Published in Q Rev Biophys on November 01, 2002
Running in reverse: the structural basis for translocation polarity in hexameric helicases. Cell (2009) 3.38
Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase. Cell (2007) 3.09
UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli. EMBO J (2004) 2.59
Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. J Virol (2004) 2.29
Single-molecule assay reveals strand switching and enhanced processivity of UvrD. Proc Natl Acad Sci U S A (2004) 2.24
Structural basis for the enhancement of eIF4A helicase activity by eIF4G. Genes Dev (2005) 1.83
Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A. Nucleic Acids Res (2004) 1.60
Spectroscopic studies of position-specific DNA "breathing" fluctuations at replication forks and primer-template junctions. Proc Natl Acad Sci U S A (2009) 1.49
DEAD-box RNA helicases in Escherichia coli. Nucleic Acids Res (2006) 1.44
Replication termination in Escherichia coli: structure and antihelicase activity of the Tus-Ter complex. Microbiol Mol Biol Rev (2005) 1.38
Displacement of a DNA binding protein by Dda helicase. Nucleic Acids Res (2006) 1.30
DNA looping and translocation provide an optimal cleavage mechanism for the type III restriction enzymes. EMBO J (2007) 1.28
DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases. Nucleic Acids Res (2006) 1.26
Mechanisms of a ring shaped helicase. Nucleic Acids Res (2006) 1.26
Monitoring helicase activity with molecular beacons. Biotechniques (2008) 1.19
Understanding helicases as a means of virus control. Curr Pharm Des (2006) 1.18
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis. Mol Cell Biol (2006) 1.15
DNA mechanics as a tool to probe helicase and translocase activity. Nucleic Acids Res (2006) 1.13
DnaB helicase activity is modulated by DNA geometry and force. Biophys J (2010) 1.12
Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5'-triphosphatase activities. J Virol (2004) 1.11
Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. J Mol Biol (2011) 1.04
NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. J Biol Chem (2008) 1.04
Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations. Nucleic Acids Res (2004) 1.03
Sequence-dependent base pair stepping dynamics in XPD helicase unwinding. Elife (2013) 1.02
Single-molecule FRET and linear dichroism studies of DNA breathing and helicase binding at replication fork junctions. Proc Natl Acad Sci U S A (2013) 1.01
Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem (2008) 1.00
Fifty years of DNA "Breathing": Reflections on old and new approaches. Biopolymers (2013) 0.99
Structure-function analysis of the RNA helicase maleless. Nucleic Acids Res (2007) 0.99
Characterization of the ATPase activity of the Escherichia coli RecG protein reveals that the preferred cofactor is negatively supercoiled DNA. J Mol Biol (2007) 0.99
Lessons learned from UvrD helicase: mechanism for directional movement. Annu Rev Biophys (2010) 0.96
Kinetic control of Mg2+-dependent melting of duplex DNA ends by Escherichia coli RecBC. J Mol Biol (2008) 0.93
Fuel specificity of the hepatitis C virus NS3 helicase. J Mol Biol (2009) 0.93
Influence of DNA end structure on the mechanism of initiation of DNA unwinding by the Escherichia coli RecBCD and RecBC helicases. J Mol Biol (2008) 0.92
Magnetic tweezers for the study of DNA tracking motors. Methods Enzymol (2010) 0.90
Protein and DNA effectors control the TraI conjugative helicase of plasmid R1. J Bacteriol (2009) 0.90
Thermodynamic analysis of the structure-function relationship in the total DNA-binding site of enzyme-DNA complexes. Methods Enzymol (2009) 0.88
Discovering new medicines targeting helicases: challenges and recent progress. J Biomol Screen (2013) 0.85
The primary and secondary translocase activities within E. coli RecBC helicase are tightly coupled to ATP hydrolysis by the RecB motor. J Mol Biol (2012) 0.85
Use of a restriction enzyme-digested PCR product as substrate for helicase assays. Nucleic Acids Res (2005) 0.84
Mechanisms of interactions of the nucleotide cofactor with the RepA protein of plasmid RSF1010. Binding dynamics studied using the fluorescence stopped-flow method. Biochemistry (2009) 0.84
Development and evaluation of a structural model for SF1B helicase Dda. Biochemistry (2009) 0.84
Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. J Biomol NMR (2009) 0.83
Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers. DNA Repair (Amst) (2014) 0.83
A novel DNA helicase with strand-annealing activity from the crenarchaeon Sulfolobus solfataricus. Biochem J (2007) 0.82
Mechanism of NTP hydrolysis by the Escherichia coli primary replicative helicase DnaB protein. 2. Nucleotide and nucleic acid specificities. Biochemistry (2009) 0.81
DNA unwinding by ring-shaped T4 helicase gp41 is hindered by tension on the occluded strand. PLoS One (2013) 0.79
Dynamics of the ssDNA recognition by the RepA hexameric helicase of plasmid RSF1010: analyses using fluorescence stopped-flow intensity and anisotropy methods. J Mol Biol (2009) 0.78
Helicase processivity and not the unwinding velocity exhibits universal increase with force. Biophys J (2015) 0.76
Escherichia coli DnaB helicase-DnaC protein complex: allosteric effects of the nucleotides on the nucleic acid binding and the kinetic mechanism of NTP hydrolysis. 3. Biochemistry (2009) 0.76
5' to 3' Unfolding Directionality of DNA Secondary Structures by Replication Protein A: G-QUADRUPLEXES AND DUPLEXES. J Biol Chem (2016) 0.76
A mechanistic study of helicases with magnetic traps. Protein Sci (2017) 0.75
Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase are Involved in Unwinding G-quadruplex DNA. J Biol Chem (2017) 0.75
Salt resistance genes revealed by functional metagenomics from brines and moderate-salinity rhizosphere within a hypersaline environment. Front Microbiol (2015) 0.75
Helicase mechanisms and the coupling of helicases within macromolecular machines. Part II: Integration of helicases into cellular processes. Q Rev Biophys (2003) 1.99
Thinking quantitatively about transcriptional regulation. Nat Rev Mol Cell Biol (2005) 1.66
The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing. Proc Natl Acad Sci U S A (2009) 1.62
Spectroscopic studies of position-specific DNA "breathing" fluctuations at replication forks and primer-template junctions. Proc Natl Acad Sci U S A (2009) 1.49
Mapping the conformation of the nucleic acid framework of the T7 RNA polymerase elongation complex in solution using low-energy CD and fluorescence spectroscopy. J Mol Biol (2006) 1.32
Assembly of an RNA-protein complex. Binding of NusB and NusE (S10) proteins to boxA RNA nucleates the formation of the antitermination complex involved in controlling rRNA transcription in Escherichia coli. J Biol Chem (2005) 1.17
Direct spectroscopic study of reconstituted transcription complexes reveals that intrinsic termination is driven primarily by thermodynamic destabilization of the nucleic acid framework. J Biol Chem (2007) 1.12
DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. Proc Natl Acad Sci U S A (2010) 1.12
Investigating local conformations of double-stranded DNA by low-energy circular dichroism of pyrrolo-cytosine. Proc Natl Acad Sci U S A (2005) 1.04
Breathing fluctuations in position-specific DNA base pairs are involved in regulating helicase movement into the replication fork. Proc Natl Acad Sci U S A (2012) 1.04
Local conformations and competitive binding affinities of single- and double-stranded primer-template DNA at the polymerization and editing active sites of DNA polymerases. J Biol Chem (2009) 1.02
Multiple ATP binding is required to stabilize the "activated" (clamp open) clamp loader of the T4 DNA replication complex. J Biol Chem (2008) 1.01
Single-molecule FRET and linear dichroism studies of DNA breathing and helicase binding at replication fork junctions. Proc Natl Acad Sci U S A (2013) 1.01
Assembly and subunit stoichiometry of the functional helicase-primase (primosome) complex of bacteriophage T4. Proc Natl Acad Sci U S A (2012) 1.01
Solution conformation of 2-aminopurine (2-AP) dinucleotide determined by ultraviolet 2D fluorescence spectroscopy (UV-2D FS). New J Phys (2013) 0.98
Characterization of the 6-methyl isoxanthopterin (6-MI) base analog dimer, a spectroscopic probe for monitoring guanine base conformations at specific sites in nucleic acids. Nucleic Acids Res (2011) 0.97
Low energy CD of RNA hairpin unveils a loop conformation required for lambdaN antitermination activity. J Biol Chem (2005) 0.96
A single-molecule view of the assembly pathway, subunit stoichiometry, and unwinding activity of the bacteriophage T4 primosome (helicase-primase) complex. Biochemistry (2013) 0.96
Helicases become mechanistically simpler and functionally more complex. Nat Struct Mol Biol (2004) 0.94
DNA models of trinucleotide frameshift deletions: the formation of loops and bulges at the primer-template junction. Nucleic Acids Res (2009) 0.91
Electronic transition moments of 6-methyl isoxanthopterin--a fluorescent analogue of the nucleic acid base guanine. Nucleic Acids Res (2012) 0.89
Old and new approaches to DNA breathing: Comments on "Fluctuations in the DNA double helix: A critical review" by M.D. Frank-Kamenetskii and S. Prakash. Phys Life Rev (2014) 0.88
Monitoring RNA transcription in real time by using surface plasmon resonance. Proc Natl Acad Sci U S A (2008) 0.88
Active Escherichia coli transcription elongation complexes are functionally homogeneous. J Mol Biol (2002) 0.86
Mechanistic studies of the T4 DNA (gp41) replication helicase: functional interactions of the C-terminal Tails of the helicase subunits with the T4 (gp59) helicase loader protein. J Mol Biol (2005) 0.85
Development of a "modular" scheme to describe the kinetics of transcript elongation by RNA polymerase. Biophys J (2011) 0.82
The antitermination activity of bacteriophage lambda N protein is controlled by the kinetics of an RNA-looping-facilitated interaction with the transcription complex. J Mol Biol (2008) 0.79
Fitting experimental transcription data with a comprehensive template-dependent modular kinetic model. Biophys J (2011) 0.79
A quantitative description of the binding states and in vitro function of antitermination protein N of bacteriophage lambda. J Mol Biol (2005) 0.78