Published in J Am Chem Soc on March 05, 2003
Ynamides: a modern functional group for the new millennium. Chem Rev (2010) 1.77
Synthesis of highly substituted indolines and indoles via intramolecular [4 + 2] cycloaddition of ynamides and conjugated enynes. J Am Chem Soc (2005) 1.45
Copper-mediated N-alkynylation of carbamates, ureas, and sulfonamides. A general method for the synthesis of ynamides. Org Lett (2003) 1.28
A unique approach to aldol products for the creation of all-carbon quaternary stereocentres. Nat Chem (2009) 1.20
Diamine Ligands in Copper-Catalyzed Reactions. Chem Sci (2010) 1.15
Direct palladium-catalyzed alkynylation of N-fused heterocycles. J Am Chem Soc (2007) 1.04
Synthesis of polycyclic benzofused nitrogen heterocycles via a tandem ynamide benzannulation/ring-closing metathesis strategy. Application in a formal total synthesis of (+)-FR900482. J Org Chem (2011) 0.97
SYNTHESIS OF YNAMIDES BY N-ALKYNYLATION OF AMINE DERIVATIVES. PREPARATION OF N-ALLYL-N-(METHOXYCARBONYL)-1,3-DECADIYNYLAMINE. Organic Synth (2007) 0.94
Synthesis of alpha-keto-imides via oxidation of ynamides. J Org Chem (2008) 0.93
[2+2] Cycloaddition of ketenes with ynamides. A general method for the synthesis of 3-aminocyclobutenone derivatives. Tetrahedron (2006) 0.93
A sequential metal-catalyzed C-N bond formation in the synthesis of 2-amido-indoles. Org Lett (2008) 0.89
Fast and highly chemoselective alkynylation of thiols with hypervalent iodine reagents enabled through a low energy barrier concerted mechanism. J Am Chem Soc (2014) 0.88
Benzannulation via the reaction of ynamides and vinylketenes. application to the synthesis of highly substituted indoles. J Org Chem (2013) 0.83
A highly stereoselective addition of lithiated ynamides to Ellman-Davis chiral N-tert-butanesulfinyl imines. Org Lett (2013) 0.82
A Rhodium(I)-Xylyl-BINAP Catalyzed Asymmetric Ynamide-[2 + 2 + 2] Cycloaddition in the Synthesis of Optically Enriched N,O-Biaryls. Tetrahedron (2009) 0.82
Copper(I)-catalyzed nucleophilic addition of ynamides to acyl chlorides and activated N-heterocycles. J Org Chem (2014) 0.81
Saucy-Marbet Rearrangements of Alkynyl Halides in the Synthesis of Highly Enantiomerically Enriched Allenyl Halides. Tetrahedron Lett (2008) 0.80
A Stereoselective Intramolecular Cyclopropanation via a De Novo Class of Push-Pull Carbenes Derived from DMDO-Epoxidations of Chiral Ynamides. New J Chem (2010) 0.80
Efficient Access to Multifunctional Trifluoromethyl Alcohols through Base-Free Catalytic Asymmetric C-C Bond Formation with Terminal Ynamides. Angew Chem Int Ed Engl (2016) 0.79
A Convenient Synthesis of γ-Amino-Ynamides via Additions of Lithiated Ynamides to Aryl Imines. Observation of an Aza-Meyer-Schuster Rearrangement. Synthesis (Stuttg) (2013) 0.78
SYNTHESIS OF DE NOVO CHIRAL γ-AMINO-YNAMIDES USING LITHIATED YNAMIDES. OBSERVATION OF A UNIQUE 5-ENDO-DIG CYCLIZATION WITH AN INVERSION OF S-CENTER. Heterocycles (2014) 0.78
S3S63 Terminal Ynamides: Synthesis, Coupling Reactions and Additions to Common Electrophiles. Tetrahedron Lett (2015) 0.78
Batch and flow photochemical benzannulations based on the reaction of ynamides and diazo ketones. Application to the synthesis of polycyclic aromatic and heteroaromatic compounds. J Org Chem (2013) 0.76
A Silver(I)-Catalyzed Intramolecular Ficini's [2 + 2] Cycloaddition Employing Ynamides. Tetrahedron Lett (2015) 0.75
Ynamide carbopalladation: a flexible route to mono-, bi- and tricyclic azacycles. Chemistry (2015) 0.75
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst (2008) 11.93
COORDINATE DESCENT ALGORITHMS FOR NONCONVEX PENALIZED REGRESSION, WITH APPLICATIONS TO BIOLOGICAL FEATURE SELECTION. Ann Appl Stat (2011) 4.18
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc Natl Acad Sci U S A (2006) 4.16
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell (2011) 3.27
Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. J Clin Oncol (2010) 2.93
Regulation of gene expression in the mammalian eye and its relevance to eye disease. Proc Natl Acad Sci U S A (2006) 2.91
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα. Cell (2013) 2.87
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res (2013) 2.63
Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair. Genes Dev (2005) 2.47
Regularized ROC method for disease classification and biomarker selection with microarray data. Bioinformatics (2005) 2.38
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data. Nucleic Acids Res (2012) 2.09
Supervised group Lasso with applications to microarray data analysis. BMC Bioinformatics (2007) 1.99
Soybean WRKY-type transcription factor genes, GmWRKY13, GmWRKY21, and GmWRKY54, confer differential tolerance to abiotic stresses in transgenic Arabidopsis plants. Plant Biotechnol J (2008) 1.98
Clustering threshold gradient descent regularization: with applications to microarray studies. Bioinformatics (2006) 1.97
Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a systematic review and meta-analysis of comparative studies. Eur Urol (2012) 1.96
Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A. J Hepatol (2008) 1.95
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse. Proc Natl Acad Sci U S A (2004) 1.88
Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 1.85
Penalized methods for bi-level variable selection. Stat Interface (2009) 1.82
Ynamides: a modern functional group for the new millennium. Chem Rev (2010) 1.77
Toll-like receptors in inflammation, infection and cancer. Int Immunopharmacol (2007) 1.76
T cell factor 1 is required for group 2 innate lymphoid cell generation. Immunity (2013) 1.72
Combining multiple markers for classification using ROC. Biometrics (2007) 1.72
MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3. Int J Cancer (2011) 1.70
Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs. Am J Physiol Heart Circ Physiol (2008) 1.66
Regularized gene selection in cancer microarray meta-analysis. BMC Bioinformatics (2009) 1.64
Dietary intakes of mushrooms and green tea combine to reduce the risk of breast cancer in Chinese women. Int J Cancer (2009) 1.63
Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol (2004) 1.62
Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction. Proc Natl Acad Sci U S A (2005) 1.59
Definition of the landscape of promoter DNA hypomethylation in liver cancer. Cancer Res (2011) 1.58
MicroRNA-143 as a tumor suppressor for bladder cancer. J Urol (2009) 1.56
[Recent research progress of anti-tumor mechnism matrine]. Zhongguo Zhong Yao Za Zhi (2004) 1.55
The F-box protein AhSLF-S2 physically interacts with S-RNases that may be inhibited by the ubiquitin/26S proteasome pathway of protein degradation during compatible pollination in Antirrhinum. Plant Cell (2004) 1.54
Penalized feature selection and classification in bioinformatics. Brief Bioinform (2008) 1.51
The emergence of allenamides in organic synthesis. Acc Chem Res (2003) 1.50
The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation. Mol Cell Biol (2003) 1.50
Lanthanum enhances in vitro osteoblast differentiation via pertussis toxin-sensitive gi protein and ERK signaling pathway. J Cell Biochem (2008) 1.49
Identification of interleukin-6 promoter polymorphisms in the Chinese Han population and their functional significance. Crit Care Med (2008) 1.49
Characteristics and prognosis analysis of additional chromosome abnormalities in newly diagnosed acute promyelocytic leukemia treated with arsenic trioxide as the front-line therapy. Leuk Res (2013) 1.48
Interleukin-6 levels in female rats with protamine sulfate-induced chronic cystitis treated with hyaluronic acid. Int J Urol (2013) 1.45
Effects of procainamide and sotalol on restitution properties, dispersion of refractoriness, and ventricular fibrillation activation patterns in pigs. J Cardiovasc Electrophysiol (2008) 1.44
A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep (2013) 1.44
Identification of sequence variants in genetic disease-causing genes using targeted next-generation sequencing. PLoS One (2011) 1.44
Interleukin-6-independent expression of glucocorticoid receptor is upregulated by triptolide in multiple myeloma. Leuk Lymphoma (2009) 1.42
Insertion of an alkene into an ester: intramolecular oxyacylation reaction of alkenes through acyl C-O bond activation. Angew Chem Int Ed Engl (2011) 1.42
Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma. Arch Surg (2009) 1.42
Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology (2007) 1.41
Additive risk survival model with microarray data. BMC Bioinformatics (2007) 1.40
Copper sulfate-pentahydrate-1,10-phenanthroline catalyzed amidations of alkynyl bromides. Synthesis of heteroaromatic amine substituted ynamides. Org Lett (2004) 1.38
Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors. PLoS One (2011) 1.38
Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. J Biol Chem (2010) 1.37
Low-temperature processed electron collection layers of graphene/TiO2 nanocomposites in thin film perovskite solar cells. Nano Lett (2013) 1.36
A polymorphism in the complement component C1qA correlates with prolonged response following rituximab therapy of follicular lymphoma. Clin Cancer Res (2008) 1.36
lncRNA H19/miR-675 axis represses prostate cancer metastasis by targeting TGFBI. FEBS J (2014) 1.36
Li Ion Conducting Polymer Gel Electrolytes Based on Ionic Liquid/PVDF-HFP Blends. J Electrochem Soc (2007) 1.36
CCAAT/enhancer binding protein alpha interacts with ZTA and mediates ZTA-induced p21(CIP-1) accumulation and G(1) cell cycle arrest during the Epstein-Barr virus lytic cycle. J Virol (2003) 1.33
A semiparametric approach for the nonparametric transformation survival model with multiple covariates. Biostatistics (2006) 1.32
miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer. PLoS One (2013) 1.31
Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics (2008) 1.31
Periods of highly synchronous, non-reentrant endocardial activation cycles occur during long-duration ventricular fibrillation. J Cardiovasc Electrophysiol (2010) 1.30
Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci (2009) 1.29
The soybean Dof-type transcription factor genes, GmDof4 and GmDof11, enhance lipid content in the seeds of transgenic Arabidopsis plants. Plant J (2007) 1.29
Gene expression analysis of photoreceptor cell loss in bbs4-knockout mice reveals an early stress gene response and photoreceptor cell damage. Invest Ophthalmol Vis Sci (2007) 1.28
Increased efficiency in cross-metathesis reactions of sterically hindered olefins. Org Lett (2008) 1.28
Integrative analysis of multiple cancer prognosis studies with gene expression measurements. Stat Med (2011) 1.27
Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case-control study. J Gen Virol (2008) 1.26
A critical role for the g protein-coupled receptor mFPR2 in airway inflammation and immune responses. J Immunol (2010) 1.26
Fiberglass needle electrodes for transmural cardiac mapping. IEEE Trans Biomed Eng (2002) 1.26
Soybean GmbZIP44, GmbZIP62 and GmbZIP78 genes function as negative regulator of ABA signaling and confer salt and freezing tolerance in transgenic Arabidopsis. Planta (2008) 1.25
Chiral Lewis acid-catalyzed highly enantioselective [4 + 3] cycloaddition reactions of nitrogen-stabilized oxyallyl cations derived from allenamides. J Am Chem Soc (2005) 1.25
B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation. Blood (2006) 1.25
Mold damage in homes and wheezing in infants. Ann Allergy Asthma Immunol (2006) 1.24
The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker. Hum Hered (2005) 1.24
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling. J Clin Invest (2010) 1.22
Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors. Cancer Res (2007) 1.22
Thermal intramolecular [4 + 2] cycloadditions of allenamides: a stereoselective tandem propargyl amide isomerization-cycloaddition. Org Lett (2009) 1.22
Stereoselective formal [3 + 3] cycloaddition approach to cis-1-azadecalins and synthesis of (-)-4a,8a-diepi-pumiliotoxin C. evidence for the first highly stereoselective 6pi-electron electrocyclic ring closures of 1-azatrienes. J Am Chem Soc (2002) 1.22
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo. Am J Physiol Cell Physiol (2008) 1.20
Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice. J Clin Invest (2011) 1.20
Two-locus heterogeneity cannot be distinguished from two-locus epistasis on the basis of affected-sib-pair data. Am J Hum Genet (2003) 1.20
The transmural activation sequence in porcine and canine left ventricle is markedly different during long-duration ventricular fibrillation. J Cardiovasc Electrophysiol (2007) 1.20
Intramural foci during long duration fibrillation in the pig ventricle. Circ Res (2008) 1.20
Stereoselective intramolecular [4 + 3] cycloadditions of nitrogen-stabilized chiral oxyallyl cations via epoxidation of N-tethered allenamides. J Am Chem Soc (2003) 1.20
Integrative analysis and variable selection with multiple high-dimensional data sets. Biostatistics (2011) 1.19
linc-UBC1 physically associates with polycomb repressive complex 2 (PRC2) and acts as a negative prognostic factor for lymph node metastasis and survival in bladder cancer. Biochim Biophys Acta (2013) 1.19
Intratumoral delivery of dendritic cells engineered to secrete both interleukin (IL)-12 and IL-18 effectively treats local and distant disease in association with broadly reactive Tc1-type immunity. Cancer Res (2003) 1.18
Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: comparison of T-cell lymphoma with and without hemophagocytic syndrome. Leuk Lymphoma (2008) 1.16
Regioselectivities of (4 + 3) cycloadditions between furans and oxazolidinone-substituted oxyallyls. Org Lett (2010) 1.15
Prognostic significance of circulating tumor cells in non-small-cell lung cancer patients: a meta-analysis. PLoS One (2013) 1.15
Regulation of expression of the Epstein-Barr virus BamHI-A rightward transcripts. J Virol (2005) 1.14
Catalytic asymmetric synthesis of chiral allylic amines. Evaluation of ferrocenyloxazoline palladacycle catalysts and imidate motifs. J Org Chem (2005) 1.14
Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem Cells (2011) 1.14
A tandem epoxidation/stereoselective intramolecular [4+3] cycloaddition reaction involving nitrogen-stabilized oxyallyl cations derived from chiral allenamides. Angew Chem Int Ed Engl (2004) 1.13
Identification of genes associated with multiple cancers via integrative analysis. BMC Genomics (2009) 1.12
Regional differences in ventricular fibrillation in the open-chest porcine left ventricle. Circ Res (2002) 1.12
Highly stereoselective [4 + 3] cycloadditions of nitrogen-stabilized oxyallyl cations with pyrroles: an approach to parvineostemonine. Org Lett (2007) 1.11