Published in Horm Behav on November 21, 2008
Estrogen actions in the brain and the basis for differential action in men and women: a case for sex-specific medicines. Pharmacol Rev (2010) 2.13
Sex differences in psychopathology: of gonads, adrenals and mental illness. Physiol Behav (2009) 1.39
Estrogen receptor beta regulates the expression of tryptophan-hydroxylase 2 mRNA within serotonergic neurons of the rat dorsal raphe nuclei. Neuroscience (2009) 1.12
From synapse to nucleus: novel targets for treating depression. Neuropharmacology (2009) 1.06
Anxiogenic effects of developmental bisphenol A exposure are associated with gene expression changes in the juvenile rat amygdala and mitigated by soy. PLoS One (2012) 0.99
Neonatal agonism of ERβ impairs male reproductive behavior and attractiveness. Horm Behav (2011) 0.83
Estrogen provides neuroprotection against brain edema and blood brain barrier disruption through both estrogen receptors α and β following traumatic brain injury. Iran J Basic Med Sci (2015) 0.80
Reproductive experience modifies the effects of estrogen receptor alpha activity on anxiety-like behavior and corticotropin releasing hormone mRNA expression. Horm Behav (2011) 0.80
Oestrogen receptor beta is involved in the actions of oestrogens in the brain for affective behaviour, but not trophic effects in peripheral tissues. J Neuroendocrinol (2009) 0.79
Influence of ERβ selective agonism during the neonatal period on the sexual differentiation of the rat hypothalamic-pituitary-gonadal (HPG) axis. Biol Sex Differ (2012) 0.78
Soy but not bisphenol A (BPA) induces hallmarks of polycystic ovary syndrome (PCOS) and related metabolic co-morbidities in rats. Reprod Toxicol (2014) 0.78
Adult emotionality and neural plasticity as a function of adolescent nutrient supplementation in male rats. Pharmacol Biochem Behav (2015) 0.76
Pharmacokinetics of the estrogen receptor subtype-selective ligands, PPT and DPN: quantification using UPLC-ES/MS/MS. J Pharm Biomed Anal (2012) 0.76
Phytoestrogens enhance the vascular actions of the endocannabinoid anandamide in mesenteric beds of female rats. Int J Hypertens (2012) 0.75
Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature (2003) 17.52
Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci U S A (1996) 10.94
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology (1997) 10.08
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology (1998) 9.57
Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods (1985) 9.05
Sequence and expression of human estrogen receptor complementary DNA. Science (1986) 4.36
Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate. Curr Biol (2006) 3.88
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones. J Nutr (2002) 3.14
Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements. J Nutr (2001) 2.97
Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat. Pharmacol Biochem Behav (1986) 2.73
Novel actions of estrogen receptor-beta on anxiety-related behaviors. Endocrinology (2004) 2.20
Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinology (2000) 1.98
A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior. Neuropsychopharmacology (2006) 1.90
Interaction of phytoestrogens with estrogen receptors alpha and beta. Biol Pharm Bull (2001) 1.90
Resveratrol as an anticancer nutrient: molecular basis, open questions and promises. J Nutr Biochem (2005) 1.84
Estrogen receptor-beta: recent lessons from in vivo studies. Mol Endocrinol (2006) 1.77
Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev (2005) 1.75
Characterization of the biological roles of the estrogen receptors, ERalpha and ERbeta, in estrogen target tissues in vivo through the use of an ERalpha-selective ligand. Endocrinology (2002) 1.74
Phytoestrogen content of purified, open- and closed-formula laboratory animal diets. Lab Anim Sci (1999) 1.73
S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr (2005) 1.73
Oestrogen receptor knockout mice: roles for oestrogen receptors alpha and beta in reproductive tissues. Reproduction (2003) 1.67
Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus. Endocrinology (2003) 1.66
ERbeta-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats. Neuropsychopharmacology (2005) 1.61
A case of a laboratory animal feed with high estrogenic activity and its impact on in vivo responses to exogenously administered estrogens. Environ Health Perspect (1998) 1.55
Bioavailability, disposition, and dose-response effects of soy isoflavones when consumed by healthy women at physiologically typical dietary intakes. J Nutr (2003) 1.45
Effects of estrogen on activity and fear-related behaviors in mice. Horm Behav (2001) 1.45
Distribution of estrogen receptor alpha and beta immunoreactive profiles in the postnatal rat brain. Brain Res Dev Brain Res (2003) 1.43
An alternate pathway for androgen regulation of brain function: activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5alpha-androstane-3beta,17beta-diol. Horm Behav (2007) 1.43
Neonatal genistein or bisphenol-A exposure alters sexual differentiation of the AVPV. Neurotoxicol Teratol (2006) 1.41
Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women. Am J Clin Nutr (2003) 1.38
Testosterone increases analgesia, anxiolysis, and cognitive performance of male rats. Cogn Affect Behav Neurosci (2001) 1.28
Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior. Neuroscience (2005) 1.26
ERbeta-selective SERMs produce mnemonic-enhancing effects in the inhibitory avoidance and water maze tasks. Neurobiol Learn Mem (2005) 1.24
Sex with knockout models: behavioral studies of estrogen receptor alpha. Brain Res (1999) 1.23
Lignans and isoflavonoids in plasma and prostatic fluid in men: samples from Portugal, Hong Kong, and the United Kingdom. Prostate (1997) 1.23
Antidepressant effects of ERbeta-selective estrogen receptor modulators in the forced swim test. Pharmacol Biochem Behav (2004) 1.22
Comparative distribution of estrogen receptor-alpha (ER-alpha) and beta (ER-beta) mRNA in the rat pituitary, gonad, and reproductive tract. Steroids (1998) 1.22
Distribution and differences of estrogen receptor beta immunoreactivity in the brain of adult male and female rats. Brain Res (2002) 1.18
Treatment with an anabolic-androgenic steroid affects anxiety-related behavior and alters the sensitivity of cortical GABAA receptors in the rat. Horm Behav (1993) 1.17
Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback. Biol Reprod (2003) 1.17
Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. J Steroid Biochem Mol Biol (2000) 1.14
Behavioral effects of endocrine-disrupting substances: phytoestrogens. ILAR J (2004) 1.13
Expression of estrogen receptor alpha and beta during mouse embryogenesis. Mech Dev (1999) 1.13
Anxiolytic-like actions of testosterone in the burying behavior test: role of androgen and GABA-benzodiazepine receptors. Psychoneuroendocrinology (2005) 1.11
Resveratrol acts as an estrogen receptor (ER) agonist in breast cancer cells stably transfected with ER alpha. Int J Cancer (2003) 1.11
Neuroprotective effects of resveratrol against traumatic brain injury in immature rats. Neurosci Lett (2007) 1.09
An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs. J Pharmacol Toxicol Methods (1993) 1.08
Variations in isoflavone levels in soy foods and soy protein isolates and issues related to isoflavone databases and food labeling. J Agric Food Chem (2003) 1.07
Estrogen action in mood and neurodegenerative disorders: estrogenic compounds with selective properties-the next generation of therapeutics. Endocrine (2005) 1.00
trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in healthy rats. J Nutr (2005) 1.00
The identification of the weak oestrogen equol [7-hydroxy-3-(4'-hydroxyphenyl)chroman] in human urine. Biochem J (1982) 0.99
Estrogen receptor beta-deficient female mice develop a bladder phenotype resembling human interstitial cystitis. Proc Natl Acad Sci U S A (2007) 0.98
Global transcription profiling of estrogen activity: estrogen receptor alpha regulates gene expression in the kidney. Endocrinology (2003) 0.94
Biological role of pituitary estrogen receptors ERalpha and ERbeta on progesterone receptor expression and action and on gonadotropin and prolactin secretion in the rat. Neuroendocrinology (2004) 0.93
High-performance liquid chromatographic analysis of phytoestrogens in soy protein preparations with ultraviolet, electrochemical and thermospray mass spectrometric detection. J Chromatogr (1987) 0.92
Transcriptional regulation by phytoestrogens in neuronal cell lines. Mol Cell Endocrinol (2005) 0.92
The soya isoflavone content of rat diet can increase anxiety and stress hormone release in the male rat. Psychopharmacology (Berl) (2003) 0.91
Evidence that GABAergic neurons in the preoptic area of the rat brain are targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin during development. Environ Health Perspect (2002) 0.88
Dietary soy supplements produce opposite effects on anxiety in intact male and female rats in the elevated plus-maze. Behav Neurosci (2005) 0.87
Estrogen receptor beta is expressed in human embryonic brain cells and is regulated by 17beta-estradiol. Eur J Neurosci (2004) 0.86
Increased aggressive behavior and decreased affiliative behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones. Horm Behav (2004) 0.86
Phytoestrogens decrease brain calcium-binding proteins but do not alter hypothalamic androgen metabolizing enzymes in adult male rats. Brain Res (2000) 0.85
trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo. Arch Pharm Res (2008) 0.82
Estrogen receptor beta agonists in neurobehavioral investigations. Curr Opin Investig Drugs (2008) 0.82
Alternative therapies for postmenopausal women. Int J Fertil Womens Med (2005) 0.81
The neurobehavioral effects of phytoestrogens in male Syrian hamsters. Brain Res (2004) 0.81
Identification and quantitative estimation of a lignan in human and bovine semen. J Reprod Fertil (1982) 0.80
Long-term retention of estradiol by brain cell nuclei and female rat sexual behavior. Brain Res (1979) 0.77
Bioavailability of PAHs: effects of soot carbon and PAH source. Environ Sci Technol (2004) 1.12
Impact of neonatal exposure to the ERalpha agonist PPT, bisphenol-A or phytoestrogens on hypothalamic kisspeptin fiber density in male and female rats. Neurotoxicology (2009) 1.11
Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior. Front Behav Neurosci (2009) 1.04
Analysis of chlorothalonil and degradation products in soil and water by GC/MS and LC/MS. Chemosphere (2007) 0.99
Anxiogenic effects of developmental bisphenol A exposure are associated with gene expression changes in the juvenile rat amygdala and mitigated by soy. PLoS One (2012) 0.99
Determination of brevetoxin in recent marine sediments. Chemosphere (2008) 0.94
Increased toxicity of Karenia brevis during phosphate limited growth: ecological and evolutionary implications. PLoS One (2013) 0.92
Calibration and field verification of semipermeable membrane devices for measuring polycyclic aromatic hydrocarbons in water. Environ Sci Technol (2002) 0.91
Environmental occurrence and reproductive effects of the pharmaceutical fluoxetine in native freshwater mussels. Environ Toxicol Chem (2010) 0.86
Semipermeable membrane devices accumulate conserved ratios of sterane and hopane petroleum biomarkers. Chemosphere (2003) 0.84
Neonatal agonism of ERalpha masculinizes serotonergic (5-HT) projections to the female rat ventromedial nucleus of the hypothalamus (VMN) but does not impair lordosis. Behav Brain Res (2008) 0.80
Acute and chronic toxicity of technical-grade pesticides to glochidia and juveniles of freshwater mussels (Unionidae). Environ Toxicol Chem (2007) 0.80
Acute and chronic toxicity of glyphosate compounds to glochidia and juveniles of Lampsilis siliquoidea (Unionidae). Environ Toxicol Chem (2007) 0.79
Novel hydrophobicity ruler approach for determining the octanol/water partition coefficients of very hydrophobic compounds via their polymer/solvent solution distribution coefficients. Anal Chem (2005) 0.78
Acute and chronic toxicity of pesticide formulations (atrazine, chlorpyrifos, and permethrin) to glochidia and juveniles of Lampsilis siliquoidea. Environ Toxicol Chem (2007) 0.78
Impact of vegetation on sedimentary organic matter composition and polycyclic aromatic hydrocarbon attenuation. Environ Sci Technol (2005) 0.78
Influence of water quality and associated contaminants on survival and growth of the endangered Cape Fear shiner (Notropis mekistocholas). Environ Toxicol Chem (2006) 0.77
Regression method of the hydrophobicity ruler approach for determining octanol/water partition coefficients of very hydrophobic compounds. Chemosphere (2006) 0.76
Environmental fate of chlorothalonil in a Costa Rican banana plantation. Chemosphere (2007) 0.75
Assessment of Polycyclic Aromatic Hydrocarbon Contamination of Breeding Pools Utilized by the Puerto Rican Crested Toad, Peltophryne lemur. ISRN Toxicol (2012) 0.75
Assessing organic contaminants in fish: comparison of a nonlethal tissue sampling technique to mobile and stationary passive sampling devices. Environ Sci Technol (2005) 0.75
Effects of lead on Na⁺, K⁺-ATPase and hemolymph ion concentrations in the freshwater mussel Elliptio complanata. Environ Toxicol (2010) 0.75
Assessment of the effect of varying soil organic matter content on the bioavailability of malathion to the common nightcrawler, Lumbricus terrestris L. Bull Environ Contam Toxicol (2008) 0.75