The soya isoflavone content of rat diet can increase anxiety and stress hormone release in the male rat.

PubWeight™: 0.91‹?›

🔗 View Article (PMID 12618915)

Published in Psychopharmacology (Berl) on March 05, 2003

Authors

David E Hartley1, Jessica E Edwards, Claire E Spiller, Nazmul Alom, Sonia Tucci, Pallab Seth, Mary L Forsling, Sandra E File

Author Affiliations

1: Psychopharmacology Research Unit, Centre for Neuroscience, Hodgkin Building, Kings College London, Guy's Campus, SE1 1UL, London, UK. david.2.hartley@kcl.ac.uk

Articles citing this

A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior. Neuropsychopharmacology (2006) 1.90

The pros and cons of phytoestrogens. Front Neuroendocrinol (2010) 1.69

Open- and closed-formula laboratory animal diets and their importance to research. J Am Assoc Lab Anim Sci (2009) 0.98

Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats. Horm Behav (2008) 0.95

Estrogenic plant consumption predicts red colobus monkey (Procolobus rufomitratus) hormonal state and behavior. Horm Behav (2012) 0.83

Effects of genistein in the maternal diet on reproductive development and spatial learning in male rats. Horm Behav (2010) 0.81

Effects of dietary soy isoflavones on health, steroidogenesis, and thyroid gland function in dogs. Am J Vet Res (2009) 0.77

Adult emotionality and neural plasticity as a function of adolescent nutrient supplementation in male rats. Pharmacol Biochem Behav (2015) 0.76

Assessment of the Effects of 6 Standard Rodent Diets on Binge-Like and Voluntary Ethanol Consumption in Male C57BL/6J Mice. Alcohol Clin Exp Res (2015) 0.76

Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours. Proc Nutr Soc (2016) 0.76

Chromosomal assignment of quantitative trait loci influencing baseline circulating total cholesterol level in male laboratory mice: report of a consomic strain survey and comparison with published results. BMC Res Notes (2015) 0.75

Dietary soy may not confound acute experimental stroke infarct volume outcomes in ovariectomized female rats. Lab Anim (2010) 0.75

Phytoestrogens β -sitosterol and genistein have limited effects on reproductive endpoints in a female fish, Betta splendens. Biomed Res Int (2014) 0.75

Endocrine Disruption of Vasopressin Systems and Related Behaviors. Front Endocrinol (Lausanne) (2017) 0.75

Articles cited by this

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology (1998) 9.57

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods (1985) 9.05

A review of 25 years of the social interaction test. Eur J Pharmacol (2003) 2.74

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav (1986) 2.73

Can social interaction be used to measure anxiety? Br J Pharmacol (1978) 2.50

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs. J Neurosci Methods (1980) 2.26

Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats. Endocrinology (1997) 2.17

Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones. Lab Invest (2001) 1.96

Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype. J Neurobiol (1998) 1.76

Exploration of mice in a black and white test box: validation as a model of anxiety. Pharmacol Biochem Behav (1989) 1.64

A case of a laboratory animal feed with high estrogenic activity and its impact on in vivo responses to exogenously administered estrogens. Environ Health Perspect (1998) 1.55

Soy phytoestrogens improve radial arm maze performance in ovariectomized retired breeder rats and do not attenuate benefits of 17beta-estradiol treatment. Menopause (2000) 1.52

Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study. Environ Health Perspect (1998) 1.46

The estrogen receptor beta subtype: a novel mediator of estrogen action in neuroendocrine systems. Front Neuroendocrinol (1998) 1.45

P rats develop physical dependence on alcohol via voluntary drinking: changes in seizure thresholds, anxiety, and patterns of alcohol drinking. Alcohol Clin Exp Res (2000) 1.45

Emerging concepts of structure-function dynamics in adult brain: the hypothalamo-neurohypophysial system. Prog Neurobiol (1990) 1.41

Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats. J Nutr (1997) 1.35

Neurobehavioral effects of dietary soy phytoestrogens. Neurotoxicol Teratol (2002) 1.32

Estrogenic and antiproliferative activities on MCF-7 human breast cancer cells by flavonoids. Cancer Lett (1998) 1.31

Bimodal modulation by nicotine of anxiety in the social interaction test: role of the dorsal hippocampus. Behav Neurosci (1998) 1.26

Role of corticotropin-releasing factor and urocortin within the basolateral amygdala of rats in anxiety and panic responses. Behav Brain Res (1999) 1.19

Corticosterone response to the plus-maze: high correlation with risk assessment in rats and mice. Physiol Behav (2000) 1.19

Dual effects of phytoestrogens result in u-shaped dose-response curves. Environ Health Perspect (2002) 1.12

Corticotropin-releasing factor has an anxiogenic action in the social interaction test. Horm Behav (1987) 1.11

Estrogenic isoflavones in rodent diets. Toxicol Lett (2002) 1.11

Stress and the hypothalamo-pituitary-adrenal axis: acute, chronic and immunological activation. J Endocrinol (1992) 1.10

Studies on the role of ACTH and of 5-HT in anxiety, using an animal model. J Pharm Pharmacol (1978) 1.10

Expression of estrogen receptor-beta messenger ribonucleic acid in oxytocin and vasopressin neurons of the rat supraoptic and paraventricular nuclei. Endocrinology (1998) 1.09

Handling history of rats modifies behavioural effects of drugs in the elevated plus-maze test of anxiety. Eur J Pharmacol (1993) 1.07

Flumazenil but not nitrendipine reverses the increased anxiety during ethanol withdrawal in the rat. Psychopharmacology (Berl) (1989) 1.07

Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens. BMC Neurosci (2001) 1.07

Release of vasopressin within the rat paraventricular nucleus in response to emotional stress: a novel mechanism of regulating adrenocorticotropic hormone secretion? J Neurosci (1996) 1.02

Estrogen-specific 17 beta-hydroxysteroid oxidoreductase type 1 (E.C. 1.1.1.62) as a possible target for the action of phytoestrogens. Proc Soc Exp Biol Med (1995) 1.01

Vasopressin administration modulates anxiety-related behavior in rats. Physiol Behav (1998) 1.01

Anxiogenic responses of rats on withdrawal from chronic ethanol treatment: effects of tianeptine. Alcohol Alcohol (1993) 0.98

Soy isoflavone supplements antagonize reproductive behavior and estrogen receptor alpha- and beta-dependent gene expression in the brain. Endocrinology (2001) 0.95

Dietary soy phytoestrogens produce anxiolytic effects in the elevated plus-maze. Brain Res (2001) 0.95

Genistein action in the prepubertal mammary gland in a chemoprevention model. Carcinogenesis (2002) 0.94

Time-dependent induction of anxiogenic-like effects after central infusion of urocortin or corticotropin-releasing factor in the rat. Psychopharmacology (Berl) (2001) 0.94

Corticosterone -- an anxiogenic or an anxiolytic agent? J Pharm Pharmacol (1979) 0.94

The anxiogenic action of benzodiazepine antagonists. Neuropharmacology (1982) 0.94

Raised corticosterone in the rat after exposure to the elevated plus-maze. Psychopharmacology (Berl) (1994) 0.91

Dissociation of oxytocin, vasopressin and corticotropin secretion during different types of stress. Life Sci (1984) 0.91

Daidzein and genistein but not their glucosides are absorbed from the rat stomach. FEBS Lett (1999) 0.91

The effect of treatment regimen on the development of tolerance to the sedative and anxiolytic effects of diazepam. Psychopharmacology (Berl) (1999) 0.89

Pituitary and plasma vasopressin concentrations and fluid balance throughout the oestrous cycle of the rat. J Endocrinol (1988) 0.88

The effects of estrogen and progesterone on corticotropin-releasing hormone and arginine vasopressin messenger ribonucleic acid levels in the paraventricular nucleus and supraoptic nucleus of the rhesus monkey. Endocrinology (1999) 0.88

Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal. Prog Neuropsychopharmacol Biol Psychiatry (1992) 0.88

Effects of acute and chronic fluoxetine treatment of CRH-induced anxiety. Neuroreport (1999) 0.86

Effect of ovarian steroids on vasopressin secretion. J Endocrinol (1982) 0.86

Neurobehavioral actions of coumestrol and related isoflavonoids in rodents. Neurotoxicol Teratol (2002) 0.86

Maternal and perinatal brain aromatase: effects of dietary soy phytoestrogens. Brain Res Dev Brain Res (2001) 0.85

Phytoestrogens decrease brain calcium-binding proteins but do not alter hypothalamic androgen metabolizing enzymes in adult male rats. Brain Res (2000) 0.85

The effect of minor tranquilizers on stress-induced increases in rat plasma corticosteroids. Psychopharmacologia (1974) 0.85

The sensitivity of the rat corticosterone response to environmental manipulations and to chronic chlordiazepoxide treatment. Physiol Behav (1980) 0.83

Single or repeated mild stress increases synthesis and release of hypothalamic corticotropin-releasing factor. Brain Res (1988) 0.83

Comparison of adaptive responses in familiar and novel environments: modulatory factors. Ann N Y Acad Sci (1988) 0.83

Mode of killing and plasma corticosterone concentrations in the rat. Lab Anim Sci (1973) 0.82

Low but not high doses of buspirone reduce the anxiogenic effects of diazepam withdrawal. Psychopharmacology (Berl) (1991) 0.81

Chronic exposure to noise modifies the anxiogenic response, but not the hypoactivity, detected on withdrawal from chronic ethanol treatment. Psychopharmacology (Berl) (1994) 0.81

Vasopressin and oxytocin release during prolonged environmental hypoxia in the rat. Thorax (1997) 0.81

Effects of the beta-carboline, FG 7142, in the social interaction test of anxiety and the holeboard: correlations between behaviour and plasma concentrations. Pharmacol Biochem Behav (1985) 0.80

The anxiogenic action of Ro 15-1788 is reversed by chronic, but not by acute, treatment with chlordiazepoxide. Brain Res (1984) 0.79

Influence of oxytocin on sodium excretion in the anaesthetized Brattleboro rat. J Endocrinol (1991) 0.79

Interactions of ethyl-beta-carboline-3-carboxylate and Ro 15-1788 with CGS 8216 in an animal model of anxiety. Neurosci Lett (1983) 0.79

Relationships between plasma corticosteroids and benzodiazepines in stress. J Pharmacol Exp Ther (1979) 0.79

Effect of ovariectomy and treatment with ovarian steroids on vasopressin release and fluid balance in the rat. J Endocrinol (1990) 0.78

The effect of ketotifen in rodent models of anxiety and on the behavioural consequences of withdrawing from treatment with drugs of abuse. Naunyn Schmiedebergs Arch Pharmacol (1990) 0.78

Brain benzodiazepine receptor-mediated effects on plasma catecholamine and corticosterone concentrations in rats. Brain Res Bull (1990) 0.78

The validation of animal tests of anxiety--pharmacological implications. Pol J Pharmacol Pharm (1985) 0.77

Plasma corticosterone responses to stress following chronic oral administration of diazepam in the rat. J Pharm Pharmacol (1979) 0.77

Effects of buspirone and chlordiazepoxide on plasma catecholamine and corticosterone levels in stressed and nonstressed rats. Pharmacol Biochem Behav (1991) 0.77

The benzodiazepine receptor and its role in anxiety. Br J Psychiatry (1988) 0.76

Benzodiazepine withdrawal: behavioural pharmacology and neurochemical changes. Biochem Soc Symp (1993) 0.76

Effects of diazepam on conflict behaviour and on plasma corticosterone levels in male and female rats. Naunyn Schmiedebergs Arch Pharmacol (1996) 0.76

Flumazenil prevents the development of chlordiazepoxide withdrawal in rats tested in the social interaction test of anxiety. Psychopharmacology (Berl) (1989) 0.76

Chlordiazepoxide enhances the anxiogenic action of CGS 8216 in the social interaction test: evidence for benzodiazepine withdrawal? Pharmacol Biochem Behav (1985) 0.75

Effects of ACTH4--10 in the social interaction test of anxiety. Brain Res (1979) 0.75

Effect of KCA-098 on the function of osteoblast-like cells and the formation of TRAP-positive multinucleated cells in a mouse bone marrow cell population. Biochem Pharmacol (1996) 0.75

Plasma corticosterone levels in rats killed sequentially at the "trough" or "peak" of the adrenocortical cycle. J Endocrinol (1971) 0.75

Articles by these authors

A review of 25 years of the social interaction test. Eur J Pharmacol (2003) 2.74

Endocannabinoid system and stress and anxiety responses. Pharmacol Biochem Behav (2005) 1.74

Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption. J Psychopharmacol (2011) 1.23

Nicotine and cannabinoids: parallels, contrasts and interactions. Neurosci Biobehav Rev (2006) 1.20

Binge drinking and sex: effects on mood and cognitive function in healthy young volunteers. Pharmacol Biochem Behav (2004) 1.10

Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones. Pharmacol Biochem Behav (2003) 1.06

Unconditioned and conditioned anxiogenic effects of the cannabinoid receptor agonist CP 55,940 in the social interaction test. Pharmacol Biochem Behav (2004) 1.04

Cognitive effects of modafinil in student volunteers may depend on IQ. Pharmacol Biochem Behav (2005) 1.04

Nicotinic--serotonergic interactions in brain and behaviour. Pharmacol Biochem Behav (2002) 1.00

Ecstasy (MDMA)-induced hyponatraemia is associated with genetic variants in CYP2D6 and COMT. J Psychopharmacol (2012) 0.99

Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl) (2003) 0.98

Cholecystokinin stimulation leads to increased oxytocin secretion in women. Eur J Surg (2002) 0.94

Age-associated sex differences in response to food deprivation in two animal tests of anxiety. Neurosci Biobehav Rev (2003) 0.93

Modafinil affects mood, but not cognitive function, in healthy young volunteers. Hum Psychopharmacol (2003) 0.91

The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers. Pharmacol Biochem Behav (2004) 0.90

Does modafinil enhance cognitive performance in young volunteers who are not sleep-deprived? J Clin Psychopharmacol (2005) 0.89

Chronic treatment with modafinil may not be beneficial in patients with chronic fatigue syndrome. J Psychopharmacol (2005) 0.89

Involvement of 5-HT1A receptors in animal tests of anxiety and depression: evidence from genetic models. Stress (2003) 0.88

Differential cognitive effects of Ginkgo biloba after acute and chronic treatment in healthy young volunteers. Psychopharmacology (Berl) (2005) 0.83

Soya phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male rats. Neurosci Lett (2003) 0.82

Cognitive function in late versus early postmenopausal stage. Maturitas (2006) 0.82

Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba. J Psychopharmacol (2005) 0.80

Conditioned anxiety to nicotine. Psychopharmacology (Berl) (2002) 0.79

Effects on cognition and mood in postmenopausal women of 1-week treatment with Ginkgo biloba. Pharmacol Biochem Behav (2003) 0.79

Release of vasopressin during suppression of oestrous cycle in rat by zoladex and hypovolemic challenge. J Ayub Med Coll Abbottabad (2006) 0.78

Haloperidol abolished glutamate release evoked by photic stimulation of the visual cortex in rats. Neurosci Lett (2002) 0.78

Dietary restriction and nicotine can reduce anxiety in female rats. Neuropsychopharmacology (2003) 0.78

Cognitive effects of 10 years of hormone-replacement therapy with tibolone. J Clin Psychopharmacol (2002) 0.78

Does drinking have effects on mood and cognition in male and female students? Pharmacol Biochem Behav (2004) 0.77

Oxytocin and cholecystokinin secretion in women with colectomy. BMC Gastroenterol (2004) 0.77

Renal response to arginine vasopressin during the oestrous cycle in the rat: comparison of glucose and saline infusion using physiological doses of vasopressin. Exp Physiol (2002) 0.76

Addiction and pain: cannabinoid and opioid interactions. Curr Drug Targets (2010) 0.75

Mood changes after cognitive testing in late middle-age: impacts of sex and habitual alcohol consumption. Pharmacol Biochem Behav (2004) 0.75