|
48
|
An efficient grid layout algorithm for biological networks utilizing various biological attributes.
|
BMC Bioinformatics
|
2007
|
0.99
|
49
|
Ontology-based instance data validation for high-quality curated biological pathways.
|
BMC Bioinformatics
|
2011
|
0.98
|
50
|
Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
|
Am J Hum Genet
|
2002
|
0.98
|
51
|
Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
|
J Hum Genet
|
2003
|
0.98
|
52
|
Estimating gene regulatory networks and protein-protein interactions of Saccharomyces cerevisiae from multiple genome-wide data.
|
Bioinformatics
|
2005
|
0.96
|
53
|
Online model checking approach based parameter estimation to a neuronal fate decision simulation model in Caenorhabditis elegans with hybrid functional Petri net with extension.
|
Mol Biosyst
|
2011
|
0.95
|
54
|
Epidermal growth factor receptor tyrosine kinase defines critical prognostic genes of stage I lung adenocarcinoma.
|
PLoS One
|
2012
|
0.95
|
55
|
Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism.
|
Am J Physiol Endocrinol Metab
|
2009
|
0.94
|
56
|
MIRACH: efficient model checker for quantitative biological pathway models.
|
Bioinformatics
|
2011
|
0.94
|
57
|
A versatile petri net based architecture for modeling and simulation of complex biological processes.
|
Genome Inform
|
2004
|
0.94
|
58
|
Cell Illustrator 4.0: a computational platform for systems biology.
|
In Silico Biol
|
2010
|
0.94
|
59
|
Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data.
|
Genome Inform
|
2006
|
0.93
|
60
|
A state space representation of VAR models with sparse learning for dynamic gene networks.
|
Genome Inform
|
2010
|
0.92
|
61
|
Genomic Object Net: II. Modelling biopathways by hybrid functional Petri net with extension.
|
Appl Bioinformatics
|
2003
|
0.91
|
62
|
Parameter estimation of in silico biological pathways with particle filtering towards a petascale computing.
|
Pac Symp Biocomput
|
2009
|
0.91
|
63
|
Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
|
J Hum Genet
|
2002
|
0.91
|
64
|
Automatic drawing of biological networks using cross cost and subcomponent data.
|
Genome Inform
|
2005
|
0.91
|
65
|
Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
|
Int J Oncol
|
2012
|
0.91
|
66
|
The rs6983267 SNP is associated with MYC transcription efficiency, which promotes progression and worsens prognosis of colorectal cancer.
|
Ann Surg Oncol
|
2012
|
0.90
|
67
|
A statistical framework for genome-wide discovery of biomarker splice variations with GeneChip Human Exon 1.0 ST Arrays.
|
Genome Inform
|
2006
|
0.89
|
68
|
Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling.
|
PLoS One
|
2010
|
0.89
|
69
|
Inferring dynamic gene networks under varying conditions for transcriptomic network comparison.
|
Bioinformatics
|
2010
|
0.89
|
70
|
Understanding endothelial cell apoptosis: what can the transcriptome, glycome and proteome reveal?
|
Philos Trans R Soc Lond B Biol Sci
|
2007
|
0.89
|
71
|
AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction.
|
BMC Bioinformatics
|
2007
|
0.88
|
72
|
Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.
|
Br J Haematol
|
2014
|
0.88
|
73
|
Comparing Pearson, Spearman and Hoeffding's D measure for gene expression association analysis.
|
J Bioinform Comput Biol
|
2009
|
0.88
|
74
|
Analysis of PPARalpha-dependent and PPARalpha-independent transcript regulation following fenofibrate treatment of human endothelial cells.
|
Angiogenesis
|
2009
|
0.88
|
75
|
Cell cycle gene networks are associated with melanoma prognosis.
|
PLoS One
|
2012
|
0.88
|
76
|
Estimating genome-wide gene networks using nonparametric Bayesian network models on massively parallel computers.
|
IEEE/ACM Trans Comput Biol Bioinform
|
2011
|
0.88
|
77
|
Fast grid layout algorithm for biological networks with sweep calculation.
|
Bioinformatics
|
2008
|
0.88
|
78
|
DA 1.0: parameter estimation of biological pathways using data assimilation approach.
|
Bioinformatics
|
2010
|
0.88
|
79
|
Computational strategy for discovering druggable gene networks from genome-wide RNA expression profiles.
|
Pac Symp Biocomput
|
2006
|
0.88
|
80
|
A novel network profiling analysis reveals system changes in epithelial-mesenchymal transition.
|
PLoS One
|
2011
|
0.88
|
81
|
N-cadherin expression is a potential survival mechanism of gefitinib-resistant lung cancer cells.
|
Am J Cancer Res
|
2011
|
0.88
|
82
|
Genomic data assimilation for estimating hybrid functional Petri net from time-course gene expression data.
|
Genome Inform
|
2006
|
0.88
|
83
|
Contribution of comparative fish studies to general endocrinology: structure and function of some osmoregulatory hormones.
|
J Exp Zool A Comp Exp Biol
|
2006
|
0.87
|
84
|
Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations.
|
Haematologica
|
2013
|
0.87
|
85
|
Identifying drug active pathways from gene networks estimated by gene expression data.
|
Genome Inform
|
2005
|
0.86
|
86
|
Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
|
Nat Commun
|
2013
|
0.86
|
87
|
A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development.
|
BMC Genomics
|
2012
|
0.86
|
88
|
Bayesian network and nonparametric heteroscedastic regression for nonlinear modeling of genetic network.
|
Proc IEEE Comput Soc Bioinform Conf
|
2002
|
0.86
|
89
|
Modeling nonlinear gene regulatory networks from time series gene expression data.
|
J Bioinform Comput Biol
|
2008
|
0.86
|
90
|
Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model.
|
BMC Genomics
|
2009
|
0.85
|
91
|
Weighted lasso in graphical Gaussian modeling for large gene network estimation based on microarray data.
|
Genome Inform
|
2007
|
0.85
|
92
|
Conversion from BioPAX to CSO for system dynamics and visualization of biological pathway.
|
Genome Inform
|
2007
|
0.85
|
93
|
Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing.
|
Int J Hematol
|
2008
|
0.85
|
94
|
Structural modeling and analysis of signaling pathways based on Petri nets.
|
J Bioinform Comput Biol
|
2006
|
0.85
|
95
|
Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates.
|
BMC Syst Biol
|
2008
|
0.85
|
96
|
ArrayCluster: an analytic tool for clustering, data visualization and module finder on gene expression profiles.
|
Bioinformatics
|
2006
|
0.84
|
97
|
BFL: a node and edge betweenness based fast layout algorithm for large scale networks.
|
BMC Bioinformatics
|
2009
|
0.84
|
98
|
Enhancement of collective immunity in Tokyo metropolitan area by selective vaccination against an emerging influenza pandemic.
|
PLoS One
|
2013
|
0.84
|
99
|
A novel meta-analysis approach of cancer transcriptomes reveals prevailing transcriptional networks in cancer cells.
|
Genome Inform
|
2010
|
0.83
|
100
|
The GC and window-averaged DNA curvature profile of secondary metabolite gene cluster in Aspergillus fumigatus genome.
|
Appl Microbiol Biotechnol
|
2008
|
0.83
|
101
|
A strategy to select suitable physicochemical attributes of amino acids for protein fold recognition.
|
BMC Bioinformatics
|
2013
|
0.83
|
102
|
Boundary formation by notch signaling in Drosophila multicellular systems: experimental observations and gene network modeling by Genomic Object Net.
|
Pac Symp Biocomput
|
2003
|
0.83
|
103
|
Sign: large-scale gene network estimation environment for high performance computing.
|
Genome Inform
|
2011
|
0.83
|
104
|
Predicting differences in gene regulatory systems by state space models.
|
Genome Inform
|
2008
|
0.82
|
105
|
CSO validator: improving manual curation workflow for biological pathways.
|
Bioinformatics
|
2011
|
0.82
|
106
|
ExonMiner: Web service for analysis of GeneChip Exon array data.
|
BMC Bioinformatics
|
2008
|
0.82
|
107
|
Extension and verification of the SEIR model on the 2009 influenza A (H1N1) pandemic in Japan.
|
Math Biosci
|
2013
|
0.82
|
108
|
A new regulatory interaction suggested by simulations for circadian genetic control mechanism in mammals.
|
J Bioinform Comput Biol
|
2006
|
0.82
|
109
|
Bayesian learning of biological pathways on genomic data assimilation.
|
Bioinformatics
|
2008
|
0.82
|
110
|
Use of gene networks from full genome microarray libraries to identify functionally relevant drug-affected genes and gene regulation cascades.
|
DNA Res
|
2003
|
0.82
|
111
|
Rule-based reasoning for system dynamics in cell systems.
|
Genome Inform
|
2008
|
0.81
|
112
|
The impact of measurement errors in the identification of regulatory networks.
|
BMC Bioinformatics
|
2009
|
0.81
|
113
|
Twist2 functions as a tumor suppressor in murine osteosarcoma cells.
|
Cancer Sci
|
2013
|
0.81
|
114
|
Systematic reconstruction of TRANSPATH data into cell system markup language.
|
BMC Syst Biol
|
2008
|
0.80
|
115
|
Cell illustrator 4.0: a computational platform for systems biology.
|
Stud Health Technol Inform
|
2011
|
0.80
|
116
|
A novel strategy to search conserved transcription factor binding sites among coexpressing genes in human.
|
Genome Inform
|
2008
|
0.80
|
117
|
Loss of CDCP1 expression promotes invasiveness and poor prognosis in esophageal squamous cell carcinoma.
|
Ann Surg Oncol
|
2014
|
0.80
|
118
|
PRD: A protein-RNA interaction database.
|
Bioinformation
|
2012
|
0.80
|
119
|
Use of gene networks for identifying and validating drug targets.
|
J Bioinform Comput Biol
|
2003
|
0.80
|
120
|
Computational gene network analysis reveals TNF-induced angiogenesis.
|
BMC Syst Biol
|
2012
|
0.80
|
121
|
Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine.
|
J Gastroenterol
|
2009
|
0.80
|
122
|
Characterization of T-cell Receptor Repertoire in Inflamed Tissues of Patients with Crohn's Disease Through Deep Sequencing.
|
Inflamm Bowel Dis
|
2016
|
0.80
|
123
|
Sparse overlapping group lasso for integrative multi-omics analysis.
|
J Comput Biol
|
2015
|
0.79
|
124
|
Statistical model-based testing to evaluate the recurrence of genomic aberrations.
|
Bioinformatics
|
2012
|
0.79
|
125
|
Simulation-based validation of the p53 transcriptional activity with hybrid functional petri net.
|
In Silico Biol
|
2006
|
0.79
|
126
|
A string pattern regression algorithm and its application to pattern discovery in long introns.
|
Genome Inform
|
2002
|
0.79
|
127
|
Identifying regulational alterations in gene regulatory networks by state space representation of vector autoregressive models and variational annealing.
|
BMC Genomics
|
2012
|
0.79
|
128
|
XiP: a computational environment to create, extend and share workflows.
|
Bioinformatics
|
2012
|
0.79
|
129
|
Utilizing evolutionary information and gene expression data for estimating gene networks with bayesian network models.
|
J Bioinform Comput Biol
|
2005
|
0.79
|
130
|
Unraveling dynamic activities of autocrine pathways that control drug-response transcriptome networks.
|
Pac Symp Biocomput
|
2009
|
0.79
|
131
|
Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
|
J Hum Genet
|
2004
|
0.79
|
132
|
Somatic mosaicism for a NRAS mutation associates with disparate clinical features in RAS-associated leukoproliferative disease: a report of two cases.
|
J Clin Immunol
|
2015
|
0.79
|
133
|
Quality control and reproducibility in DNA microarray experiments.
|
Genome Inform
|
2009
|
0.78
|
134
|
Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
|
Ann Surg Oncol
|
2014
|
0.78
|
135
|
Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.
|
Hum Mol Genet
|
2013
|
0.78
|
136
|
Tracing the development of acute myeloid leukemia in CBL syndrome.
|
Blood
|
2014
|
0.78
|
137
|
Multi-omics approach for estimating metabolic networks using low-order partial correlations.
|
J Comput Biol
|
2013
|
0.78
|
138
|
Vasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysis.
|
BMC Genomics
|
2013
|
0.78
|
139
|
A rank-based statistical test for measuring synergistic effects between two gene sets.
|
Bioinformatics
|
2011
|
0.78
|
140
|
Efficiently finding regulatory elements using correlation with gene expression.
|
J Bioinform Comput Biol
|
2004
|
0.78
|
141
|
A between-class overlapping filter-based method for transcriptome data analysis.
|
J Bioinform Comput Biol
|
2012
|
0.77
|
142
|
Gene regulatory network clustering for graph layout based on microarray gene expression data.
|
Genome Inform
|
2010
|
0.77
|
143
|
Comparison of gene expression profiles produced by CAGE, illumina microarray and real time RT-PCR.
|
Genome Inform
|
2010
|
0.77
|
144
|
Identification of activated transcription factors from microarray gene expression data of Kampo medicine-treated mice.
|
Genome Inform
|
2007
|
0.77
|
145
|
Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
|
Nat Genet
|
2016
|
0.77
|
146
|
Systems biology model repository for macrophage pathway simulation.
|
Bioinformatics
|
2011
|
0.77
|
147
|
A fast and robust statistical test based on likelihood ratio with Bartlett correction to identify Granger causality between gene sets.
|
Bioinformatics
|
2010
|
0.77
|
148
|
An efficient data assimilation schema for restoration and extension of gene regulatory networks using time-course observation data.
|
J Comput Biol
|
2014
|
0.77
|
149
|
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location information.
|
BMC Bioinformatics
|
2010
|
0.77
|
150
|
Estimation of nonlinear gene regulatory networks via L1 regularized NVAR from time series gene expression data.
|
Genome Inform
|
2008
|
0.77
|
151
|
Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q24.
|
Ann Surg Oncol
|
2012
|
0.76
|
152
|
MRG-binding protein contributes to colorectal cancer development.
|
Cancer Sci
|
2011
|
0.76
|
153
|
A female patient with incomplete hemophagocytic lymphohistiocytosis caused by a heterozygous XIAP mutation associated with non-random X-chromosome inactivation skewed towards the wild-type XIAP allele.
|
J Clin Immunol
|
2015
|
0.76
|
154
|
SiGN-SSM: open source parallel software for estimating gene networks with state space models.
|
Bioinformatics
|
2011
|
0.76
|
155
|
Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient.
|
Int J Hematol
|
2014
|
0.76
|
156
|
Simulation-Based Validation of the p53 Transcriptional Activity with Hybrid Functional Petri Net.
|
Stud Health Technol Inform
|
2011
|
0.76
|
157
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Performance improvement in protein N-myristoyl classification by BONSAI with insignificant indexing symbol.
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